Hippocampus Gene Expression Correlates for HOTPLATE_MEANOF2 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The HOTPLATE_MEANOF2 measures Thermal Nociception Hot Plate Avg of 2Trials under the domain Pain. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for OF_HAB_RATIO measured in BXD RI Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The OF_HAB_RATIO measures Open Field - Habituation ratio (First:Last intervals) under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Neocortex Gene Expression Correlates for ADRE_LEFT_WT measured in BXD RI Females obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The ADRE_LEFT_WT measures Left adrenal weight under the domain Adrenals. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for alcohol preference locus on Chr16 at D16Xrf580 (59.71 Mbp , Build 37)
Description:
alcohol preference locus spans 34.71 - 84.71 Mbp (NCBI Build 37) on Chr16. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for differences in cocaine responsiveness on Chr16 at Pmv-35 (67.79 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 42.79 - 92.79 Mbp (NCBI Build 37) on Chr16. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Acute cocaine - A-FOS mouse vs. Littermate control
Description:
Acute cocaine - A-FOS mouse vs. Littermate control DNA microarray Change in gene expression Animals received a single injection of cocaine (30 mg / kg intraperitoneal) and the striatum harvested at 24 hours. Avadis Microarray analysis software; standard unpaired T-test. A p < 0.001 was used as a cutoff for the selection of genes. Genes are considered up or down regulated if their expression changed 1.4 fold relative to basal conditions. (NIF Table ID 334 [184])
Authors:
Paletzki RF, Myakishev MV, Polesskaya O, Orosz A, Hyman SE, Vinson C
Genes associated with Homo sapiens that interact with the MeSH term 'Dexamethasone' (D003907). Incorporates data from 14 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Equus caballus that interact with the MeSH term 'Castor Oil' (D002368). Incorporates data from 887 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Atrazine' (D001280). Incorporates data from 48 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'trichostatin A' (C012589). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Folsomia candida that interact with the MeSH term 'phenanthrene' (C031181). Incorporates data from 22 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Grape Seed Proanthocyanidins' (C511402). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Quercetin' (D011794). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Catechin' (D002392). Incorporates data from 12 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Isotretinoin' (D015474). Incorporates data from 38 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Lewis rats operantly self-administer drugs of abuse including nicotine, whereas Fisher self-administer poorly. Lewis vs Fischer Ratio shown. Laser capture microdissection was used to obtain nucleus accumbens shell GABA neurons project to ventral pallidum labeled by Fluorogold. The gene expression profiles of these neurons were obtained using Affymetrix Rat Gene ST 1.0 microarrays. A total of 322 genes were differentially expressed at a Lewis vs Fisher ratio of >1.5-fold (P < 0.05 and FDR < 5%).
Authors:
Sharp BM, Chen H, Gong S, Wu X, Liu Z, Hiler K, Taylor WL, Matta SG
Ethanol Induced Hypothermia Chr# 16 rs4182243(46052770) with right flanking marker rs4165065(17412172) and left marker rs4200124(70695141). This was mapped in 300 + (b6x129)F2 mice.
QTL associated with cocaine induced activation 12. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (76817838)
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