List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Blood pressure. The EFO term mean arterial pressure was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
TN Kelly, F Takeuchi, Y Tabara, TL Edwards, YJ Kim, P Chen, H Li, Y Wu, CF Yang, Y Zhang, D Gu, T Katsuya, T Ohkubo, YT Gao, MJ Go, YY Teo, L Lu, NR Lee, LC Chang, H Peng, Q Zhao, E Nakashima, Y Kita, XO Shu, NH Kim, ES Tai, Y Wang, LS Adair, CH Chen, S Zhang, C Li, T Nabika, S Umemura, Q Cai, YS Cho, TY Wong, J Zhu, JY Wu, X Gao, JE Hixson, H Cai, J Lee, CY Cheng, DC Rao, YB Xiang, MC Cho, BG Han, A Wang, FJ Tsai, K Mohlke, X Lin, MK Ikram, JY Lee, W Zheng, M Tetsuro, N Kato, J He
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Systolic blood pressure. The EFO term systolic blood pressure was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
C Newton-Cheh, T Johnson, V Gateva, MD Tobin, M Bochud, L Coin, SS Najjar, JH Zhao, SC Heath, S Eyheramendy, K Papadakis, BF Voight, LJ Scott, F Zhang, M Farrall, T Tanaka, C Wallace, JC Chambers, KT Khaw, P Nilsson, P van der Harst, S Polidoro, DE Grobbee, NC Onland-Moret, ML Bots, LV Wain, KS Elliott, A Teumer, J Luan, G Lucas, J Kuusisto, PR Burton, D Hadley, WL McArdle, M Brown, A Dominiczak, SJ Newhouse, NJ Samani, J Webster, E Zeggini, JS Beckmann, S Bergmann, N Lim, K Song, P Vollenweider, G Waeber, DM Waterworth, X Yuan, L Groop, M Orho-Melander, A Allione, A Di Gregorio, S Guarrera, S Panico, F Ricceri, V Romanazzi, C Sacerdote, P Vineis, I Barroso, MS Sandhu, RN Luben, GJ Crawford, P Jousilahti, M Perola, M Boehnke, LL Bonnycastle, FS Collins, AU Jackson, KL Mohlke, HM Stringham, TT Valle, CJ Willer, RN Bergman, MA Morken, A Döring, C Gieger, T Illig, T Meitinger, E Org, A Pfeufer, HE Wichmann, S Kathiresan, J Marrugat, CJ O'Donnell, SM Schwartz, DS Siscovick, I Subirana, NB Freimer, AL Hartikainen, MI McCarthy, PF O'Reilly, L Peltonen, A Pouta, PE de Jong, H Snieder, WH van Gilst, R Clarke, A Goel, A Hamsten, JF Peden, U Seedorf, AC Syvänen, G Tognoni, EG Lakatta, S Sanna, P Scheet, D Schlessinger, A Scuteri, M Dörr, F Ernst, SB Felix, G Homuth, R Lorbeer, T Reffelmann, R Rettig, U Völker, P Galan, IG Gut, S Hercberg, GM Lathrop, D Zelenika, P Deloukas, N Soranzo, FM Williams, G Zhai, V Salomaa, M Laakso, R Elosua, NG Forouhi, H Völzke, CS Uiterwaal, YT van der Schouw, ME Numans, G Matullo, G Navis, G Berglund, SA Bingham, JS Kooner, JM Connell, S Bandinelli, L Ferrucci, H Watkins, TD Spector, J Tuomilehto, D Altshuler, DP Strachan, M Laan, P Meneton, NJ Wareham, M Uda, MR Jarvelin, V Mooser, O Melander, RJ Loos, P Elliott, GR Abecasis, M Caulfield, PB Munroe
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Systolic blood pressure. The EFO term systolic blood pressure was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
D Levy, GB Ehret, K Rice, GC Verwoert, LJ Launer, A Dehghan, NL Glazer, AC Morrison, AD Johnson, T Aspelund, Y Aulchenko, T Lumley, A Köttgen, RS Vasan, F Rivadeneira, G Eiriksdottir, X Guo, DE Arking, GF Mitchell, FU Mattace-Raso, AV Smith, K Taylor, RB Scharpf, SJ Hwang, EJ Sijbrands, J Bis, TB Harris, SK Ganesh, CJ O'Donnell, A Hofman, JI Rotter, J Coresh, EJ Benjamin, AG Uitterlinden, G Heiss, CS Fox, JC Witteman, E Boerwinkle, TJ Wang, V Gudnason, MG Larson, A Chakravarti, BM Psaty, CM van Duijn
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Systolic blood pressure. The EFO term systolic blood pressure was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
X Lu, L Wang, X Lin, J Huang, C Charles Gu, M He, H Shen, J He, J Zhu, H Li, JE Hixson, T Wu, J Dai, L Lu, C Shen, S Chen, L He, Z Mo, Y Hao, X Mo, X Yang, J Li, J Cao, J Chen, Z Fan, Y Li, L Zhao, H Li, F Lu, C Yao, L Yu, L Xu, J Mu, X Wu, Y Deng, D Hu, W Zhang, X Ji, D Guo, Z Guo, Z Zhou, Z Yang, R Wang, J Yang, X Zhou, W Yan, N Sun, P Gao, D Gu
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Hypertension. The EFO term hypertension was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
X Lu, L Wang, X Lin, J Huang, C Charles Gu, M He, H Shen, J He, J Zhu, H Li, JE Hixson, T Wu, J Dai, L Lu, C Shen, S Chen, L He, Z Mo, Y Hao, X Mo, X Yang, J Li, J Cao, J Chen, Z Fan, Y Li, L Zhao, H Li, F Lu, C Yao, L Yu, L Xu, J Mu, X Wu, Y Deng, D Hu, W Zhang, X Ji, D Guo, Z Guo, Z Zhou, Z Yang, R Wang, J Yang, X Zhou, W Yan, N Sun, P Gao, D Gu
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Diastolic blood pressure. The EFO term diastolic blood pressure was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
X Lu, L Wang, X Lin, J Huang, C Charles Gu, M He, H Shen, J He, J Zhu, H Li, JE Hixson, T Wu, J Dai, L Lu, C Shen, S Chen, L He, Z Mo, Y Hao, X Mo, X Yang, J Li, J Cao, J Chen, Z Fan, Y Li, L Zhao, H Li, F Lu, C Yao, L Yu, L Xu, J Mu, X Wu, Y Deng, D Hu, W Zhang, X Ji, D Guo, Z Guo, Z Zhou, Z Yang, R Wang, J Yang, X Zhou, W Yan, N Sun, P Gao, D Gu
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Blood pressure. The EFO term pulse pressure measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
TN Kelly, F Takeuchi, Y Tabara, TL Edwards, YJ Kim, P Chen, H Li, Y Wu, CF Yang, Y Zhang, D Gu, T Katsuya, T Ohkubo, YT Gao, MJ Go, YY Teo, L Lu, NR Lee, LC Chang, H Peng, Q Zhao, E Nakashima, Y Kita, XO Shu, NH Kim, ES Tai, Y Wang, LS Adair, CH Chen, S Zhang, C Li, T Nabika, S Umemura, Q Cai, YS Cho, TY Wong, J Zhu, JY Wu, X Gao, JE Hixson, H Cai, J Lee, CY Cheng, DC Rao, YB Xiang, MC Cho, BG Han, A Wang, FJ Tsai, K Mohlke, X Lin, MK Ikram, JY Lee, W Zheng, M Tetsuro, N Kato, J He
QTL for METH responses for body temperature on Chr19 at Lpc1 (23.27 Mbp , Build 37)
Description:
METH responses for body temperature spans 0.00 - 48.27 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol preference locus on Chr19 at D19Mit46 (29.54 Mbp , Build 37)
Description:
alcohol preference locus spans 4.54 - 54.54 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol preference locus on Chr19 at D19Mit46 (29.54 Mbp , Build 37)
Description:
alcohol preference locus spans 4.54 - 54.54 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Chronic cocaine - Cocaine-paired (conditioned place preference) vs. Control (saline or cocaine-non-paired) DNA microarray All genes on microarray presented After the pre-conditioning phase where animals were allowed access to either compartment for 15 minutes for 4 consecutive days, the conditioning phase for the cocaine-paired groups and cocaine non-paired groups began, consisting of eight subsequent daily sessions. For both groups, cocaine (10 mg / kg) or saline injections were administered on alternate days. For the cocaine-paired groups, rats were immediately placed in one of the two compartments for 30 min with the door in place restricting a z transformation followed by z test and anova followed by Student-Newman-Keuls' post hoc test. Gene expression profile was assessed 24 h after the last conditioning session that corresponded to 48 h after last cocaine exposure, when drug has been eliminated from the body and transient transcriptional changes are likely to be minimal. Therefore, changes in gene expression at this time-point are likely to reflect longer lasting adaptations that may account for maintenance of cocaine-induced memories. The complete lists of normalized gene expression values for the hippocampus of saline-treated, cocaine non-paired and cocaine-paired groups are presented. Analyses revealed that 214 transcripts were differentially regulated in the hippocampus of cocaine-paired rats vs. non-paired and saline-treated controls. Cocaine-induced conditioned place preference caused significant increases in the expression of 151 genes and caused decreases in the expression of 63 genes. (NIF Table ID 130.1 [83])
Authors:
Krasnova IN, Li SM, Wood WH, McCoy MT, Prabhu VV, Becker KG, Katz JL, Cadet JL
Chronic cocaine - Cocaine-paired (conditioned place preference) vs. Control (saline or cocaine-non-paired) DNA microarray All genes on microarray presented After the pre-conditioning phase where animals were allowed access to either compartment for 15 minutes for 4 consecutive days, the conditioning phase for the cocaine-paired groups and cocaine non-paired groups began, consisting of eight subsequent daily sessions. For both groups, cocaine (10 mg / kg) or saline injections were administered on alternate days. For the cocaine-paired groups, rats were immediately placed in one of the two compartments for 30 min with the door in place restricting a z transformation followed by z test and anova followed by Student-Newman-Keuls' post hoc test. Gene expression profile was assessed 24 h after the last conditioning session that corresponded to 48 h after last cocaine exposure, when drug has been eliminated from the body and transient transcriptional changes are likely to be minimal. Therefore, changes in gene expression at this time-point are likely to reflect longer lasting adaptations that may account for maintenance of cocaine-induced memories. The complete lists of normalized gene expression values for the frontal cortex of saline-treated, cocaine non-paired and cocaine-paired groups are presented. Differences in the expression of 39 transcripts in the frontal cortex were related to the conditioned place preference paradigm. These include increases in the level of 22 genes and decreases in 17 genes. (NIF Table ID 130.3 [83.5])
Authors:
Krasnova IN, Li SM, Wood WH, McCoy MT, Prabhu VV, Becker KG, Katz JL, Cadet JL
Genes associated with Homo sapiens that interact with the MeSH term 'Benomyl' (D001542). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'cetrorelix' (C062876). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryzias melastigma that interact with the MeSH term '3,3'-diindolylmethane' (C016392). Incorporates data from 20 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Arsenic' (D001151). Incorporates data from 87 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one' (C093973). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '1H,1H,2H,2H-perfluorodecanol' (C033729). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
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