List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Serum protein levels (sST2). The EFO term serum ST2 measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JE Ho, WY Chen, MH Chen, MG Larson, EL McCabe, S Cheng, A Ghorbani, E Coglianese, V Emilsson, AD Johnson, S Walter, N Franceschini, CJ O'Donnell, A Dehghan, C Lu, D Levy, C Newton-Cheh, H Lin, JF Felix, ER Schreiter, RS Vasan, JL Januzzi, RT Lee, TJ Wang
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Asthma. The EFO term asthma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
MA Ferreira, AF McRae, SE Medland, DR Nyholt, SD Gordon, MJ Wright, AK Henders, PA Madden, PM Visscher, NR Wray, AC Heath, GW Montgomery, DL Duffy, NG Martin
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Allergic sensitization. The EFO term allergic sensitization measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
K Bønnelykke, MC Matheson, TH Pers, R Granell, DP Strachan, AC Alves, A Linneberg, JA Curtin, NM Warrington, M Standl, M Kerkhof, I Jonsdottir, BK Bukvic, M Kaakinen, P Sleimann, G Thorleifsson, U Thorsteinsdottir, K Schramm, S Baltic, E Kreiner-Møller, A Simpson, B St Pourcain, L Coin, J Hui, EH Walters, CM Tiesler, DL Duffy, G Jones, SM Ring, WL McArdle, L Price, CF Robertson, J Pekkanen, CS Tang, E Thiering, GW Montgomery, AL Hartikainen, SC Dharmage, LL Husemoen, C Herder, JP Kemp, P Elliot, A James, M Waldenberger, MJ Abramson, BP Fairfax, JC Knight, R Gupta, PJ Thompson, P Holt, P Sly, JN Hirschhorn, M Blekic, S Weidinger, H Hakonarsson, K Stefansson, J Heinrich, DS Postma, A Custovic, CE Pennell, MR Jarvelin, GH Koppelman, N Timpson, MA Ferreira, H Bisgaard, AJ Henderson
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Asthma. The EFO term asthma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
DG Torgerson, EJ Ampleford, GY Chiu, WJ Gauderman, CR Gignoux, PE Graves, BE Himes, AM Levin, RA Mathias, DB Hancock, JW Baurley, C Eng, DA Stern, JC Celedón, N Rafaels, D Capurso, DV Conti, LA Roth, M Soto-Quiros, A Togias, X Li, RA Myers, I Romieu, DJ Van Den Berg, D Hu, NN Hansel, RD Hernandez, E Israel, MT Salam, J Galanter, PC Avila, L Avila, JR Rodriquez-Santana, R Chapela, W Rodriguez-Cintron, GB Diette, NF Adkinson, RA Abel, KD Ross, M Shi, MU Faruque, GM Dunston, HR Watson, VJ Mantese, SC Ezurum, L Liang, I Ruczinski, JG Ford, S Huntsman, KF Chung, H Vora, X Li, WJ Calhoun, M Castro, JJ Sienra-Monge, B del Rio-Navarro, KA Deichmann, A Heinzmann, SE Wenzel, WW Busse, JE Gern, RF Lemanske, TH Beaty, ER Bleecker, BA Raby, DA Meyers, SJ London, FD Gilliland, EG Burchard, FD Martinez, ST Weiss, LK Williams, KC Barnes, C Ober, DL Nicolae
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Atopic dermatitis. The EFO term atopic eczema was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
T Hirota, A Takahashi, M Kubo, T Tsunoda, K Tomita, M Sakashita, T Yamada, S Fujieda, S Tanaka, S Doi, A Miyatake, T Enomoto, C Nishiyama, N Nakano, K Maeda, K Okumura, H Ogawa, S Ikeda, E Noguchi, T Sakamoto, N Hizawa, K Ebe, H Saeki, T Sasaki, T Ebihara, M Amagai, S Takeuchi, M Furue, Y Nakamura, M Tamari
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Eosinophil counts. The EFO term eosinophil count was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
DF Gudbjartsson, US Bjornsdottir, E Halapi, A Helgadottir, P Sulem, GM Jonsdottir, G Thorleifsson, H Helgadottir, V Steinthorsdottir, H Stefansson, C Williams, J Hui, J Beilby, NM Warrington, A James, LJ Palmer, GH Koppelman, A Heinzmann, M Krueger, HM Boezen, A Wheatley, J Altmuller, HD Shin, ST Uh, HS Cheong, B Jonsdottir, D Gislason, CS Park, LM Rasmussen, C Porsbjerg, JW Hansen, V Backer, T Werge, C Janson, UB Jönsson, MC Ng, J Chan, WY So, R Ma, SH Shah, CB Granger, AA Quyyumi, AI Levey, V Vaccarino, MP Reilly, DJ Rader, MJ Williams, AM van Rij, GT Jones, E Trabetti, G Malerba, PF Pignatti, A Boner, L Pescollderungg, D Girelli, O Olivieri, N Martinelli, BR Ludviksson, D Ludviksdottir, GI Eyjolfsson, D Arnar, G Thorgeirsson, K Deichmann, PJ Thompson, M Wjst, IP Hall, DS Postma, T Gislason, J Gulcher, A Kong, I Jonsdottir, U Thorsteinsdottir, K Stefansson
Cerebellum Gene Expression Correlates for C2HCOUNT60 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The C2HCOUNT60 measures Open Field locomotion (activity beam breaks) 45-60 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for C2HDIS60 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The C2HDIS60 measures Open Field Total34 horizontal distance (cm) 45-60 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for C2VCOUNT60 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The C2VCOUNT60 measures Open Field rears 45-60 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for OF_CORNER_TIME_PCT measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The OF_CORNER_TIME_PCT measures Open Field - Total time in corners under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for OF_CORNER_TIME_PCT measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The OF_CORNER_TIME_PCT measures Open Field - Total time in corners under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Striatum Gene Expression Correlates for SHDIST30 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The SHDIST30 measures Open Field - Total horizontal distance (cm) 15-30 min post saline (10 ml/kg) under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for ST_PCT_PPI_80 measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The ST_PCT_PPI_80 measures Prepulse inhibition at 80db under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for ST_PCT_PPI_85 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The ST_PCT_PPI_85 measures Prepulse inhibition at 85db under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for ST_PCT_STARTLE_80 measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The ST_PCT_STARTLE_80 measures Acoustic Startle Response Percentage of maximum startle response at 80 db under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for ST_PCT_STARTLE_85 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The ST_PCT_STARTLE_85 measures Acoustic Startle Response Percentage of maximum response at 85 db under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for VOCA_THRESHOLD measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The VOCA_THRESHOLD measures Vocalization Threshold - shock intensity (mA) under the domain Stress Vocalization. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for VOCA_THRESHOLD measured in BXD RI Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The VOCA_THRESHOLD measures Vocalization Threshold - shock intensity (mA) under the domain Stress Vocalization. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
The genes that were significantly changed in expression in each disease are summarized in Table 1. Of interest is the upregu- lation of CCL11 (also known as eotaxin) exclusively in UC. While chemokines play a role in all inflammatory diseases, celiac disease is relatively independent of chemokine expres- sion. A unique feature for UC and CD is the increased transcript levels for the proinflammatory cytokine IL-1
Authors:
van der Pouw Kraan TC, Zwiers A, Mulder CJ, Kraal G, Bouma G
The genes that were significantly changed in expression in each disease are summarized in Table 1. Of interest is the upregu- lation of CCL11 (also known as eotaxin) exclusively in UC. While chemokines play a role in all inflammatory diseases, celiac disease is relatively independent of chemokine expres- sion. A unique feature for UC and CD is the increased transcript levels for the proinflammatory cytokine IL-1
Authors:
van der Pouw Kraan TC, Zwiers A, Mulder CJ, Kraal G, Bouma G
The genes that were significantly changed in expression in each disease are summarized in Table 1. Of interest is the upregu- lation of CCL11 (also known as eotaxin) exclusively in UC. While chemokines play a role in all inflammatory diseases, celiac disease is relatively independent of chemokine expres- sion. A unique feature for UC and CD is the increased transcript levels for the proinflammatory cytokine IL-1
Authors:
van der Pouw Kraan TC, Zwiers A, Mulder CJ, Kraal G, Bouma G
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