QTL for METH responses for home cage activity on Chr3 at Evi1 (30.85 Mbp , Build 37)
Description:
METH responses for home cage activity spans 5.85 - 55.85 Mbp (NCBI Build 37) on Chr3. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'Arsenic' (D001151). Incorporates data from 87 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Cricetulus griseus that interact with the MeSH term 'Endosulfan' (D004726). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Aflatoxin B1' (D016604). Incorporates data from 5 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Vanadates' (D014638). Incorporates data from 150 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryzias latipes that interact with the MeSH term 'Tetrachlorodibenzodioxin' (D013749). Incorporates data from 41 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
QTL associated with experimental allergic encephalomyelitis susceptibility 20. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (28475226)
QTL associated with HIV-associated nephropathy 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (24235798)
QTL associated with thymocyte proliferative response 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (21370177)
Authors:
Hsu HC, Mountz JD, Williams RW, Shelton BJ, Yang PA, Matsuki Y, Xu X, Dodd CH, Li L, Geiger H, Zhang HG, Van Zant G
"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in)." [TC:2.A.28.-.-]
"Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other." [GOC:jid, GOC:mtg_transport, ISBN:0815340729]
"Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells." [GOC:mtg_transport]
"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in)." [TC:2.A.28.-.-]
"Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other." [GOC:jid, GOC:mtg_transport, ISBN:0815340729]
"Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells." [GOC:mtg_transport]
As a treatment of ulcerative colitis the entire large bowel is resected, and the unaffected small bowel is used to create a reservoir (pouch) connected to the anal canal [restorative proctocolectomy with an ileal pouch–anal anastomosis (IPAA)]. Pouch inflammation, “pouchitis,” is the most prevalent long-term complication in patients with UC, with a reported incidence of up to 60%. Approximatly 490 transcripts were differentially expressed in chronic pouchitis compared to normal controls. P value uploaded.
Authors:
Ben-Shachar S, Yanai H, Baram L, Elad H, Meirovithz E, Ofer A, Brazowski E, Tulchinsky H, Pasmanik-Chor M, Dotan I
As a treatment of ulcerative colitis the entire large bowel is resected, and the unaffected small bowel is used to create a reservoir (pouch) connected to the anal canal [restorative proctocolectomy with an ileal pouch–anal anastomosis (IPAA)]. Crohn’s-like disease of the pouch (CLDP) such as fistulas, strictures, or inflammation of ileal segments proximal to the pouchpatients with CLDP had 1152 significantly altered transcripts compared with NC. P-value uploaded.
Authors:
Ben-Shachar S, Yanai H, Baram L, Elad H, Meirovithz E, Ofer A, Brazowski E, Tulchinsky H, Pasmanik-Chor M, Dotan I
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