QTL for ethanol withdrawal on Chr15 at D15Ncvs19 (0.00 Mbp , Build 37)
Description:
ethanol withdrawal spans 0.00 - 25.00 Mbp (NCBI Build 37) on Chr15. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for high-dose ethanol actions on Chr15 at D15Mit12 (12.77 Mbp , Build 37)
Description:
high-dose ethanol actions spans 0.00 - 37.77 Mbp (NCBI Build 37) on Chr15. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Erwin VG, Markel PD, Johnson TE, Gehle VM, Jones BC
Acute and chronic alcohol exposure was analyzed in 534 (C57BL/6J x C3H/HeJ)F2 mice. Behavioral testing was done using 5 traits, acute drug effect, forced ethanol drinking, withdrawal studies ethanol preference and stress induced ethanol drinking. The following QTL were found in a genome wide scan: Following the QTL is the Chromosome , cM location, and LOD score, Eih1 (Chr 1, 85 cM, LOD 6.6), Eih2 (Chr 7, 10 cM, LOD 3.6), Ceih1 (Chr 3, 55 cM, LOD 4.1), Ceih2 (Chr 6, 24.7 cM, LOD 4.1), Ceih3 (Chr 13, 39 cM, LOD 4.1), Eia1(Chr 1, 65 cM, LOD 10.3 and 10.4), Eiwa1 (Chr 7, 50 cM, LOD 4.4), Eiwa2(Chr 11, 43.1 cM, LOD 4.1),Aldd1(Chr 5, 42 cM, LOD 13.2), Aldd2(Chr 12, 18 cM, LOD 5.3),Eiwax1(Chr 1, 79 cM, LOD 6.5), Eiwax2(Chr 5, 59 cM, LOD 15.0), Eiwax3(Chr 12, 21 cM, LOD 3.6), Methp1(Chr 16, 31.4 cM, LOD 4.3), Mec1(Chr 16, 19.4 cM, LOD 5.1), Epbs1(Chr 16, 33 cM, LOD 4.1), Ecbs1(Chr 16, 29.4 cM, LOD 4.8), Mec2(Chr 1, 109 cM, LOD 3.9), Mec3(Chr 2, 109 cM, LOD 4.3), Mec4(Chr 5, 29 cM, LOD 3.9), Mec5(Chr 10, 2 cM, LOD 5.0), Mec6(Chr 15, 49 cM, LOD 5.2, 95% CI 6.7–56.7).
Authors:
Drews E, Rcz I, Lacava AD, Barth A, Bilkei-Gorz A, Wienker TF, Zimmer A
Analysis of 2 Lore5 interval specific congenic strains (ISCS) excluded Mapk8ip as a candidate gene for Lore5. The Lore5 interval appears to be localized between D15Mit94 (29 cM) and D15Mit93 (43.7).
Authors:
Ehringer MA, Thompson J, Conroy O, Yang F, Hink R, Bennett B, Johnson TE, Sikela JM
QTL associated with angiogenesis due to FGF2 QTL 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (52944065)
QTL associated with accelerator of polyoma-induced mammary tumors 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (56068554)
Authors:
Cozma D, Lukes L, Rouse J, Qiu TH, Liu ET, Hunter KW
QTL associated with circulating hormone level QTL 7. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (50972844)
Authors:
Harper JM, Galecki AT, Burke DT, Pinkosky SL, Miller RA
QTL associated with directional asymmetry QTL 12. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (43279930)
Authors:
Kosarov M, Havelkov H, Krulov M, Demant P, Lipoldov M
QTL associated with directional asymmetry QTL 13. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (43279930)
Authors:
Kosarov M, Havelkov H, Krulov M, Demant P, Lipoldov M
QTL associated with "early growth rate, direct effect 2". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (43279930)
QTL associated with heart rate quantitative locus 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (56068554)
Authors:
Sugiyama F, Churchill GA, Li R, Libby LJ, Carver T, Yagami K, John SW, Paigen B
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