List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Urate levels. The EFO term urate measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Köttgen, E Albrecht, A Teumer, V Vitart, J Krumsiek, C Hundertmark, G Pistis, D Ruggiero, CM O'Seaghdha, T Haller, Q Yang, T Tanaka, AD Johnson, Z Kutalik, AV Smith, J Shi, M Struchalin, RP Middelberg, MJ Brown, AL Gaffo, N Pirastu, G Li, C Hayward, T Zemunik, J Huffman, L Yengo, JH Zhao, A Demirkan, MF Feitosa, X Liu, G Malerba, LM Lopez, P van der Harst, X Li, ME Kleber, AA Hicks, IM Nolte, A Johansson, F Murgia, SH Wild, SJ Bakker, JF Peden, A Dehghan, M Steri, A Tenesa, V Lagou, P Salo, M Mangino, LM Rose, T Lehtimäki, OM Woodward, Y Okada, A Tin, C Müller, C Oldmeadow, M Putku, D Czamara, P Kraft, L Frogheri, GA Thun, A Grotevendt, GK Gislason, TB Harris, LJ Launer, P McArdle, AR Shuldiner, E Boerwinkle, J Coresh, H Schmidt, M Schallert, NG Martin, GW Montgomery, M Kubo, Y Nakamura, T Tanaka, PB Munroe, NJ Samani, DR Jacobs, K Liu, P D'Adamo, S Ulivi, JI Rotter, BM Psaty, P Vollenweider, G Waeber, S Campbell, O Devuyst, P Navarro, I Kolcic, N Hastie, B Balkau, P Froguel, T Esko, A Salumets, KT Khaw, C Langenberg, NJ Wareham, A Isaacs, A Kraja, Q Zhang, PS Wild, RJ Scott, EG Holliday, E Org, M Viigimaa, S Bandinelli, JE Metter, A Lupo, E Trabetti, R Sorice, A Döring, E Lattka, K Strauch, F Theis, M Waldenberger, HE Wichmann, G Davies, AJ Gow, M Bruinenberg, RP Stolk, JS Kooner, W Zhang, BR Winkelmann, BO Boehm, S Lucae, BW Penninx, JH Smit, G Curhan, P Mudgal, RM Plenge, L Portas, I Persico, M Kirin, JF Wilson, I Mateo Leach, WH van Gilst, A Goel, H Ongen, A Hofman, F Rivadeneira, AG Uitterlinden, M Imboden, A von Eckardstein, F Cucca, R Nagaraja, MG Piras, M Nauck, C Schurmann, K Budde, F Ernst, SM Farrington, E Theodoratou, I Prokopenko, M Stumvoll, A Jula, M Perola, V Salomaa, SY Shin, TD Spector, C Sala, PM Ridker, M Kähönen, J Viikari, C Hengstenberg, CP Nelson, JF Meschia, MA Nalls, P Sharma, AB Singleton, N Kamatani, T Zeller, M Burnier, J Attia, M Laan, N Klopp, HL Hillege, S Kloiber, H Choi, M Pirastu, S Tore, NM Probst-Hensch, H Völzke, V Gudnason, A Parsa, R Schmidt, JB Whitfield, M Fornage, P Gasparini, DS Siscovick, O Polašek, H Campbell, I Rudan, N Bouatia-Naji, A Metspalu, RJ Loos, CM van Duijn, IB Borecki, L Ferrucci, G Gambaro, IJ Deary, BH Wolffenbuttel, JC Chambers, W März, PP Pramstaller, H Snieder, U Gyllensten, AF Wright, G Navis, H Watkins, JC Witteman, S Sanna, S Schipf, MG Dunlop, A Tönjes, S Ripatti, N Soranzo, D Toniolo, DI Chasman, O Raitakari, WH Kao, M Ciullo, CS Fox, M Caulfield, M Bochud, C Gieger
Neocortex Gene Expression Correlates for LD_PCT_DISTLIGHT measured in BXD RI Females obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The LD_PCT_DISTLIGHT measures Light-Dark Box Percentage of distance traveled in light compartment under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for ACTITOT_DIFF measured in BXD RI Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The ACTITOT_DIFF measures Difference in total distance traveled (cm) (saline-ethanol) under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for SPD_TIMEDOWEL0SEC measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The SPD_TIMEDOWEL0SEC measures Dowel Test - Time 0 Sec under the domain Porsolt. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for URINE measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The URINE measures Novel Open Field Number of urinations under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Fold change of the 74 common differentially expressed probe sets between LIMMA analysis in cohort A and LIMMA analysis in cohort B
Authors:
Arijs I, Li K, Toedter G, Quintens R, Van Lommel L, Van Steen K, Leemans P, De Hertogh G, Lemaire K, Ferrante M, Schnitzler F, Thorrez L, Ma K, Song XY, Marano C, Van Assche G, Vermeire S, Geboes K, Schuit F, Baribaud F, Rutgeerts P
QTL for nicotine sensitivity on Chr14 at D14Mit155 (49.05 Mbp , Build 37)
Description:
nicotine sensitivity spans 24.05 - 74.05 Mbp (NCBI Build 37) on Chr14. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for home cage activity on Chr14 at Gnrh (75.38 Mbp , Build 37)
Description:
METH responses for home cage activity spans 50.38 - 100.38 Mbp (NCBI Build 37) on Chr14. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for chronic alcohol withdrawal severity on Chr14 at D14mit160 (75.81 Mbp , Build 37)
Description:
chronic alcohol withdrawal severity spans 50.81 - 100.81 Mbp (NCBI Build 37) on Chr14. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Bergeson SE, Kyle Warren R, Crabbe JC, Metten P, Gene Erwin V, Belknap JK
QTL for METH responses for climbing on Chr14 at Es10 (78.19 Mbp , Build 37)
Description:
METH responses for climbing spans 53.19 - 103.19 Mbp (NCBI Build 37) on Chr14. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'entinostat' (C118739). Incorporates data from 11 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'ochratoxin A' (C025589). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Ovis aries that interact with the MeSH term '13beta-methyl 19-nor-steroid' (C422565). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Coumestrol' (D003375). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Uric Acid' (D014527). Incorporates data from 7 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'sorafenib' (C471405). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine' (C516138). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Thimerosal' (D013849). Incorporates data from 20 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Vitamin E' (D014810). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Authors:
None
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