QTL for METH responses for climbing on Chr4 at Mltr3 (34.50 Mbp , Build 37)
Description:
METH responses for climbing spans 9.50 - 59.50 Mbp (NCBI Build 37) on Chr4. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term '(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine' (C516138). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'butyraldehyde' (C018475). Incorporates data from 7 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Equus caballus that interact with the MeSH term 'Castor Oil' (D002368). Incorporates data from 887 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Gadus morhua that interact with the MeSH term 'methylmercuric chloride' (C004925). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide' (C459179). Incorporates data from 9 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Valproic Acid' (D014635). Incorporates data from 1238 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Lead' (D007854). Incorporates data from 23 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Grape Seed Proanthocyanidins' (C511402). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Catechin' (D002392). Incorporates data from 12 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '2,3-dimethylhydroquinone' (C516077). Incorporates data from 6043 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Methyl Methanesulfonate' (D008741). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Lewis rats operantly self-administer drugs of abuse including nicotine, whereas Fisher self-administer poorly. Lewis vs Fischer Ratio shown. Laser capture microdissection was used to obtain nucleus accumbens shell GABA neurons project to ventral pallidum labeled by Fluorogold. The gene expression profiles of these neurons were obtained using Affymetrix Rat Gene ST 1.0 microarrays. A total of 322 genes were differentially expressed at a Lewis vs Fisher ratio of >1.5-fold (P < 0.05 and FDR < 5%).
Authors:
Sharp BM, Chen H, Gong S, Wu X, Liu Z, Hiler K, Taylor WL, Matta SG
Average rotarod training latency Chr# 4 rs13477617(26886337) with right flanking marker rs3660863(7127435) and left marker rs3684104 (38269953). This was mapped in 300 + (b6x129)F2 mice.
QTL associated with "alcohol preference locus 7, male specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (34342409)
QTL associated with "alcohol preference locus 8, female specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (34342409)
QTL associated with angiogenesis due to FGF2 QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (32254939)
QTL associated with keratinocyte stem cell locus 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (9322672)
QTL associated with salmonella enteritidis susceptibility 8. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (25610387)
QTL associated with weight 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (9927643)
Authors:
Bennett B, Carosone-Link PJ, Lu L, Chesler EJ, Johnson TE
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