List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Hypospadias. The EFO term hypospadias was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
F Geller, B Feenstra, L Carstensen, TH Pers, IA van Rooij, IB Körberg, S Choudhry, JM Karjalainen, TH Schnack, MV Hollegaard, WF Feitz, N Roeleveld, DM Hougaard, JN Hirschhorn, L Franke, LS Baskin, A Nordenskjöld, LF van der Zanden, M Melbye
QTL for METH responses for body temperature on Chr8 at D8Ncvs43 (95.66 Mbp , Build 37)
Description:
METH responses for body temperature spans 70.66 - 120.66 Mbp (NCBI Build 37) on Chr8. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'decitabine' (C014347). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Atrazine' (D001280). Incorporates data from 48 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '2-amino-4-phenylbutyric acid' (C014328). Incorporates data from 1822 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Cisplatin' (D002945). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Ethanol induced LORR Chr# 8 rs3666140 (44049661) with right flanking marker rs3661760(24557766) and left marker rs13479995 (116236688). This was mapped in 300 + (b6x129)F2 mice.
Ethanol Induced Ataxia Chr#8 rs3699406 (72486070) with right flanking marker rs6386110 (45897379) and left marker rs13479995(116236688). This was mapped in 300 + (b6x129)F2 mice.
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