The total transcriptome including genes that are differentially expressed in cocaine addicts compared to control subjects. Post-mortem brain samples were collected from the dorsolateral prefrontal cortex (dlPFC) of the cocaine addict group and the control group. To assess gene expression, RNA-seq was performed. Data taken from Supplementary Table 2. Values presented are k.diff values. Data available from GEO with accession number GSE99349."
Authors:
Efrain A Ribeiro, Joseph R Scarpa, Susanna P Garamszegi, Andrew Kasarskis, Deborah C Mash, Eric J Nestler
Data from GEO GSE194368 and analyzed using GEO2R, only top gene shown. Authors identified transcriptional adaptations of GR signaling in the amygdala of humans with OUD. Thus, GRs, their coregulators and downstream systems may represent viable therapeutic targets to treat the “stress side” of OUD.
Authors:
Stephanie A Carmack, Janaina C M Vendruscolo, M Adrienne McGinn, Jorge Miranda-Barrientos, Vez Repunte-Canonigo, Gabriel D Bosse, Daniele Mercatelli, Federico M Giorgi, Yu Fu, Anthony J Hinrich, Francine M Jodelka, Karen Ling, Robert O Messing, Randall T Peterson, Frank Rigo, Scott Edwards, Pietro P Sanna, Marisela Morales, Michelle L Hastings, George F Koob, Leandro F Vendruscolo
QTL for METH responses for body temperature on Chr1 at D1Ncvs75 (79.87 Mbp , Build 37)
Description:
METH responses for body temperature spans 54.87 - 104.87 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for chronic alcohol withdrawal severity on Chr1 at D1Mit46 (83.89 Mbp , Build 37)
Description:
chronic alcohol withdrawal severity spans 58.89 - 108.89 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Bergeson SE, Kyle Warren R, Crabbe JC, Metten P, Gene Erwin V, Belknap JK
Genes associated with Homo sapiens that interact with the MeSH term 'Aflatoxin B1' (D016604). Incorporates data from 5 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Plant Extracts' (D010936). Incorporates data from 489 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
QTL associated with B.burgdorferi-associated arthritis 11. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (65896421)
Authors:
Roper RJ, Weis JJ, McCracken BA, Green CB, Ma Y, Weber KS, Fairbairn D, Butterfield RJ, Potter MR, Zachary JF, Doerge RW, Teuscher C
QTL associated with bone response to mechanical loading 8. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (78202934)
QTL associated with cyclophosphamide induced apoptosis. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (66992757)
Authors:
Bergman ML, Cilio CM, Penha-Gonalves C, Lamhamedi-Cherradi SE, Lfgren A, Colucci F, Lejon K, Garchon HJ, Holmberg D
QTL associated with cytokine deficiency colitis susceptibility 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (65899760)
QTL associated with cocaine induced activation 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (88315827)
QTL associated with dependence on morphine QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (90464815)
QTL associated with darker modification of yellow agouti QTL 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (73734337)
QTL associated with "early growth rate, maternal effect 1". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (74999392)
QTL associated with granulosa cell tumorigenesis 7. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (64357309)
Authors:
Dorward AM, Shultz KL, Horton LG, Li R, Churchill GA, Beamer WG
QTL associated with horizontal distance traveled. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (90464815)
QTL associated with heart rate quantitative locus 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (92584545)
Authors:
Sugiyama F, Churchill GA, Li R, Libby LJ, Carver T, Yagami K, John SW, Paigen B
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