List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Cholesterol, total. The EFO term total cholesterol measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
TM Teslovich, K Musunuru, AV Smith, AC Edmondson, IM Stylianou, M Koseki, JP Pirruccello, S Ripatti, DI Chasman, CJ Willer, CT Johansen, SW Fouchier, A Isaacs, GM Peloso, M Barbalic, SL Ricketts, JC Bis, YS Aulchenko, G Thorleifsson, MF Feitosa, J Chambers, M Orho-Melander, O Melander, T Johnson, X Li, X Guo, M Li, Y Shin Cho, M Jin Go, Y Jin Kim, JY Lee, T Park, K Kim, X Sim, R Twee-Hee Ong, DC Croteau-Chonka, LA Lange, JD Smith, K Song, J Hua Zhao, X Yuan, J Luan, C Lamina, A Ziegler, W Zhang, RY Zee, AF Wright, JC Witteman, JF Wilson, G Willemsen, HE Wichmann, JB Whitfield, DM Waterworth, NJ Wareham, G Waeber, P Vollenweider, BF Voight, V Vitart, AG Uitterlinden, M Uda, J Tuomilehto, JR Thompson, T Tanaka, I Surakka, HM Stringham, TD Spector, N Soranzo, JH Smit, J Sinisalo, K Silander, EJ Sijbrands, A Scuteri, J Scott, D Schlessinger, S Sanna, V Salomaa, J Saharinen, C Sabatti, A Ruokonen, I Rudan, LM Rose, R Roberts, M Rieder, BM Psaty, PP Pramstaller, I Pichler, M Perola, BW Penninx, NL Pedersen, C Pattaro, AN Parker, G Pare, BA Oostra, CJ O'Donnell, MS Nieminen, DA Nickerson, GW Montgomery, T Meitinger, R McPherson, MI McCarthy, W McArdle, D Masson, NG Martin, F Marroni, M Mangino, PK Magnusson, G Lucas, R Luben, RJ Loos, ML Lokki, G Lettre, C Langenberg, LJ Launer, EG Lakatta, R Laaksonen, KO Kyvik, F Kronenberg, IR König, KT Khaw, J Kaprio, LM Kaplan, A Johansson, MR Jarvelin, AC Janssens, E Ingelsson, W Igl, G Kees Hovingh, JJ Hottenga, A Hofman, AA Hicks, C Hengstenberg, IM Heid, C Hayward, AS Havulinna, ND Hastie, TB Harris, T Haritunians, AS Hall, U Gyllensten, C Guiducci, LC Groop, E Gonzalez, C Gieger, NB Freimer, L Ferrucci, J Erdmann, P Elliott, KG Ejebe, A Döring, AF Dominiczak, S Demissie, P Deloukas, EJ de Geus, U de Faire, G Crawford, FS Collins, YD Chen, MJ Caulfield, H Campbell, NP Burtt, LL Bonnycastle, DI Boomsma, SM Boekholdt, RN Bergman, I Barroso, S Bandinelli, CM Ballantyne, TL Assimes, T Quertermous, D Altshuler, M Seielstad, TY Wong, ES Tai, AB Feranil, CW Kuzawa, LS Adair, HA Taylor, IB Borecki, SB Gabriel, JG Wilson, H Holm, U Thorsteinsdottir, V Gudnason, RM Krauss, KL Mohlke, JM Ordovas, PB Munroe, JS Kooner, AR Tall, RA Hegele, JJ Kastelein, EE Schadt, JI Rotter, E Boerwinkle, DP Strachan, V Mooser, K Stefansson, MP Reilly, NJ Samani, H Schunkert, LA Cupples, MS Sandhu, PM Ridker, DJ Rader, CM van Duijn, L Peltonen, GR Abecasis, M Boehnke, S Kathiresan
GWAS: low density lipoprotein cholesterol measurement
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was LDL cholesterol. The EFO term low density lipoprotein cholesterol measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
TM Teslovich, K Musunuru, AV Smith, AC Edmondson, IM Stylianou, M Koseki, JP Pirruccello, S Ripatti, DI Chasman, CJ Willer, CT Johansen, SW Fouchier, A Isaacs, GM Peloso, M Barbalic, SL Ricketts, JC Bis, YS Aulchenko, G Thorleifsson, MF Feitosa, J Chambers, M Orho-Melander, O Melander, T Johnson, X Li, X Guo, M Li, Y Shin Cho, M Jin Go, Y Jin Kim, JY Lee, T Park, K Kim, X Sim, R Twee-Hee Ong, DC Croteau-Chonka, LA Lange, JD Smith, K Song, J Hua Zhao, X Yuan, J Luan, C Lamina, A Ziegler, W Zhang, RY Zee, AF Wright, JC Witteman, JF Wilson, G Willemsen, HE Wichmann, JB Whitfield, DM Waterworth, NJ Wareham, G Waeber, P Vollenweider, BF Voight, V Vitart, AG Uitterlinden, M Uda, J Tuomilehto, JR Thompson, T Tanaka, I Surakka, HM Stringham, TD Spector, N Soranzo, JH Smit, J Sinisalo, K Silander, EJ Sijbrands, A Scuteri, J Scott, D Schlessinger, S Sanna, V Salomaa, J Saharinen, C Sabatti, A Ruokonen, I Rudan, LM Rose, R Roberts, M Rieder, BM Psaty, PP Pramstaller, I Pichler, M Perola, BW Penninx, NL Pedersen, C Pattaro, AN Parker, G Pare, BA Oostra, CJ O'Donnell, MS Nieminen, DA Nickerson, GW Montgomery, T Meitinger, R McPherson, MI McCarthy, W McArdle, D Masson, NG Martin, F Marroni, M Mangino, PK Magnusson, G Lucas, R Luben, RJ Loos, ML Lokki, G Lettre, C Langenberg, LJ Launer, EG Lakatta, R Laaksonen, KO Kyvik, F Kronenberg, IR König, KT Khaw, J Kaprio, LM Kaplan, A Johansson, MR Jarvelin, AC Janssens, E Ingelsson, W Igl, G Kees Hovingh, JJ Hottenga, A Hofman, AA Hicks, C Hengstenberg, IM Heid, C Hayward, AS Havulinna, ND Hastie, TB Harris, T Haritunians, AS Hall, U Gyllensten, C Guiducci, LC Groop, E Gonzalez, C Gieger, NB Freimer, L Ferrucci, J Erdmann, P Elliott, KG Ejebe, A Döring, AF Dominiczak, S Demissie, P Deloukas, EJ de Geus, U de Faire, G Crawford, FS Collins, YD Chen, MJ Caulfield, H Campbell, NP Burtt, LL Bonnycastle, DI Boomsma, SM Boekholdt, RN Bergman, I Barroso, S Bandinelli, CM Ballantyne, TL Assimes, T Quertermous, D Altshuler, M Seielstad, TY Wong, ES Tai, AB Feranil, CW Kuzawa, LS Adair, HA Taylor, IB Borecki, SB Gabriel, JG Wilson, H Holm, U Thorsteinsdottir, V Gudnason, RM Krauss, KL Mohlke, JM Ordovas, PB Munroe, JS Kooner, AR Tall, RA Hegele, JJ Kastelein, EE Schadt, JI Rotter, E Boerwinkle, DP Strachan, V Mooser, K Stefansson, MP Reilly, NJ Samani, H Schunkert, LA Cupples, MS Sandhu, PM Ridker, DJ Rader, CM van Duijn, L Peltonen, GR Abecasis, M Boehnke, S Kathiresan
Whole brain expression correlates of ethanol withdrawal in BXD RI mice based on phenotype data in the 1997 Buck et al manuscript. Expression correlates were generated using GeneNetwork.org
Hippocampus Gene Expression Correlates for LM_ALT_CONTEXT measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The LM_ALT_CONTEXT measures Activity in altered context in fear conditioning apparatus under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for NX_ADIST_3 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The NX_ADIST_3 measures Naloxone induced Morphine Withdrawal TOTAL vertical activity counts in 15 minutes under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Genes associated with Homo sapiens that interact with the MeSH term 'Ribose' (D012266). Incorporates data from 298 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'usnic acid' (C073339). Incorporates data from 5 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Deoxyadenosines' (D003839). Incorporates data from 73 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Cholesterol' (D002784). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one' (C093973). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Cholic Acid' (D019826). Incorporates data from 31 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Mesocricetus auratus that interact with the MeSH term 'Cholesterol, Dietary' (D002791). Incorporates data from 128 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Cholates' (D020355). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '2-arachidonylglycerol' (C094503). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Colinus virginianus that interact with the MeSH term '2,6-dinitrotoluene' (C023514). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Sus scrofa that interact with the MeSH term 'Dietary Fats' (D004041). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'hyperforin' (C001654). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Cricetulus griseus that interact with the MeSH term 'Endosulfan' (D004726). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Chenodeoxycholic Acid' (D002635). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'rosiglitazone' (C089730). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Authors:
None
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