A signal transducer and activator of transcription that mediates cellular responses to INTERFERONS. Stat1 interacts with P53 TUMOR SUPPRESSOR PROTEIN and regulates expression of GENES involved in growth control and APOPTOSIS.
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"Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat1 protein." [GOC:jl, PMID:10918594]
"Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat1 protein." [GOC:jl, PMID:10918594]
"Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat1 protein." [GOC:jl, PMID:10918594]
"Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat1 protein." [GOC:jl, PMID:10918594]
"Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat1 protein." [GOC:jl, PMID:10918594]
"Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat1 protein." [GOC:jl, PMID:10918594]
An interferon regulatory factor that recruits STAT1 PROTEIN and STAT2 PROTEIN heterodimers to interferon-stimulated response elements and functions as an immediate-early protein.
Generated by gene2mesh v. 1.1.1
A heterodimeric complex of STAT1 PROTEIN and STAT2 PROTEIN that interacts with ISGF3GAMMA and is a subunit of the ISGF3 COMPLEX.
Generated by gene2mesh v. 1.1.1
Signal transduction molecule genes that are upregulated in the presence of LPS and differentially expressed in response to CBD + LPS. Mouse BV-2 microglial cells were pretreated with 10 uM CBD for 2 h, followed by addition of LPS for an additional 4 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S2. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
Signal transduction molecule genes that are upregulated in the presence of LPS and differentially expressed in response to THC + LPS. Mouse BV-2 microglial cells were pretreated with 10 uM THC for 2 h, followed by addition of LPS for an additional 4 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S2. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
signal transduction molecule genes that are upregulated in the presence of LPS and differentially expressed in response to CBD. Mouse BV-2 microglial cells were pretreated with 10 uM CBD for 2 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S2. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
signal transduction molecule genes that are upregulated in the presence of LPS and differentially expressed in response to THC. Mouse BV-2 microglial cells were pretreated with 10 uM THC for 2 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S2. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
Neocortex Gene Expression Correlates for BEC measured in BXD RI Females & Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The BEC measures blood ethanol concentration in mg/dl under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HCOUNT30 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HCOUNT30 measures Open Field locomotion 15-30 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HCOUNT30 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HCOUNT30 measures Open Field locomotion 15-30 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HCOUNT45 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HCOUNT45 measures Open Field locomotion 30-45 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HCOUNT60 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HCOUNT60 measures Open Field locomotion 45-60 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HDIS30 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HDIS30 measures Open Field locomotion (cm) 15-30 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HDIS30 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HDIS30 measures Open Field locomotion (cm) 15-30 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Striatum Gene Expression Correlates for C1HDIS45 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The C1HDIS45 measures Open Field locomotion (cm) 30-45 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
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