This gene set contains 12 downregulated genes that were differentially expressed in five brain regions (amygdale, frontal cortex, striatum, nucleus acumbens, and hippocampus) in congenic mice strains in which inbred alcohol preferring (iP) chromosome 4 QTL interval was transferred to inbred non-alcohol preferring (iNP) mice strain (NP.P) mice. This study identified genes in the chromosome 4 QTL interval that affect alcoholic predisposition in these strain (NP.P) mice.
Whole Brain Gene Expression Correlates for POSTURE measured in BXD RI Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The POSTURE measures Morphine - Postural Effects under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
cocaine related behavior 7 (Cocrb7) spans 28.968906 - 78.968906 Mbp (NCBI Build 37) on Chr 6. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
QTL for METH responses for home cage activity on Chr6 at Met (13.99 Mbp , Build 37)
Description:
METH responses for home cage activity spans 0.00 - 38.99 Mbp (NCBI Build 37) on Chr6. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for cocaine related behavior on Chr6 at D6Mit183 (53.97 Mbp , Build 37)
Description:
cocaine related behavior spans 28.97 - 78.97 Mbp (NCBI Build 37) on Chr6. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr6 at D6Ncvs34 (54.50 Mbp , Build 37)
Description:
METH responses for body temperature spans 29.50 - 79.50 Mbp (NCBI Build 37) on Chr6. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Rats in separate cage with free choice of water or 10% (v/v) of ethanol; consumption scores (grams/kg/day) were averaged; the amounts of ethanol consumed every 3 days over three weeks. Additive QTL. Variance 11 , LOD 9.2 Peak Marker: D4Rat34 spans D4Mgh9(54828166) - D4Mit9(152570244). Strains were P, NP. Also known as Eoh1.
Authors:
Carr LG, Habegger K, Spence JP, Liu L, Lumeng L, Foroud T
QTL associated with SGC/Knj cross B6 QTL 2. The confidence interval is Chr6:19862686-71272769 bp,+strand
Authors:
Hamano Y, Tsukamoto K, Abe M, Sun GD, Zhang D, Fujii H, Matsuoka S, Tanaka M, Ishida-Okawara A, Tachikawa H, Nishimura H, Tokunaka K, Hirose S, Suzuki K
QTL associated with behavioral response to methamphetamines 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (17503004)
QTL associated with bladder tumor susceptibility 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (29701222)
Authors:
Higashi S, Murai T, Mori S, Kamoto T, Yoshitomi M, Arakawa Y, Makino S, Fukushima S, Yoshida O, Hiai H
QTL associated with cocaine induced activation 8. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (29701222)
QTL associated with circadian period of locomotor activity 9. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (51112078)
Authors:
Hofstetter JR, Trofatter JA, Kernek KL, Nurnberger JI, Mayeda AR
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