List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was QT interval. The EFO term QT interval was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JW Kim, KW Hong, MJ Go, SS Kim, Y Tabara, Y Kita, T Tanigawa, YS Cho, BG Han, B Oh
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Electrocardiographic traits. The EFO term PR interval was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Sano, S Kamitsuji, N Kamatani, KW Hong, BG Han, Y Kim, JW Kim, Y Aizawa, K Fukuda
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was PR interval. The EFO term PR interval was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
KW Hong, JE Lim, JW Kim, Y Tabara, H Ueshima, T Miki, F Matsuda, YS Cho, Y Kim, B Oh
Genes associated with Homo sapiens that interact with the MeSH term 'Antirheumatic Agents' (D018501). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with nan that interact with the MeSH term 'Serotonin Agents' (D018490). Incorporates data from 4198 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Electrocardiographic traits. The EFO term QT interval was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Sano, S Kamitsuji, N Kamatani, KW Hong, BG Han, Y Kim, JW Kim, Y Aizawa, K Fukuda
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Electrocardiographic traits. The EFO term QRS duration was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Sano, S Kamitsuji, N Kamatani, KW Hong, BG Han, Y Kim, JW Kim, Y Aizawa, K Fukuda
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Asthma (childhood onset). The EFO term asthma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
B Almoguera, L Vazquez, F Mentch, J Connolly, JA Pacheco, AS Sundaresan, PL Peissig, JG Linneman, CA McCarty, D Crosslin, DS Carrell, T Lingren, B Namjou-Khales, JB Harley, E Larson, GP Jarvik, M Brilliant, MS Williams, IJ Kullo, EB Hysinger, PM Sleiman, H Hakonarson
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was QT interval. The EFO term QT interval was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
DE Arking, SL Pulit, L Crotti, P van der Harst, PB Munroe, TT Koopmann, N Sotoodehnia, EJ Rossin, M Morley, X Wang, AD Johnson, A Lundby, DF Gudbjartsson, PA Noseworthy, M Eijgelsheim, Y Bradford, KV Tarasov, M Dörr, M Müller-Nurasyid, AM Lahtinen, IM Nolte, AV Smith, JC Bis, A Isaacs, SJ Newhouse, DS Evans, WS Post, D Waggott, LP Lyytikäinen, AA Hicks, L Eisele, D Ellinghaus, C Hayward, P Navarro, S Ulivi, T Tanaka, DJ Tester, S Chatel, S Gustafsson, M Kumari, RW Morris, ÅT Naluai, S Padmanabhan, A Kluttig, B Strohmer, AG Panayiotou, M Torres, M Knoflach, JA Hubacek, K Slowikowski, S Raychaudhuri, RD Kumar, TB Harris, LJ Launer, AR Shuldiner, A Alonso, JS Bader, G Ehret, H Huang, WH Kao, JB Strait, PW Macfarlane, M Brown, MJ Caulfield, NJ Samani, F Kronenberg, J Willeit, JG Smith, KH Greiser, H Meyer Zu Schwabedissen, K Werdan, M Carella, L Zelante, SR Heckbert, BM Psaty, JI Rotter, I Kolcic, O Polašek, AF Wright, M Griffin, MJ Daly, DO Arnar, H Hólm, U Thorsteinsdottir, JC Denny, DM Roden, RL Zuvich, V Emilsson, AS Plump, MG Larson, CJ O'Donnell, X Yin, M Bobbo, AP D'Adamo, A Iorio, G Sinagra, A Carracedo, SR Cummings, MA Nalls, A Jula, KK Kontula, A Marjamaa, L Oikarinen, M Perola, K Porthan, R Erbel, P Hoffmann, KH Jöckel, H Kälsch, MM Nöthen, M den Hoed, RJ Loos, DS Thelle, C Gieger, T Meitinger, S Perz, A Peters, H Prucha, MF Sinner, M Waldenberger, RA de Boer, L Franke, PA van der Vleuten, BM Beckmann, E Martens, A Bardai, N Hofman, AA Wilde, ER Behr, C Dalageorgou, JR Giudicessi, A Medeiros-Domingo, J Barc, F Kyndt, V Probst, A Ghidoni, R Insolia, RM Hamilton, SW Scherer, J Brandimarto, K Margulies, CE Moravec, F del Greco M, C Fuchsberger, JR O'Connell, WK Lee, GC Watt, H Campbell, SH Wild, NE El Mokhtari, N Frey, FW Asselbergs, I Mateo Leach, G Navis, MP van den Berg, DJ van Veldhuisen, M Kellis, BP Krijthe, OH Franco, A Hofman, JA Kors, AG Uitterlinden, JC Witteman, L Kedenko, C Lamina, BA Oostra, GR Abecasis, EG Lakatta, A Mulas, M Orrú, D Schlessinger, M Uda, MR Markus, U Völker, H Snieder, TD Spector, J Ärnlöv, L Lind, J Sundström, AC Syvänen, M Kivimaki, M Kähönen, N Mononen, OT Raitakari, JS Viikari, V Adamkova, S Kiechl, M Brion, AN Nicolaides, B Paulweber, J Haerting, AF Dominiczak, F Nyberg, PH Whincup, AD Hingorani, JJ Schott, CR Bezzina, E Ingelsson, L Ferrucci, P Gasparini, JF Wilson, I Rudan, A Franke, TW Mühleisen, PP Pramstaller, TJ Lehtimäki, AD Paterson, A Parsa, Y Liu, CM van Duijn, DS Siscovick, V Gudnason, Y Jamshidi, V Salomaa, SB Felix, S Sanna, MD Ritchie, BH Stricker, K Stefansson, LA Boyer, TP Cappola, JV Olsen, K Lage, PJ Schwartz, S Kääb, A Chakravarti, MJ Ackerman, A Pfeufer, PI de Bakker, C Newton-Cheh
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was HIV-associated dementia. The EFO term AIDS dementia was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
AJ Levine, S Service, EN Miller, SM Reynolds, EJ Singer, P Shapshak, EM Martin, N Sacktor, JT Becker, LP Jacobson, P Thompson, N Freimer
The total transcriptome including genes that are differentially expressed in cocaine addicts compared to control subjects. Post-mortem brain samples were collected from the dorsolateral prefrontal cortex (dlPFC) of the cocaine addict group and the control group. To assess gene expression, RNA-seq was performed. Data taken from Supplementary Table 2. Values presented are k.diff values. Data available from GEO with accession number GSE99349."
Authors:
Efrain A Ribeiro, Joseph R Scarpa, Susanna P Garamszegi, Andrew Kasarskis, Deborah C Mash, Eric J Nestler
Data from GEO GSE194368 and analyzed using GEO2R, only top gene shown. Authors identified transcriptional adaptations of GR signaling in the amygdala of humans with OUD. Thus, GRs, their coregulators and downstream systems may represent viable therapeutic targets to treat the “stress side” of OUD.
Authors:
Stephanie A Carmack, Janaina C M Vendruscolo, M Adrienne McGinn, Jorge Miranda-Barrientos, Vez Repunte-Canonigo, Gabriel D Bosse, Daniele Mercatelli, Federico M Giorgi, Yu Fu, Anthony J Hinrich, Francine M Jodelka, Karen Ling, Robert O Messing, Randall T Peterson, Frank Rigo, Scott Edwards, Pietro P Sanna, Marisela Morales, Michelle L Hastings, George F Koob, Leandro F Vendruscolo
Differential gene expression between CS15 and CS22 - Adj-P value
Description:
Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17 and CS22. Here the differential expression comparison between CS15 and CS22 is shown. Gene expressions values, Ensembl Gene ids and the corresponding Adjusted P value are presented. UBERON:0015789, cranial or facial muscle.
Authors:
Tara N Yankee, Sungryong Oh, Emma Wentworth Winchester, Andrea Wilderman, Kelsey Robinson, Tia Gordon, Jill A Rosenfeld, Jennifer VanOudenhove, Daryl A Scott, Elizabeth J Leslie, Justin Cotney
Differential gene expression between CS13 and CS22 - Log2FC
Description:
Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17, and CS22. Here the differential expression comparison between CS13 and CS22 is shown. Gene expressions values with log to the base 2, FC are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Authors:
Tara N Yankee, Sungryong Oh, Emma Wentworth Winchester, Andrea Wilderman, Kelsey Robinson, Tia Gordon, Jill A Rosenfeld, Jennifer VanOudenhove, Daryl A Scott, Elizabeth J Leslie, Justin Cotney
Differential gene expression between CS13 and CS22 - Adj-P value
Description:
Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17 and CS22. Here the differential expression comparison between CS13 and CS22 is shown. Gene expressions values, Ensembl Gene ids and the corresponding Adjusted P value are presented. UBERON:0015789, cranial or facial muscle.
Authors:
Tara N Yankee, Sungryong Oh, Emma Wentworth Winchester, Andrea Wilderman, Kelsey Robinson, Tia Gordon, Jill A Rosenfeld, Jennifer VanOudenhove, Daryl A Scott, Elizabeth J Leslie, Justin Cotney
Differential gene expression between CS14 and CS22 - Adj-P value
Description:
Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17 and CS22. Here the differential expression comparison between CS14 and CS22 is shown. Gene expressions values, Ensembl Gene ids and the corresponding Adjusted P value are presented. UBERON:0015789, cranial or facial muscle.
Authors:
Tara N Yankee, Sungryong Oh, Emma Wentworth Winchester, Andrea Wilderman, Kelsey Robinson, Tia Gordon, Jill A Rosenfeld, Jennifer VanOudenhove, Daryl A Scott, Elizabeth J Leslie, Justin Cotney
Differential gene expression between CS14 and CS22 - Adj-P value
Description:
Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17 and CS22. Here the differential expression comparison between CS14 and CS22 is shown. Gene expressions values, Ensembl Gene ids and the corresponding Adjusted P value are presented. UBERON:0015789, cranial or facial muscle.
Authors:
Tara N Yankee, Sungryong Oh, Emma Wentworth Winchester, Andrea Wilderman, Kelsey Robinson, Tia Gordon, Jill A Rosenfeld, Jennifer VanOudenhove, Daryl A Scott, Elizabeth J Leslie, Justin Cotney
This gene set comprises 399 genes that are differentially expressed within each of five brain regions (amygdale, hippocampus, nucleus accumbens, prefrontal cortex and ventral tegmental area) when chronic nicotine treatment is administered to C3H/HeJ mice only. Background: Studies involving use of chronic nicotine treatment identify unique nicotine addiction genes and the biological processes they control in B6 and C3 mice. Results are obtained using gene expression profiling and gene ontology.
Authors:
Wang J, Gutala R, Hwang YY, Kim JM, Konu O, Ma JZ, Li MD
This gene set comprises 239 genes that are differentially expressed within each of five brain regions (amygdala, hippocampus, nucleus accumbens, prefrontal cortex and ventral tegmental area) when chronic nicotine treatment is administered to C57BL/6J mice only. Background: Studies involving use of chronic nicotine treatment identify unique nicotine addiction genes and the biological processes they control in B6 and C3 mice. Results are obtained using gene expression profiling and gene ontology.
Authors:
Wang J, Gutala R, Hwang YY, Kim JM, Konu O, Ma JZ, Li MD
This gene set comprises 66 genes that are upregulated within each of five brain regions (amygdale, hippocampus, nucleus accumbens, prefrontal cortex and ventral tegmental area) when chronic nicotine treatment is administered to B6 mice only. Background: Studies involving chronic nicotine treatment identify unique nicotine addiction genes and the biological processes they mediate in C3 and B6 mice. Results are obtained using gene expression profiling via cDNA microarrays and gene ontology.
Authors:
Wang J, Gutala R, Hwang YY, Kim JM, Konu O, Ma JZ, Li MD
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