QTL for high-dose ethanol actions on Chr9 at D9Mit42 (21.79 Mbp , Build 37)
Description:
high-dose ethanol actions spans 0.00 - 46.79 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Erwin VG, Markel PD, Johnson TE, Gehle VM, Jones BC
Alcohol preference QTL 1 spans 26931283-76931283 (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org). Phenotypically extreme HAP1/LAP1 animals (n=96) and HAP2/LAP2 animals (n=48) were screened for microsatellite markers in chromosomal regions previously reported to influence alcohol preference phenotypes. Linkage to alcohol preference, Alpq1, mapped to chromosome 9 near D9Mit4 (29 cM) in the HAP1/LAP1 set and near D9Mit90 (9 cM) in the HAP2/LAP2 set. The Alpq1 QTL interval is broad and may contain more than 1 underlying gene. Drd2 at 28 cM is a potential candidate for Alpq1.
Authors:
Bice PJ, Foroud T, Carr LG, Zhang L, Liu L, Grahame NJ, Lumeng L, Li TK, Belknap JK
Genes associated with Homo sapiens that interact with the MeSH term 'Melphalan' (D008558). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Platichthys flesus that interact with the MeSH term 'Cadmium Chloride' (D019256). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Vanadates' (D014638). Incorporates data from 150 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
BECs at LORR Recovery Chr# 9 rs13480854(7524005) with right flanking marker mCV23893269 (4062079) and left marker rs3663313 (123063108). This was mapped in 300 + (b6x129)F2 mice.
Ethanol Induced Ataxia Chr#9 rs3655717(65312971) with right flanking marker rs13480112(26413932) and left marker rs13480421(111761261). This was mapped in 300 + (b6x129)F2 mice.
QTL associated with activity-distance traveled 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (49331368)
QTL associated with activity response to ethanol 6. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (47439809)
Authors:
Malmanger B, Lawler M, Coulombe S, Murray R, Cooper S, Polyakov Y, Belknap J, Hitzemann R
QTL associated with APP associated premature death 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (40462577)
QTL associated with Alzheimer's disease modifier 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (65425671)
Authors:
Sebastiani G, Krzywkowski P, Dudal S, Yu M, Paquette J, Malo D, Gervais F, Tremblay P
QTL associated with bone response to mechanical loading 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (37202486)
QTL associated with castaneus 10 week body weight 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (37202486)
QTL associated with cystic fibrosis modifier QTL 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (32308040)
QTL associated with mean cell hemoglobin concentration QTL 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (49313165)
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