List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Obesity. The EFO term obesity was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
SI Berndt, S Gustafsson, R Mägi, A Ganna, E Wheeler, MF Feitosa, AE Justice, KL Monda, DC Croteau-Chonka, FR Day, T Esko, T Fall, T Ferreira, D Gentilini, AU Jackson, J Luan, JC Randall, S Vedantam, CJ Willer, TW Winkler, AR Wood, T Workalemahu, YJ Hu, SH Lee, L Liang, DY Lin, JL Min, BM Neale, G Thorleifsson, J Yang, E Albrecht, N Amin, JL Bragg-Gresham, G Cadby, M den Heijer, N Eklund, K Fischer, A Goel, JJ Hottenga, JE Huffman, I Jarick, Å Johansson, T Johnson, S Kanoni, ME Kleber, IR König, K Kristiansson, Z Kutalik, C Lamina, C Lecoeur, G Li, M Mangino, WL McArdle, C Medina-Gomez, M Müller-Nurasyid, JS Ngwa, IM Nolte, L Paternoster, S Pechlivanis, M Perola, MJ Peters, M Preuss, LM Rose, J Shi, D Shungin, AV Smith, RJ Strawbridge, I Surakka, A Teumer, MD Trip, J Tyrer, JV Van Vliet-Ostaptchouk, L Vandenput, LL Waite, JH Zhao, D Absher, FW Asselbergs, M Atalay, AP Attwood, AJ Balmforth, H Basart, J Beilby, LL Bonnycastle, P Brambilla, M Bruinenberg, H Campbell, DI Chasman, PS Chines, FS Collins, JM Connell, WO Cookson, U de Faire, F de Vegt, M Dei, M Dimitriou, S Edkins, K Estrada, DM Evans, M Farrall, MM Ferrario, J Ferrières, L Franke, F Frau, PV Gejman, H Grallert, H Grönberg, V Gudnason, AS Hall, P Hall, AL Hartikainen, C Hayward, NL Heard-Costa, AC Heath, J Hebebrand, G Homuth, FB Hu, SE Hunt, E Hyppönen, C Iribarren, KB Jacobs, JO Jansson, A Jula, M Kähönen, S Kathiresan, F Kee, KT Khaw, M Kivimäki, W Koenig, AT Kraja, M Kumari, K Kuulasmaa, J Kuusisto, JH Laitinen, TA Lakka, C Langenberg, LJ Launer, L Lind, J Lindström, J Liu, A Liuzzi, ML Lokki, M Lorentzon, PA Madden, PK Magnusson, P Manunta, D Marek, W März, I Mateo Leach, B McKnight, SE Medland, E Mihailov, L Milani, GW Montgomery, V Mooser, TW Mühleisen, PB Munroe, AW Musk, N Narisu, G Navis, G Nicholson, EA Nohr, KK Ong, BA Oostra, CN Palmer, A Palotie, JF Peden, N Pedersen, A Peters, O Polasek, A Pouta, PP Pramstaller, I Prokopenko, C Pütter, A Radhakrishnan, O Raitakari, A Rendon, F Rivadeneira, I Rudan, TE Saaristo, JG Sambrook, AR Sanders, S Sanna, J Saramies, S Schipf, S Schreiber, H Schunkert, SY Shin, S Signorini, J Sinisalo, B Skrobek, N Soranzo, A Stančáková, K Stark, JC Stephens, K Stirrups, RP Stolk, M Stumvoll, AJ Swift, EV Theodoraki, B Thorand, DA Tregouet, E Tremoli, MM Van der Klauw, JB van Meurs, SH Vermeulen, J Viikari, J Virtamo, V Vitart, G Waeber, Z Wang, E Widén, SH Wild, G Willemsen, BR Winkelmann, JC Witteman, BH Wolffenbuttel, A Wong, AF Wright, MC Zillikens, P Amouyel, BO Boehm, E Boerwinkle, DI Boomsma, MJ Caulfield, SJ Chanock, LA Cupples, D Cusi, GV Dedoussis, J Erdmann, JG Eriksson, PW Franks, P Froguel, C Gieger, U Gyllensten, A Hamsten, TB Harris, C Hengstenberg, AA Hicks, A Hingorani, A Hinney, A Hofman, KG Hovingh, K Hveem, T Illig, MR Jarvelin, KH Jöckel, SM Keinanen-Kiukaanniemi, LA Kiemeney, D Kuh, M Laakso, T Lehtimäki, DF Levinson, NG Martin, A Metspalu, AD Morris, MS Nieminen, I Njølstad, C Ohlsson, AJ Oldehinkel, WH Ouwehand, LJ Palmer, B Penninx, C Power, MA Province, BM Psaty, L Qi, R Rauramaa, PM Ridker, S Ripatti, V Salomaa, NJ Samani, H Snieder, TI Sørensen, TD Spector, K Stefansson, A Tönjes, J Tuomilehto, AG Uitterlinden, M Uusitupa, P van der Harst, P Vollenweider, H Wallaschofski, NJ Wareham, H Watkins, HE Wichmann, JF Wilson, GR Abecasis, TL Assimes, I Barroso, M Boehnke, IB Borecki, P Deloukas, CS Fox, T Frayling, LC Groop, T Haritunian, IM Heid, D Hunter, RC Kaplan, F Karpe, MF Moffatt, KL Mohlke, JR O'Connell, Y Pawitan, EE Schadt, D Schlessinger, V Steinthorsdottir, DP Strachan, U Thorsteinsdottir, CM van Duijn, PM Visscher, AM Di Blasio, JN Hirschhorn, CM Lindgren, AP Morris, D Meyre, A Scherag, MI McCarthy, EK Speliotes, KE North, RJ Loos, E Ingelsson
Neocortex Gene Expression Correlates for HARGREAVES_MEANBOTH measured in BXD RI Females obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The HARGREAVES_MEANBOTH measures Thermal Nociception Hargreaves' Test under the domain Pain. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Neocortex Gene Expression Correlates for ACTI_DIFF_20 measured in BXD RI Females obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The ACTI_DIFF_20 measures Difference in distance traveled (cm) during the first last min (saline-ethanol) under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for LM_CUE_ACTIVITY measured in BXD RI Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The LM_CUE_ACTIVITY measures Activity in altered context during presentation of cue under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for LM_CUE_SUPPRESS measured in BXD RI Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The LM_CUE_SUPPRESS measures Suppression of activity in altered context under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for NEPDIST45 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEPDIST45 measures Novel environment locomotion (cm) 30-45 min in the periphery under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for NEPDIST45 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEPDIST45 measures Novel environment locomotion (cm) 30-45 min in the periphery under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Striatum Gene Expression Correlates for NEPDIST45 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEPDIST45 measures Novel environment locomotion (cm) 30-45 min in the periphery under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Whole Brain Gene Expression Correlates for AMCNT180 measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The AMCNT180 measures Morphine photocell counts minutes 165-180 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Neocortex Gene Expression Correlates for LM_PAIR1 measured in BXD RI Females & Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The LM_PAIR1 measures Activity during 1st tone shock pairing under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Neocortex Gene Expression Correlates for LM_PAIR1 measured in BXD RI Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The LM_PAIR1 measures Activity during 1st tone shock pairing under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for LM_PAIR2 measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The LM_PAIR2 measures Activity during 2ndtone shock pairing under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for OF_REAR_10_15 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The OF_REAR_10_15 measures Open Field - Total rears 10-15 minutes under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for OF_REAR_15_20 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The OF_REAR_15_20 measures Open Field - Total rears 15-20 minutes under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for OF_REAR_5_10 measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The OF_REAR_5_10 measures Open Field - Total rears 5-10 minutes under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for OF_REAR_5_10 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The OF_REAR_5_10 measures Open Field - Total rears 5-10 minutes under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for OF_REARS measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The OF_REARS measures Open Field - Total number of Rears under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for OF_REARS measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The OF_REARS measures Open Field - Total number of Rears under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Piechota M, Korostynski M, Solecki W, Gieryk A, Slezak M, Bilecki W, Ziolkowska B, Kostrzewa E, Cymerman I, Swiech L, Jaworski J, Przewlocki R
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