List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor. The EFO term AR-C124910XX measurement, acute coronary syndrome was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
C Varenhorst, N Eriksson, Å Johansson, BJ Barratt, E Hagström, A Åkerblom, AC Syvänen, RC Becker, SK James, HA Katus, S Husted, PG Steg, A Siegbahn, D Voora, R Teng, RF Storey, L Wallentin
This gene set described genes that are up-regulated by the androgen receptor (AR). The set was derived by finding the intersection of a set of genes close to AR binding sites and a set of genes that were reported as AR-dependent. The set was further refined by microarray analysis of control and cells treated with synthetic androgen. The data is reported in supplementary file 1B and the HGNC gene symbols were used. The genes represent genes that were up-regulated at least 2-fold and the values represent the reported p-values.
Authors:
Liu S, Kumari S, Hu Q, Senapati D, Venkadakrishnan VB, Wang D, DePriest AD, Schlanger SE, Ben-Salem S, Valenzuela MM, Willard B, Mudambi S, Swetzig WM, Das GM, Shourideh M, Koochekpour S, Falzarano SM, Magi-Galluzzi C, Yadav N, Chen X, Lao C, Wang J, Billaud JN, Heemers HV
This gene set described genes that are down-regulated by the androgen receptor (AR). The set was derived by finding the intersection of a set of genes close to AR binding sites and a set of genes that were reported as AR-dependent. The set was further refined by microarray analysis of control and cells treated with synthetic androgen. The data is reported in supplementary file 1B and the HGNC gene symbols were used. The genes represent genes that were down-regulated at least 2-fold and the values represent the reported p-values.
Authors:
Liu S, Kumari S, Hu Q, Senapati D, Venkadakrishnan VB, Wang D, DePriest AD, Schlanger SE, Ben-Salem S, Valenzuela MM, Willard B, Mudambi S, Swetzig WM, Das GM, Shourideh M, Koochekpour S, Falzarano SM, Magi-Galluzzi C, Yadav N, Chen X, Lao C, Wang J, Billaud JN, Heemers HV
This gene set is from supplemental figure 1 and describes genes that are classified as co-regulators acting with the androgen receptor (AR). This set was manually curated from the literature by the authors.
Authors:
Liu S, Kumari S, Hu Q, Senapati D, Venkadakrishnan VB, Wang D, DePriest AD, Schlanger SE, Ben-Salem S, Valenzuela MM, Willard B, Mudambi S, Swetzig WM, Das GM, Shourideh M, Koochekpour S, Falzarano SM, Magi-Galluzzi C, Yadav N, Chen X, Lao C, Wang J, Billaud JN, Heemers HV
Genes associated with nan that interact with the MeSH term 'AR-R 17779' (C408128). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'ar-turmerone' (C078098). Incorporates data from 21 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Online Mendelian Inheritance in Man (OMIM) Geneset. This geneset contains genes that have been mapped to the following disorder: Familial Mediterranean fever, AR. This data was retrieved and parsed from the Morbid Map dataset provided by OMIM.
gene2omim v. 0.1.0
Last updated 2015.08.31
Genes associated with nan that interact with the MeSH term 'AR-C239' (C032994). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Rattus norvegicus that interact with the MeSH term 'AR-R 17779' (C408128). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
androgen receptor coregulators misregulated in PCa
Description:
This gene set is from supplemental figure 1 and describes genes that are classified as co-regulators acting with the androgen receptor (AR) and further classified as having differences in protein expression between prostate cancer and benign prostate. This set was manually curated by the authors.
Authors:
Liu S, Kumari S, Hu Q, Senapati D, Venkadakrishnan VB, Wang D, DePriest AD, Schlanger SE, Ben-Salem S, Valenzuela MM, Willard B, Mudambi S, Swetzig WM, Das GM, Shourideh M, Koochekpour S, Falzarano SM, Magi-Galluzzi C, Yadav N, Chen X, Lao C, Wang J, Billaud JN, Heemers HV
This set is from supplemental figure 1 and represents androgen receptor co-regulators that were differentially expressed in aggressive prostate cancer.
Authors:
Liu S, Kumari S, Hu Q, Senapati D, Venkadakrishnan VB, Wang D, DePriest AD, Schlanger SE, Ben-Salem S, Valenzuela MM, Willard B, Mudambi S, Swetzig WM, Das GM, Shourideh M, Koochekpour S, Falzarano SM, Magi-Galluzzi C, Yadav N, Chen X, Lao C, Wang J, Billaud JN, Heemers HV
GWAS: low density lipoprotein cholesterol measurement
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was LDL cholesterol. The EFO term low density lipoprotein cholesterol measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
C Sabatti, SK Service, AL Hartikainen, A Pouta, S Ripatti, J Brodsky, CG Jones, NA Zaitlen, T Varilo, M Kaakinen, U Sovio, A Ruokonen, J Laitinen, E Jakkula, L Coin, C Hoggart, A Collins, H Turunen, S Gabriel, P Elliot, MI McCarthy, MJ Daly, MR Järvelin, NB Freimer, L Peltonen
Genes were identified by expression clustering analysis of a large number of breast cancer samples. Direction of regulation was curated from supplemental table S3B. Values represent Bonferroni corrected p-values of T-tests shown in supplemental table S3C. p-value scores were selected to be <0.05. HGNC identifiers were mapped to gene symbols manually. Symbols were associated with HGNC identifiers that mapped to approved symbols if they mapped to more than one HGNC identifier. Symbols which were not confidently mapped were not included.
Authors:
Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y, Pietenpol JA
Genes were identified by expression clustering analysis of a large number of breast cancer samples. Direction of regulation was curated from supplemental table S3B. Values represent Bonferroni corrected p-values of T-tests shown in supplemental table S3C. p-value scores were selected to be <0.05. HGNC identifiers were mapped to gene symbols manually. Symbols were associated with HGNC identifiers that mapped to approved symbols if they mapped to more than one HGNC identifier. Symbols which were not confidently mapped were not included.
Authors:
Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y, Pietenpol JA
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Male-pattern baldness. The EFO term androgenetic alopecia was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
FF Brockschmidt, S Heilmann, JA Ellis, S Eigelshoven, S Hanneken, C Herold, S Moebus, MA Alblas, B Lippke, N Kluck, L Priebe, FA Degenhardt, RA Jamra, C Meesters, KH Jöckel, R Erbel, S Harrap, J Schumacher, H Fröhlich, R Kruse, AM Hillmer, T Becker, MM Nöthen
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Male-pattern baldness. The EFO term androgenetic alopecia was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JB Richards, X Yuan, F Geller, D Waterworth, V Bataille, D Glass, K Song, G Waeber, P Vollenweider, KK Aben, LA Kiemeney, B Walters, N Soranzo, U Thorsteinsdottir, A Kong, T Rafnar, P Deloukas, P Sulem, H Stefansson, K Stefansson, TD Spector, V Mooser
Genes downregulated by at least two-fold in the BLIA subtype of breast cancer. The data is from supplemental table S37 and the values reported are the fold changes calculated from the log values reported for the Discovery Set. HGNC identifiers were mapped to gene symbols manually. Symbols were associated with HGNC identifiers that mapped to approved symbols if they mapped to more than one HGNC identifier. Symbols which were not confidently mapped were not included.
Authors:
Burstein MD, Tsimelzon A, Poage GM, Covington KR, Contreras A, Fuqua SA, Savage MI, Osborne CK, Hilsenbeck SG, Chang JC, Mills GB, Lau CC, Brown PH
Genes upregulated by at least two-fold in the LAR subtype of triple negative breast cancer. The data is from supplemental table S37 and the values reported are the fold changes calculated from the log values reported for the Discovery Set. HGNC identifiers were mapped to gene symbols manually. Symbols were associated with HGNC identifiers that mapped to approved symbols if they mapped to more than one HGNC identifier. Symbols which were not confidently mapped were not included.
Authors:
Burstein MD, Tsimelzon A, Poage GM, Covington KR, Contreras A, Fuqua SA, Savage MI, Osborne CK, Hilsenbeck SG, Chang JC, Mills GB, Lau CC, Brown PH
Genes that are up-regulated after LAPC4 prostate cancer cells over-expressing the androgen receptor and treated with bicalutamide. The authors demonstrate that this leads to expression of AR-responsinve genes. The genes are from Supplemental figure 2 and represent genes upregulated2-fold with a p <0.05. The table was manually converted to HGNC identifiers by manual inspection to standardize gene representation. When several identifiers in supplemental figure 2 mapped to a single HGNC identifier, the identifier was only entered once.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Body mass index. The EFO term body mass index was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, H Lango Allen, CM Lindgren, J Luan, R Mägi, JC Randall, S Vedantam, TW Winkler, L Qi, T Workalemahu, IM Heid, V Steinthorsdottir, HM Stringham, MN Weedon, E Wheeler, AR Wood, T Ferreira, RJ Weyant, AV Segrè, K Estrada, L Liang, J Nemesh, JH Park, S Gustafsson, TO Kilpeläinen, J Yang, N Bouatia-Naji, T Esko, MF Feitosa, Z Kutalik, M Mangino, S Raychaudhuri, A Scherag, AV Smith, R Welch, JH Zhao, KK Aben, DM Absher, N Amin, AL Dixon, E Fisher, NL Glazer, ME Goddard, NL Heard-Costa, V Hoesel, JJ Hottenga, A Johansson, T Johnson, S Ketkar, C Lamina, S Li, MF Moffatt, RH Myers, N Narisu, JR Perry, MJ Peters, M Preuss, S Ripatti, F Rivadeneira, C Sandholt, LJ Scott, NJ Timpson, JP Tyrer, S van Wingerden, RM Watanabe, CC White, F Wiklund, C Barlassina, DI Chasman, MN Cooper, JO Jansson, RW Lawrence, N Pellikka, I Prokopenko, J Shi, E Thiering, H Alavere, MT Alibrandi, P Almgren, AM Arnold, T Aspelund, LD Atwood, B Balkau, AJ Balmforth, AJ Bennett, Y Ben-Shlomo, RN Bergman, S Bergmann, H Biebermann, AI Blakemore, T Boes, LL Bonnycastle, SR Bornstein, MJ Brown, TA Buchanan, F Busonero, H Campbell, FP Cappuccio, C Cavalcanti-Proença, YD Chen, CM Chen, PS Chines, R Clarke, L Coin, J Connell, IN Day, M den Heijer, J Duan, S Ebrahim, P Elliott, R Elosua, G Eiriksdottir, MR Erdos, JG Eriksson, MF Facheris, SB Felix, P Fischer-Posovszky, AR Folsom, N Friedrich, NB Freimer, M Fu, S Gaget, PV Gejman, EJ Geus, C Gieger, AP Gjesing, A Goel, P Goyette, H Grallert, J Grässler, DM Greenawalt, CJ Groves, V Gudnason, C Guiducci, AL Hartikainen, N Hassanali, AS Hall, AS Havulinna, C Hayward, AC Heath, C Hengstenberg, AA Hicks, A Hinney, A Hofman, G Homuth, J Hui, W Igl, C Iribarren, B Isomaa, KB Jacobs, I Jarick, E Jewell, U John, T Jørgensen, P Jousilahti, A Jula, M Kaakinen, E Kajantie, LM Kaplan, S Kathiresan, J Kettunen, L Kinnunen, JW Knowles, I Kolcic, IR König, S Koskinen, P Kovacs, J Kuusisto, P Kraft, K Kvaløy, J Laitinen, O Lantieri, C Lanzani, LJ Launer, C Lecoeur, T Lehtimäki, G Lettre, J Liu, ML Lokki, M Lorentzon, RN Luben, B Ludwig, P Manunta, D Marek, M Marre, NG Martin, WL McArdle, A McCarthy, B McKnight, T Meitinger, O Melander, D Meyre, K Midthjell, GW Montgomery, MA Morken, AP Morris, R Mulic, JS Ngwa, M Nelis, MJ Neville, DR Nyholt, CJ O'Donnell, S O'Rahilly, KK Ong, B Oostra, G Paré, AN Parker, M Perola, I Pichler, KH Pietiläinen, CG Platou, O Polasek, A Pouta, S Rafelt, O Raitakari, NW Rayner, M Ridderstråle, W Rief, A Ruokonen, NR Robertson, P Rzehak, V Salomaa, AR Sanders, MS Sandhu, S Sanna, J Saramies, MJ Savolainen, S Scherag, S Schipf, S Schreiber, H Schunkert, K Silander, J Sinisalo, DS Siscovick, JH Smit, N Soranzo, U Sovio, J Stephens, I Surakka, AJ Swift, ML Tammesoo, JC Tardif, M Teder-Laving, TM Teslovich, JR Thompson, B Thomson, A Tönjes, T Tuomi, JB van Meurs, GJ van Ommen, V Vatin, J Viikari, S Visvikis-Siest, V Vitart, CI Vogel, BF Voight, LL Waite, H Wallaschofski, GB Walters, E Widen, S Wiegand, SH Wild, G Willemsen, DR Witte, JC Witteman, J Xu, Q Zhang, L Zgaga, A Ziegler, P Zitting, JP Beilby, IS Farooqi, J Hebebrand, HV Huikuri, AL James, M Kähönen, DF Levinson, F Macciardi, MS Nieminen, C Ohlsson, LJ Palmer, PM Ridker, M Stumvoll, JS Beckmann, H Boeing, E Boerwinkle, DI Boomsma, MJ Caulfield, SJ Chanock, FS Collins, LA Cupples, GD Smith, J Erdmann, P Froguel, H Grönberg, U Gyllensten, P Hall, T Hansen, TB Harris, AT Hattersley, RB Hayes, J Heinrich, FB Hu, K Hveem, T Illig, MR Jarvelin, J Kaprio, F Karpe, KT Khaw, LA Kiemeney, H Krude, M Laakso, DA Lawlor, A Metspalu, PB Munroe, WH Ouwehand, O Pedersen, BW Penninx, A Peters, PP Pramstaller, T Quertermous, T Reinehr, A Rissanen, I Rudan, NJ Samani, PE Schwarz, AR Shuldiner, TD Spector, J Tuomilehto, M Uda, A Uitterlinden, TT Valle, M Wabitsch, G Waeber, NJ Wareham, H Watkins, JF Wilson, AF Wright, MC Zillikens, N Chatterjee, SA McCarroll, S Purcell, EE Schadt, PM Visscher, TL Assimes, IB Borecki, P Deloukas, CS Fox, LC Groop, T Haritunians, DJ Hunter, RC Kaplan, KL Mohlke, JR O'Connell, L Peltonen, D Schlessinger, DP Strachan, CM van Duijn, HE Wichmann, TM Frayling, U Thorsteinsdottir, GR Abecasis, I Barroso, M Boehnke, K Stefansson, KE North, MI McCarthy, JN Hirschhorn, E Ingelsson, RJ Loos
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Menarche (age at onset). The EFO term age at menarche was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
CE Elks, JR Perry, P Sulem, DI Chasman, N Franceschini, C He, KL Lunetta, JA Visser, EM Byrne, DL Cousminer, DF Gudbjartsson, T Esko, B Feenstra, JJ Hottenga, DL Koller, Z Kutalik, P Lin, M Mangino, M Marongiu, PF McArdle, AV Smith, L Stolk, SH van Wingerden, JH Zhao, E Albrecht, T Corre, E Ingelsson, C Hayward, PK Magnusson, EN Smith, S Ulivi, NM Warrington, L Zgaga, H Alavere, N Amin, T Aspelund, S Bandinelli, I Barroso, GS Berenson, S Bergmann, H Blackburn, E Boerwinkle, JE Buring, F Busonero, H Campbell, SJ Chanock, W Chen, MC Cornelis, D Couper, AD Coviello, P d'Adamo, U de Faire, EJ de Geus, P Deloukas, A Döring, GD Smith, DF Easton, G Eiriksdottir, V Emilsson, J Eriksson, L Ferrucci, AR Folsom, T Foroud, M Garcia, P Gasparini, F Geller, C Gieger, V Gudnason, P Hall, SE Hankinson, L Ferreli, AC Heath, DG Hernandez, A Hofman, FB Hu, T Illig, MR Järvelin, AD Johnson, D Karasik, KT Khaw, DP Kiel, TO Kilpeläinen, I Kolcic, P Kraft, LJ Launer, JS Laven, S Li, J Liu, D Levy, NG Martin, WL McArdle, M Melbye, V Mooser, JC Murray, SS Murray, MA Nalls, P Navarro, M Nelis, AR Ness, K Northstone, BA Oostra, M Peacock, LJ Palmer, A Palotie, G Paré, AN Parker, NL Pedersen, L Peltonen, CE Pennell, P Pharoah, O Polasek, AS Plump, A Pouta, E Porcu, T Rafnar, JP Rice, SM Ring, F Rivadeneira, I Rudan, C Sala, V Salomaa, S Sanna, D Schlessinger, NJ Schork, A Scuteri, AV Segrè, AR Shuldiner, N Soranzo, U Sovio, SR Srinivasan, DP Strachan, ML Tammesoo, E Tikkanen, D Toniolo, K Tsui, L Tryggvadottir, J Tyrer, M Uda, RM van Dam, JB van Meurs, P Vollenweider, G Waeber, NJ Wareham, DM Waterworth, MN Weedon, HE Wichmann, G Willemsen, JF Wilson, AF Wright, L Young, G Zhai, WV Zhuang, LJ Bierut, DI Boomsma, HA Boyd, L Crisponi, EW Demerath, CM van Duijn, MJ Econs, TB Harris, DJ Hunter, RJ Loos, A Metspalu, GW Montgomery, PM Ridker, TD Spector, EA Streeten, K Stefansson, U Thorsteinsdottir, AG Uitterlinden, E Widen, JM Murabito, KK Ong, A Murray
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Thyroid hormone levels. The EFO term thyroid stimulating hormone measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
E Porcu, M Medici, G Pistis, CB Volpato, SG Wilson, AR Cappola, SD Bos, J Deelen, M den Heijer, RM Freathy, J Lahti, C Liu, LM Lopez, IM Nolte, JR O'Connell, T Tanaka, S Trompet, A Arnold, S Bandinelli, M Beekman, S Böhringer, SJ Brown, BM Buckley, C Camaschella, AJ de Craen, G Davies, MC de Visser, I Ford, T Forsen, TM Frayling, L Fugazzola, M Gögele, AT Hattersley, AR Hermus, A Hofman, JJ Houwing-Duistermaat, RA Jensen, E Kajantie, M Kloppenburg, EM Lim, C Masciullo, S Mariotti, C Minelli, BD Mitchell, R Nagaraja, RT Netea-Maier, A Palotie, L Persani, MG Piras, BM Psaty, K Räikkönen, JB Richards, F Rivadeneira, C Sala, MM Sabra, N Sattar, BM Shields, N Soranzo, JM Starr, DJ Stott, FC Sweep, G Usala, MM van der Klauw, D van Heemst, A van Mullem, SH Vermeulen, WE Visser, JP Walsh, RG Westendorp, E Widen, G Zhai, F Cucca, IJ Deary, JG Eriksson, L Ferrucci, CS Fox, JW Jukema, LA Kiemeney, PP Pramstaller, D Schlessinger, AR Shuldiner, EP Slagboom, AG Uitterlinden, B Vaidya, TJ Visser, BH Wolffenbuttel, I Meulenbelt, JI Rotter, TD Spector, AA Hicks, D Toniolo, S Sanna, RP Peeters, S Naitza
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Thyroid hormone levels. The EFO term thyroxine measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
E Porcu, M Medici, G Pistis, CB Volpato, SG Wilson, AR Cappola, SD Bos, J Deelen, M den Heijer, RM Freathy, J Lahti, C Liu, LM Lopez, IM Nolte, JR O'Connell, T Tanaka, S Trompet, A Arnold, S Bandinelli, M Beekman, S Böhringer, SJ Brown, BM Buckley, C Camaschella, AJ de Craen, G Davies, MC de Visser, I Ford, T Forsen, TM Frayling, L Fugazzola, M Gögele, AT Hattersley, AR Hermus, A Hofman, JJ Houwing-Duistermaat, RA Jensen, E Kajantie, M Kloppenburg, EM Lim, C Masciullo, S Mariotti, C Minelli, BD Mitchell, R Nagaraja, RT Netea-Maier, A Palotie, L Persani, MG Piras, BM Psaty, K Räikkönen, JB Richards, F Rivadeneira, C Sala, MM Sabra, N Sattar, BM Shields, N Soranzo, JM Starr, DJ Stott, FC Sweep, G Usala, MM van der Klauw, D van Heemst, A van Mullem, SH Vermeulen, WE Visser, JP Walsh, RG Westendorp, E Widen, G Zhai, F Cucca, IJ Deary, JG Eriksson, L Ferrucci, CS Fox, JW Jukema, LA Kiemeney, PP Pramstaller, D Schlessinger, AR Shuldiner, EP Slagboom, AG Uitterlinden, B Vaidya, TJ Visser, BH Wolffenbuttel, I Meulenbelt, JI Rotter, TD Spector, AA Hicks, D Toniolo, S Sanna, RP Peeters, S Naitza
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Height. The EFO term body height was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
H Lango Allen, K Estrada, G Lettre, SI Berndt, MN Weedon, F Rivadeneira, CJ Willer, AU Jackson, S Vedantam, S Raychaudhuri, T Ferreira, AR Wood, RJ Weyant, AV Segrè, EK Speliotes, E Wheeler, N Soranzo, JH Park, J Yang, D Gudbjartsson, NL Heard-Costa, JC Randall, L Qi, A Vernon Smith, R Mägi, T Pastinen, L Liang, IM Heid, J Luan, G Thorleifsson, TW Winkler, ME Goddard, K Sin Lo, C Palmer, T Workalemahu, YS Aulchenko, A Johansson, MC Zillikens, MF Feitosa, T Esko, T Johnson, S Ketkar, P Kraft, M Mangino, I Prokopenko, D Absher, E Albrecht, F Ernst, NL Glazer, C Hayward, JJ Hottenga, KB Jacobs, JW Knowles, Z Kutalik, KL Monda, O Polasek, M Preuss, NW Rayner, NR Robertson, V Steinthorsdottir, JP Tyrer, BF Voight, F Wiklund, J Xu, JH Zhao, DR Nyholt, N Pellikka, M Perola, JR Perry, I Surakka, ML Tammesoo, EL Altmaier, N Amin, T Aspelund, T Bhangale, G Boucher, DI Chasman, C Chen, L Coin, MN Cooper, AL Dixon, Q Gibson, E Grundberg, K Hao, M Juhani Junttila, LM Kaplan, J Kettunen, IR König, T Kwan, RW Lawrence, DF Levinson, M Lorentzon, B McKnight, AP Morris, M Müller, J Suh Ngwa, S Purcell, S Rafelt, RM Salem, E Salvi, S Sanna, J Shi, U Sovio, JR Thompson, MC Turchin, L Vandenput, DJ Verlaan, V Vitart, CC White, A Ziegler, P Almgren, AJ Balmforth, H Campbell, L Citterio, A De Grandi, A Dominiczak, J Duan, P Elliott, R Elosua, JG Eriksson, NB Freimer, EJ Geus, N Glorioso, S Haiqing, AL Hartikainen, AS Havulinna, AA Hicks, J Hui, W Igl, T Illig, A Jula, E Kajantie, TO Kilpeläinen, M Koiranen, I Kolcic, S Koskinen, P Kovacs, J Laitinen, J Liu, ML Lokki, A Marusic, A Maschio, T Meitinger, A Mulas, G Paré, AN Parker, JF Peden, A Petersmann, I Pichler, KH Pietiläinen, A Pouta, M Ridderstråle, JI Rotter, JG Sambrook, AR Sanders, CO Schmidt, J Sinisalo, JH Smit, HM Stringham, G Bragi Walters, E Widen, SH Wild, G Willemsen, L Zagato, L Zgaga, P Zitting, H Alavere, M Farrall, WL McArdle, M Nelis, MJ Peters, S Ripatti, JB van Meurs, KK Aben, KG Ardlie, JS Beckmann, JP Beilby, RN Bergman, S Bergmann, FS Collins, D Cusi, M den Heijer, G Eiriksdottir, PV Gejman, AS Hall, A Hamsten, HV Huikuri, C Iribarren, M Kähönen, J Kaprio, S Kathiresan, L Kiemeney, T Kocher, LJ Launer, T Lehtimäki, O Melander, TH Mosley, AW Musk, MS Nieminen, CJ O'Donnell, C Ohlsson, B Oostra, LJ Palmer, O Raitakari, PM Ridker, JD Rioux, A Rissanen, C Rivolta, H Schunkert, AR Shuldiner, DS Siscovick, M Stumvoll, A Tönjes, J Tuomilehto, GJ van Ommen, J Viikari, AC Heath, NG Martin, GW Montgomery, MA Province, M Kayser, AM Arnold, LD Atwood, E Boerwinkle, SJ Chanock, P Deloukas, C Gieger, H Grönberg, P Hall, AT Hattersley, C Hengstenberg, W Hoffman, GM Lathrop, V Salomaa, S Schreiber, M Uda, D Waterworth, AF Wright, TL Assimes, I Barroso, A Hofman, KL Mohlke, DI Boomsma, MJ Caulfield, LA Cupples, J Erdmann, CS Fox, V Gudnason, U Gyllensten, TB Harris, RB Hayes, MR Jarvelin, V Mooser, PB Munroe, WH Ouwehand, BW Penninx, PP Pramstaller, T Quertermous, I Rudan, NJ Samani, TD Spector, H Völzke, H Watkins, JF Wilson, LC Groop, T Haritunians, FB Hu, RC Kaplan, A Metspalu, KE North, D Schlessinger, NJ Wareham, DJ Hunter, JR O'Connell, DP Strachan, HE Wichmann, IB Borecki, CM van Duijn, EE Schadt, U Thorsteinsdottir, L Peltonen, AG Uitterlinden, PM Visscher, N Chatterjee, RJ Loos, M Boehnke, MI McCarthy, E Ingelsson, CM Lindgren, GR Abecasis, K Stefansson, TM Frayling, JN Hirschhorn
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Mahajan, MJ Go, W Zhang, JE Below, KJ Gaulton, T Ferreira, M Horikoshi, AD Johnson, MC Ng, I Prokopenko, D Saleheen, X Wang, E Zeggini, GR Abecasis, LS Adair, P Almgren, M Atalay, T Aung, D Baldassarre, B Balkau, Y Bao, AH Barnett, I Barroso, A Basit, LF Been, J Beilby, GI Bell, R Benediktsson, RN Bergman, BO Boehm, E Boerwinkle, LL Bonnycastle, N Burtt, Q Cai, H Campbell, J Carey, S Cauchi, M Caulfield, JC Chan, LC Chang, TJ Chang, YC Chang, G Charpentier, CH Chen, H Chen, YT Chen, KS Chia, M Chidambaram, PS Chines, NH Cho, YM Cho, LM Chuang, FS Collins, MC Cornelis, DJ Couper, AT Crenshaw, RM van Dam, J Danesh, D Das, U de Faire, G Dedoussis, P Deloukas, AS Dimas, C Dina, AS Doney, PJ Donnelly, M Dorkhan, C van Duijn, J Dupuis, S Edkins, P Elliott, V Emilsson, R Erbel, JG Eriksson, J Escobedo, T Esko, E Eury, JC Florez, P Fontanillas, NG Forouhi, T Forsen, C Fox, RM Fraser, TM Frayling, P Froguel, P Frossard, Y Gao, K Gertow, C Gieger, B Gigante, H Grallert, GB Grant, LC Grrop, CJ Groves, E Grundberg, C Guiducci, A Hamsten, BG Han, K Hara, N Hassanali, AT Hattersley, C Hayward, AK Hedman, C Herder, A Hofman, OL Holmen, K Hovingh, AB Hreidarsson, C Hu, FB Hu, J Hui, SE Humphries, SE Hunt, DJ Hunter, K Hveem, ZI Hydrie, H Ikegami, T Illig, E Ingelsson, M Islam, B Isomaa, AU Jackson, T Jafar, A James, W Jia, KH Jöckel, A Jonsson, JB Jowett, T Kadowaki, HM Kang, S Kanoni, WH Kao, S Kathiresan, N Kato, P Katulanda, KM Keinanen-Kiukaanniemi, AM Kelly, H Khan, KT Khaw, CC Khor, HL Kim, S Kim, YJ Kim, L Kinnunen, N Klopp, A Kong, E Korpi-Hyövälti, S Kowlessur, P Kraft, J Kravic, MM Kristensen, S Krithika, A Kumar, J Kumate, J Kuusisto, SH Kwak, M Laakso, V Lagou, TA Lakka, C Langenberg, C Langford, R Lawrence, K Leander, JM Lee, NR Lee, M Li, X Li, Y Li, J Liang, S Liju, WY Lim, L Lind, CM Lindgren, E Lindholm, CT Liu, JJ Liu, S Lobbens, J Long, RJ Loos, W Lu, J Luan, V Lyssenko, RC Ma, S Maeda, R Mägi, S Männisto, DR Matthews, JB Meigs, O Melander, A Metspalu, J Meyer, G Mirza, E Mihailov, S Moebus, V Mohan, KL Mohlke, AD Morris, TW Mühleisen, M Müller-Nurasyid, B Musk, J Nakamura, E Nakashima, P Navarro, PK Ng, AC Nica, PM Nilsson, I Njølstad, MM Nöthen, K Ohnaka, TH Ong, KR Owen, CN Palmer, JS Pankow, KS Park, M Parkin, S Pechlivanis, NL Pedersen, L Peltonen, JR Perry, A Peters, JM Pinidiyapathirage, CG Platou, S Potter, JF Price, L Qi, V Radha, L Rallidis, A Rasheed, W Rathman, R Rauramaa, S Raychaudhuri, NW Rayner, SD Rees, E Rehnberg, S Ripatti, N Robertson, M Roden, EJ Rossin, I Rudan, D Rybin, TE Saaristo, V Salomaa, J Saltevo, M Samuel, DK Sanghera, J Saramies, J Scott, LJ Scott, RA Scott, AV Segrè, J Sehmi, B Sennblad, N Shah, S Shah, AS Shera, XO Shu, AR Shuldiner, G Sigurđsson, E Sijbrands, A Silveira, X Sim, S Sivapalaratnam, KS Small, WY So, A Stančáková, K Stefansson, G Steinbach, V Steinthorsdottir, K Stirrups, RJ Strawbridge, HM Stringham, Q Sun, C Suo, AC Syvänen, R Takayanagi, F Takeuchi, WT Tay, TM Teslovich, B Thorand, G Thorleifsson, U Thorsteinsdottir, E Tikkanen, J Trakalo, E Tremoli, MD Trip, FJ Tsai, T Tuomi, J Tuomilehto, AG Uitterlinden, A Valladares-Salgado, S Vedantam, F Veglia, BF Voight, C Wang, NJ Wareham, R Wennauer, AR Wickremasinghe, T Wilsgaard, JF Wilson, S Wiltshire, W Winckler, TY Wong, AR Wood, JY Wu, Y Wu, K Yamamoto, T Yamauchi, M Yang, L Yengo, M Yokota, R Young, D Zabaneh, F Zhang, R Zhang, W Zheng, PZ Zimmet, D Altshuler, DW Bowden, YS Cho, NJ Cox, M Cruz, CL Hanis, J Kooner, JY Lee, M Seielstad, YY Teo, M Boehnke, EJ Parra, JC Chambers, ES Tai, MI McCarthy, AP Morris
GeneWeaver