List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Neutrophil count. The EFO term neutrophil count was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Okada, Y Kamatani, A Takahashi, K Matsuda, N Hosono, H Ohmiya, Y Daigo, K Yamamoto, M Kubo, Y Nakamura, N Kamatani
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was C-reactive protein and white blood cell count. The EFO term leukocyte count was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was White blood cell count. The EFO term neutrophil count was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
MA Nalls, DJ Couper, T Tanaka, FJ van Rooij, MH Chen, AV Smith, D Toniolo, NA Zakai, Q Yang, A Greinacher, AR Wood, M Garcia, P Gasparini, Y Liu, T Lumley, AR Folsom, AP Reiner, C Gieger, V Lagou, JF Felix, H Völzke, NA Gouskova, A Biffi, A Döring, U Völker, S Chong, KL Wiggins, A Rendon, A Dehghan, M Moore, K Taylor, JG Wilson, G Lettre, A Hofman, JC Bis, N Pirastu, CS Fox, C Meisinger, J Sambrook, S Arepalli, M Nauck, H Prokisch, J Stephens, NL Glazer, LA Cupples, Y Okada, A Takahashi, Y Kamatani, K Matsuda, T Tsunoda, T Tanaka, M Kubo, Y Nakamura, K Yamamoto, N Kamatani, M Stumvoll, A Tönjes, I Prokopenko, T Illig, KV Patel, SF Garner, B Kuhnel, M Mangino, BA Oostra, SL Thein, J Coresh, HE Wichmann, S Menzel, J Lin, G Pistis, AG Uitterlinden, TD Spector, A Teumer, G Eiriksdottir, V Gudnason, S Bandinelli, TM Frayling, A Chakravarti, CM van Duijn, D Melzer, WH Ouwehand, D Levy, E Boerwinkle, AB Singleton, DG Hernandez, DL Longo, N Soranzo, JC Witteman, BM Psaty, L Ferrucci, TB Harris, CJ O'Donnell, SK Ganesh
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was White blood cell count. The EFO term leukocyte count was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
MA Nalls, DJ Couper, T Tanaka, FJ van Rooij, MH Chen, AV Smith, D Toniolo, NA Zakai, Q Yang, A Greinacher, AR Wood, M Garcia, P Gasparini, Y Liu, T Lumley, AR Folsom, AP Reiner, C Gieger, V Lagou, JF Felix, H Völzke, NA Gouskova, A Biffi, A Döring, U Völker, S Chong, KL Wiggins, A Rendon, A Dehghan, M Moore, K Taylor, JG Wilson, G Lettre, A Hofman, JC Bis, N Pirastu, CS Fox, C Meisinger, J Sambrook, S Arepalli, M Nauck, H Prokisch, J Stephens, NL Glazer, LA Cupples, Y Okada, A Takahashi, Y Kamatani, K Matsuda, T Tsunoda, T Tanaka, M Kubo, Y Nakamura, K Yamamoto, N Kamatani, M Stumvoll, A Tönjes, I Prokopenko, T Illig, KV Patel, SF Garner, B Kuhnel, M Mangino, BA Oostra, SL Thein, J Coresh, HE Wichmann, S Menzel, J Lin, G Pistis, AG Uitterlinden, TD Spector, A Teumer, G Eiriksdottir, V Gudnason, S Bandinelli, TM Frayling, A Chakravarti, CM van Duijn, D Melzer, WH Ouwehand, D Levy, E Boerwinkle, AB Singleton, DG Hernandez, DL Longo, N Soranzo, JC Witteman, BM Psaty, L Ferrucci, TB Harris, CJ O'Donnell, SK Ganesh
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was C-reactive protein and white blood cell count. The EFO term C-reactive protein measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was White blood cell count. The EFO term leukocyte count was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
AP Reiner, G Lettre, MA Nalls, SK Ganesh, R Mathias, MA Austin, E Dean, S Arepalli, A Britton, Z Chen, D Couper, JD Curb, CB Eaton, M Fornage, SF Grant, TB Harris, D Hernandez, N Kamatini, BJ Keating, M Kubo, A LaCroix, LA Lange, S Liu, K Lohman, Y Meng, ER Mohler, S Musani, Y Nakamura, CJ O'Donnell, Y Okada, CD Palmer, GJ Papanicolaou, KV Patel, AB Singleton, A Takahashi, H Tang, HA Taylor, K Taylor, C Thomson, LR Yanek, L Yang, E Ziv, AB Zonderman, AR Folsom, MK Evans, Y Liu, DM Becker, BM Snively, JG Wilson
Neocortex Gene Expression Correlates for AMDIST15 measured in BXD RI Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The AMDIST15 measures Morphine distance (cm) travelled minutes 0-15 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Neocortex Gene Expression Correlates for MORPH_VCOUNT_2 measured in BXD RI Females & Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The MORPH_VCOUNT_2 measures Morphine TOTAL vertical activity counts under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Heterozygote mice from a hybrid cross of C57BL/6J and FVB/NJ had heightened EtOH consumption, preference or blood EtOH concentration compared to either homozygous groups. The magnitude of dominant deviation on Chr. 11, as noted in Fig. 9, was measured after a drinking in the dark paradigm, 24hr two-bottle-choice and subsequent blood ethanol concentration measurement.
Authors:
Phillips TJ, Reed C, Burkhart-Kasch S, Li N, Hitzemann R, Yu CH, Brown LL, Helms ML, Crabbe JC, Belknap JK
To further extend these studies to a large number of genes, mRNA profiles from IL-17A- and IL-17F-stimulated cells were studied using microarrays. The expression of several cell-specific markers was analyzed to characterize the population used in the experiment. Microarray-based comparison of IL-17A- and IL-17F-induced effects alone or in combination with TNF-. RA synoviocytes were stimulated with IL-17A or IL-17F (50 ng/ml) alone or in combination with TNF- (0.5 ng/ml) for 12 h. Gene products that showed a signal intensity of 30 or greater were considered as ex- pressed and genes with a 2-fold or greater change were considered as regulated.
Authors:
Zrioual S, Ecochard R, Tournadre A, Lenief V, Cazalis MA, Miossec P
cocaine related behavior 12 (Cocrb12) spans 85.558736 - 135.558736 Mbp (NCBI Build 37) on Chr 11. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
QTL for alcohol preference locus on Chr11 at D11Mit35 (80.34 Mbp , Build 37)
Description:
alcohol preference locus spans 55.34 - 105.34 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for nicotine sensitivity on Chr11 at D11Mit39 (81.17 Mbp , Build 37)
Description:
nicotine sensitivity spans 56.17 - 106.17 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol preference locus on Chr11 at D11Mit35 (106.61 Mbp , Build 37)
Description:
alcohol preference locus spans 81.61 - 131.61 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'Interleukin 1 Receptor Antagonist Protein' (D053590). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Azaguanine' (D001375). Incorporates data from 134 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '5-dihydrocortisone' (C045993). Incorporates data from 1538 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'Ionomycin' (D015759). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Mytilus galloprovincialis that interact with the MeSH term 'titanium dioxide' (C009495). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Dexamethasone' (D003907). Incorporates data from 14 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Asbestos' (D001194). Incorporates data from 382 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Cyclic AMP' (D000242). Incorporates data from 39 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Theophylline' (D013806). Incorporates data from 15 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'resveratrol' (C059514). Incorporates data from 16 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
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