Publication Details

Essential role of the histone methyltransferase G9a in cocaine-induced plasticity.

8 GeneSets from this Publication:

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	GS86428: Table S4: Effect of G9a overexpression on genes that display increased mRNA induction in NAc following repeated cocaine. [DRG] provisional Figure Label: Chronic cocaine - Cocaine vs. Saline Species: Mus musculus  Data Points: 3  Description: Chronic cocaine - Cocaine vs. Saline Viral vectors followed by DNA microarray Change in gene expression Mice received intra-Nucleus accumbens injections of herpes simplex virus (HSV) vectors expressing green fluorescent protein (GFP). Following HSV-GFP infection, mice were treated with saline (5 treatments saline, intraperitoneal) or repeated cocaine (5 treatments 20 mg / kg cocaine-HCl, intraperitoneal) over the course of 3 days. Significance was determined using student?s t tests. P < 0.05. (NIF Table ID 403 [228]) Available to: Everyone (Tier I)
	GS86697: Table S4: Effect of G9a overexpression on genes that display increased mRNA induction in NAc following repeated cocaine. [DRG] provisional Figure Label: Chronic cocaine - Herpes simplex virus (HSV) vector - G9a vs. Herpes simplex virus (HSV) vector - green fluorescent protein (GFP) Species: Mus musculus  Data Points: 3  Description: Chronic cocaine - Herpes simplex virus (HSV) vector - G9a vs. Herpes simplex virus (HSV) vector - green fluorescent protein (GFP) Viral vectors followed by DNA microarray Change in gene expression Mice received intra-Nucleus accumbens injections of herpes simplex virus (HSV) vectors expressing either green fluorescent protein (GFP) or G9a. Following HSV-GFP and HSV-G9a-GFP infection, mice were treated with repeated cocaine (5 treatments 20 mg / kg cocaine-HCl, intraperitoneal) over the course of 3 days. Significance was determined using student?s t tests. P is less than or equal to 0.05. (NIF Table ID 403 [229]) Available to: Everyone (Tier I)
	GS86752: Table S3: Gene List: Repeated WD + Acute (217 Genes) [DRG] provisional Figure Label: Acute cocaine - Cocaine vs. Saline Species: Mus musculus  Data Points: 3  Description: Acute cocaine - Cocaine vs. Saline DNA microarray Change in gene expression Animals were treated daily with either saline (15 treatments saline, intraperitoneal) or acute cocaine (14 treatments saline + 1 treatment 20 mg / kg cocaine-HCl, intraperitoneal) and were sacrificed 1 hour after the final treatment. GeneSpring software Genelists were generated using significance criteria of a 1.3 fold change cutoff coupled with a nonstringent p-value cutoff of p < 0.05. (NIF Table ID 402 [225]) Available to: Everyone (Tier I)
	GS86990: Table S3: Gene List: Repeated WD + Acute (217 Genes) [DRG] provisional Figure Label: Cocaine withdrawal followed by acute cocaine - Cocaine vs. Saline Species: Mus musculus  Data Points: 1  Description: Cocaine withdrawal followed by acute cocaine - Cocaine vs. Saline DNA microarray Change in gene expression Animals were treated daily with either saline (15 treatments saline, intraperitoneal) or repeated withdrawal + acute cocaine (7 treatments 20 mg / kg cocaine-HCl + 7 treatments saline + 1 challenge treatment 20 mg / kg cocaine-HCl, intraperitoneal) and were sacrificed 1 hour after the final treatment. GeneSpring software Genelists were generated using significance criteria of a 1.3 fold change cutoff coupled with a nonstringent p-value cutoff of p < 0.05. (NIF Table ID 402 [227]) Available to: Everyone (Tier I)
	GS87018: Table S3: Gene List: Repeated WD + Acute (217 Genes) [DRG] provisional Figure Label: Chronic cocaine - Cocaine vs. Saline Species: Mus musculus  Data Points: 1  Description: Chronic cocaine - Cocaine vs. Saline DNA microarray Change in gene expression Animals were treated daily with either saline (15 treatments saline, intraperitoneal) or repeated + acute cocaine (7 treatments saline + 8 treatments 20 mg / kg cocaine-HCl, intraperitoneal) and were sacrificed 1 hour after the final treatment. GeneSpring software Genelists were generated using significance criteria of a 1.3 fold change cutoff coupled with a nonstringent p-value cutoff of p < 0.05. (NIF Table ID 402 [226]) Available to: Everyone (Tier I)
	GS87568: Table S3: Gene List: Repeated WD + Acute (217 Genes) (Whole Table) [DRG] provisional Figure Label: Acute cocaine - Cocaine vs. Saline Species: Mus musculus  Data Points: 3  Description: Acute cocaine - Cocaine vs. Saline DNA microarray Change in gene expression Animals were treated daily with either saline (15 treatments saline, intraperitoneal) or acute cocaine (14 treatments saline + 1 treatment 20 mg / kg cocaine-HCl, intraperitoneal) and were sacrificed 1 hour after the final treatment. GeneSpring software Genelists were generated using significance criteria of a 1.3 fold change cutoff coupled with a nonstringent p-value cutoff of p < 0.05. (NIF Method ID 225) Available to: Everyone (Tier I)
	GS87571: Table S4: Effect of G9a overexpression on genes that display increased mRNA induction in NAc following repeated cocaine. (Whole Table) [DRG] provisional Figure Label: Chronic cocaine - Cocaine vs. Saline Species: Mus musculus  Data Points: 3  Description: Chronic cocaine - Cocaine vs. Saline Viral vectors followed by DNA microarray Change in gene expression Mice received intra-Nucleus accumbens injections of herpes simplex virus (HSV) vectors expressing green fluorescent protein (GFP). Following HSV-GFP infection, mice were treated with saline (5 treatments saline, intraperitoneal) or repeated cocaine (5 treatments 20 mg / kg cocaine-HCl, intraperitoneal) over the course of 3 days. Significance was determined using student?s t tests. P < 0.05. (NIF Method ID 228) Available to: Everyone (Tier I)
	GS87572: Table S4: Effect of G9a overexpression on genes that display increased mRNA induction in NAc following repeated cocaine. (Whole Table) [DRG] provisional Figure Label: Chronic cocaine - Herpes simplex virus (HSV) vector - G9a vs. Herpes simplex virus (HSV) vector - green fluorescent protein (GFP) Species: Mus musculus  Data Points: 3  Description: Chronic cocaine - Herpes simplex virus (HSV) vector - G9a vs. Herpes simplex virus (HSV) vector - green fluorescent protein (GFP) Viral vectors followed by DNA microarray Change in gene expression Mice received intra-Nucleus accumbens injections of herpes simplex virus (HSV) vectors expressing either green fluorescent protein (GFP) or G9a. Following HSV-GFP and HSV-G9a-GFP infection, mice were treated with repeated cocaine (5 treatments 20 mg / kg cocaine-HCl, intraperitoneal) over the course of 3 days. Significance was determined using student?s t tests. P is less than or equal to 0.05. (NIF Method ID 229) Available to: Everyone (Tier I)
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