Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "interleukin-12 complex", which is defined as "A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
"A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space." [GOC:add, PMID:11114383, PMID:15999093]
"A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space." [GOC:add, GOC:ebc, GOC:mah, PMID:12948519, PMID:1381512]
"A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space." [GOC:add, PMID:11114383, PMID:15999093]
"A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space." [GOC:add, GOC:ebc, GOC:mah, PMID:12948519, PMID:1381512]
Genes containing SNVs that were identified in the discovery sequencing (phase I) and passed filtering for the Inflammatory Bowel Disease Associated Rare Variant analysis.
Authors:
Prescott NJ, Lehne B, Stone K, Lee JC, Taylor K, Knight J, Papouli E, Mirza MM, Simpson MA, Spain SL, Lu G, Fraternali F, Bumpstead SJ, Gray E, Amar A, Bye H, Green P, Chung-Faye G, Hayee B, Pollok R, Satsangi J, Parkes M, Barrett JC, Mansfield JC, Sanderson J, Lewis CM, Weale ME, Schlitt T, Mathew CG
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Ankylosing spondylitis. The EFO term ankylosing spondylitis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
DM Evans, CC Spencer, JJ Pointon, Z Su, D Harvey, G Kochan, U Oppermann, U Opperman, A Dilthey, M Pirinen, MA Stone, L Appleton, L Moutsianas, L Moutsianis, S Leslie, T Wordsworth, TJ Kenna, T Karaderi, GP Thomas, MM Ward, MH Weisman, C Farrar, LA Bradbury, P Danoy, RD Inman, W Maksymowych, D Gladman, P Rahman, A Morgan, H Marzo-Ortega, P Bowness, K Gaffney, JS Gaston, M Smith, J Bruges-Armas, AR Couto, R Sorrentino, F Paladini, MA Ferreira, H Xu, Y Liu, L Jiang, C Lopez-Larrea, R DÃaz-Peña, A López-Vázquez, T Zayats, G Band, C Bellenguez, H Blackburn, JM Blackwell, E Bramon, SJ Bumpstead, JP Casas, A Corvin, N Craddock, P Deloukas, S Dronov, A Duncanson, S Edkins, C Freeman, M Gillman, E Gray, R Gwilliam, N Hammond, SE Hunt, J Jankowski, A Jayakumar, C Langford, J Liddle, HS Markus, CG Mathew, OT McCann, MI McCarthy, CN Palmer, L Peltonen, R Plomin, SC Potter, A Rautanen, R Ravindrarajah, M Ricketts, N Samani, SJ Sawcer, A Strange, RC Trembath, AC Viswanathan, M Waller, P Weston, P Whittaker, S Widaa, NW Wood, G McVean, JD Reveille, BP Wordsworth, MA Brown, P Donnelly
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Cutaneous psoriasis. The EFO term cutaneous psoriasis measurement, psoriasis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das, HM Kang, E Ellinghaus, V Chandran, K Callis-Duffin, R Ike, Y Li, X Wen, C Enerbäck, JE Gudjonsson, S Kõks, K Kingo, T Esko, U Mrowietz, A Reis, HE Wichmann, C Gieger, P Hoffmann, MM Nöthen, J Winkelmann, M Kunz, EG Moreta, PJ Mease, CT Ritchlin, AM Bowcock, GG Krueger, HW Lim, S Weidinger, M Weichenthal, JJ Voorhees, P Rahman, PK Gregersen, A Franke, DD Gladman, GR Abecasis, JT Elder
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Psoriasis vulgaris. The EFO term psoriasis vulgaris was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das, HM Kang, E Ellinghaus, V Chandran, K Callis-Duffin, R Ike, Y Li, X Wen, C Enerbäck, JE Gudjonsson, S Kõks, K Kingo, T Esko, U Mrowietz, A Reis, HE Wichmann, C Gieger, P Hoffmann, MM Nöthen, J Winkelmann, M Kunz, EG Moreta, PJ Mease, CT Ritchlin, AM Bowcock, GG Krueger, HW Lim, S Weidinger, M Weichenthal, JJ Voorhees, P Rahman, PK Gregersen, A Franke, DD Gladman, GR Abecasis, JT Elder
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Psoriatic arthritis. The EFO term psoriatic arthritis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das, HM Kang, E Ellinghaus, V Chandran, K Callis-Duffin, R Ike, Y Li, X Wen, C Enerbäck, JE Gudjonsson, S Kõks, K Kingo, T Esko, U Mrowietz, A Reis, HE Wichmann, C Gieger, P Hoffmann, MM Nöthen, J Winkelmann, M Kunz, EG Moreta, PJ Mease, CT Ritchlin, AM Bowcock, GG Krueger, HW Lim, S Weidinger, M Weichenthal, JJ Voorhees, P Rahman, PK Gregersen, A Franke, DD Gladman, GR Abecasis, JT Elder
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Psoriasis. The EFO term psoriasis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
X Yin, HQ Low, L Wang, Y Li, E Ellinghaus, J Han, X Estivill, L Sun, X Zuo, C Shen, C Zhu, A Zhang, F Sanchez, L Padyukov, JJ Catanese, GG Krueger, KC Duffin, S Mucha, M Weichenthal, S Weidinger, W Lieb, JN Foo, Y Li, K Sim, H Liany, I Irwan, Y Teo, CT Theng, R Gupta, A Bowcock, PL De Jager, AA Qureshi, PI de Bakker, M Seielstad, W Liao, M Ståhle, A Franke, X Zhang, J Liu
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Psoriatic arthritis. The EFO term psoriatic arthritis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
U Hüffmeier, S Uebe, AB Ekici, J Bowes, E Giardina, E Korendowych, K Juneblad, M Apel, R McManus, P Ho, IN Bruce, AW Ryan, F Behrens, J Lascorz, B Böhm, H Traupe, J Lohmann, C Gieger, HE Wichmann, C Herold, M Steffens, L Klareskog, TF Wienker, O Fitzgerald, GM Alenius, NJ McHugh, G Novelli, H Burkhardt, A Barton, A Reis
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Ulcerative colitis. The EFO term ulcerative colitis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Psoriasis. The EFO term psoriasis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
XJ Zhang, W Huang, S Yang, LD Sun, FY Zhang, QX Zhu, FR Zhang, C Zhang, WH Du, XM Pu, H Li, FL Xiao, ZX Wang, Y Cui, F Hao, J Zheng, XQ Yang, H Cheng, CD He, XM Liu, LM Xu, HF Zheng, SM Zhang, JZ Zhang, HY Wang, YL Cheng, BH Ji, QY Fang, YZ Li, FS Zhou, JW Han, C Quan, B Chen, JL Liu, D Lin, L Fan, AP Zhang, SX Liu, CJ Yang, PG Wang, WM Zhou, GS Lin, WD Wu, X Fan, M Gao, BQ Yang, WS Lu, Z Zhang, KJ Zhu, SK Shen, M Li, XY Zhang, TT Cao, W Ren, X Zhang, J He, XF Tang, S Lu, JQ Yang, L Zhang, DN Wang, F Yuan, XY Yin, HJ Huang, HF Wang, XY Lin, JJ Liu
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Psoriasis. The EFO term psoriasis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
RP Nair, KC Duffin, C Helms, J Ding, PE Stuart, D Goldgar, JE Gudjonsson, Y Li, T Tejasvi, BJ Feng, A Ruether, S Schreiber, M Weichenthal, D Gladman, P Rahman, SJ Schrodi, S Prahalad, SL Guthery, J Fischer, W Liao, PY Kwok, A Menter, GM Lathrop, CA Wise, AB Begovich, JJ Voorhees, JT Elder, GG Krueger, AM Bowcock, GR Abecasis
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Psoriasis. The EFO term psoriasis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Liu, C Helms, W Liao, LC Zaba, S Duan, J Gardner, C Wise, A Miner, MJ Malloy, CR Pullinger, JP Kane, S Saccone, J Worthington, I Bruce, PY Kwok, A Menter, J Krueger, A Barton, NL Saccone, AM Bowcock
Cerebellum Gene Expression Correlates for C1VCOUNT15 measured in BXD RI Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The C1VCOUNT15 measures Open Field rears 0-15 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for SALINE_ACOUNT_2 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The SALINE_ACOUNT_2 measures Open Field TOTAL locomotion (activity beam breaks) under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for SALINE_ADIST_2 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The SALINE_ADIST_2 measures Open Field TOTAL locomotion ( cm in 1 hr) under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
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