Whole Brain Gene Expression Correlates for ACTI05_ETHA measured in BXD RI Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The ACTI05_ETHA measures Distance traveled (cm) during the first five minutes after ethanol under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for high-dose ethanol actions on Chr9 at D9Mit42 (21.79 Mbp , Build 37)
Description:
high-dose ethanol actions spans 0.00 - 46.79 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Erwin VG, Markel PD, Johnson TE, Gehle VM, Jones BC
QTL for METH responses for home cage activity on Chr9 at Fli-1 (30.20 Mbp , Build 37)
Description:
METH responses for home cage activity spans 5.20 - 55.20 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
BECs at LORR Recovery Chr# 9 rs13480854(7524005) with right flanking marker mCV23893269 (4062079) and left marker rs3663313 (123063108). This was mapped in 300 + (b6x129)F2 mice.
QTL associated with cystic fibrosis modifier QTL 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (32308040)
QTL associated with haloperidol-induced catelepsy 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (31167847)
QTL associated with salmonella enteritidis susceptibility 6. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (9025264)
QTL associated with systemic lupus erythmatosus suppressor 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (9107561)
Authors:
Haywood ME, Gabriel L, Rose SJ, Rogers NJ, Izui S, Morley BJ
"anomaly in the production or release of proteins secreted by vertebrate cells in response to a wide variety of inducers; they confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions" Data derived from MGI_GenePheno.rpt and the MP OBO tree dated 2016-11-07
"anomaly in the production or release of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation" Data derived from MGI_GenePheno.rpt and the MP OBO tree dated 2016-11-07
"anomaly in the production or cellular release of soluble factors which stimulate growth-related activities of leukocytes and other cell types, that can act to enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli" Data derived from MGI_GenePheno.rpt and the MP OBO tree dated 2016-11-07
"increase in the production or release of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation" Data derived from MGI_GenePheno.rpt and the MP OBO tree dated 2016-11-07
"the observable morphological, physiological, behavioral and other characteristics of mammalian organisms that are manifested through development and lifespan" Data derived from MGI_GenePheno.rpt and the MP OBO tree dated 2016-11-07
"deviation from the expected number of abnormal growths in a specific population" Data derived from MGI_GenePheno.rpt and the MP OBO tree dated 2016-11-07
"anomaly in the production or cellular release of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells" Data derived from MGI_GenePheno.rpt and the MP OBO tree dated 2016-11-07
"increase in the production or release of an interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form; both membrane-bound and secreted forms of interleukin-1alpha are biologically active" Data derived from MGI_GenePheno.rpt and the MP OBO tree dated 2016-11-07
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