QTL for METH responses for chewing on ChrX at DXNcvs10 (74.58 Mbp , Build 37)
Description:
METH responses for chewing spans 49.58 - 99.58 Mbp (NCBI Build 37) on ChrX. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Using a computational approach binding sites for these transcription factors within the promoter regions of annotated genes in the mouse, rat, and human genomes were identified. Combining a robust search algorithm to identify discrete binding sites, a comparison of targets across species, and an analysis of binding site locations within promoter regions, allowed fro the identification of candidate genes that are strong CREB- or zif268 targets and are thus regulated by neural activity.
Kyoto Encyclopedia of Genes and Genomes (KEGG) Geneset. This geneset contains genes that participate in the "Glucagon signaling pathway" pathway. This set was automatically constructed using the KEGG API and enumerating all mouse pathways.
gene2kegg v. 0.1.1
Last updated 2015.09.10
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