Tier
Species
Size
Attr.
GeneSet
Tier III
26322
GS407879: Genes differentially expressed with Fentanyl in C57BL/6 J and A/J in nucleus accumbens by stain_qvalue
Figure Label:
Fentanyl_C57BL/6 J _A/J_nucleus accumbens_byStain_qvalue
Description:
The current study used two inbred mouse strains, C57BL/6 J and A/J, to investigate the genetics of behavioral responses to fentanyl. Mice were tested for conditioned place preference and fentanyl-induced locomotor activity. C57BL/6J mice formed a conditioned place preference to fentanyl injections and fentanyl increased their activity. Neither effect was noted in A/J mice. We conducted RNA-sequencing on the nucleus accumbens of mice used for fentanyl-induced locomotor activity. Surprisingly, we noted few differentially expressed genes using treatment as the main factor. However many genes differed between strains.
Authors:
Samuel J Harp, Mariangela Martini, Will Rosenow, Larry D Mesner, Hugh Johnson, Charles R Farber, Emilie F Rissman
Tier IV
19215
GS406229: cc coca diffcoexp universe
Figure Label:
cc coca diffcoexp universe
Description:
cc coca diffcoexp universe
Authors:
None
Tier IV
51914
GS405734: WWP1 KO vs WT
Figure Label:
WWP1
Description:
To see gene sets category
Authors:
Tier II
2141
GS223060: Kidney mass QTL 18 (Kidm18 Published QTL Chr 1)
Figure Label:
QTL-Kidm18-Rat-Chr 1
Description:
QTL Associated with Kidney mass. On Chromosome 1 with a LOD score= 5.7, p-value =. From a(n) intercross of
Authors:
Bilusic M, Bataillard A, Tschannen MR, Gao L, Barreto NE, Vincent M, Wang T, Jacob HJ, Sassard J, Kwitek AE
Tier II
2294
GS223151: Blood pressure QTL 362 (Bp362 Published QTL Chr 1)
Figure Label:
QTL-Bp362-Rat-Chr 1
Description:
QTL Associated with Blood pressure. On Chromosome 1 with a LOD score= , p-value =0.001. From a(n) of
Authors:
Chauvet C, Crespo K, Ménard A, Roy J, Deng AY
Tier II
2331
GS223338: Mammary carcinoma susceptibility QTL 32 (Mcs32 Published QTL Chr 1)
Figure Label:
QTL-Mcs32-Rat-Chr 1
Description:
QTL Associated with Mammary tumor susceptibility. On Chromosome 1 with a LOD score= 2.61, p-value =. From a(n) intercross of
Authors:
Herrera VL, Ponce LR, Ruiz-Opazo N
Tier II
2173
GS223347: Hepatocarcinoma resistance QTL 15 (Hcar15 Published QTL Chr 1)
Figure Label:
QTL-Hcar15-Rat-Chr 1
Description:
QTL Associated with subcutaneous adipose mass. On Chromosome 17 with a LOD score= 8.62, p-value =0.001. From a(n) intercross of QTL Associated with Liver tumor resistance. On Chromosome 1 with a LOD score= , p-value =0.05. From a(n) of
Authors:
Liu H, Higashi K, Hiai H
Tier II
2084
GS223773: Proteinuria QTL 4 (Pur4 Published QTL Chr 1)
Figure Label:
QTL-Pur4-Rat-Chr 1
Description:
QTL Associated with Renal function. On Chromosome 1 with a LOD score= 3.3, p-value =0.003. From a(n) of
Authors:
Garrett MR, Joe B, Yerga-Woolwine S
Tier II
2024
GS223828: Serum corticosterone level QTL 1 (Scort1 Published QTL Chr 1)
Figure Label:
QTL-Scort1-Rat-Chr 1
Description:
QTL Associated with Hormone level. On Chromosome 1 with a LOD score= 3.4, p-value =. From a(n) intercross of
Authors:
Bilusic M, Bataillard A, Tschannen MR, Gao L, Barreto NE, Vincent M, Wang T, Jacob HJ, Sassard J, Kwitek AE
Tier II
2084
GS223847: Urinary albumin excretion QTL 30 (Uae30 Published QTL Chr 1)
Figure Label:
QTL-Uae30-Rat-Chr 1
Description:
QTL Associated with Renal function. On Chromosome 1 with a LOD score= 3.3, p-value =0.003. From a(n) of
Authors:
Garrett MR, Joe B, Yerga-Woolwine S
Tier II
2084
GS224023: Urinary albumin excretion QTL 5 (Uae5 Published QTL Chr 1)
Figure Label:
QTL-Uae5-Rat-Chr 1
Description:
QTL Associated with Renal function. On Chromosome 1 with a LOD score= 4, p-value =. From a(n) intercross of SS/JrMcoxSHR/NHsd
Authors:
Garrett MR, Dene H, Rapp JP
Tier II
2141
GS224263: Body weight QTL 34 (Bw34 Published QTL Chr 1)
Figure Label:
QTL-Bw34-Rat-Chr 1
Description:
QTL Associated with Body weight. On Chromosome 1 with a LOD score= 4.1, p-value =. From a(n) intercross of
Authors:
Bilusic M, Bataillard A, Tschannen MR, Gao L, Barreto NE, Vincent M, Wang T, Jacob HJ, Sassard J, Kwitek AE
Tier II
2141
GS224269: Body weight QTL 33 (Bw33 Published QTL Chr 1)
Figure Label:
QTL-Bw33-Rat-Chr 1
Description:
QTL Associated with Body weight. On Chromosome 1 with a LOD score= 5.2, p-value =. From a(n) intercross of
Authors:
Bilusic M, Bataillard A, Tschannen MR, Gao L, Barreto NE, Vincent M, Wang T, Jacob HJ, Sassard J, Kwitek AE
Tier II
2123
GS224404: Insulin level QTL 11 (Insul11 Published QTL Chr 1)
Figure Label:
QTL-Insul11-Rat-Chr 1
Description:
QTL Associated with Insulin level. On Chromosome 1 with a LOD score= 4, p-value =. From a(n) intercross of QTL Associated with Insulin level. On Chromosome 1 with a LOD score= 3.25, p-value =. From a(n) intercross of
Authors:
Tier IV
2968
GS406005: Q-values for down differentially expressed genes in the central nucleus of the amygdala between B6 and CAST
Figure Label:
Down DEGs CeA B6-CAST
Description:
Genes identified as expressed lower (down) in the AJ strain than in the CAST strain. Differentially expressed genes had a Q-value < 0.05 following the Benjamini-Hochberg methodology for false discovery rates in the limma+voom pipeline within edgeR. Q-value is reported from the topTable function.
Authors:
Tier IV
2968
GS406025: Q-values for down differentially expressed genes in the central nucleus of the amygdala between B6 and CAST
Figure Label:
Down DEGs CeA B6-CAST
Description:
Genes identified as expressed lower (down) in the AJ strain than in the CAST strain. Differentially expressed genes had a Q-value < 0.05 following the Benjamini-Hochberg methodology for false discovery rates in the limma+voom pipeline within edgeR. Q-value is reported from the topTable function.
Authors:
Tier III
12627
GS407727: Microglia control escalation of drinking in alcohol dependent mice: Genomic and synaptic drivers, main effect Microglia depletion
Figure Label:
Alcohol_medial_prefrontal_cortex_logFC
Description:
We investigated the role of microglia in a mouse model of alcohol dependence using a colony stimulating factor 1 receptor inhibitor (PLX5622) to deplete microglia and a chronic intermittent ethanol vapor two-bottle choice drinking procedure. Additionally, we examined anxiety-like behavior during withdrawal. We then analyzed synaptic neuroadaptations in the central nucleus of the amygdala (CeA) and gene expression changes in the medial prefrontal cortex (mPFC) and CeA from the same animals used for behavioral studies.
Authors:
Tier IV
5770
GS408303: Genes differentially expressed with Fentanyl in C57BL/6 J and A/J in nucleus accumbens by stain_qvalue_0.05subset
Figure Label:
Fentanyl_C57BL/6 J _A/J_nucleus accumbens_byStain_qvalue_subset
Description:
Subset dataset of differentially expressed genes at padj < 0.05 of GS407879.
Authors:
Samuel J Harp, Mariangela Martini, Will Rosenow, Larry D Mesner, Hugh Johnson, Charles R Farber, Emilie F Rissman
Tier II
1534
GS223043: Hepatocarcinoma susceptibility QTL 5 (Hcas5 Published QTL Chr 1)
Figure Label:
QTL-Hcas5-Rat-Chr 1
Description:
QTL Associated with Liver tumor susceptibility. On Chromosome 1 with a LOD score= 3.12, p-value =. From a(n) intercross of
Authors:
De Miglio MR, Pascale RM, Simile MM, Muroni MR, Virdis P, Kwong KM, Wong LK, Bosinco GM, Pulina FR, Calvisi DF, Frau M, Wood GA, Archer MC, Feo F
Tier II
972
GS223258: Glomerulus QTL 18 (Glom18 Published QTL Chr 1)
Figure Label:
QTL-Glom18-Rat-Chr 1
Description:
QTL Associated with Renal pathology. On Chromosome 1 with a LOD score= 2.4, p-value =0.003. From a(n) backcross of
Authors:
Ijpelaar DH, Schulz A, Aben J, van der Wal A, Bruijn JA, Kreutz R, de Heer E
Tier II
910
GS223567: Epididymal fat weight QTL 5 (Epfw5 Published QTL Chr 1)
Figure Label:
QTL-Epfw5-Rat-Chr 1
Description:
QTL Associated with epididymal fat pad mass. On Chromosome 1 with a LOD score= 4.4, p-value =. From a(n) intercross of
Authors:
Yamamoto T, Izumi-Yamamoto K, Iizuka Y, Shirota M, Nagase M, Fujita T, Gotoda T
Tier II
1146
GS223625: Age-related retinal degeneration QTL 3 (Arrd3 Published QTL Chr 1)
Figure Label:
QTL-Arrd3-Rat-Chr 1
Description:
QTL Associated with retinal layer morphology trait. On Chromosome 1 with a LOD score= 3.07, p-value =. From a(n) intercross of
Authors:
Korbolina EE, Kozhevnikova OS, Stefanova NA, Kolosova NG
Tier II
1135
GS223792: Blood pressure QTL 255 (Bp255 Published QTL Chr 1)
Figure Label:
QTL-Bp255-Rat-Chr 1
Description:
QTL Associated with Blood pressure. On Chromosome 1 with a LOD score= 3.6, p-value =. From a(n) of
Authors:
Ueno T, Tremblay J, Kunes J, Zicha J, Dobesova Z, Pausova Z, Deng AY, Sun YL, Jacob HJ, Hamet P
Tier II
1500
GS224506: Cardiac mass QTL35 (Cm35 Published QTL Chr 1)
Figure Label:
QTL-Cm35-Rat-Chr 1
Description:
QTL Associated with Cardiac mass. On Chromosome 1 with a LOD score= 5.7, p-value =. From a(n) intercross of
Authors:
Bilusic M, Bataillard A, Tschannen MR, Gao L, Barreto NE, Vincent M, Wang T, Jacob HJ, Sassard J, Kwitek AE
Tier II
1064
GS224577: Estrogen-induced pituitary tumorigenesis QTL 10 (Ept10 Published QTL Chr 1)
Figure Label:
QTL-Ept10-Rat-Chr 1
Description:
QTL Associated with Gland mass. On Chromosome 1 with a LOD score= 3.8, p-value =. From a(n) of
Authors:
Strecker TE, Spady TJ, Schaffer BS, Gould KA, Kaufman AE, Shen F, McLaughlin MT, Pennington KL, Meza JL, Shull JD
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