The chromosome 1 region has peak markers with of LOD of 3.45 and 3.46 for Alcoholism gender age and constraint as D1S2878 (165403366) D1S196 (167604128). Arbitrary interval of 25 MBp on each side of the peak makers was uploaded.
Authors:
Hill SY, Shen S, Zezza N, Hoffman EK, Perlin M, Allan W
The total transcriptome including genes that are differentially expressed in cocaine addicts compared to control subjects. Post-mortem brain samples were collected from the dorsolateral prefrontal cortex (dlPFC) of the cocaine addict group and the control group. To assess gene expression, RNA-seq was performed. Data taken from Supplementary Table 2. Values presented are k.diff values. Data available from GEO with accession number GSE99349."
Authors:
Efrain A Ribeiro, Joseph R Scarpa, Susanna P Garamszegi, Andrew Kasarskis, Deborah C Mash, Eric J Nestler
Data from GEO GSE194368 and analyzed using GEO2R, only top gene shown. Authors identified transcriptional adaptations of GR signaling in the amygdala of humans with OUD. Thus, GRs, their coregulators and downstream systems may represent viable therapeutic targets to treat the “stress side” of OUD.
Authors:
Stephanie A Carmack, Janaina C M Vendruscolo, M Adrienne McGinn, Jorge Miranda-Barrientos, Vez Repunte-Canonigo, Gabriel D Bosse, Daniele Mercatelli, Federico M Giorgi, Yu Fu, Anthony J Hinrich, Francine M Jodelka, Karen Ling, Robert O Messing, Randall T Peterson, Frank Rigo, Scott Edwards, Pietro P Sanna, Marisela Morales, Michelle L Hastings, George F Koob, Leandro F Vendruscolo
Cerebellum Gene Expression Correlates for TAILCLIP_LAT_SEC measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The TAILCLIP_LAT_SEC measures Mechanical Nociception - Tail Clip Test under the domain Pain. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for TAILCLIP_LAT_SEC measured in BXD RI Females & Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The TAILCLIP_LAT_SEC measures Mechanical Nociception - Tail Clip Test under the domain Pain. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for OF_DIST_5_10 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The OF_DIST_5_10 measures Open Field - Total distance traveled 5-10 minutes under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for ROTAETHA_DIFF measured in BXD RI Females & Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The ROTAETHA_DIFF measures Difference in time on rotarod between training and ethanol under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for OF_REAR_0_5 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The OF_REAR_0_5 measures Open Field - Total rears 0-5 minutes under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for OF_REAR_5_10 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The OF_REAR_5_10 measures Open Field - Total rears 5-10 minutes under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for high-dose ethanol actions on Chr3 at D3Mit21 (39.41 Mbp , Build 37)
Description:
high-dose ethanol actions spans 14.41 - 64.41 Mbp (NCBI Build 37) on Chr3. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Erwin VG, Markel PD, Johnson TE, Gehle VM, Jones BC
QTL for METH responses for home cage activity on Chr3 at Il2 (39.85 Mbp , Build 37)
Description:
METH responses for home cage activity spans 14.85 - 64.85 Mbp (NCBI Build 37) on Chr3. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for ethanol conditioned taste aversion on Chr3 at D3Mc1 (47.70 Mbp , Build 37)
Description:
ethanol conditioned taste aversion spans 22.70 - 72.70 Mbp (NCBI Build 37) on Chr3. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for ethanol withdrawal on Chr3 at D3Mc1 (47.70 Mbp , Build 37)
Description:
ethanol withdrawal spans 22.70 - 72.70 Mbp (NCBI Build 37) on Chr3. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL associated with arthropathy in MRL and DBA/1 mice 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (57246565)
Authors:
Oishi H, Miyazaki T, Mizuki S, Kamogawa J, Lu LM, Tsubaki T, Arita N, Ono M, Yamamoto H, Nose M
QTL associated with circulating hormone level QTL 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (56600603)
Authors:
Harper JM, Galecki AT, Burke DT, Pinkosky SL, Miller RA
QTL associated with collagen induced arthritis QTL 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (82943273)
Authors:
Johannesson M, Olsson LM, Lindqvist AK, Mller S, Koczan D, Wester-Rosenlf L, Thiesen HJ, Ibrahim S, Holmdahl R
QTL associated with epistatic circling A C57L/J 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (82366294)
Authors:
Cryns K, Van Spaendonck MP, Flothmann K, van Alphen AM, Van De Heyning PH, Timmermans JP, De Zeeuw CI, Van Camp G
QTL associated with insulin dependent diabetes susceptibility 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (60270627)
Authors:
Moritoki Y, Tsuda M, Tsuneyama K, Zhang W, Yoshida K, Lian ZX, Yang GX, Ridgway WM, Wicker LS, Ansari AA, Gershwin ME
QTL associated with inspiratory timing at baseline QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (51563737)
Authors:
Tankersley CG, DiSilvestre DA, Jedlicka AE, Wilkins HM, Zhang L
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