List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Brugada syndrome. The EFO term Brugada syndrome was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was QRS duration. The EFO term QRS duration was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
DS Evans, CL Avery, MA Nalls, G Li, J Barnard, EN Smith, T Tanaka, AM Butler, SG Buxbaum, A Alonso, DE Arking, GS Berenson, JC Bis, S Buyske, CL Carty, W Chen, MK Chung, SR Cummings, R Deo, CB Eaton, ER Fox, SR Heckbert, G Heiss, LA Hindorff, WC Hsueh, A Isaacs, Y Jamshidi, KF Kerr, F Liu, Y Liu, KK Lohman, JW Magnani, JF Maher, R Mehra, YA Meng, SK Musani, C Newton-Cheh, KE North, BM Psaty, S Redline, JI Rotter, RB Schnabel, NJ Schork, RV Shohet, AB Singleton, JD Smith, EZ Soliman, SR Srinivasan, HA Taylor, DR Van Wagoner, JG Wilson, T Young, ZM Zhang, AB Zonderman, MK Evans, L Ferrucci, SS Murray, GJ Tranah, EA Whitsel, AP Reiner, N Sotoodehnia
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was PR interval. The EFO term PR interval was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Pfeufer, C van Noord, KD Marciante, DE Arking, MG Larson, AV Smith, KV Tarasov, M Müller, N Sotoodehnia, MF Sinner, GC Verwoert, M Li, WH Kao, A Köttgen, J Coresh, JC Bis, BM Psaty, K Rice, JI Rotter, F Rivadeneira, A Hofman, JA Kors, BH Stricker, AG Uitterlinden, CM van Duijn, BM Beckmann, W Sauter, C Gieger, SA Lubitz, C Newton-Cheh, TJ Wang, JW Magnani, RB Schnabel, MK Chung, J Barnard, JD Smith, DR Van Wagoner, RS Vasan, T Aspelund, G Eiriksdottir, TB Harris, LJ Launer, SS Najjar, E Lakatta, D Schlessinger, M Uda, GR Abecasis, B Müller-Myhsok, GB Ehret, E Boerwinkle, A Chakravarti, EZ Soliman, KL Lunetta, S Perz, HE Wichmann, T Meitinger, D Levy, V Gudnason, PT Ellinor, S Sanna, S Kääb, JC Witteman, A Alonso, EJ Benjamin, SR Heckbert
A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of CARDIOMYOCYTES. Defects in the SCN5A gene, which codes for the alpha subunit of this sodium channel, are associated with a variety of CARDIAC DISEASES that result from loss of sodium channel function.
Generated by gene2mesh v. 1.1.1
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was QT interval. The EFO term QT interval was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
C Newton-Cheh, M Eijgelsheim, KM Rice, PI de Bakker, X Yin, K Estrada, JC Bis, K Marciante, F Rivadeneira, PA Noseworthy, N Sotoodehnia, NL Smith, JI Rotter, JA Kors, JC Witteman, A Hofman, SR Heckbert, CJ O'Donnell, AG Uitterlinden, BM Psaty, T Lumley, MG Larson, BH Stricker
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was QT interval. The EFO term QT interval was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Pfeufer, S Sanna, DE Arking, M Müller, V Gateva, C Fuchsberger, GB Ehret, M Orrú, C Pattaro, A Köttgen, S Perz, G Usala, M Barbalic, M Li, B Pütz, A Scuteri, RJ Prineas, MF Sinner, C Gieger, SS Najjar, WH Kao, TW Mühleisen, M Dei, C Happle, S Möhlenkamp, L Crisponi, R Erbel, KH Jöckel, S Naitza, G Steinbeck, F Marroni, AA Hicks, E Lakatta, B Müller-Myhsok, PP Pramstaller, HE Wichmann, D Schlessinger, E Boerwinkle, T Meitinger, M Uda, J Coresh, S Kääb, GR Abecasis, A Chakravarti
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was PR interval. The EFO term PR interval was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JG Smith, JW Magnani, C Palmer, YA Meng, EZ Soliman, SK Musani, KF Kerr, RB Schnabel, SA Lubitz, N Sotoodehnia, S Redline, A Pfeufer, M Müller, DS Evans, MA Nalls, Y Liu, AB Newman, AB Zonderman, MK Evans, R Deo, PT Ellinor, DN Paltoo, C Newton-Cheh, EJ Benjamin, R Mehra, A Alonso, SR Heckbert, ER Fox
Positional candidate genes for VONFREYTHRESHOLDMEAN in BXD RI Females & Males on Chr9
Description:
Position candidates for VONFREYTHRESHOLDMEAN measured in BXD RI Females & Males. VONFREYTHRESHOLDMEAN measures Mechanical Sensitivity-Von Frey Threshold under the domain Pain. The QTL found was a Suggestive QTL and spans 114 Mb to 120 Mb.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
cocaine related behavior 10 (Cocrb10) spans 93.149752 - 143.149752 Mbp (NCBI Build 37) on Chr 9. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
QTL for differences in cocaine responsiveness on Chr9 at D9M!t12 (94.40 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 69.40 - 119.40 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr9 at D9Mit12 (103.09 Mbp , Build 37)
Description:
METH responses for body temperature spans 78.09 - 128.09 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
alcohol response 4 (a.k.a. high-dose ethanol actions) is associated with neurotensin immunoreactivity and sleep time after alcohol administration mapped to 55 cM on mouse Chromosome 9 near D9Mit12 (P=0.0006). This locus is named Alcrsp4 (alcohol response 4). Potential candidate genes found in this region are Chrna3 and Gnai2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Erwin VG, Markel PD, Johnson TE, Gehle VM, Jones BC
QTL for differences in cocaine responsiveness on Chr9 at D9MIt2O (105.59 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 80.59 - 130.59 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for cocaine seizure on Chr9 at D9Mit51 (111.26 Mbp , Build 37)
Description:
cocaine seizure spans 86.26 - 136.26 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for home cage activity on Chr9 at D9Ncvs17 (114.61 Mbp , Build 37)
Description:
METH responses for home cage activity spans 89.61 - 139.61 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for cocaine related behavior on Chr9 at D9Ncvs45 (118.15 Mbp , Build 37)
Description:
cocaine related behavior spans 93.15 - 143.15 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr9 at Cck (118.82 Mbp , Build 37)
Description:
METH responses for body temperature spans 93.82 - 143.82 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr9 at D9Byu6 (118.82 Mbp , Build 37)
Description:
METH responses for body temperature spans 93.82 - 143.82 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for ethanol withdrawal on Chr9 at D9Byu6 (118.82 Mbp , Build 37)
Description:
ethanol withdrawal spans 93.82 - 143.82 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for chewing on Chr9 at Tel9q (123.39 Mbp , Build 37)
Description:
METH responses for chewing spans 98.39 - 148.39 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term '1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene' (C105351). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '5-dihydrocortisone' (C045993). Incorporates data from 1538 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'Mexiletine' (D008801). Incorporates data from 15 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Bromosuccinimide' (D001974). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
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