List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Pulmonary function (interaction). The EFO term forced expiratory volume was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
DB Hancock, M Soler Artigas, SA Gharib, A Henry, A Manichaikul, A Ramasamy, DW Loth, M Imboden, B Koch, WL McArdle, AV Smith, J Smolonska, A Sood, W Tang, JB Wilk, G Zhai, JH Zhao, H Aschard, KM Burkart, I Curjuric, M Eijgelsheim, P Elliott, X Gu, TB Harris, C Janson, G Homuth, PG Hysi, JZ Liu, LR Loehr, K Lohman, RJ Loos, AK Manning, KD Marciante, M Obeidat, DS Postma, MC Aldrich, GG Brusselle, TH Chen, G Eiriksdottir, N Franceschini, J Heinrich, JI Rotter, C Wijmenga, OD Williams, AR Bentley, A Hofman, CC Laurie, T Lumley, AC Morrison, BR Joubert, F Rivadeneira, DJ Couper, SB Kritchevsky, Y Liu, M Wjst, LV Wain, JM Vonk, AG Uitterlinden, T Rochat, SS Rich, BM Psaty, GT O'Connor, KE North, DB Mirel, B Meibohm, LJ Launer, KT Khaw, AL Hartikainen, CJ Hammond, S Gläser, J Marchini, P Kraft, NJ Wareham, H Völzke, BH Stricker, TD Spector, NM Probst-Hensch, D Jarvis, MR Jarvelin, SR Heckbert, V Gudnason, HM Boezen, RG Barr, PA Cassano, DP Strachan, M Fornage, IP Hall, J Dupuis, MD Tobin, SJ London
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1). The EFO term FEV change measurement, response to bronchodilator, chronic obstructive pulmonary disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Hardin, MH Cho, ML McDonald, E Wan, DA Lomas, HO Coxson, W MacNee, J Vestbo, JC Yates, A Agusti, PM Calverley, B Celli, C Crim, S Rennard, E Wouters, P Bakke, SP Bhatt, V Kim, J Ramsdell, EA Regan, BJ Make, JE Hokanson, JD Crapo, TH Beaty, CP Hersh
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Thyrotoxic hypokalemic periodic paralysis. The EFO term Thyrotoxic periodic paralysis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
CL Cheung, KS Lau, AY Ho, KK Lee, SC Tiu, EY Lau, J Leung, MW Tsang, KW Chan, CY Yeung, YC Woo, EY Cheung, VH Hung, HK Pang, CS Hung, PC Sham, AW Kung
Twelve known genes were found to be differentially regulated in the CD inflamed smokers group versus the CD inflamed never-smokers group (Table 2). However, only six genes had fold changes higher than 1.5, which was chosen as the minimal fold change relevant to report. The expression of these six genes and their potential association with gender and age were tested (linear regression analysis) without any significant correlations.
Authors:
Nielsen OH, Bjerrum JT, Csillag C, Nielsen FC, Olsen J
A form of inherited long QT syndrome (or LQT7) that is characterized by a triad of potassium-sensitive periodic paralysis, VENTRICULAR ECTOPIC BEATS, and abnormal features such as short stature, low-set ears, and SCOLIOSIS. It results from mutations of KCNJ2 gene which encodes a channel protein (INWARD RECTIFIER POTASSIUM CHANNELS) that regulates resting membrane potential.
Generated by gene2mesh v. 1.1.1
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Forced vital capacity. The EFO term vital capacity was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
DW Loth, M Soler Artigas, SA Gharib, LV Wain, N Franceschini, B Koch, TD Pottinger, AV Smith, Q Duan, C Oldmeadow, MK Lee, DP Strachan, AL James, JE Huffman, V Vitart, A Ramasamy, NJ Wareham, J Kaprio, XQ Wang, H Trochet, M Kähönen, C Flexeder, E Albrecht, LM Lopez, K de Jong, B Thyagarajan, AC Alves, S Enroth, E Omenaas, PK Joshi, T Fall, A Viñuela, LJ Launer, LR Loehr, M Fornage, G Li, JB Wilk, W Tang, A Manichaikul, L Lahousse, TB Harris, KE North, AR Rudnicka, J Hui, X Gu, T Lumley, AF Wright, ND Hastie, S Campbell, R Kumar, I Pin, RA Scott, KH Pietiläinen, I Surakka, Y Liu, EG Holliday, H Schulz, J Heinrich, G Davies, JM Vonk, M Wojczynski, A Pouta, A Johansson, SH Wild, E Ingelsson, F Rivadeneira, H Völzke, PG Hysi, G Eiriksdottir, AC Morrison, JI Rotter, W Gao, DS Postma, WB White, SS Rich, A Hofman, T Aspelund, D Couper, LJ Smith, BM Psaty, K Lohman, EG Burchard, AG Uitterlinden, M Garcia, BR Joubert, WL McArdle, AB Musk, N Hansel, SR Heckbert, L Zgaga, JB van Meurs, P Navarro, I Rudan, YM Oh, S Redline, DL Jarvis, JH Zhao, T Rantanen, GT O'Connor, S Ripatti, RJ Scott, S Karrasch, H Grallert, NC Gaddis, JM Starr, C Wijmenga, RL Minster, DJ Lederer, J Pekkanen, U Gyllensten, H Campbell, AP Morris, S Gläser, CJ Hammond, KM Burkart, J Beilby, SB Kritchevsky, V Gudnason, DB Hancock, OD Williams, O Polasek, T Zemunik, I Kolcic, MF Petrini, M Wjst, WJ Kim, DJ Porteous, G Scotland, BH Smith, A Viljanen, M Heliövaara, JR Attia, I Sayers, R Hampel, C Gieger, IJ Deary, HM Boezen, A Newman, MR Jarvelin, JF Wilson, L Lind, BH Stricker, A Teumer, TD Spector, E Melén, MJ Peters, LA Lange, RG Barr, KR Bracke, FM Verhamme, J Sung, PS Hiemstra, PA Cassano, A Sood, C Hayward, J Dupuis, IP Hall, GG Brusselle, MD Tobin, SJ London
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Cardiac repolarization. The EFO term TPE interval measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Marjamaa, L Oikarinen, K Porthan, S Ripatti, G Peloso, PA Noseworthy, M Viitasalo, MS Nieminen, L Toivonen, K Kontula, L Peltonen, AS Havulinna, A Jula, CJ O'Donnell, C Newton-Cheh, M Perola, V Salomaa
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Adolescent idiopathic scoliosis (severe). The EFO term adolescent idiopathic scoliosis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Miyake, I Kou, Y Takahashi, TA Johnson, Y Ogura, J Dai, X Qiu, A Takahashi, H Jiang, H Yan, K Kono, N Kawakami, K Uno, M Ito, S Minami, H Yanagida, H Taneichi, N Hosono, T Tsuji, T Suzuki, H Sudo, T Kotani, I Yonezawa, M Kubo, T Tsunoda, K Watanabe, K Chiba, Y Toyama, Y Qiu, M Matsumoto, S Ikegawa
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Thyrotoxic hypokalemic periodic paralysis. The EFO term Thyrotoxic periodic paralysis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
W Jongjaroenprasert, T Phusantisampan, S Mahasirimongkol, T Mushiroda, N Hirankarn, T Snabboon, S Chanprasertyotin, P Tantiwong, S Soonthornpun, P Rattanapichart, S Mamanasiri, T Himathongkam, B Ongphiphadhanakul, A Takahashi, N Kamatani, M Kubo, Y Nakamura
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Primary tooth development (number of teeth). The EFO term odontogenesis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
D Pillas, CJ Hoggart, DM Evans, PF O'Reilly, K Sipilä, R Lähdesmäki, IY Millwood, M Kaakinen, G Netuveli, D Blane, P Charoen, U Sovio, A Pouta, N Freimer, AL Hartikainen, J Laitinen, S Vaara, B Glaser, P Crawford, NJ Timpson, SM Ring, G Deng, W Zhang, MI McCarthy, P Deloukas, L Peltonen, P Elliott, LJ Coin, GD Smith, MR Jarvelin
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was QT interval. The EFO term QT interval was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Pfeufer, S Sanna, DE Arking, M Müller, V Gateva, C Fuchsberger, GB Ehret, M Orrú, C Pattaro, A Köttgen, S Perz, G Usala, M Barbalic, M Li, B Pütz, A Scuteri, RJ Prineas, MF Sinner, C Gieger, SS Najjar, WH Kao, TW Mühleisen, M Dei, C Happle, S Möhlenkamp, L Crisponi, R Erbel, KH Jöckel, S Naitza, G Steinbeck, F Marroni, AA Hicks, E Lakatta, B Müller-Myhsok, PP Pramstaller, HE Wichmann, D Schlessinger, E Boerwinkle, T Meitinger, M Uda, J Coresh, S Kääb, GR Abecasis, A Chakravarti
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Depressive episodes in bipolar disorder. The EFO term depressive episode measurement, bipolar disorder was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Genes associated with Homo sapiens that interact with the MeSH term 'Doxorubicin' (D004317). Incorporates data from 20 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN
Genes down-regulated in comparison of monocytes treated with anti-TREM1 <a href='http://www.ncbi.nlm.nih.gov/gene/54210'>[GeneID=54210]</a> versus monocytes treated with anti-TREM1 <a href='http://www.ncbi.nlm.nih.gov/gene/54210'>[GeneID=54210]</a> and 5000 ng/ml LPS (TLR4 agonist).
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP
Genes up-regulated in comparison of monocytes treated with 5000 ng/ml LPS (TLR4 agonist) versus monocytes treated with anti-TREM1 <a href='http://www.ncbi.nlm.nih.gov/gene/54210'>[GeneID=54210]</a>.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP
Genes up-regulated in comparison of monocytes treated with 1 ng/ml LPS (TLR4 agonist) versus monocytes treated with anti-TREM1 <a href='http://www.ncbi.nlm.nih.gov/gene/54210'>[GeneID=54210]</a> and 5000 ng/ml LPS (TLR4 agonist).
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Pulmonary function (interaction). The EFO term FEV/FEC ratio was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
DB Hancock, M Soler Artigas, SA Gharib, A Henry, A Manichaikul, A Ramasamy, DW Loth, M Imboden, B Koch, WL McArdle, AV Smith, J Smolonska, A Sood, W Tang, JB Wilk, G Zhai, JH Zhao, H Aschard, KM Burkart, I Curjuric, M Eijgelsheim, P Elliott, X Gu, TB Harris, C Janson, G Homuth, PG Hysi, JZ Liu, LR Loehr, K Lohman, RJ Loos, AK Manning, KD Marciante, M Obeidat, DS Postma, MC Aldrich, GG Brusselle, TH Chen, G Eiriksdottir, N Franceschini, J Heinrich, JI Rotter, C Wijmenga, OD Williams, AR Bentley, A Hofman, CC Laurie, T Lumley, AC Morrison, BR Joubert, F Rivadeneira, DJ Couper, SB Kritchevsky, Y Liu, M Wjst, LV Wain, JM Vonk, AG Uitterlinden, T Rochat, SS Rich, BM Psaty, GT O'Connor, KE North, DB Mirel, B Meibohm, LJ Launer, KT Khaw, AL Hartikainen, CJ Hammond, S Gläser, J Marchini, P Kraft, NJ Wareham, H Völzke, BH Stricker, TD Spector, NM Probst-Hensch, D Jarvis, MR Jarvelin, SR Heckbert, V Gudnason, HM Boezen, RG Barr, PA Cassano, DP Strachan, M Fornage, IP Hall, J Dupuis, MD Tobin, SJ London
This gene set describes genes that are up-regulated in post-mortem lung samples from COVID-19-positive patients relative to biopsied healthy lung tissue from uninfected individuals. COVID-19 is the disease caused by SARS-CoV-2 virus. We define up-regulated as those genes that show a (log 2 fold change) of >=2. These data are from the supplementary materials associated with the publication. Note: the following HGNC id is part of this data set but was not recognized HGNC:13378.
Authors:
Daniel Blanco-Melo, Benjamin E Nilsson-Payant, Wen-Chun Liu, Skyler Uhl, Daisy Hoagland, Rasmus Møller, Tristan X Jordan, Kohei Oishi, Maryline Panis, David Sachs, Taia T Wang, Robert E Schwartz, Jean K Lim, Randy A Albrecht, Benjamin R tenOever
This set describes genes whose transcription is up-regulated in the whole blood of COVID-19 patients versus healthy donors. Genes listed in table S2 were mapped to ENSEMBL identifiers. Values are the reported log2 fold-change.
Authors:
Anna C Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer, Marie Oestreich, Nikolaos Antonakos, Melanie Nuesch-Germano, Konstantina Gkizeli, Lorenzo Bonaguro, Nico Reusch, Kevin Baßler, Maria Saridaki, Rainer Knoll, Tal Pecht, Theodore S Kapellos, Sarandia Doulou, Charlotte Kröger, Miriam Herbert, Lisa Holsten, Arik Horne, Ioanna D Gemünd, Nikoletta Rovina, Shobhit Agrawal, Kilian Dahm, Martina van Uelft, Anna Drews, Lena Lenkeit, Niklas Bruse, Jelle Gerretsen, Jannik Gierlich, Matthias Becker, Kristian Händler, Michael Kraut, Heidi Theis, Simachew Mengiste, Elena De Domenico, Jonas Schulte-Schrepping, Lea Seep, Jan Raabe, Christoph Hoffmeister, Michael ToVinh, Verena Keitel, Gereon Rieke, Valentina Talevi, Dirk Skowasch, N Ahmad Aziz, Peter Pickkers, Frank L van de Veerdonk, Mihai G Netea, Joachim L Schultze, Matthijs Kox, Monique M B Breteler, Jacob Nattermann, Antonia Koutsoukou, Evangelos J Giamarellos-Bourboulis, Thomas Ulas,
This set describes genes whose transcription is upregulated in the whole blood of severe COVID-19 patients versus healthy donors. Genes listed in table S2 were entered using ENSEMBL Gene identifiers. Values are the reported log2 fold-change.
Authors:
Anna C Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer, Marie Oestreich, Nikolaos Antonakos, Melanie Nuesch-Germano, Konstantina Gkizeli, Lorenzo Bonaguro, Nico Reusch, Kevin Baßler, Maria Saridaki, Rainer Knoll, Tal Pecht, Theodore S Kapellos, Sarandia Doulou, Charlotte Kröger, Miriam Herbert, Lisa Holsten, Arik Horne, Ioanna D Gemünd, Nikoletta Rovina, Shobhit Agrawal, Kilian Dahm, Martina van Uelft, Anna Drews, Lena Lenkeit, Niklas Bruse, Jelle Gerretsen, Jannik Gierlich, Matthias Becker, Kristian Händler, Michael Kraut, Heidi Theis, Simachew Mengiste, Elena De Domenico, Jonas Schulte-Schrepping, Lea Seep, Jan Raabe, Christoph Hoffmeister, Michael ToVinh, Verena Keitel, Gereon Rieke, Valentina Talevi, Dirk Skowasch, N Ahmad Aziz, Peter Pickkers, Frank L van de Veerdonk, Mihai G Netea, Joachim L Schultze, Matthijs Kox, Monique M B Breteler, Jacob Nattermann, Antonia Koutsoukou, Evangelos J Giamarellos-Bourboulis, Thomas Ulas,
This set describes genes whose transcription is upregulated in the whole blood of severe COVID-19 patients versus healthy donors. Genes listed in table S2 were entered using ENSEMBL Gene identifiers. Genes that could not be converted were omitted from the set. Values are the reported log2 fold-change.
Authors:
Anna C Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer, Marie Oestreich, Nikolaos Antonakos, Melanie Nuesch-Germano, Konstantina Gkizeli, Lorenzo Bonaguro, Nico Reusch, Kevin Baßler, Maria Saridaki, Rainer Knoll, Tal Pecht, Theodore S Kapellos, Sarandia Doulou, Charlotte Kröger, Miriam Herbert, Lisa Holsten, Arik Horne, Ioanna D Gemünd, Nikoletta Rovina, Shobhit Agrawal, Kilian Dahm, Martina van Uelft, Anna Drews, Lena Lenkeit, Niklas Bruse, Jelle Gerretsen, Jannik Gierlich, Matthias Becker, Kristian Händler, Michael Kraut, Heidi Theis, Simachew Mengiste, Elena De Domenico, Jonas Schulte-Schrepping, Lea Seep, Jan Raabe, Christoph Hoffmeister, Michael ToVinh, Verena Keitel, Gereon Rieke, Valentina Talevi, Dirk Skowasch, N Ahmad Aziz, Peter Pickkers, Frank L van de Veerdonk, Mihai G Netea, Joachim L Schultze, Matthijs Kox, Monique M B Breteler, Jacob Nattermann, Antonia Koutsoukou, Evangelos J Giamarellos-Bourboulis, Thomas Ulas,
Data from GEO GSE194368 and analyzed using GEO2R, only top gene shown. Authors identified transcriptional adaptations of GR signaling in the amygdala of humans with OUD. Thus, GRs, their coregulators and downstream systems may represent viable therapeutic targets to treat the “stress side” of OUD.
Authors:
Stephanie A Carmack, Janaina C M Vendruscolo, M Adrienne McGinn, Jorge Miranda-Barrientos, Vez Repunte-Canonigo, Gabriel D Bosse, Daniele Mercatelli, Federico M Giorgi, Yu Fu, Anthony J Hinrich, Francine M Jodelka, Karen Ling, Robert O Messing, Randall T Peterson, Frank Rigo, Scott Edwards, Pietro P Sanna, Marisela Morales, Michelle L Hastings, George F Koob, Leandro F Vendruscolo
Opioid use disorder_human_nucleus accumbens_coefficient
Description:
RNA sequencing on the dorsolateral prefrontal cortex (DLPFC) and nucleus accumbens (NAc) from unaffected comparison subjects (n = 20) and subjects diagnosed with opioid use disorder OUD (n = 20). Transcriptomic analyses identified differentially expressed transcripts and investigated the transcriptional coherence between brain regions using rank-rank hypergeometric orderlap.transcriptional differences by brain region in unaffected comparison subjects, finding unique transcriptional profiles in the DLPFC and NAc
Authors:
Marianne L Seney, Sam-Moon Kim, Jill R Glausier, Mariah A Hildebrand, Xiangning Xue, Wei Zong, Jiebiao Wang, Micah A Shelton, BaDoi N Phan, Chaitanya Srinivasan, Andreas R Pfenning, George C Tseng, David A Lewis, Zachary Freyberg, Ryan W Logan
GeneWeaver