Genes associated with Homo sapiens that interact with the MeSH term 'HG-7-85-01 compound' (C552521). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Heschl's gyrus morphology. The EFO term Heschl's gyrus morphology measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
DC Cai, H Fonteijn, T Guadalupe, M Zwiers, K Wittfeld, A Teumer, M Hoogman, A Arias-Vásquez, Y Yang, J Buitelaar, G Fernández, HG Brunner, H van Bokhoven, B Franke, K Hegenscheid, G Homuth, SE Fisher, HJ Grabe, C Francks, P Hagoort
QTL associated with gonadal fat pad weight QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (114084818)
QTL associated with weight gain in high growth mice 7. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (96868181)
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Hypertension. The EFO term hypertension was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
GB Ehret, PB Munroe, KM Rice, M Bochud, AD Johnson, DI Chasman, AV Smith, MD Tobin, GC Verwoert, SJ Hwang, V Pihur, P Vollenweider, PF O'Reilly, N Amin, JL Bragg-Gresham, A Teumer, NL Glazer, L Launer, JH Zhao, Y Aulchenko, S Heath, S Sõber, A Parsa, J Luan, P Arora, A Dehghan, F Zhang, G Lucas, AA Hicks, AU Jackson, JF Peden, T Tanaka, SH Wild, I Rudan, W Igl, Y Milaneschi, AN Parker, C Fava, JC Chambers, ER Fox, M Kumari, MJ Go, P van der Harst, WH Kao, M Sjögren, DG Vinay, M Alexander, Y Tabara, S Shaw-Hawkins, PH Whincup, Y Liu, G Shi, J Kuusisto, B Tayo, M Seielstad, X Sim, KD Nguyen, T Lehtimäki, G Matullo, Y Wu, TR Gaunt, NC Onland-Moret, MN Cooper, CG Platou, E Org, R Hardy, S Dahgam, J Palmen, V Vitart, PS Braund, T Kuznetsova, CS Uiterwaal, A Adeyemo, W Palmas, H Campbell, B Ludwig, M Tomaszewski, I Tzoulaki, ND Palmer, T Aspelund, M Garcia, YP Chang, JR O'Connell, NI Steinle, DE Grobbee, DE Arking, SL Kardia, AC Morrison, D Hernandez, S Najjar, WL McArdle, D Hadley, MJ Brown, JM Connell, AD Hingorani, IN Day, DA Lawlor, JP Beilby, RW Lawrence, R Clarke, JC Hopewell, H Ongen, AW Dreisbach, Y Li, JH Young, JC Bis, M Kähönen, J Viikari, LS Adair, NR Lee, MH Chen, M Olden, C Pattaro, JA Bolton, A Köttgen, S Bergmann, V Mooser, N Chaturvedi, TM Frayling, M Islam, TH Jafar, J Erdmann, SR Kulkarni, SR Bornstein, J Grässler, L Groop, BF Voight, J Kettunen, P Howard, A Taylor, S Guarrera, F Ricceri, V Emilsson, A Plump, I Barroso, KT Khaw, AB Weder, SC Hunt, YV Sun, RN Bergman, FS Collins, LL Bonnycastle, LJ Scott, HM Stringham, L Peltonen, M Perola, E Vartiainen, SM Brand, JA Staessen, TJ Wang, PR Burton, M Soler Artigas, Y Dong, H Snieder, X Wang, H Zhu, KK Lohman, ME Rudock, SR Heckbert, NL Smith, KL Wiggins, A Doumatey, D Shriner, G Veldre, M Viigimaa, S Kinra, D Prabhakaran, V Tripathy, CD Langefeld, A Rosengren, DS Thelle, AM Corsi, A Singleton, T Forrester, G Hilton, CA McKenzie, T Salako, N Iwai, Y Kita, T Ogihara, T Ohkubo, T Okamura, H Ueshima, S Umemura, S Eyheramendy, T Meitinger, HE Wichmann, YS Cho, HL Kim, JY Lee, J Scott, JS Sehmi, W Zhang, B Hedblad, P Nilsson, GD Smith, A Wong, N Narisu, A Stančáková, LJ Raffel, J Yao, S Kathiresan, CJ O'Donnell, SM Schwartz, MA Ikram, WT Longstreth, TH Mosley, S Seshadri, NR Shrine, LV Wain, MA Morken, AJ Swift, J Laitinen, I Prokopenko, P Zitting, JA Cooper, SE Humphries, J Danesh, A Rasheed, A Goel, A Hamsten, H Watkins, SJ Bakker, WH van Gilst, CS Janipalli, KR Mani, CS Yajnik, A Hofman, FU Mattace-Raso, BA Oostra, A Demirkan, A Isaacs, F Rivadeneira, EG Lakatta, M Orru, A Scuteri, M Ala-Korpela, AJ Kangas, LP Lyytikäinen, P Soininen, T Tukiainen, P Würtz, RT Ong, M Dörr, HK Kroemer, U Völker, H Völzke, P Galan, S Hercberg, M Lathrop, D Zelenika, P Deloukas, M Mangino, TD Spector, G Zhai, JF Meschia, MA Nalls, P Sharma, J Terzic, MV Kumar, M Denniff, E Zukowska-Szczechowska, LE Wagenknecht, FG Fowkes, FJ Charchar, PE Schwarz, C Hayward, X Guo, C Rotimi, ML Bots, E Brand, NJ Samani, O Polasek, PJ Talmud, F Nyberg, D Kuh, M Laan, K Hveem, LJ Palmer, YT van der Schouw, JP Casas, KL Mohlke, P Vineis, O Raitakari, SK Ganesh, TY Wong, ES Tai, RS Cooper, M Laakso, DC Rao, TB Harris, RW Morris, AF Dominiczak, M Kivimaki, MG Marmot, T Miki, D Saleheen, GR Chandak, J Coresh, G Navis, V Salomaa, BG Han, X Zhu, JS Kooner, O Melander, PM Ridker, S Bandinelli, UB Gyllensten, AF Wright, JF Wilson, L Ferrucci, M Farrall, J Tuomilehto, PP Pramstaller, R Elosua, N Soranzo, EJ Sijbrands, D Altshuler, RJ Loos, AR Shuldiner, C Gieger, P Meneton, AG Uitterlinden, NJ Wareham, V Gudnason, JI Rotter, R Rettig, M Uda, DP Strachan, JC Witteman, AL Hartikainen, JS Beckmann, E Boerwinkle, RS Vasan, M Boehnke, MG Larson, MR Järvelin, BM Psaty, GR Abecasis, A Chakravarti, P Elliott, CM van Duijn, C Newton-Cheh, D Levy, MJ Caulfield, T Johnson
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "detoxification of mercury ion", which is defined as "Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0])." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "detoxification of mercury ion", which is defined as "Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0])." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "detoxification of mercury ion", which is defined as "Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0])." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "detoxification of mercury ion", which is defined as "Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0])." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "detoxification of mercury ion", which is defined as "Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0])." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Orthostatic hypotension. The EFO term orthostatic hypotension was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "phytochelatin biosynthetic process", which is defined as "The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "phytochelatin metabolic process", which is defined as "The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "phytochelatin biosynthetic process", which is defined as "The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "phytochelatin metabolic process", which is defined as "The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "mercury ion binding", which is defined as "Interacting selectively and non-covalently with mercury (Hg) ions." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "mercury ion binding", which is defined as "Interacting selectively and non-covalently with mercury (Hg) ions." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "mercury ion transport", which is defined as "The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
QTL associated with femur length in high growth mice 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (76866991)
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