List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Liver enzyme levels (gamma-glutamyl transferase). The EFO term serum gamma-glutamyl transferase measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JC Chambers, W Zhang, J Sehmi, X Li, MN Wass, P Van der Harst, H Holm, S Sanna, M Kavousi, SE Baumeister, LJ Coin, G Deng, C Gieger, NL Heard-Costa, JJ Hottenga, B Kühnel, V Kumar, V Lagou, L Liang, J Luan, PM Vidal, I Mateo Leach, PF O'Reilly, JF Peden, N Rahmioglu, P Soininen, EK Speliotes, X Yuan, G Thorleifsson, BZ Alizadeh, LD Atwood, IB Borecki, MJ Brown, P Charoen, F Cucca, D Das, EJ de Geus, AL Dixon, A Döring, G Ehret, GI Eyjolfsson, M Farrall, NG Forouhi, N Friedrich, W Goessling, DF Gudbjartsson, TB Harris, AL Hartikainen, S Heath, GM Hirschfield, A Hofman, G Homuth, E Hyppönen, HL Janssen, T Johnson, AJ Kangas, IP Kema, JP Kühn, S Lai, M Lathrop, MM Lerch, Y Li, TJ Liang, JP Lin, RJ Loos, NG Martin, MF Moffatt, GW Montgomery, PB Munroe, K Musunuru, Y Nakamura, CJ O'Donnell, I Olafsson, BW Penninx, A Pouta, BP Prins, I Prokopenko, R Puls, A Ruokonen, MJ Savolainen, D Schlessinger, JN Schouten, U Seedorf, S Sen-Chowdhry, KA Siminovitch, JH Smit, TD Spector, W Tan, TM Teslovich, T Tukiainen, AG Uitterlinden, MM Van der Klauw, RS Vasan, C Wallace, H Wallaschofski, HE Wichmann, G Willemsen, P Würtz, C Xu, LM Yerges-Armstrong, GR Abecasis, KR Ahmadi, DI Boomsma, M Caulfield, WO Cookson, CM van Duijn, P Froguel, K Matsuda, MI McCarthy, C Meisinger, V Mooser, KH Pietiläinen, G Schumann, H Snieder, MJ Sternberg, RP Stolk, HC Thomas, U Thorsteinsdottir, M Uda, G Waeber, NJ Wareham, DM Waterworth, H Watkins, JB Whitfield, JC Witteman, BH Wolffenbuttel, CS Fox, M Ala-Korpela, K Stefansson, P Vollenweider, H Völzke, EE Schadt, J Scott, MR Järvelin, P Elliott, JS Kooner
Whole Brain Gene Expression Correlates for NEPDIST30 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The NEPDIST30 measures Novel environment distance (cm) travelled min 15-30 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Neocortex Gene Expression Correlates for SPD_TIMEDOWEL30SEC measured in BXD RI Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The SPD_TIMEDOWEL30SEC measures Dowel Test - Time 30 Sec under the domain Porsolt. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for high-dose ethanol actions on Chr18 at D18Mit7 (73.95 Mbp , Build 37)
Description:
high-dose ethanol actions spans 48.95 - 98.95 Mbp (NCBI Build 37) on Chr18. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Erwin VG, Markel PD, Johnson TE, Gehle VM, Jones BC
Genes associated with Homo sapiens that interact with the MeSH term 'entinostat' (C118739). Incorporates data from 11 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'Ionomycin' (D015759). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Coumestrol' (D003375). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine' (C516138). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Vitamin E' (D014810). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Zidovudine' (D015215). Incorporates data from 16 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'vorinostat' (C111237). Incorporates data from 13 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Tretinoin' (D014212). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'cobaltous chloride' (C018021). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Rodentia that interact with the MeSH term 'Drugs, Chinese Herbal' (D004365). Incorporates data from 10 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryzias latipes that interact with the MeSH term 'Estradiol' (D004958). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide' (D015123). Incorporates data from 660 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'p-Chloromercuribenzoic Acid' (D020245). Incorporates data from 96 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'testosterone enanthate' (C004648). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Ovis aries that interact with the MeSH term 'Progesterone' (D011374). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Cyclosporine' (D016572). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'panobinostat' (C496932). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Aflatoxin B1' (D016604). Incorporates data from 5 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '1-nitropyrene' (C032668). Incorporates data from 12 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Plant Extracts' (D010936). Incorporates data from 489 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
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