This gene set comprises 399 genes that are differentially expressed within each of five brain regions (amygdale, hippocampus, nucleus accumbens, prefrontal cortex and ventral tegmental area) when chronic nicotine treatment is administered to C3H/HeJ mice only. Background: Studies involving use of chronic nicotine treatment identify unique nicotine addiction genes and the biological processes they control in B6 and C3 mice. Results are obtained using gene expression profiling and gene ontology.
Authors:
Wang J, Gutala R, Hwang YY, Kim JM, Konu O, Ma JZ, Li MD
This gene set comprises 85 genes that are upregulated within each of three overrepresented brain regions (nucleus accumbens (NA), prefrontal cortex (PFC) and ventral tegmental area (VTA)) when chronic nicotine treatment is administered to C3H/HeJ mice only. Background: Studies involving use of chronic nicotine treatment identify unique nicotine addiction genes and their resultant biological processes in C3H/HeJ and C57BL/6J mice. The entire study is done in five brain regions, amygdale (Amyg), hippocampus (HP), nucleus accumbens (NA), prefrontal cortex (PFC) and ventral tegmental area (VTA). Results are obtained using gene expression profiling via cDNA microarrays and gene ontology.
Authors:
Wang J, Gutala R, Hwang YY, Kim JM, Konu O, Ma JZ, Li MD
Hippocampus Gene Expression Correlates for VONFREYTHRESHOLDMEAN measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The VONFREYTHRESHOLDMEAN measures Mechanical Sensitivity-Von Frey Threshold under the domain Pain. The correlates were thresholded at a p-value of less than 0.001.
Hippocampus Gene Expression Correlates for VONFREYTHRESHOLDMEAN measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The VONFREYTHRESHOLDMEAN measures Mechanical Sensitivity-Von Frey Threshold under the domain Pain. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for PTOSIS measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The PTOSIS measures Morphine - Severity of ptosis under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for PTOSIS measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The PTOSIS measures Morphine - Severity of ptosis under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for PTOSIS measured in BXD RI Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The PTOSIS measures Morphine - Severity of ptosis under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for SPD_TIMEDOWEL30SEC measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The SPD_TIMEDOWEL30SEC measures Dowel Test - Time 30 Sec under the domain Porsolt. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for alcohol preference locus on Chr7 at D7Mit105 (126.73 Mbp , Build 37)
Description:
alcohol preference locus spans 101.73 - 151.73 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
alcohol preference locus 14, female specific at D7Mit105 with a LOD score of 1.84 (p < 0.004) spans and preference correlation of 0.591 101.73 - 151.73 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for home cage activity on Chr7 at D7Mit12 (129.57 Mbp , Build 37)
Description:
METH responses for home cage activity spans 104.57 - 154.57 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr7 at Xmv76 (137.02 Mbp , Build 37)
Description:
METH responses for body temperature spans 112.02 - 162.02 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL associated with "alcohol preference locus 12, male specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (135707912)
QTL associated with "alcohol preference locus 14, female specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (135707912)
QTL associated with behavioral response to methamphetamines 6. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (143722527)
QTL associated with cystic fibrosis body weight 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (126237672)
QTL associated with cystic fibrosis lung disease 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (126237672)
QTL associated with collagen induced arthritis 42. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (139448713)
QTL associated with determination of interleukin 4 commitment 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (136360966)
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