List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Crohn's disease. The EFO term Crohn's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JC Barrett, S Hansoul, DL Nicolae, JH Cho, RH Duerr, JD Rioux, SR Brant, MS Silverberg, KD Taylor, MM Barmada, A Bitton, T Dassopoulos, LW Datta, T Green, AM Griffiths, EO Kistner, MT Murtha, MD Regueiro, JI Rotter, LP Schumm, AH Steinhart, SR Targan, RJ Xavier, C Libioulle, C Sandor, M Lathrop, J Belaiche, O Dewit, I Gut, S Heath, D Laukens, M Mni, P Rutgeerts, A Van Gossum, D Zelenika, D Franchimont, JP Hugot, M de Vos, S Vermeire, E Louis, LR Cardon, CA Anderson, H Drummond, E Nimmo, T Ahmad, NJ Prescott, CM Onnie, SA Fisher, J Marchini, J Ghori, S Bumpstead, R Gwilliam, M Tremelling, P Deloukas, J Mansfield, D Jewell, J Satsangi, CG Mathew, M Parkes, M Georges, MJ Daly
Striatum Gene Expression Correlates for NEPCOUNT45 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEPCOUNT45 measures Novel environment locomotion (activity beam breaks) 30-45 min in the periphery under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for NEPCOUNT45 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEPCOUNT45 measures Novel environment locomotion (activity beam breaks) 30-45 min in the periphery under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Striatum Gene Expression Correlates for NEPCOUNT45 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEPCOUNT45 measures Novel environment locomotion (activity beam breaks) 30-45 min in the periphery under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Striatum Gene Expression Correlates for NEPDIST45 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEPDIST45 measures Novel environment locomotion (cm) 30-45 min in the periphery under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for NEPDIST45 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEPDIST45 measures Novel environment locomotion (cm) 30-45 min in the periphery under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Striatum Gene Expression Correlates for NEPDIST45 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEPDIST45 measures Novel environment locomotion (cm) 30-45 min in the periphery under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
cocaine related behavior 2 (Cocrb2) spans 144.050573 - 194.050573 Mbp (NCBI Build 37) on Chr 1. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
QTL for ethanol conditioned taste aversion on Chr1 at NA (167.59 Mbp , Build 37)
Description:
ethanol conditioned taste aversion spans 142.59 - 192.59 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for cocaine related behavior on Chr1 at D1Ncvs12 (169.05 Mbp , Build 37)
Description:
cocaine related behavior spans 144.05 - 194.05 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for climbing on Chr1 at D1Ncvs12 (169.05 Mbp , Build 37)
Description:
METH responses for climbing spans 144.05 - 194.05 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for Acute ethanol sensitivity on Chr1 at NA (174.52 Mbp , Build 37)
Description:
Acute ethanol sensitivity spans 149.52 - 199.52 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Radcliffe RA, Bohl ML, Lowe MV, Cycowski CS, Wehner JM
QTL for differences in cocaine responsiveness on Chr1 at Mpmv-22 (181.89 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 156.89 - 206.89 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for differences in cocaine responsiveness on Chr1 at Pmv-21 (181.89 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 156.89 - 206.89 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for differences in cocaine responsiveness on Chr1 at D1MIt17 (181.89 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 156.89 - 206.89 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for activity response to ethanol on Chr1 at NA (184.43 Mbp , Build 37)
Description:
activity response to ethanol spans 159.43 - 209.43 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for morphine preference on Chr1 at NA (185.54 Mbp , Build 37)
Description:
morphine preference spans 160.54 - 210.54 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Berrettini WH, Ferraro TN, Alexander RC, Buchberg AM, Vogel WH
QTL for ethanol withdrawal on Chr1 at Xmv41 (190.14 Mbp , Build 37)
Description:
ethanol withdrawal spans 165.14 - 215.14 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol withdrawal on Chr1 at D1Mit206 (191.91 Mbp , Build 37)
Description:
alcohol withdrawal spans 166.91 - 216.91 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'pioglitazone' (C060836). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Hydrogen Peroxide' (D006861). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
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