QTL associated with experimental allergic encephalomyelitis susceptibility 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (41438808)
Authors:
Teuscher C, Doerge RW, Fillmore PD, Blankenhorn EP
QTL associated with plasmacytoma susceptibility 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (55545184)
Ethanol Induced Ataxia Chr#17 rs3672987(33247165) with right flanking marker rs4136382(3388912) and left marker rs3715723(58810428). This was mapped in 300 + (b6x129)F2 mice.
QTL associated with cocaine induced activation 13. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (47859524)
QTL associated with hepatocarcinogenesis in females 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (34380179)
QTL associated with Angiostrongylus costaricensis nematode susceptibility 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (34380179)
QTL associated with SGC/Knj cross B6 QTL 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (34380179)
Authors:
Hamano Y, Tsukamoto K, Abe M, Sun GD, Zhang D, Fujii H, Matsuoka S, Tanaka M, Ishida-Okawara A, Tachikawa H, Nishimura H, Tokunaka K, Hirose S, Suzuki K
QTL associated with total body bone mineral density 7. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (31979623)
Authors:
Masinde GL, Li X, Gu W, Wergedal J, Mohan S, Baylink DJ
QTL for t-psl on Chr17 at Hp (53.97 Mbp , Build 37)
Description:
t-psl spans 28.97 - 78.97 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL associated with cerebral malaria susceptibility in CBA/N. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (34137861)
QTL associated with CD86 expression in activated macrophages. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (57366870)
Authors:
Karlsson J, Johannesson M, Lindvall T, Wernhoff P, Holmdahl R, Andersson A
QTL associated with gastritis type A susceptibility locus 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (44392666)
Authors:
Baxter AG, Jordan MA, Silveira PA, Wilson WE, Van Driel IR
QTL associated with insulin dependent diabetes susceptibility 16. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (33737692)
QTL associated with ventral midbrain iron content 9. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (45448429)
Authors:
Jones LC, McCarthy KA, Beard JL, Keen CL, Jones BC
Differential gene expression in nucleus accumbens somatostatin interneurons_cocaine_mice_pvalue
Description:
To characterize transcriptional alterations that cocaine induces in these cells, we perform cell type-specific RNA-sequencing on FACS-isolated nuclei of somatostatin interneurons and identified 1100 DETs enriched for processes related to neural plasticity. To profile the entire (non poly-A selected) transcriptome of NAc somatostatin interneurons, we generated a transgenic reporter line (SST-TLG498 mice) to label the nuclei of these cells with a modified form of EGFP that is retained in the nuclear membrane (EGFP-F)22, enabling their isolation from NAc dissections using FACS. We succeeded in FACS-isolating nuclei suitable for RNA-sequencing from individual SST-TLG498 mice. We proceeded with differential expression analysis of the RNA-sequencing data to identify differentially expressed transcripts (DETs) in NAc somatostatin interneurons in response to repeated cocaine exposure: 778 transcripts were upregulated by cocaine and 322 were downregulated.
Authors:
Efrain A Ribeiro, Marine Salery, Joseph R Scarpa, Erin S Calipari, Peter J Hamilton, Stacy M Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie Doyle, Casey Lardner, Dominicka Burek, Ana Strat, Stephen Pirpinias, Ezekiell Mouzon, Ming-Hu Han, Rachael L Neve, Rosemary C Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J Nestler
QTL associated with circulating hormone level QTL 8. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (25502885)
Authors:
Harper JM, Galecki AT, Burke DT, Pinkosky SL, Miller RA
Here, female High Drinking in the Dark (HDID) mice were stereotaxically injected with 0.5uL rAAV2/5-CMV-Cre-GFP and 0.5uL rAAV2-hSyn-DIO-hM3Dq-mCherry bilaterally into the NAc. A Drinking in the Dark (DID) experiment lasting 6 weeks was carried out with 2 fluid groups (water or ethanol) and 2 treatment groups (VEH/VEH/VEH or VEH/CNO/VEH). Mice were serially treated with vehicle prior to DID during week 1 to establish baseline drinking, CNO (1mg/kg) during weeks 2-5 to measure the effects of chronic treatment, and then mice were treated with vehicle again during week 6 to determine if there were any lasting effects of chronic CNO treatment. This gene set comprises 2,377 genes that were differentially expressed in the nucleus accumbens of ethanol drinking HDID mice treated with CNO as compared to the water drinking and vehicle treated control group.
Authors:
Darya Y. Pozhidayeva, Sean P. Farris, Calla M. Goeke, Evan J. Firsick, Kayla G. Townsley, Marina Guizzetti, and Angela R. Ozburn
QTL for differences in cocaine responsiveness on Chr17 at Ck-2 (45.25 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 20.25 - 70.25 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL associated with anticardiolipin antibody 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (33737692)
Authors:
Ida A, Hirose S, Hamano Y, Kodera S, Jiang Y, Abe M, Zhang D, Nishimura H, Shirai T
Add Selected GeneSets to Project(s)
Warning: You are not signed in. Adding these genesets to a project will create a guest account for you.
Guest accounts are temporary, and will be removed within 24 hours of creation. Guest accounts can be registered as full accounts, but you cannot associate a guest account with an existing account.
If you already have an account, you should sign into that account before proceeding.