List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Psoriasis vulgaris. The EFO term psoriasis vulgaris was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das, HM Kang, E Ellinghaus, V Chandran, K Callis-Duffin, R Ike, Y Li, X Wen, C Enerbäck, JE Gudjonsson, S Kõks, K Kingo, T Esko, U Mrowietz, A Reis, HE Wichmann, C Gieger, P Hoffmann, MM Nöthen, J Winkelmann, M Kunz, EG Moreta, PJ Mease, CT Ritchlin, AM Bowcock, GG Krueger, HW Lim, S Weidinger, M Weichenthal, JJ Voorhees, P Rahman, PK Gregersen, A Franke, DD Gladman, GR Abecasis, JT Elder
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Psoriasis. The EFO term psoriasis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
PE Stuart, RP Nair, E Ellinghaus, J Ding, T Tejasvi, JE Gudjonsson, Y Li, S Weidinger, B Eberlein, C Gieger, HE Wichmann, M Kunz, R Ike, GG Krueger, AM Bowcock, U Mrowietz, HW Lim, JJ Voorhees, GR Abecasis, M Weichenthal, A Franke, P Rahman, DD Gladman, JT Elder
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Psoriasis. The EFO term psoriasis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Strange, F Capon, CC Spencer, J Knight, ME Weale, MH Allen, A Barton, G Band, C Bellenguez, JG Bergboer, JM Blackwell, E Bramon, SJ Bumpstead, JP Casas, MJ Cork, A Corvin, P Deloukas, A Dilthey, A Duncanson, S Edkins, X Estivill, O Fitzgerald, C Freeman, E Giardina, E Gray, A Hofer, U Hüffmeier, SE Hunt, AD Irvine, J Jankowski, B Kirby, C Langford, J Lascorz, J Leman, S Leslie, L Mallbris, HS Markus, CG Mathew, WH McLean, R McManus, R Mössner, L Moutsianas, AT Naluai, FO Nestle, G Novelli, A Onoufriadis, CN Palmer, C Perricone, M Pirinen, R Plomin, SC Potter, RM Pujol, A Rautanen, E Riveira-Munoz, AW Ryan, W Salmhofer, L Samuelsson, SJ Sawcer, J Schalkwijk, CH Smith, M Ståhle, Z Su, R Tazi-Ahnini, H Traupe, AC Viswanathan, RB Warren, W Weger, K Wolk, N Wood, J Worthington, HS Young, PL Zeeuwen, A Hayday, AD Burden, CE Griffiths, J Kere, A Reis, G McVean, DM Evans, MA Brown, JN Barker, L Peltonen, P Donnelly, RC Trembath
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Cutaneous psoriasis. The EFO term cutaneous psoriasis measurement, psoriasis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das, HM Kang, E Ellinghaus, V Chandran, K Callis-Duffin, R Ike, Y Li, X Wen, C Enerbäck, JE Gudjonsson, S Kõks, K Kingo, T Esko, U Mrowietz, A Reis, HE Wichmann, C Gieger, P Hoffmann, MM Nöthen, J Winkelmann, M Kunz, EG Moreta, PJ Mease, CT Ritchlin, AM Bowcock, GG Krueger, HW Lim, S Weidinger, M Weichenthal, JJ Voorhees, P Rahman, PK Gregersen, A Franke, DD Gladman, GR Abecasis, JT Elder
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Psoriatic arthritis. The EFO term psoriatic arthritis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das, HM Kang, E Ellinghaus, V Chandran, K Callis-Duffin, R Ike, Y Li, X Wen, C Enerbäck, JE Gudjonsson, S Kõks, K Kingo, T Esko, U Mrowietz, A Reis, HE Wichmann, C Gieger, P Hoffmann, MM Nöthen, J Winkelmann, M Kunz, EG Moreta, PJ Mease, CT Ritchlin, AM Bowcock, GG Krueger, HW Lim, S Weidinger, M Weichenthal, JJ Voorhees, P Rahman, PK Gregersen, A Franke, DD Gladman, GR Abecasis, JT Elder
This gene set comprises 399 genes that are differentially expressed within each of five brain regions (amygdale, hippocampus, nucleus accumbens, prefrontal cortex and ventral tegmental area) when chronic nicotine treatment is administered to C3H/HeJ mice only. Background: Studies involving use of chronic nicotine treatment identify unique nicotine addiction genes and the biological processes they control in B6 and C3 mice. Results are obtained using gene expression profiling and gene ontology.
Authors:
Wang J, Gutala R, Hwang YY, Kim JM, Konu O, Ma JZ, Li MD
This gene set comprises 15 genes that are downregulated within each of three overrepresented brain regions (nucleus accumbens (NA), prefrontal cortex (PFC) and ventral tegmental area (VTA)) when chronic nicotine treatment is administered to C3H/HeJ mice only. Background: Studies involving use of chronic nicotine treatment identify unique nicotine addiction genes and the biological processes they mediate in C3H/HeJ and C57BL/6J mice. The entire study is done in five brain regions, amygdale (Amyg), hippocampus (HP), nucleus accumbens (NA), prefrontal cortex (PFC) and ventral tegmental area (VTA). Results are obtained using gene expression profiling via cDNA microarrays and gene ontology.
Authors:
Wang J, Gutala R, Hwang YY, Kim JM, Konu O, Ma JZ, Li MD
Two strains of inbred mice, C57BL/6J and DBA/2J, were exposed to acute dose of ethanol and following microarray expression profiles in these two strains, study identified genes that are differentially expressed during ethanol treatment. This gene set comprises 30 ethanol-dependent genes that were upregulated in C57BL/6j mice during the study.
This gene set comprises 30 ethanol-dependent genes that were upregulated in DBA/2J mice during the study. Background: Two strains of inbred mice, C57BL/6J and DBA/2J, were exposed to acute dose of ethanol and following microarray expression profiles in these two strains, study identified genes that are differentially expressed during ethanol treatment.
The nuclear accumbens (NA) and amygdale (Amyg) of inbred alcohol-preferring mice were examined for differential gene expression and it findings suggest that changes in gene expression in the ACB of iP rats are associated with the reinforcing effects of ethanol (EtOH). This gene set comprises 201 genes that were significantly expressed in the NA during the experiment.
Neocortex Gene Expression Correlates for BEC measured in BXD RI Females & Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The BEC measures blood ethanol concentration in mg/dl under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for JUMPS measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The JUMPS measures Morphine Number of Jumps under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for NEPCOUNT60 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEPCOUNT60 measures Novel environment locomotion (activity beam breaks) 45-60 min in the periphery under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Whole Brain Gene Expression Correlates for ROTAETHA_TIME measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The ROTAETHA_TIME measures Mean time on rotarod following ethanol under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for SVCOUNT15 measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The SVCOUNT15 measures Open Field rears 0-15 min post saline under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for ENTRIES_CLOSED measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The ENTRIES_CLOSED measures Number of entries into closed arms of plus maze under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for NX_ADIST_3 measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The NX_ADIST_3 measures Naloxone induced Morphine Withdrawal TOTAL vertical activity counts in 15 minutes under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for NX_ADIST_3 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The NX_ADIST_3 measures Naloxone induced Morphine Withdrawal TOTAL vertical activity counts in 15 minutes under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for PCT_ENTRIES_CLOSED measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The PCT_ENTRIES_CLOSED measures Percentage of entries into closed arms of plus maze under the domain Porsolt. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
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