List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Chronic kidney disease. The EFO term chronic kidney disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
C Pattaro, A Köttgen, A Teumer, M Garnaas, CA Böger, C Fuchsberger, M Olden, MH Chen, A Tin, D Taliun, M Li, X Gao, M Gorski, Q Yang, C Hundertmark, MC Foster, CM O'Seaghdha, N Glazer, A Isaacs, CT Liu, AV Smith, JR O'Connell, M Struchalin, T Tanaka, G Li, AD Johnson, HJ Gierman, M Feitosa, SJ Hwang, EJ Atkinson, K Lohman, MC Cornelis, Å Johansson, A Tönjes, A Dehghan, V Chouraki, EG Holliday, R Sorice, Z Kutalik, T Lehtimäki, T Esko, H Deshmukh, S Ulivi, AY Chu, F Murgia, S Trompet, M Imboden, B Kollerits, G Pistis, TB Harris, LJ Launer, T Aspelund, G Eiriksdottir, BD Mitchell, E Boerwinkle, H Schmidt, M Cavalieri, M Rao, FB Hu, A Demirkan, BA Oostra, M de Andrade, ST Turner, J Ding, JS Andrews, BI Freedman, W Koenig, T Illig, A Döring, HE Wichmann, I Kolcic, T Zemunik, M Boban, C Minelli, HE Wheeler, W Igl, G Zaboli, SH Wild, AF Wright, H Campbell, D Ellinghaus, U Nöthlings, G Jacobs, R Biffar, K Endlich, F Ernst, G Homuth, HK Kroemer, M Nauck, S Stracke, U Völker, H Völzke, P Kovacs, M Stumvoll, R Mägi, A Hofman, AG Uitterlinden, F Rivadeneira, YS Aulchenko, O Polasek, N Hastie, V Vitart, C Helmer, JJ Wang, D Ruggiero, S Bergmann, M Kähönen, J Viikari, T Nikopensius, M Province, S Ketkar, H Colhoun, A Doney, A Robino, F Giulianini, BK Krämer, L Portas, I Ford, BM Buckley, M Adam, GA Thun, B Paulweber, M Haun, C Sala, M Metzger, P Mitchell, M Ciullo, SK Kim, P Vollenweider, O Raitakari, A Metspalu, C Palmer, P Gasparini, M Pirastu, JW Jukema, NM Probst-Hensch, F Kronenberg, D Toniolo, V Gudnason, AR Shuldiner, J Coresh, R Schmidt, L Ferrucci, DS Siscovick, CM van Duijn, I Borecki, SL Kardia, Y Liu, GC Curhan, I Rudan, U Gyllensten, JF Wilson, A Franke, PP Pramstaller, R Rettig, I Prokopenko, JC Witteman, C Hayward, P Ridker, A Parsa, M Bochud, IM Heid, W Goessling, DI Chasman, WH Kao, CS Fox
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Pit-and-Fissure caries. The EFO term pit and fissure surface dental caries was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Z Zeng, E Feingold, X Wang, DE Weeks, M Lee, DT Cuenco, B Broffitt, RJ Weyant, R Crout, DW McNeil, SM Levy, ML Marazita, JR Shaffer
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Dental caries. The EFO term dental caries was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JR Shaffer, X Wang, E Feingold, M Lee, F Begum, DE Weeks, KT Cuenco, MM Barmada, SK Wendell, DR Crosslin, CC Laurie, KF Doheny, EW Pugh, Q Zhang, B Feenstra, F Geller, HA Boyd, H Zhang, M Melbye, JC Murray, RJ Weyant, R Crout, DW McNeil, SM Levy, RL Slayton, MC Willing, B Broffitt, AR Vieira, ML Marazita
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Lachrymal/Salivary gland lesion in type 1 autoimmune pancreatitis. The EFO term salivary gland lesion, autoimmune pancreatitis type 1, lachrymal gland lesion was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
T Oguchi, M Ota, T Ito, H Hamano, N Arakura, Y Katsuyama, A Meguro, S Kawa
The total transcriptome including genes that are differentially expressed in cocaine addicts compared to control subjects. Post-mortem brain samples were collected from the dorsolateral prefrontal cortex (dlPFC) of the cocaine addict group and the control group. To assess gene expression, RNA-seq was performed. Data taken from Supplementary Table 2. Values presented are k.diff values. Data available from GEO with accession number GSE99349."
Authors:
Efrain A Ribeiro, Joseph R Scarpa, Susanna P Garamszegi, Andrew Kasarskis, Deborah C Mash, Eric J Nestler
Data from GEO GSE194368 and analyzed using GEO2R, only top gene shown. Authors identified transcriptional adaptations of GR signaling in the amygdala of humans with OUD. Thus, GRs, their coregulators and downstream systems may represent viable therapeutic targets to treat the “stress side” of OUD.
Authors:
Stephanie A Carmack, Janaina C M Vendruscolo, M Adrienne McGinn, Jorge Miranda-Barrientos, Vez Repunte-Canonigo, Gabriel D Bosse, Daniele Mercatelli, Federico M Giorgi, Yu Fu, Anthony J Hinrich, Francine M Jodelka, Karen Ling, Robert O Messing, Randall T Peterson, Frank Rigo, Scott Edwards, Pietro P Sanna, Marisela Morales, Michelle L Hastings, George F Koob, Leandro F Vendruscolo
Striatum Gene Expression Correlates for NEVCOUNT15 measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEVCOUNT15 measures Novel environment vertical activity counts min 0-15 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for NOVEL_ADIST_1 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NOVEL_ADIST_1 measures Open Field Inovel TOTAL locomotion ( cm in 1 hr) in the center under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Striatum Gene Expression Correlates for NOVEL_ACOUNT_1 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NOVEL_ACOUNT_1 measures Open Field InovelTOTAL locomotion (activity beam breaks) in the center under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
These genes are a 1 class SAM significant (1% FDR) in nucleus accumbens (core + shell) for saline treated ("basal") control vs. Fyn KO mice. The list was filtered for an average Sscore >2.0 or <-2.0. Data from Farris and Miles, PLoS One, 2013.
Genes associated with Homo sapiens that interact with the MeSH term 'entinostat' (C118739). Incorporates data from 11 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Coumestrol' (D003375). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine' (C516138). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'resveratrol' (C059514). Incorporates data from 16 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Tretinoin' (D014212). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryzias latipes that interact with the MeSH term 'Estradiol' (D004958). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'panobinostat' (C496932). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Gadus morhua that interact with the MeSH term 'methylmercuric chloride' (C004925). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'arsenic trioxide' (C006632). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide' (C459179). Incorporates data from 9 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'belinostat' (C487081). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Valproic Acid' (D014635). Incorporates data from 1238 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Nickel' (D009532). Incorporates data from 166 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryzias latipes that interact with the MeSH term 'Tetrachlorodibenzodioxin' (D013749). Incorporates data from 41 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
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