List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Ulcerative colitis. The EFO term ulcerative colitis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JC Barrett, JC Lee, CW Lees, NJ Prescott, CA Anderson, A Phillips, E Wesley, K Parnell, H Zhang, H Drummond, ER Nimmo, D Massey, K Blaszczyk, T Elliott, L Cotterill, H Dallal, AJ Lobo, C Mowat, JD Sanderson, DP Jewell, WG Newman, C Edwards, T Ahmad, JC Mansfield, J Satsangi, M Parkes, CG Mathew, P Donnelly, L Peltonen, JM Blackwell, E Bramon, MA Brown, JP Casas, A Corvin, N Craddock, P Deloukas, A Duncanson, J Jankowski, HS Markus, CG Mathew, MI McCarthy, CN Palmer, R Plomin, A Rautanen, SJ Sawcer, N Samani, RC Trembath, AC Viswanathan, N Wood, CC Spencer, JC Barrett, C Bellenguez, D Davison, C Freeman, A Strange, P Donnelly, C Langford, SE Hunt, S Edkins, R Gwilliam, H Blackburn, SJ Bumpstead, S Dronov, M Gillman, E Gray, N Hammond, A Jayakumar, OT McCann, J Liddle, ML Perez, SC Potter, R Ravindrarajah, M Ricketts, M Waller, P Weston, S Widaa, P Whittaker, P Deloukas, L Peltonen, CG Mathew, JM Blackwell, MA Brown, A Corvin, MI McCarthy, CC Spencer, AP Attwood, J Stephens, J Sambrook, WH Ouwehand, WL McArdle, SM Ring, DP Strachan
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JS Kooner, D Saleheen, X Sim, J Sehmi, W Zhang, P Frossard, LF Been, KS Chia, AS Dimas, N Hassanali, T Jafar, JB Jowett, X Li, V Radha, SD Rees, F Takeuchi, R Young, T Aung, A Basit, M Chidambaram, D Das, E Grundberg, AK Hedman, ZI Hydrie, M Islam, CC Khor, S Kowlessur, MM Kristensen, S Liju, WY Lim, DR Matthews, J Liu, AP Morris, AC Nica, JM Pinidiyapathirage, I Prokopenko, A Rasheed, M Samuel, N Shah, AS Shera, KS Small, C Suo, AR Wickremasinghe, TY Wong, M Yang, F Zhang, GR Abecasis, AH Barnett, M Caulfield, P Deloukas, TM Frayling, P Froguel, N Kato, P Katulanda, MA Kelly, J Liang, V Mohan, DK Sanghera, J Scott, M Seielstad, PZ Zimmet, P Elliott, YY Teo, MI McCarthy, J Danesh, ES Tai, JC Chambers
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
YS Cho, CH Chen, C Hu, J Long, RT Ong, X Sim, F Takeuchi, Y Wu, MJ Go, T Yamauchi, YC Chang, SH Kwak, RC Ma, K Yamamoto, LS Adair, T Aung, Q Cai, LC Chang, YT Chen, Y Gao, FB Hu, HL Kim, S Kim, YJ Kim, JJ Lee, NR Lee, Y Li, JJ Liu, W Lu, J Nakamura, E Nakashima, DP Ng, WT Tay, FJ Tsai, TY Wong, M Yokota, W Zheng, R Zhang, C Wang, WY So, K Ohnaka, H Ikegami, K Hara, YM Cho, NH Cho, TJ Chang, Y Bao, Ã…K Hedman, AP Morris, MI McCarthy, R Takayanagi, KS Park, W Jia, LM Chuang, JC Chan, S Maeda, T Kadowaki, JY Lee, JY Wu, YY Teo, ES Tai, XO Shu, KL Mohlke, N Kato, BG Han, M Seielstad
Top tier were previously reported at genome-wide significance (5×10−8), bottom tier were previously reported with weaker evidence. P values are one-tailed in the direction of the previously reported association.
Authors:
Barrett JC, Lee JC, Lees CW, Prescott NJ, Anderson CA, Phillips A, Wesley E, Parnell K, Zhang H, Drummond H, Nimmo ER, Massey D, Blaszczyk K, Elliott T, Cotterill L, Dallal H, Lobo AJ, Mowat C, Sanderson JD, Jewell DP, Newman WG, Edwards C, Ahmad T, Mansfield JC, Satsangi J, Parkes M, Mathew CG, Donnelly P, Peltonen L, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin A, Craddock N, Deloukas P, Duncanson A, Jankowski J, Markus HS, Mathew CG, McCarthy MI, Palmer CN, Plomin R, Rautanen A, Sawcer SJ, Samani N, Trembath RC, Viswanathan AC, Wood N, Spencer CC, Barrett JC, Bellenguez C, Davison D, Freeman C, Strange A, Donnelly P, Langford C, Hunt SE, Edkins S, Gwilliam R, Blackburn H, Bumpstead SJ, Dronov S, Gillman M, Gray E, Hammond N, Jayakumar A, McCann OT, Liddle J, Perez ML, Potter SC, Ravindrarajah R, Ricketts M, Waller M, Weston P, Widaa S, Whittaker P, Deloukas P, Peltonen L, Mathew CG, Blackwell JM, Brown MA, Corvin A, McCarthy MI, Spencer CC, Attwood AP, Stephens J, Sambrook J, Ouwehand WH, McArdle WL, Ring SM, Strachan DP
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was C-reactive protein. The EFO term C-reactive protein measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
AP Reiner, S Beleza, N Franceschini, PL Auer, JG Robinson, C Kooperberg, U Peters, H Tang
GWAS: high density lipoprotein cholesterol measurement
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was HDL cholesterol. The EFO term high density lipoprotein cholesterol measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
S Kathiresan, CJ Willer, GM Peloso, S Demissie, K Musunuru, EE Schadt, L Kaplan, D Bennett, Y Li, T Tanaka, BF Voight, LL Bonnycastle, AU Jackson, G Crawford, A Surti, C Guiducci, NP Burtt, S Parish, R Clarke, D Zelenika, KA Kubalanza, MA Morken, LJ Scott, HM Stringham, P Galan, AJ Swift, J Kuusisto, RN Bergman, J Sundvall, M Laakso, L Ferrucci, P Scheet, S Sanna, M Uda, Q Yang, KL Lunetta, J Dupuis, PI de Bakker, CJ O'Donnell, JC Chambers, JS Kooner, S Hercberg, P Meneton, EG Lakatta, A Scuteri, D Schlessinger, J Tuomilehto, FS Collins, L Groop, D Altshuler, R Collins, GM Lathrop, O Melander, V Salomaa, L Peltonen, M Orho-Melander, JM Ordovas, M Boehnke, GR Abecasis, KL Mohlke, LA Cupples
Hippocampus Gene Expression Correlates for ENTRIES_CLOSED measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The ENTRIES_CLOSED measures Number of entries into closed arms of plus maze under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for OF_HAB_RATIO measured in BXD RI Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The OF_HAB_RATIO measures Open Field - Habituation ratio (First:Last intervals) under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for MDMA_ACT_SAL_2 measured in BXD RI Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The MDMA_ACT_SAL_2 measures Locomotor activity after second saline treatment. under the domain MDMA. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for VERCNT165 measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The VERCNT165 measures Morphine vertical activity counts minutes 150-165 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for PCT_ENTRIES_CLOSED measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The PCT_ENTRIES_CLOSED measures Percentage of entries into closed arms of plus maze under the domain Porsolt. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
cocaine related behavior 3 (Cocrb3) spans 114.482445 - 164.482445 Mbp (NCBI Build 37) on Chr 2. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
QTL for cocaine related behavior on Chr2 at D2Byu3 (139.48 Mbp , Build 37)
Description:
cocaine related behavior spans 114.48 - 164.48 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for ethanol induced locomotion on Chr2 at NA (141.12 Mbp , Build 37)
Description:
ethanol induced locomotion spans 116.12 - 166.12 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Hitzemann R, Demarest K, Koyner J, Cipp L, Patel N, Rasmussen E, McCaughran J Jr
QTL for high-dose ethanol actions on Chr2 at D2Mit21 (159.38 Mbp , Build 37)
Description:
high-dose ethanol actions spans 134.38 - 184.38 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Erwin VG, Markel PD, Johnson TE, Gehle VM, Jones BC
QTL for METH responses for climbing on Chr2 at D2Mc1 (162.34 Mbp , Build 37)
Description:
METH responses for climbing spans 137.34 - 187.34 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for nicotine sensitivity on Chr2 at D2Mit311 (162.39 Mbp , Build 37)
Description:
nicotine sensitivity spans 137.39 - 187.39 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol consumption on Chr2 at D2Mit148 (183.66 Mbp , Build 37)
Description:
alcohol consumption spans 158.66 - 208.66 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Vadasz C, Saito M, Gyetvai B, Mikics E, Vadasz C 2nd
QTL for alcohol preference locus on Chr2 at D2Mit74 (187.16 Mbp , Build 37)
Description:
alcohol preference locus spans 162.16 - 212.16 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol consumption on Chr2 at D2Mit74 (187.16 Mbp , Build 37)
Description:
alcohol consumption spans 162.16 - 212.16 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Vadasz C, Saito M, Gyetvai B, Mikics E, Vadasz C 2nd
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