QTL for cocaine induced activation on Chr17 at D17MIT164 (6.59 Mbp , Build 37)
Description:
cocaine induced activation spans 0.00 - 31.59 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for ethanol metabolism rate on Chr17 at NA (9.40 Mbp , Build 37)
Description:
ethanol metabolism rate spans 0.00 - 34.40 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Grisel JE, Metten P, Wenger CD, Merrill CM, Crabbe JC
QTL for METH responses for body temperature on Chr17 at Zfp40 (17.81 Mbp , Build 37)
Description:
METH responses for body temperature spans 0.00 - 42.81 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for ethanol conditioned taste aversion on Chr17 at D17Ncvs39 (23.83 Mbp , Build 37)
Description:
ethanol conditioned taste aversion spans 0.00 - 48.83 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'chromium hexavalent ion' (C074702). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Tretinoin' (D014212). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Ovis aries that interact with the MeSH term 'Progesterone' (D011374). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester' (C070379). Incorporates data from 16 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Bos taurus that interact with the MeSH term 'diphenyliodonium' (C031291). Incorporates data from 9 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'FuMi protocol' (C074694). Incorporates data from 171 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Silicon Dioxide' (D012822). Incorporates data from 9 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Ethanol Induced Ataxia Chr#17 rs3672987(33247165) with right flanking marker rs4136382(3388912) and left marker rs3715723(58810428). This was mapped in 300 + (b6x129)F2 mice.
Using literature search and bioinformatics tools, the present study characterizes the genes involved in alcohol induced liver injury. Pubmed search for the terms ‘alcohol, liver, genes’ yielded 1323 results. We selected 75 references involving almost 85 genes. Since a large number of studies in literature have documented alcohol me- diated liver injury, the study has been limited to certain specific alco- hol regulated genes which have been extensively studied in this context or have very profound implications on the occurrence of alco- hol induced liver injury. The human homologues of the genes expressed in the rodent an- imals were selected from the database of Human Gene Nomenclature Committee. Further, the ToppFun bioinformatics tool was used to study the various parameters. Sixteen diseases in which alcohol regu- lated hepatic genes were observed and all of them were significant. The database search yielded 1206 drugs which are metabolized by al- cohol responsive genes in liver, 586 drugs were significant and 83 drugs have been represented. A list of 569 metabolic processes cata- lyzed by alcohol responsive genes in liver was observed, of which 314 were significant and 50 metabolic processes are represented. Al- cohol regulated genes in liver were found to exhibit 48 molecular functions but 9 were insignificant. Alcohol regulated hepatic genes were found to metabolize 30 biological pathways, of which 21 were significant. Bonferroni's method was used to analyze the significance of the bioinformatics data and p < 0.05 was considered to be significant.
Authors:
Jagannathan L, Swaminathan K, Kumar SM, Kumar GR, Dey A
QTL associated with autoimmune susceptibility in C57BL/6J and BALB/c 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (27796090)
QTL associated with cystic fibrosis lung disease 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (10055276)
QTL associated with circulating hormone level QTL 8. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (25502885)
Authors:
Harper JM, Galecki AT, Burke DT, Pinkosky SL, Miller RA
QTL associated with circadian photosensitivity 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (12172308)
Authors:
Yoshimura T, Yokota Y, Ishikawa A, Yasuo S, Hayashi N, Suzuki T, Okabayashi N, Namikawa T, Ebihara S
QTL associated with male hybrid sterility QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (27796090)
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