List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Blood pressure. The EFO term mean arterial pressure was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
LV Wain, GC Verwoert, PF O'Reilly, G Shi, T Johnson, AD Johnson, M Bochud, KM Rice, P Henneman, AV Smith, GB Ehret, N Amin, MG Larson, V Mooser, D Hadley, M Dörr, JC Bis, T Aspelund, T Esko, AC Janssens, JH Zhao, S Heath, M Laan, J Fu, G Pistis, J Luan, P Arora, G Lucas, N Pirastu, I Pichler, AU Jackson, RJ Webster, F Zhang, JF Peden, H Schmidt, T Tanaka, H Campbell, W Igl, Y Milaneschi, JJ Hottenga, V Vitart, DI Chasman, S Trompet, JL Bragg-Gresham, BZ Alizadeh, JC Chambers, X Guo, T Lehtimäki, B Kühnel, LM Lopez, O Polašek, M Boban, CP Nelson, AC Morrison, V Pihur, SK Ganesh, A Hofman, S Kundu, FU Mattace-Raso, F Rivadeneira, EJ Sijbrands, AG Uitterlinden, SJ Hwang, RS Vasan, TJ Wang, S Bergmann, P Vollenweider, G Waeber, J Laitinen, A Pouta, P Zitting, WL McArdle, HK Kroemer, U Völker, H Völzke, NL Glazer, KD Taylor, TB Harris, H Alavere, T Haller, A Keis, ML Tammesoo, Y Aulchenko, I Barroso, KT Khaw, P Galan, S Hercberg, M Lathrop, S Eyheramendy, E Org, S Sõber, X Lu, IM Nolte, BW Penninx, T Corre, C Masciullo, C Sala, L Groop, BF Voight, O Melander, CJ O'Donnell, V Salomaa, AP d'Adamo, A Fabretto, F Faletra, S Ulivi, F Del Greco, M Facheris, FS Collins, RN Bergman, JP Beilby, J Hung, AW Musk, M Mangino, SY Shin, N Soranzo, H Watkins, A Goel, A Hamsten, P Gider, M Loitfelder, M Zeginigg, D Hernandez, SS Najjar, P Navarro, SH Wild, AM Corsi, A Singleton, EJ de Geus, G Willemsen, AN Parker, LM Rose, B Buckley, D Stott, M Orru, M Uda, MM van der Klauw, W Zhang, X Li, J Scott, YD Chen, GL Burke, M Kähönen, J Viikari, A Döring, T Meitinger, G Davies, JM Starr, V Emilsson, A Plump, JH Lindeman, PA Hoen, IR König, JF Felix, R Clarke, JC Hopewell, H Ongen, M Breteler, S Debette, AL Destefano, M Fornage, GF Mitchell, NL Smith, H Holm, K Stefansson, G Thorleifsson, U Thorsteinsdottir, NJ Samani, M Preuss, I Rudan, C Hayward, IJ Deary, HE Wichmann, OT Raitakari, W Palmas, JS Kooner, RP Stolk, JW Jukema, AF Wright, DI Boomsma, S Bandinelli, UB Gyllensten, JF Wilson, L Ferrucci, R Schmidt, M Farrall, TD Spector, LJ Palmer, J Tuomilehto, A Pfeufer, P Gasparini, D Siscovick, D Altshuler, RJ Loos, D Toniolo, H Snieder, C Gieger, P Meneton, NJ Wareham, BA Oostra, A Metspalu, L Launer, R Rettig, DP Strachan, JS Beckmann, JC Witteman, J Erdmann, KW van Dijk, E Boerwinkle, M Boehnke, PM Ridker, MR Jarvelin, A Chakravarti, GR Abecasis, V Gudnason, C Newton-Cheh, D Levy, PB Munroe, BM Psaty, MJ Caulfield, DC Rao, MD Tobin, P Elliott, CM van Duijn
Hippocampus Gene Expression Correlates for LM_CUE_ACTIVITY measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The LM_CUE_ACTIVITY measures Activity in altered context during presentation of cue under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for LM_CUE_ACTIVITY measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The LM_CUE_ACTIVITY measures Activity in altered context during presentation of cue under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Neocortex Gene Expression Correlates for LM_CUE_SUPPRESS measured in BXD RI Females obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The LM_CUE_SUPPRESS measures Suppression of activity in altered context under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for LM_ALT_CONTEXT measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The LM_ALT_CONTEXT measures Activity in altered context in fear conditioning apparatus under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for LM_ALT_CONTEXT measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The LM_ALT_CONTEXT measures Activity in altered context in fear conditioning apparatus under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for MDMA_ACT_SAL_1 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The MDMA_ACT_SAL_1 measures Locomotor activity of mice on Day 1 under the domain MDMA. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Neocortex Gene Expression Correlates for SALIVA measured in BXD RI Females & Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The SALIVA measures Morphine - Salivation under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Neocortex Gene Expression Correlates for SALIVA measured in BXD RI Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The SALIVA measures Morphine - Salivation under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
from Lewohl et al., 2000; from case group one (identical to case group used in PCR-differential display experiments reported by Fan et al., 1999); includes three uncomplicated alcoholics, one alcoholic with cirrhosis, and one alcoholic with concomitant Wernicke encephalopathy
Authors:
Lewohl JM, Wang L, Miles MF, Zhang L, Dodd PR, Harris RA
cocaine related behavior 10 (Cocrb10) spans 93.149752 - 143.149752 Mbp (NCBI Build 37) on Chr 9. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
QTL for ethanol withdrawal on Chr9 at D9Ncvs40 (85.16 Mbp , Build 37)
Description:
ethanol withdrawal spans 60.16 - 110.16 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for home cage activity on Chr9 at Gst2-3 (90.12 Mbp , Build 37)
Description:
METH responses for home cage activity spans 65.12 - 115.12 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for differences in cocaine responsiveness on Chr9 at D9M!t12 (94.40 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 69.40 - 119.40 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr9 at D9Mit12 (103.09 Mbp , Build 37)
Description:
METH responses for body temperature spans 78.09 - 128.09 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
alcohol response 4 (a.k.a. high-dose ethanol actions) is associated with neurotensin immunoreactivity and sleep time after alcohol administration mapped to 55 cM on mouse Chromosome 9 near D9Mit12 (P=0.0006). This locus is named Alcrsp4 (alcohol response 4). Potential candidate genes found in this region are Chrna3 and Gnai2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Erwin VG, Markel PD, Johnson TE, Gehle VM, Jones BC
QTL for differences in cocaine responsiveness on Chr9 at D9MIt2O (105.59 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 80.59 - 130.59 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for cocaine seizure on Chr9 at D9Mit51 (111.26 Mbp , Build 37)
Description:
cocaine seizure spans 86.26 - 136.26 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for home cage activity on Chr9 at D9Ncvs17 (114.61 Mbp , Build 37)
Description:
METH responses for home cage activity spans 89.61 - 139.61 Mbp (NCBI Build 37) on Chr9. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
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