Publication Details

Gene expression in human alcoholism: microarray analysis of frontal cortex.

4 GeneSets from this Publication:

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	GS87255: Table 2: Myelin-Related Expression Data (Whole Table) [DRG] provisional Figure Label: Chronic ethanol - Ethanol vs. Control Species: Homo sapiens  Data Points: 7  Description: Chronic ethanol - Ethanol vs. Control DNA microarray Change in gene expression Control and alcoholic cases were divided on the basis of alcohol intake. In accordance with National Health and Medical Research Council (NHMRC) / World Health Organization criteria, alcoholism was defined by an average daily intake of greater than 80 g of ethanol; many of our cases had consumed over 200 g ethanol per day for most of their adult lives (usually > 30 years). All controls were teetotalers or social drinkers who consumed less (usually, much less) than 20 g of ethanol per day on aver GEMTools (Incyte Pharmaceuticals, Palo Alto, CA) Genes that showed a 1.4-fold increase or decrease in expression in the alcoholics versus controls. (NIF Method ID 158) Available to: Everyone (Tier I)
	GS87256: Table 2: Myelin-Related Expression Data (Whole Table) [DRG] provisional Figure Label: Chronic ethanol - Ethanol vs. Control Species: Homo sapiens  Data Points: 9  Description: Chronic ethanol - Ethanol vs. Control DNA microarray Change in gene expression Control and alcoholic cases were divided on the basis of alcohol intake. In accordance with National Health and Medical Research Council (NHMRC) / World Health Organization criteria, alcoholism was defined by an average daily intake of greater than 80 g of ethanol; many of our cases had consumed over 200 g ethanol per day for most of their adult lives (usually > 30 years). All controls were teetotalers or social drinkers who consumed less (usually, much less) than 20 g of ethanol per day on aver GEMTools (Incyte Pharmaceuticals, Palo Alto, CA) Genes that showed a 1.4-fold increase or decrease in expression in the alcoholics versus controls. (NIF Method ID 159) Available to: Everyone (Tier I)
	GS87257: Table 2: Myelin-Related Expression Data (Whole Table) [DRG] provisional Figure Label: Chronic ethanol - Ethanol vs. Control Species: Homo sapiens  Data Points: 10  Description: Chronic ethanol - Ethanol vs. Control DNA microarray Change in gene expression Control and alcoholic cases were divided on the basis of alcohol intake. In accordance with National Health and Medical Research Council (NHMRC) / World Health Organization criteria, alcoholism was defined by an average daily intake of greater than 80 g of ethanol; many of our cases had consumed over 200 g ethanol per day for most of their adult lives (usually > 30 years). All controls were teetotalers or social drinkers who consumed less (usually, much less) than 20 g of ethanol per day on aver GeneChip Software 3.1 (Affymetrix); matrix-based decision algorithm We selected genes represented by at least 10 probe pairs on the arrays, whose expression levels differed from the control by at least 1.4-fold in both comparison files. (NIF Method ID 160) Available to: Everyone (Tier I)
	GS87258: Table 2: Myelin-Related Expression Data (Whole Table) [DRG] provisional Figure Label: Chronic ethanol - Ethanol vs. Control Species: Homo sapiens  Data Points: 8  Description: Chronic ethanol - Ethanol vs. Control DNA microarray Change in gene expression Control and alcoholic cases were divided on the basis of alcohol intake. In accordance with National Health and Medical Research Council (NHMRC) / World Health Organization criteria, alcoholism was defined by an average daily intake of greater than 80 g of ethanol; many of our cases had consumed over 200 g ethanol per day for most of their adult lives (usually > 30 years). All controls were teetotalers or social drinkers who consumed less (usually, much less) than 20 g of ethanol per day on aver GeneChip Software 3.1 (Affymetrix); matrix-based decision algorithm We selected genes represented by at least 10 probe pairs on the arrays, whose expression levels differed from the control by at least 1.4-fold in both comparison files. (NIF Method ID 161) Available to: Everyone (Tier I)
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