Pathway Commons (PC) Geneset. This geneset contains genes that participate in the "IL6-mediated signaling events" pathway. This set was automatically constructed using the PC API.
The original source of this geneset is pid.
gene2pc v. 0.1.0
Last updated 2015.08.31
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was C-reactive protein. The EFO term C-reactive protein measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Okada, A Takahashi, H Ohmiya, N Kumasaka, Y Kamatani, N Hosono, T Tsunoda, K Matsuda, T Tanaka, M Kubo, Y Nakamura, K Yamamoto, N Kamatani
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Cerebrospinal fluid clusterin levels in APOEe4- carriers. The EFO term Alzheimers disease, cerebrospinal fluid clusterin measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Deming, J Xia, Y Cai, J Lord, P Holmans, S Bertelsen, D Holtzman, JC Morris, K Bales, EH Pickering, J Kauwe, A Goate, C Cruchaga
GSE8515_IL1_VS_IL6_4H_STIM_)MAC_UP
Genes up-regulated in comparison of untreated macrophages versus those treated with IL1 and IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a>.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_UP
Genes up-regulated in comparison of untreated CD4 <a href='http://www.ncbi.nlm.nih.gov/gene/920'>[GeneID=920]</a> T cells versus those treated with IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a>.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
HALLMARK_IL6_JAK_STAT3_SIGNALING
Genes up-regulated by IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a> via STAT3 <a href='http://www.ncbi.nlm.nih.gov/gene/6774'>[GeneID=6774]</a>, e.g., during acute phase response.
h - Hallmark genesets containing coherently expressed signatures derived by aggregating many MSigDB gene sets to represent well-defined biological states or processes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_UP
Genes up-regulated in comparison of untreated CD4 <a href='http://www.ncbi.nlm.nih.gov/gene/920'>[GeneID=920]</a> T cells versus those treated with TGFB3 <a href='http://www.ncbi.nlm.nih.gov/gene/7043'>[GeneID=7043]</a> IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a>.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Longevity. The EFO term longevity was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Zeng, C Nie, J Min, X Liu, M Li, H Chen, H Xu, M Wang, T Ni, Y Li, H Yan, JP Zhang, C Song, LQ Chi, HM Wang, J Dong, GY Zheng, L Lin, F Qian, Y Qi, X Liu, H Cao, Y Wang, L Zhang, Z Li, Y Zhou, Y Wang, J Lu, J Li, M Qi, L Bolund, A Yashin, KC Land, S Gregory, Z Yang, W Gottschalk, W Tao, J Wang, J Wang, X Xu, H Bae, M Nygaard, L Christiansen, K Christensen, C Franceschi, MW Lutz, J Gu, Q Tan, T Perls, P Sebastiani, J Deelen, E Slagboom, E Hauser, H Xu, XL Tian, H Yang, JW Vaupel
GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP
Genes up-regulated in comparison of CD4 <a href='http://www.ncbi.nlm.nih.gov/gene/920'>[GeneID=920]</a> T cells treated with TGFB1 <a href='http://www.ncbi.nlm.nih.gov/gene/7040'>[GeneID=7040]</a> and IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a> versus those treated with TGFB1 <a href='http://www.ncbi.nlm.nih.gov/gene/7040'>[GeneID=7040]</a>, IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a> and IL23A <a href='http://www.ncbi.nlm.nih.gov/gene/51561'>[GeneID=51561]</a>.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_DN
Genes down-regulated in comparison of CD4 <a href='http://www.ncbi.nlm.nih.gov/gene/920'>[GeneID=920]</a> T cells treated with TGFB1 <a href='http://www.ncbi.nlm.nih.gov/gene/7040'>[GeneID=7040]</a> and IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a> versus those treated with TGFB1 <a href='http://www.ncbi.nlm.nih.gov/gene/7040'>[GeneID=7040]</a>, IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a> and IL23A <a href='http://www.ncbi.nlm.nih.gov/gene/51561'>[GeneID=51561]</a>.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_UP
Genes up-regulated in comparison of CD4 <a href='http://www.ncbi.nlm.nih.gov/gene/920'>[GeneID=920]</a> T cells treated with TGFB3 <a href='http://www.ncbi.nlm.nih.gov/gene/7043'>[GeneID=7043]</a> and IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a> versus those treated with TGF3B <a href='http://www.ncbi.nlm.nih.gov/gene/7043'>[GeneID=7043]</a>, IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a> and IL23A <a href='http://www.ncbi.nlm.nih.gov/gene/51561'>[GeneID=51561]</a>.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_DN
Genes down-regulated in comparison of CD4 <a href='http://www.ncbi.nlm.nih.gov/gene/920'>[GeneID=920]</a> T cells treated with TGFB3 <a href='http://www.ncbi.nlm.nih.gov/gene/7043'>[GeneID=7043]</a> and IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a> versus those treated with TGF3B <a href='http://www.ncbi.nlm.nih.gov/gene/7043'>[GeneID=7043]</a>, IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a> and IL23A <a href='http://www.ncbi.nlm.nih.gov/gene/51561'>[GeneID=51561]</a>.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_UP
Genes up-regulated in comparison of untreated CD4 <a href='http://www.ncbi.nlm.nih.gov/gene/920'>[GeneID=920]</a> T cells treated with IL1B <a href='http://www.ncbi.nlm.nih.gov/gene/3553'>[GeneID=3553]</a> and IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a> versus those treated with IL1B <a href='http://www.ncbi.nlm.nih.gov/gene/3553'>[GeneID=3553]</a>, IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a> and IL23A <a href='http://www.ncbi.nlm.nih.gov/gene/51561'>[GeneID=51561]</a>.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_DN
Genes down-regulated in comparison of untreated CD4 <a href='http://www.ncbi.nlm.nih.gov/gene/920'>[GeneID=920]</a> T cells treated with IL1B <a href='http://www.ncbi.nlm.nih.gov/gene/3553'>[GeneID=3553]</a> and IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a> versus those treated with IL1B <a href='http://www.ncbi.nlm.nih.gov/gene/3553'>[GeneID=3553]</a>, IL6 <a href='http://www.ncbi.nlm.nih.gov/gene/3569'>[GeneID=3569]</a> and IL23A <a href='http://www.ncbi.nlm.nih.gov/gene/51561'>[GeneID=51561]</a>.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Cerebrospinal fluid clusterin levels in APOEe4+ carriers. The EFO term APOE carrier status, cerebrospinal fluid clusterin measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Deming, J Xia, Y Cai, J Lord, P Holmans, S Bertelsen, D Holtzman, JC Morris, K Bales, EH Pickering, J Kauwe, A Goate, C Cruchaga
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Cerebrospinal fluid clusterin levels. The EFO term cerebrospinal fluid clusterin measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Deming, J Xia, Y Cai, J Lord, P Holmans, S Bertelsen, D Holtzman, JC Morris, K Bales, EH Pickering, J Kauwe, A Goate, C Cruchaga
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Plasma clusterin levels. The EFO term plasma clusterin measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Deming, J Xia, Y Cai, J Lord, P Holmans, S Bertelsen, D Holtzman, JC Morris, K Bales, EH Pickering, J Kauwe, A Goate, C Cruchaga
12 genes analyzed by PCR from 10 regions of the brains of male Wistar rats following morphine or saline administration. Data taken from Table 3. Values presented are "1" for presence.
Authors:
Timothy M Barrow, Hyang-Min Byun, Xinyan Li, Chris Smart, Yong-Xiang Wang, Yacong Zhang, Andrea A Baccarelli, Liqiong Guo
Belfer I, Wu T, Kingman A, Krishnaraju RK, Goldman D, Max MB
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