QTL for nicotine sensitivity on Chr16 at D16Mit131 (8.72 Mbp , Build 37)
Description:
nicotine sensitivity spans 0.00 - 33.72 Mbp (NCBI Build 37) on Chr16. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for home cage activity on Chr16 at Comt (22.04 Mbp , Build 37)
Description:
METH responses for home cage activity spans 0.00 - 47.04 Mbp (NCBI Build 37) on Chr16. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'Aspirin' (D001241). Incorporates data from 43 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Ethanol Induced Hypothermia Chr# 16 rs4182243(46052770) with right flanking marker rs4165065(17412172) and left marker rs4200124(70695141). This was mapped in 300 + (b6x129)F2 mice.
"A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism." [GOC:jl]
As a treatment of ulcerative colitis the entire large bowel is resected, and the unaffected small bowel is used to create a reservoir (pouch) connected to the anal canal [restorative proctocolectomy with an ileal pouch–anal anastomosis (IPAA)]. Pouch inflammation, “pouchitis,” is the most prevalent long-term complication in patients with UC, with a reported incidence of up to 60%. Approximatly 490 transcripts were differentially expressed in chronic pouchitis compared to normal controls. P value uploaded.
Authors:
Ben-Shachar S, Yanai H, Baram L, Elad H, Meirovithz E, Ofer A, Brazowski E, Tulchinsky H, Pasmanik-Chor M, Dotan I
As a treatment of ulcerative colitis the entire large bowel is resected, and the unaffected small bowel is used to create a reservoir (pouch) connected to the anal canal [restorative proctocolectomy with an ileal pouch–anal anastomosis (IPAA)]. Crohn’s-like disease of the pouch (CLDP) such as fistulas, strictures, or inflammation of ileal segments proximal to the pouchpatients with CLDP had 1152 significantly altered transcripts compared with NC. P-value uploaded.
Authors:
Ben-Shachar S, Yanai H, Baram L, Elad H, Meirovithz E, Ofer A, Brazowski E, Tulchinsky H, Pasmanik-Chor M, Dotan I
chr22q11
Genes in cytogenetic band chr22q11
c1 - Positional genesets for each human chromosome and cytogenetic band.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
NOTCH_DN.V1_DN
Genes down-regulated in MOLT4 cells (T-ALL) by DAPT <a href='http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=16219261'>[PubChem=16219261]</a>, an inhibitor of NOTCH signaling pathway.
c6 - Genesets containing oncogenic signatures defined directly from microarray gene expression data from cancer gene perturbations.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
Binding and Uptake of Ligands by Scavenger Receptors
Description:
Pathway Commons (PC) Geneset. This geneset contains genes that participate in the "Binding and Uptake of Ligands by Scavenger Receptors" pathway. This set was automatically constructed using the PC API.
The original source of this geneset is Reactome.
gene2pc v. 0.1.0
Last updated 2015.08.31
Pathway Commons (PC) Geneset. This geneset contains genes that participate in the "Homo sapiens" pathway. This set was automatically constructed using the PC API.
The original source of this geneset is miRTarBase.
gene2pc v. 0.1.0
Last updated 2015.08.31
The first complement component to act in the activation of CLASSICAL COMPLEMENT PATHWAY. It is a calcium-dependent trimolecular complex made up of three subcomponents: COMPLEMENT C1Q; COMPLEMENT C1R; and COMPLEMENT C1S at 1:2:2 ratios. When the intact C1 binds to at least two antibodies (involving C1q), C1r and C1s are sequentially activated, leading to subsequent steps in the cascade of COMPLEMENT ACTIVATION.
Generated by gene2mesh v. 1.1.1
The PROTEIN SUBUNITS of the multimeric IMMUNOGLOBULIN proteins, such as IGA; IGD; IGE; IGG; and IGM. Included are the heavy and light chains which contain the specific ANTIGEN binding domains, as well as the accessory proteins that are part of the the secreted forms of IGM and IGA; (SECRETORY IGA).
Generated by gene2mesh v. 1.1.1
Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.
Generated by gene2mesh v. 1.1.1
Enzymes that catalyze the hydrolysis of the internal bonds and thereby the formation of polynucleotides or oligonucleotides from ribo- or deoxyribonucleotide chains. EC 3.1.-.
Generated by gene2mesh v. 1.1.1
Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques.
Generated by gene2mesh v. 1.1.1
Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.
Generated by gene2mesh v. 1.1.1
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
Generated by gene2mesh v. 1.1.1
The chemical processes, enzymatic activities, and pathways of living things and related temporal, dimensional, qualitative, and quantitative concepts.
Generated by gene2mesh v. 1.1.1
GeneWeaver