List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Body mass index. The EFO term body mass index was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
KL Monda, GK Chen, KC Taylor, C Palmer, TL Edwards, LA Lange, MC Ng, AA Adeyemo, MA Allison, LF Bielak, G Chen, M Graff, MR Irvin, SK Rhie, G Li, Y Liu, Y Liu, Y Lu, MA Nalls, YV Sun, MK Wojczynski, LR Yanek, MC Aldrich, A Ademola, CI Amos, EV Bandera, CH Bock, A Britton, U Broeckel, Q Cai, NE Caporaso, CS Carlson, J Carpten, G Casey, WM Chen, F Chen, YD Chen, CW Chiang, GA Coetzee, E Demerath, SL Deming-Halverson, RW Driver, P Dubbert, MF Feitosa, Y Feng, BI Freedman, EM Gillanders, O Gottesman, X Guo, T Haritunians, T Harris, CC Harris, AJ Hennis, DG Hernandez, LH McNeill, TD Howard, BV Howard, VJ Howard, KC Johnson, SJ Kang, BJ Keating, S Kolb, LH Kuller, A Kutlar, CD Langefeld, G Lettre, K Lohman, V Lotay, H Lyon, JE Manson, W Maixner, YA Meng, KR Monroe, I Morhason-Bello, AB Murphy, JC Mychaleckyj, R Nadukuru, KL Nathanson, U Nayak, A N'diaye, B Nemesure, SY Wu, MC Leske, C Neslund-Dudas, M Neuhouser, S Nyante, H Ochs-Balcom, A Ogunniyi, TO Ogundiran, O Ojengbede, OI Olopade, JR Palmer, EA Ruiz-Narvaez, ND Palmer, MF Press, E Rampersaud, LJ Rasmussen-Torvik, JL Rodriguez-Gil, B Salako, EE Schadt, AG Schwartz, DA Shriner, D Siscovick, SB Smith, S Wassertheil-Smoller, EK Speliotes, MR Spitz, L Sucheston, H Taylor, BO Tayo, MA Tucker, DJ Van Den Berg, DR Edwards, Z Wang, JK Wiencke, TW Winkler, JS Witte, M Wrensch, X Wu, JJ Yang, AM Levin, TR Young, NA Zakai, M Cushman, KA Zanetti, JH Zhao, W Zhao, Y Zheng, J Zhou, RG Ziegler, JM Zmuda, JK Fernandes, GS Gilkeson, DL Kamen, KJ Hunt, IJ Spruill, CB Ambrosone, S Ambs, DK Arnett, L Atwood, DM Becker, SI Berndt, L Bernstein, WJ Blot, IB Borecki, EP Bottinger, DW Bowden, G Burke, SJ Chanock, RS Cooper, J Ding, D Duggan, MK Evans, C Fox, WT Garvey, JP Bradfield, H Hakonarson, SF Grant, A Hsing, L Chu, JJ Hu, D Huo, SA Ingles, EM John, JM Jordan, EK Kabagambe, SL Kardia, RA Kittles, PJ Goodman, EA Klein, LN Kolonel, L Le Marchand, S Liu, B McKnight, RC Millikan, TH Mosley, B Padhukasahasram, LK Williams, SR Patel, U Peters, CA Pettaway, PA Peyser, BM Psaty, S Redline, CN Rotimi, BA Rybicki, MM Sale, PJ Schreiner, LB Signorello, AB Singleton, JL Stanford, SS Strom, MJ Thun, M Vitolins, W Zheng, JH Moore, SM Williams, S Ketkar, X Zhu, AB Zonderman, C Kooperberg, GJ Papanicolaou, BE Henderson, AP Reiner, JN Hirschhorn, RJ Loos, KE North, CA Haiman
Striatum Gene Expression Correlates for COCA_BASE_DRUG measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The COCA_BASE_DRUG measures CPP - Time (s) in drug-paired compartment a under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for VERCNT15 measured in BXD RI Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The VERCNT15 measures Morphine vertical activity counts minutes 0-15 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for VERCNT30 measured in BXD RI Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The VERCNT30 measures Morphine vertical activity counts minutes 15-30 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for METH responses for climbing on Chr4 at Mltr3 (34.50 Mbp , Build 37)
Description:
METH responses for climbing spans 9.50 - 59.50 Mbp (NCBI Build 37) on Chr4. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr4 at D4Nds8 (40.90 Mbp , Build 37)
Description:
METH responses for body temperature spans 15.90 - 65.90 Mbp (NCBI Build 37) on Chr4. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for chewing on Chr4 at Lyb4 (46.47 Mbp , Build 37)
Description:
METH responses for chewing spans 21.47 - 71.47 Mbp (NCBI Build 37) on Chr4. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'Arsenic' (D001151). Incorporates data from 87 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Aflatoxin B1' (D016604). Incorporates data from 5 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'arsenic trioxide' (C006632). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Benzo(a)pyrene' (D001564). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Average rotarod training latency Chr# 4 rs13477617(26886337) with right flanking marker rs3660863(7127435) and left marker rs3684104 (38269953). This was mapped in 300 + (b6x129)F2 mice.
QTL associated with "alcohol preference locus 7, male specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (34342409)
QTL associated with "alcohol preference locus 8, female specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (34342409)
QTL associated with angiogenesis due to FGF2 QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (32254939)
QTL associated with autoimmune renal vasculitis 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (46345518)
Authors:
Qu WM, Miyazaki T, Terada M, Lu LM, Nishihara M, Yamada A, Mori S, Nakamura Y, Ogasawara H, Yazawa C, Nakatsuru S, Nose M
QTL associated with ethanol induced low dose activation 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (46345518)
QTL associated with keratinocyte stem cell locus 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (9322672)
Authors:
Popova NV, Morris RJ
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