GWAS: insulin sensitivity measurement, body mass index
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Modified Stumvoll Insulin Sensitivity Index (interaction with BMI). The EFO term insulin sensitivity measurement, body mass index was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
GA Walford, S Gustafsson, D Rybin, A Stančáková, H Chen, CT Liu, J Hong, RA Jensen, K Rice, AP Morris, R Mägi, A Tönjes, I Prokopenko, ME Kleber, G Delgado, G Silbernagel, AU Jackson, EV Appel, N Grarup, JP Lewis, ME Montasser, C Landenvall, H Staiger, J Luan, TM Frayling, MN Weedon, W Xie, S Morcillo, MT Martínez-Larrad, ML Biggs, YD Chen, A Corbaton-Anchuelo, K Færch, JM Gómez-Zumaquero, MO Goodarzi, JR Kizer, HA Koistinen, A Leong, L Lind, C Lindgren, F Machicao, AK Manning, GM Martín-Núñez, G Rojo-Martínez, JI Rotter, DS Siscovick, JM Zmuda, Z Zhang, M Serrano-Rios, U Smith, F Soriguer, T Hansen, TJ Jørgensen, A Linnenberg, O Pedersen, M Walker, C Langenberg, RA Scott, NJ Wareham, A Fritsche, HU Häring, N Stefan, L Groop, JR O'Connell, M Boehnke, RN Bergman, FS Collins, KL Mohlke, J Tuomilehto, W März, P Kovacs, M Stumvoll, BM Psaty, J Kuusisto, M Laakso, JB Meigs, J Dupuis, E Ingelsson, JC Florez
Neocortex Gene Expression Correlates for HAND_BASELINE measured in BXD RI Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The HAND_BASELINE measures Handling induced convulsion baseline under the domain Ethanol HIC. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
cocaine related behavior 1 (Cocrb1) spans 79.870166 - 121.405905 Mbp (NCBI Build 37) on Chr 1. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
QTL for METH responses for body temperature on Chr1 at D1Ncvs75 (79.87 Mbp , Build 37)
Description:
METH responses for body temperature spans 54.87 - 104.87 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for chronic alcohol withdrawal severity on Chr1 at D1Mit46 (83.89 Mbp , Build 37)
Description:
chronic alcohol withdrawal severity spans 58.89 - 108.89 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Bergeson SE, Kyle Warren R, Crabbe JC, Metten P, Gene Erwin V, Belknap JK
QTL for METH responses for home cage activity on Chr1 at D1Ncvs41 (101.77 Mbp , Build 37)
Description:
METH responses for home cage activity spans 76.77 - 126.77 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'Ionomycin' (D015759). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Plant Extracts' (D010936). Incorporates data from 489 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'Tetradecanoylphorbol Acetate' (D013755). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Silicon Dioxide' (D012822). Incorporates data from 9 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
QTL associated with activity-distance traveled 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (103894727)
QTL associated with B.burgdorferi-associated arthritis 11. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (65896421)
Authors:
Roper RJ, Weis JJ, McCracken BA, Green CB, Ma Y, Weber KS, Fairbairn D, Butterfield RJ, Potter MR, Zachary JF, Doerge RW, Teuscher C
QTL associated with bone response to mechanical loading 8. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (78202934)
QTL associated with cyclophosphamide induced apoptosis. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (66992757)
Authors:
Bergman ML, Cilio CM, Penha-Gonalves C, Lamhamedi-Cherradi SE, Lfgren A, Colucci F, Lejon K, Garchon HJ, Holmberg D
QTL associated with cytokine deficiency colitis susceptibility 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (65899760)
QTL associated with cocaine induced activation 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (88315827)
QTL associated with dependence on morphine QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (90464815)
QTL associated with darker modification of yellow agouti QTL 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (73734337)
QTL associated with "early growth rate, maternal effect 1". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (74999392)
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