List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Acute lymphoblastic leukemia (childhood). The EFO term acute lymphoblastic leukemia was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
TJ Evans, E Milne, D Anderson, NH de Klerk, SE Jamieson, BA Talseth-Palmer, NA Bowden, EG Holliday, J Rudant, L Orsi, E Richardson, L Lavis, D Catchpoole, JR Attia, BK Armstrong, J Clavel, RJ Scott
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was IgG glycosylation. The EFO term serum IgG glycosylation measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
G Lauc, JE Huffman, M Pučić, L Zgaga, B Adamczyk, A Mužinić, M Novokmet, O Polašek, O Gornik, J Krištić, T Keser, V Vitart, B Scheijen, HW Uh, M Molokhia, AL Patrick, P McKeigue, I Kolčić, IK Lukić, O Swann, FN van Leeuwen, LR Ruhaak, JJ Houwing-Duistermaat, PE Slagboom, M Beekman, AJ de Craen, AM Deelder, Q Zeng, W Wang, ND Hastie, U Gyllensten, JF Wilson, M Wuhrer, AF Wright, PM Rudd, C Hayward, Y Aulchenko, H Campbell, I Rudan
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Acute lymphoblastic leukemia (childhood). The EFO term acute lymphoblastic leukemia was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
E Papaemmanuil, FJ Hosking, J Vijayakrishnan, A Price, B Olver, E Sheridan, SE Kinsey, T Lightfoot, E Roman, JA Irving, JM Allan, IP Tomlinson, M Taylor, M Greaves, RS Houlston
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Systemic lupus erythematosus. The EFO term systemic lupus erythematosus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JW Han, HF Zheng, Y Cui, LD Sun, DQ Ye, Z Hu, JH Xu, ZM Cai, W Huang, GP Zhao, HF Xie, H Fang, QJ Lu, JH Xu, XP Li, YF Pan, DQ Deng, FQ Zeng, ZZ Ye, XY Zhang, QW Wang, F Hao, L Ma, XB Zuo, FS Zhou, WH Du, YL Cheng, JQ Yang, SK Shen, J Li, YJ Sheng, XX Zuo, WF Zhu, F Gao, PL Zhang, Q Guo, B Li, M Gao, FL Xiao, C Quan, C Zhang, Z Zhang, KJ Zhu, Y Li, DY Hu, WS Lu, JL Huang, SX Liu, H Li, YQ Ren, ZX Wang, CJ Yang, PG Wang, WM Zhou, YM Lv, AP Zhang, SQ Zhang, D Lin, Y Li, HQ Low, M Shen, ZF Zhai, Y Wang, FY Zhang, S Yang, JJ Liu, XJ Zhang
GWAS: Stevens-Johnson syndrome, toxic epidermal necrolysis, response to cold medicine
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Cold medicine related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS-TEN) with severe mucosal involvement. The EFO term Stevens-Johnson syndrome, toxic epidermal necrolysis, response to cold medicine was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Ueta, H Sawai, C Sotozono, Y Hitomi, N Kaniwa, MK Kim, KY Seo, KC Yoon, CK Joo, C Kannabiran, TH Wakamatsu, V Sangwan, V Rathi, S Basu, T Ozeki, T Mushiroda, E Sugiyama, K Maekawa, R Nakamura, M Aihara, K Matsunaga, A Sekine, JÁ Gomes, J Hamuro, Y Saito, M Kubo, S Kinoshita, K Tokunaga
UCSD Cerebellum Development, Gene by age model - WT parabolic, Sg-,Sg- parabolic Cerebellum Developmental Gene Expression Staggerer Mutant, WT parabolic, Sg-,Sg- parabolic across early development
Expression of 103 genes were detected in purified samples, but significantly downregulated in whole samples (P<0.05), of which 33 of these were significant at P<0.01 (Table 3) which are displayed in the Heatmaps
Authors:
Smith MJ, Culhane AC, Donovan M, Coffey JC, Barry BD, Kelly MA, Higgins DG, Wang JH, Kirwan WO, Cotter TG, Redmond HP
Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test; from Flatscher-Bader et al., 2005
Authors:
Flatscher-Bader T, van der Brug M, Hwang JW, Gochee PA, Matsumoto I, Niwa S, Wilce PA
cocaine related behavior 11 (Cocrb11) spans 0 - 27.768945 Mbp (NCBI Build 37) on Chr 11. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
QTL for differences in cocaine responsiveness on Chr11 at D11M!t2 (8.35 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 0.00 - 33.35 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for cocaine related behavior on Chr11 at Glns-ps1 (18.69 Mbp , Build 37)
Description:
cocaine related behavior spans 0.00 - 43.69 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for chronic alcohol withdrawal severity on Chr11 at D11Mit340 (18.69 Mbp , Build 37)
Description:
chronic alcohol withdrawal severity spans 0.00 - 43.69 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Bergeson SE, Kyle Warren R, Crabbe JC, Metten P, Gene Erwin V, Belknap JK
QTL for nicotine sensitivity on Chr11 at D11Mit82 (21.63 Mbp , Build 37)
Description:
nicotine sensitivity spans 0.00 - 46.63 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol withdrawal on Chr11 at D11Mit174 (30.34 Mbp , Build 37)
Description:
alcohol withdrawal spans 5.34 - 55.34 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for high-dose ethanol actions on Chr11 at GABRA1 (32.49 Mbp , Build 37)
Description:
high-dose ethanol actions spans 7.49 - 57.49 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Erwin VG, Markel PD, Johnson TE, Gehle VM, Jones BC
Genes associated with Homo sapiens that interact with the MeSH term '4,5,6,7-tetrabromobenzotriazole' (C405354). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'Ionomycin' (D015759). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
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