List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was White blood cell types. The EFO term monocyte count was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Okada, T Hirota, Y Kamatani, A Takahashi, H Ohmiya, N Kumasaka, K Higasa, Y Yamaguchi-Kabata, N Hosono, MA Nalls, MH Chen, FJ van Rooij, AV Smith, T Tanaka, DJ Couper, NA Zakai, L Ferrucci, DL Longo, DG Hernandez, JC Witteman, TB Harris, CJ O'Donnell, SK Ganesh, K Matsuda, T Tsunoda, T Tanaka, M Kubo, Y Nakamura, M Tamari, K Yamamoto, N Kamatani
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was White blood cell count. The EFO term monocyte count was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
MA Nalls, DJ Couper, T Tanaka, FJ van Rooij, MH Chen, AV Smith, D Toniolo, NA Zakai, Q Yang, A Greinacher, AR Wood, M Garcia, P Gasparini, Y Liu, T Lumley, AR Folsom, AP Reiner, C Gieger, V Lagou, JF Felix, H Völzke, NA Gouskova, A Biffi, A Döring, U Völker, S Chong, KL Wiggins, A Rendon, A Dehghan, M Moore, K Taylor, JG Wilson, G Lettre, A Hofman, JC Bis, N Pirastu, CS Fox, C Meisinger, J Sambrook, S Arepalli, M Nauck, H Prokisch, J Stephens, NL Glazer, LA Cupples, Y Okada, A Takahashi, Y Kamatani, K Matsuda, T Tsunoda, T Tanaka, M Kubo, Y Nakamura, K Yamamoto, N Kamatani, M Stumvoll, A Tönjes, I Prokopenko, T Illig, KV Patel, SF Garner, B Kuhnel, M Mangino, BA Oostra, SL Thein, J Coresh, HE Wichmann, S Menzel, J Lin, G Pistis, AG Uitterlinden, TD Spector, A Teumer, G Eiriksdottir, V Gudnason, S Bandinelli, TM Frayling, A Chakravarti, CM van Duijn, D Melzer, WH Ouwehand, D Levy, E Boerwinkle, AB Singleton, DG Hernandez, DL Longo, N Soranzo, JC Witteman, BM Psaty, L Ferrucci, TB Harris, CJ O'Donnell, SK Ganesh
Whole brain expression correlates of ethanol withdrawal in BXD RI mice based on phenotype data in the 1997 Buck et al manuscript. Expression correlates were generated using GeneNetwork.org
Whole Brain Gene Expression Correlates for HAND_BASELINE measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The HAND_BASELINE measures Handling induced convulsion baseline under the domain Ethanol HIC. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Neocortex Gene Expression Correlates for MDMA_ACT_MDA_1 measured in BXD RI Females obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The MDMA_ACT_MDA_1 measures Locomotor response of 10 mg/kg MDMA injected on Day 2 under the domain MDMA. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for SPD_TIMEDOWEL30SEC measured in BXD RI Females & Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The SPD_TIMEDOWEL30SEC measures Dowel Test - Time 30 Sec under the domain Porsolt. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for SPD_TIMEDOWELBSEC measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The SPD_TIMEDOWELBSEC measures Dowel Test - Time B Sec under the domain Porsolt. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Annotated genes and anonymous ESTs differentially expressed in CD MIII biopsies in the presence or absence of dietary gluten, grouped according to known function. The indicated P-value is calculated from a Welch t-test. The level of up- or down-regulation in biopsies from MIII CD patients on gluten-free diet (gluten -) was expressed as the ratio of the average MIII gluten(-) and average MIII gluten(+), together with the calculated standard error (SE).
Authors:
Diosdado B, Wapenaar MC, Franke L, Duran KJ, Goerres MJ, Hadithi M, Crusius JB, Meijer JW, Duggan DJ, Mulder CJ, Holstege FC, Wijmenga C
QTL for alcohol preference on Chr2 at D2Mit61 (59.53 Mbp , Build 37)
Description:
alcohol preference spans 34.53 - 84.53 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for chewing on Chr2 at Hoxd (60.63 Mbp , Build 37)
Description:
METH responses for chewing spans 35.63 - 85.63 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol preference locus on Chr2 at NA (63.74 Mbp , Build 37)
Description:
alcohol preference locus spans 38.74 - 88.74 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol withdrawal on Chr2 at D2Mit9 (63.74 Mbp , Build 37)
Description:
alcohol withdrawal spans 38.74 - 88.74 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for activity response to ethanol on Chr2 at NA (80.10 Mbp , Build 37)
Description:
activity response to ethanol spans 55.10 - 105.10 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for ethanol response acute on Chr2 at NA (80.10 Mbp , Build 37)
Description:
ethanol response acute spans 55.10 - 105.10 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Demarest K, McCaughran J Jr, Mahjubi E, Cipp L, Hitzemann R
QTL for ethanol consumption on Chr2 at D2Mit14 (88.50 Mbp , Build 37)
Description:
ethanol consumption spans 63.50 - 113.50 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for ethanol induced locomotor activity on Chr2 at D2Mit94 (94.37 Mbp , Build 37)
Description:
ethanol induced locomotor activity spans 69.37 - 119.37 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Hitzemann R, Cipp L, Demarest K, Mahjubi E, McCaughran J Jr
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