List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Birth weight. The EFO term birth weight was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
RM Freathy, DO Mook-Kanamori, U Sovio, I Prokopenko, NJ Timpson, DJ Berry, NM Warrington, E Widen, JJ Hottenga, M Kaakinen, LA Lange, JP Bradfield, M Kerkhof, JA Marsh, R Mägi, CM Chen, HN Lyon, M Kirin, LS Adair, YS Aulchenko, AJ Bennett, JB Borja, N Bouatia-Naji, P Charoen, LJ Coin, DL Cousminer, EJ de Geus, P Deloukas, P Elliott, DM Evans, P Froguel, B Glaser, CJ Groves, AL Hartikainen, N Hassanali, JN Hirschhorn, A Hofman, JM Holly, E Hyppönen, S Kanoni, BA Knight, J Laitinen, CM Lindgren, WL McArdle, PF O'Reilly, CE Pennell, DS Postma, A Pouta, A Ramasamy, NW Rayner, SM Ring, F Rivadeneira, BM Shields, DP Strachan, I Surakka, A Taanila, C Tiesler, AG Uitterlinden, CM van Duijn, AH Wijga, G Willemsen, H Zhang, J Zhao, JF Wilson, EA Steegers, AT Hattersley, JG Eriksson, L Peltonen, KL Mohlke, SF Grant, H Hakonarson, GH Koppelman, GV Dedoussis, J Heinrich, MW Gillman, LJ Palmer, TM Frayling, DI Boomsma, G Davey Smith, C Power, VW Jaddoe, MR Jarvelin, MI McCarthy
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Two-hour glucose challenge. The EFO term glucose tolerance test was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Birth weight. The EFO term birth weight was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Fasting glucose-related traits. The EFO term fasting blood glucose measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, AU Jackson, E Wheeler, NL Glazer, N Bouatia-Naji, AL Gloyn, CM Lindgren, R Mägi, AP Morris, J Randall, T Johnson, P Elliott, D Rybin, G Thorleifsson, V Steinthorsdottir, P Henneman, H Grallert, A Dehghan, JJ Hottenga, CS Franklin, P Navarro, K Song, A Goel, JR Perry, JM Egan, T Lajunen, N Grarup, T Sparsø, A Doney, BF Voight, HM Stringham, M Li, S Kanoni, P Shrader, C Cavalcanti-Proença, M Kumari, L Qi, NJ Timpson, C Gieger, C Zabena, G Rocheleau, E Ingelsson, P An, J O'Connell, J Luan, A Elliott, SA McCarroll, F Payne, RM Roccasecca, F Pattou, P Sethupathy, K Ardlie, Y Ariyurek, B Balkau, P Barter, JP Beilby, Y Ben-Shlomo, R Benediktsson, AJ Bennett, S Bergmann, M Bochud, E Boerwinkle, A Bonnefond, LL Bonnycastle, K Borch-Johnsen, Y Böttcher, E Brunner, SJ Bumpstead, G Charpentier, YD Chen, P Chines, R Clarke, LJ Coin, MN Cooper, M Cornelis, G Crawford, L Crisponi, IN Day, EJ de Geus, J Delplanque, C Dina, MR Erdos, AC Fedson, A Fischer-Rosinsky, NG Forouhi, CS Fox, R Frants, MG Franzosi, P Galan, MO Goodarzi, J Graessler, CJ Groves, S Grundy, R Gwilliam, U Gyllensten, S Hadjadj, G Hallmans, N Hammond, X Han, AL Hartikainen, N Hassanali, C Hayward, SC Heath, S Hercberg, C Herder, AA Hicks, DR Hillman, AD Hingorani, A Hofman, J Hui, J Hung, B Isomaa, PR Johnson, T Jørgensen, A Jula, M Kaakinen, J Kaprio, YA Kesaniemi, M Kivimaki, B Knight, S Koskinen, P Kovacs, KO Kyvik, GM Lathrop, DA Lawlor, O Le Bacquer, C Lecoeur, Y Li, V Lyssenko, R Mahley, M Mangino, AK Manning, MT MartÃnez-Larrad, JB McAteer, LJ McCulloch, R McPherson, C Meisinger, D Melzer, D Meyre, BD Mitchell, MA Morken, S Mukherjee, S Naitza, N Narisu, MJ Neville, BA Oostra, M Orrù, R Pakyz, CN Palmer, G Paolisso, C Pattaro, D Pearson, JF Peden, NL Pedersen, M Perola, AF Pfeiffer, I Pichler, O Polasek, D Posthuma, SC Potter, A Pouta, MA Province, BM Psaty, W Rathmann, NW Rayner, K Rice, S Ripatti, F Rivadeneira, M Roden, O Rolandsson, A Sandbaek, M Sandhu, S Sanna, AA Sayer, P Scheet, LJ Scott, U Seedorf, SJ Sharp, B Shields, G Sigurethsson, EJ Sijbrands, A Silveira, L Simpson, A Singleton, NL Smith, U Sovio, A Swift, H Syddall, AC Syvänen, T Tanaka, B Thorand, J Tichet, A Tönjes, T Tuomi, AG Uitterlinden, KW van Dijk, M van Hoek, D Varma, S Visvikis-Siest, V Vitart, N Vogelzangs, G Waeber, PJ Wagner, A Walley, GB Walters, KL Ward, H Watkins, MN Weedon, SH Wild, G Willemsen, JC Witteman, JW Yarnell, E Zeggini, D Zelenika, B Zethelius, G Zhai, JH Zhao, MC Zillikens, IB Borecki, RJ Loos, P Meneton, PK Magnusson, DM Nathan, GH Williams, AT Hattersley, K Silander, V Salomaa, GD Smith, SR Bornstein, P Schwarz, J Spranger, F Karpe, AR Shuldiner, C Cooper, GV Dedoussis, M Serrano-RÃos, AD Morris, L Lind, LJ Palmer, FB Hu, PW Franks, S Ebrahim, M Marmot, WH Kao, JS Pankow, MJ Sampson, J Kuusisto, M Laakso, T Hansen, O Pedersen, PP Pramstaller, HE Wichmann, T Illig, I Rudan, AF Wright, M Stumvoll, H Campbell, JF Wilson, RN Bergman, TA Buchanan, FS Collins, KL Mohlke, J Tuomilehto, TT Valle, D Altshuler, JI Rotter, DS Siscovick, BW Penninx, DI Boomsma, P Deloukas, TD Spector, TM Frayling, L Ferrucci, A Kong, U Thorsteinsdottir, K Stefansson, CM van Duijn, YS Aulchenko, A Cao, A Scuteri, D Schlessinger, M Uda, A Ruokonen, MR Jarvelin, DM Waterworth, P Vollenweider, L Peltonen, V Mooser, GR Abecasis, NJ Wareham, R Sladek, P Froguel, RM Watanabe, JB Meigs, L Groop, M Boehnke, MI McCarthy, JC Florez, I Barroso
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Fasting glucose-related traits. The EFO term HOMA-B was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, AU Jackson, E Wheeler, NL Glazer, N Bouatia-Naji, AL Gloyn, CM Lindgren, R Mägi, AP Morris, J Randall, T Johnson, P Elliott, D Rybin, G Thorleifsson, V Steinthorsdottir, P Henneman, H Grallert, A Dehghan, JJ Hottenga, CS Franklin, P Navarro, K Song, A Goel, JR Perry, JM Egan, T Lajunen, N Grarup, T Sparsø, A Doney, BF Voight, HM Stringham, M Li, S Kanoni, P Shrader, C Cavalcanti-Proença, M Kumari, L Qi, NJ Timpson, C Gieger, C Zabena, G Rocheleau, E Ingelsson, P An, J O'Connell, J Luan, A Elliott, SA McCarroll, F Payne, RM Roccasecca, F Pattou, P Sethupathy, K Ardlie, Y Ariyurek, B Balkau, P Barter, JP Beilby, Y Ben-Shlomo, R Benediktsson, AJ Bennett, S Bergmann, M Bochud, E Boerwinkle, A Bonnefond, LL Bonnycastle, K Borch-Johnsen, Y Böttcher, E Brunner, SJ Bumpstead, G Charpentier, YD Chen, P Chines, R Clarke, LJ Coin, MN Cooper, M Cornelis, G Crawford, L Crisponi, IN Day, EJ de Geus, J Delplanque, C Dina, MR Erdos, AC Fedson, A Fischer-Rosinsky, NG Forouhi, CS Fox, R Frants, MG Franzosi, P Galan, MO Goodarzi, J Graessler, CJ Groves, S Grundy, R Gwilliam, U Gyllensten, S Hadjadj, G Hallmans, N Hammond, X Han, AL Hartikainen, N Hassanali, C Hayward, SC Heath, S Hercberg, C Herder, AA Hicks, DR Hillman, AD Hingorani, A Hofman, J Hui, J Hung, B Isomaa, PR Johnson, T Jørgensen, A Jula, M Kaakinen, J Kaprio, YA Kesaniemi, M Kivimaki, B Knight, S Koskinen, P Kovacs, KO Kyvik, GM Lathrop, DA Lawlor, O Le Bacquer, C Lecoeur, Y Li, V Lyssenko, R Mahley, M Mangino, AK Manning, MT MartÃnez-Larrad, JB McAteer, LJ McCulloch, R McPherson, C Meisinger, D Melzer, D Meyre, BD Mitchell, MA Morken, S Mukherjee, S Naitza, N Narisu, MJ Neville, BA Oostra, M Orrù, R Pakyz, CN Palmer, G Paolisso, C Pattaro, D Pearson, JF Peden, NL Pedersen, M Perola, AF Pfeiffer, I Pichler, O Polasek, D Posthuma, SC Potter, A Pouta, MA Province, BM Psaty, W Rathmann, NW Rayner, K Rice, S Ripatti, F Rivadeneira, M Roden, O Rolandsson, A Sandbaek, M Sandhu, S Sanna, AA Sayer, P Scheet, LJ Scott, U Seedorf, SJ Sharp, B Shields, G Sigurethsson, EJ Sijbrands, A Silveira, L Simpson, A Singleton, NL Smith, U Sovio, A Swift, H Syddall, AC Syvänen, T Tanaka, B Thorand, J Tichet, A Tönjes, T Tuomi, AG Uitterlinden, KW van Dijk, M van Hoek, D Varma, S Visvikis-Siest, V Vitart, N Vogelzangs, G Waeber, PJ Wagner, A Walley, GB Walters, KL Ward, H Watkins, MN Weedon, SH Wild, G Willemsen, JC Witteman, JW Yarnell, E Zeggini, D Zelenika, B Zethelius, G Zhai, JH Zhao, MC Zillikens, IB Borecki, RJ Loos, P Meneton, PK Magnusson, DM Nathan, GH Williams, AT Hattersley, K Silander, V Salomaa, GD Smith, SR Bornstein, P Schwarz, J Spranger, F Karpe, AR Shuldiner, C Cooper, GV Dedoussis, M Serrano-RÃos, AD Morris, L Lind, LJ Palmer, FB Hu, PW Franks, S Ebrahim, M Marmot, WH Kao, JS Pankow, MJ Sampson, J Kuusisto, M Laakso, T Hansen, O Pedersen, PP Pramstaller, HE Wichmann, T Illig, I Rudan, AF Wright, M Stumvoll, H Campbell, JF Wilson, RN Bergman, TA Buchanan, FS Collins, KL Mohlke, J Tuomilehto, TT Valle, D Altshuler, JI Rotter, DS Siscovick, BW Penninx, DI Boomsma, P Deloukas, TD Spector, TM Frayling, L Ferrucci, A Kong, U Thorsteinsdottir, K Stefansson, CM van Duijn, YS Aulchenko, A Cao, A Scuteri, D Schlessinger, M Uda, A Ruokonen, MR Jarvelin, DM Waterworth, P Vollenweider, L Peltonen, V Mooser, GR Abecasis, NJ Wareham, R Sladek, P Froguel, RM Watanabe, JB Meigs, L Groop, M Boehnke, MI McCarthy, JC Florez, I Barroso
Study analyzed 812 differentially expressed gene candidates from peripheral blood mononuclear cells (PBMC) from morphine and saline treated rats, and suggests similarities between the gene expression profile in PBMCs and in the brain of morphine-treated rats. This set contains the 79 genes implicated by this study to modulate expression during chronic morphine treatment.
Authors:
Desjardins S, Belkai E, Crete D, Cordonnier L, Scherrmann JM, Noble F, Marie-Claire C
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Fasting glucose-related traits. The EFO term HOMA-IR was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, AU Jackson, E Wheeler, NL Glazer, N Bouatia-Naji, AL Gloyn, CM Lindgren, R Mägi, AP Morris, J Randall, T Johnson, P Elliott, D Rybin, G Thorleifsson, V Steinthorsdottir, P Henneman, H Grallert, A Dehghan, JJ Hottenga, CS Franklin, P Navarro, K Song, A Goel, JR Perry, JM Egan, T Lajunen, N Grarup, T Sparsø, A Doney, BF Voight, HM Stringham, M Li, S Kanoni, P Shrader, C Cavalcanti-Proença, M Kumari, L Qi, NJ Timpson, C Gieger, C Zabena, G Rocheleau, E Ingelsson, P An, J O'Connell, J Luan, A Elliott, SA McCarroll, F Payne, RM Roccasecca, F Pattou, P Sethupathy, K Ardlie, Y Ariyurek, B Balkau, P Barter, JP Beilby, Y Ben-Shlomo, R Benediktsson, AJ Bennett, S Bergmann, M Bochud, E Boerwinkle, A Bonnefond, LL Bonnycastle, K Borch-Johnsen, Y Böttcher, E Brunner, SJ Bumpstead, G Charpentier, YD Chen, P Chines, R Clarke, LJ Coin, MN Cooper, M Cornelis, G Crawford, L Crisponi, IN Day, EJ de Geus, J Delplanque, C Dina, MR Erdos, AC Fedson, A Fischer-Rosinsky, NG Forouhi, CS Fox, R Frants, MG Franzosi, P Galan, MO Goodarzi, J Graessler, CJ Groves, S Grundy, R Gwilliam, U Gyllensten, S Hadjadj, G Hallmans, N Hammond, X Han, AL Hartikainen, N Hassanali, C Hayward, SC Heath, S Hercberg, C Herder, AA Hicks, DR Hillman, AD Hingorani, A Hofman, J Hui, J Hung, B Isomaa, PR Johnson, T Jørgensen, A Jula, M Kaakinen, J Kaprio, YA Kesaniemi, M Kivimaki, B Knight, S Koskinen, P Kovacs, KO Kyvik, GM Lathrop, DA Lawlor, O Le Bacquer, C Lecoeur, Y Li, V Lyssenko, R Mahley, M Mangino, AK Manning, MT MartÃnez-Larrad, JB McAteer, LJ McCulloch, R McPherson, C Meisinger, D Melzer, D Meyre, BD Mitchell, MA Morken, S Mukherjee, S Naitza, N Narisu, MJ Neville, BA Oostra, M Orrù, R Pakyz, CN Palmer, G Paolisso, C Pattaro, D Pearson, JF Peden, NL Pedersen, M Perola, AF Pfeiffer, I Pichler, O Polasek, D Posthuma, SC Potter, A Pouta, MA Province, BM Psaty, W Rathmann, NW Rayner, K Rice, S Ripatti, F Rivadeneira, M Roden, O Rolandsson, A Sandbaek, M Sandhu, S Sanna, AA Sayer, P Scheet, LJ Scott, U Seedorf, SJ Sharp, B Shields, G Sigurethsson, EJ Sijbrands, A Silveira, L Simpson, A Singleton, NL Smith, U Sovio, A Swift, H Syddall, AC Syvänen, T Tanaka, B Thorand, J Tichet, A Tönjes, T Tuomi, AG Uitterlinden, KW van Dijk, M van Hoek, D Varma, S Visvikis-Siest, V Vitart, N Vogelzangs, G Waeber, PJ Wagner, A Walley, GB Walters, KL Ward, H Watkins, MN Weedon, SH Wild, G Willemsen, JC Witteman, JW Yarnell, E Zeggini, D Zelenika, B Zethelius, G Zhai, JH Zhao, MC Zillikens, IB Borecki, RJ Loos, P Meneton, PK Magnusson, DM Nathan, GH Williams, AT Hattersley, K Silander, V Salomaa, GD Smith, SR Bornstein, P Schwarz, J Spranger, F Karpe, AR Shuldiner, C Cooper, GV Dedoussis, M Serrano-RÃos, AD Morris, L Lind, LJ Palmer, FB Hu, PW Franks, S Ebrahim, M Marmot, WH Kao, JS Pankow, MJ Sampson, J Kuusisto, M Laakso, T Hansen, O Pedersen, PP Pramstaller, HE Wichmann, T Illig, I Rudan, AF Wright, M Stumvoll, H Campbell, JF Wilson, RN Bergman, TA Buchanan, FS Collins, KL Mohlke, J Tuomilehto, TT Valle, D Altshuler, JI Rotter, DS Siscovick, BW Penninx, DI Boomsma, P Deloukas, TD Spector, TM Frayling, L Ferrucci, A Kong, U Thorsteinsdottir, K Stefansson, CM van Duijn, YS Aulchenko, A Cao, A Scuteri, D Schlessinger, M Uda, A Ruokonen, MR Jarvelin, DM Waterworth, P Vollenweider, L Peltonen, V Mooser, GR Abecasis, NJ Wareham, R Sladek, P Froguel, RM Watanabe, JB Meigs, L Groop, M Boehnke, MI McCarthy, JC Florez, I Barroso
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Fasting glucose-related traits. The EFO term fasting blood insulin measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, AU Jackson, E Wheeler, NL Glazer, N Bouatia-Naji, AL Gloyn, CM Lindgren, R Mägi, AP Morris, J Randall, T Johnson, P Elliott, D Rybin, G Thorleifsson, V Steinthorsdottir, P Henneman, H Grallert, A Dehghan, JJ Hottenga, CS Franklin, P Navarro, K Song, A Goel, JR Perry, JM Egan, T Lajunen, N Grarup, T Sparsø, A Doney, BF Voight, HM Stringham, M Li, S Kanoni, P Shrader, C Cavalcanti-Proença, M Kumari, L Qi, NJ Timpson, C Gieger, C Zabena, G Rocheleau, E Ingelsson, P An, J O'Connell, J Luan, A Elliott, SA McCarroll, F Payne, RM Roccasecca, F Pattou, P Sethupathy, K Ardlie, Y Ariyurek, B Balkau, P Barter, JP Beilby, Y Ben-Shlomo, R Benediktsson, AJ Bennett, S Bergmann, M Bochud, E Boerwinkle, A Bonnefond, LL Bonnycastle, K Borch-Johnsen, Y Böttcher, E Brunner, SJ Bumpstead, G Charpentier, YD Chen, P Chines, R Clarke, LJ Coin, MN Cooper, M Cornelis, G Crawford, L Crisponi, IN Day, EJ de Geus, J Delplanque, C Dina, MR Erdos, AC Fedson, A Fischer-Rosinsky, NG Forouhi, CS Fox, R Frants, MG Franzosi, P Galan, MO Goodarzi, J Graessler, CJ Groves, S Grundy, R Gwilliam, U Gyllensten, S Hadjadj, G Hallmans, N Hammond, X Han, AL Hartikainen, N Hassanali, C Hayward, SC Heath, S Hercberg, C Herder, AA Hicks, DR Hillman, AD Hingorani, A Hofman, J Hui, J Hung, B Isomaa, PR Johnson, T Jørgensen, A Jula, M Kaakinen, J Kaprio, YA Kesaniemi, M Kivimaki, B Knight, S Koskinen, P Kovacs, KO Kyvik, GM Lathrop, DA Lawlor, O Le Bacquer, C Lecoeur, Y Li, V Lyssenko, R Mahley, M Mangino, AK Manning, MT MartÃnez-Larrad, JB McAteer, LJ McCulloch, R McPherson, C Meisinger, D Melzer, D Meyre, BD Mitchell, MA Morken, S Mukherjee, S Naitza, N Narisu, MJ Neville, BA Oostra, M Orrù, R Pakyz, CN Palmer, G Paolisso, C Pattaro, D Pearson, JF Peden, NL Pedersen, M Perola, AF Pfeiffer, I Pichler, O Polasek, D Posthuma, SC Potter, A Pouta, MA Province, BM Psaty, W Rathmann, NW Rayner, K Rice, S Ripatti, F Rivadeneira, M Roden, O Rolandsson, A Sandbaek, M Sandhu, S Sanna, AA Sayer, P Scheet, LJ Scott, U Seedorf, SJ Sharp, B Shields, G Sigurethsson, EJ Sijbrands, A Silveira, L Simpson, A Singleton, NL Smith, U Sovio, A Swift, H Syddall, AC Syvänen, T Tanaka, B Thorand, J Tichet, A Tönjes, T Tuomi, AG Uitterlinden, KW van Dijk, M van Hoek, D Varma, S Visvikis-Siest, V Vitart, N Vogelzangs, G Waeber, PJ Wagner, A Walley, GB Walters, KL Ward, H Watkins, MN Weedon, SH Wild, G Willemsen, JC Witteman, JW Yarnell, E Zeggini, D Zelenika, B Zethelius, G Zhai, JH Zhao, MC Zillikens, IB Borecki, RJ Loos, P Meneton, PK Magnusson, DM Nathan, GH Williams, AT Hattersley, K Silander, V Salomaa, GD Smith, SR Bornstein, P Schwarz, J Spranger, F Karpe, AR Shuldiner, C Cooper, GV Dedoussis, M Serrano-RÃos, AD Morris, L Lind, LJ Palmer, FB Hu, PW Franks, S Ebrahim, M Marmot, WH Kao, JS Pankow, MJ Sampson, J Kuusisto, M Laakso, T Hansen, O Pedersen, PP Pramstaller, HE Wichmann, T Illig, I Rudan, AF Wright, M Stumvoll, H Campbell, JF Wilson, RN Bergman, TA Buchanan, FS Collins, KL Mohlke, J Tuomilehto, TT Valle, D Altshuler, JI Rotter, DS Siscovick, BW Penninx, DI Boomsma, P Deloukas, TD Spector, TM Frayling, L Ferrucci, A Kong, U Thorsteinsdottir, K Stefansson, CM van Duijn, YS Aulchenko, A Cao, A Scuteri, D Schlessinger, M Uda, A Ruokonen, MR Jarvelin, DM Waterworth, P Vollenweider, L Peltonen, V Mooser, GR Abecasis, NJ Wareham, R Sladek, P Froguel, RM Watanabe, JB Meigs, L Groop, M Boehnke, MI McCarthy, JC Florez, I Barroso
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Fasting insulin-related traits. The EFO term HOMA-IR, fasting blood insulin measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, AU Jackson, E Wheeler, NL Glazer, N Bouatia-Naji, AL Gloyn, CM Lindgren, R Mägi, AP Morris, J Randall, T Johnson, P Elliott, D Rybin, G Thorleifsson, V Steinthorsdottir, P Henneman, H Grallert, A Dehghan, JJ Hottenga, CS Franklin, P Navarro, K Song, A Goel, JR Perry, JM Egan, T Lajunen, N Grarup, T Sparsø, A Doney, BF Voight, HM Stringham, M Li, S Kanoni, P Shrader, C Cavalcanti-Proença, M Kumari, L Qi, NJ Timpson, C Gieger, C Zabena, G Rocheleau, E Ingelsson, P An, J O'Connell, J Luan, A Elliott, SA McCarroll, F Payne, RM Roccasecca, F Pattou, P Sethupathy, K Ardlie, Y Ariyurek, B Balkau, P Barter, JP Beilby, Y Ben-Shlomo, R Benediktsson, AJ Bennett, S Bergmann, M Bochud, E Boerwinkle, A Bonnefond, LL Bonnycastle, K Borch-Johnsen, Y Böttcher, E Brunner, SJ Bumpstead, G Charpentier, YD Chen, P Chines, R Clarke, LJ Coin, MN Cooper, M Cornelis, G Crawford, L Crisponi, IN Day, EJ de Geus, J Delplanque, C Dina, MR Erdos, AC Fedson, A Fischer-Rosinsky, NG Forouhi, CS Fox, R Frants, MG Franzosi, P Galan, MO Goodarzi, J Graessler, CJ Groves, S Grundy, R Gwilliam, U Gyllensten, S Hadjadj, G Hallmans, N Hammond, X Han, AL Hartikainen, N Hassanali, C Hayward, SC Heath, S Hercberg, C Herder, AA Hicks, DR Hillman, AD Hingorani, A Hofman, J Hui, J Hung, B Isomaa, PR Johnson, T Jørgensen, A Jula, M Kaakinen, J Kaprio, YA Kesaniemi, M Kivimaki, B Knight, S Koskinen, P Kovacs, KO Kyvik, GM Lathrop, DA Lawlor, O Le Bacquer, C Lecoeur, Y Li, V Lyssenko, R Mahley, M Mangino, AK Manning, MT MartÃnez-Larrad, JB McAteer, LJ McCulloch, R McPherson, C Meisinger, D Melzer, D Meyre, BD Mitchell, MA Morken, S Mukherjee, S Naitza, N Narisu, MJ Neville, BA Oostra, M Orrù, R Pakyz, CN Palmer, G Paolisso, C Pattaro, D Pearson, JF Peden, NL Pedersen, M Perola, AF Pfeiffer, I Pichler, O Polasek, D Posthuma, SC Potter, A Pouta, MA Province, BM Psaty, W Rathmann, NW Rayner, K Rice, S Ripatti, F Rivadeneira, M Roden, O Rolandsson, A Sandbaek, M Sandhu, S Sanna, AA Sayer, P Scheet, LJ Scott, U Seedorf, SJ Sharp, B Shields, G Sigurethsson, EJ Sijbrands, A Silveira, L Simpson, A Singleton, NL Smith, U Sovio, A Swift, H Syddall, AC Syvänen, T Tanaka, B Thorand, J Tichet, A Tönjes, T Tuomi, AG Uitterlinden, KW van Dijk, M van Hoek, D Varma, S Visvikis-Siest, V Vitart, N Vogelzangs, G Waeber, PJ Wagner, A Walley, GB Walters, KL Ward, H Watkins, MN Weedon, SH Wild, G Willemsen, JC Witteman, JW Yarnell, E Zeggini, D Zelenika, B Zethelius, G Zhai, JH Zhao, MC Zillikens, IB Borecki, RJ Loos, P Meneton, PK Magnusson, DM Nathan, GH Williams, AT Hattersley, K Silander, V Salomaa, GD Smith, SR Bornstein, P Schwarz, J Spranger, F Karpe, AR Shuldiner, C Cooper, GV Dedoussis, M Serrano-RÃos, AD Morris, L Lind, LJ Palmer, FB Hu, PW Franks, S Ebrahim, M Marmot, WH Kao, JS Pankow, MJ Sampson, J Kuusisto, M Laakso, T Hansen, O Pedersen, PP Pramstaller, HE Wichmann, T Illig, I Rudan, AF Wright, M Stumvoll, H Campbell, JF Wilson, RN Bergman, TA Buchanan, FS Collins, KL Mohlke, J Tuomilehto, TT Valle, D Altshuler, JI Rotter, DS Siscovick, BW Penninx, DI Boomsma, P Deloukas, TD Spector, TM Frayling, L Ferrucci, A Kong, U Thorsteinsdottir, K Stefansson, CM van Duijn, YS Aulchenko, A Cao, A Scuteri, D Schlessinger, M Uda, A Ruokonen, MR Jarvelin, DM Waterworth, P Vollenweider, L Peltonen, V Mooser, GR Abecasis, NJ Wareham, R Sladek, P Froguel, RM Watanabe, JB Meigs, L Groop, M Boehnke, MI McCarthy, JC Florez, I Barroso
Striatum Gene Expression Correlates for LOC_CHCL_ADIST_3 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The LOC_CHCL_ADIST_3 measures Cocaine TOTAL locomotion ( cm in 1 hr) under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for MORPH_ADIST_2 measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The MORPH_ADIST_2 measures Morphine Open Field TOTAL distance (cm) travelled under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for VERCNT180 measured in BXD RI Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The VERCNT180 measures Morphine vertical activity counts minutes 165-180 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for METH responses for home cage activity on Chr16 at Comt (22.04 Mbp , Build 37)
Description:
METH responses for home cage activity spans 0.00 - 47.04 Mbp (NCBI Build 37) on Chr16. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol preference locus on Chr16 at D16Xrf580 (59.71 Mbp , Build 37)
Description:
alcohol preference locus spans 34.71 - 84.71 Mbp (NCBI Build 37) on Chr16. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'Magnesium' (D008274). Incorporates data from 5 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Tretinoin' (D014212). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Bos taurus that interact with the MeSH term 'Colforsin' (D005576). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Carbamazepine' (D002220). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Platichthys flesus that interact with the MeSH term 'Cadmium Chloride' (D019256). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with nan that interact with the MeSH term 'Lithium' (D008094). Incorporates data from 120 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Calcium' (D002118). Incorporates data from 9 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with nan that interact with the MeSH term 'SK&F 82958' (C071262). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Silicon Dioxide' (D012822). Incorporates data from 9 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
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