Gene Details

USP9Y and homologs in 2 species are found in 145 GeneSets:

- Entrez   - Ensembl   - GeneNetwork   - STRING   - Comparative Toxicogenomics Database  

Select gene sets below using the check boxes, and then add them to a project using the pull down below. You can also create a project using the pull down. To view a set, click on the GeneSetID:GeneSet Description shown in green below.

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	GS194038: GO:1901362 organic cyclic compound biosynthetic process Figure Label: GO:1901362 Species: Homo sapiens  Data Points: 3737  Description: "The chemical reactions and pathways resulting in the formation of organic cyclic compound." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS201949: GO:0044699 single-organism process Figure Label: GO:0044699 Species: Homo sapiens  Data Points: 7638  Description: "A biological process that involves only one organism." [GOC:jl] Available to: Everyone (Tier I)
	GS208954: GO:0006139 nucleobase-containing compound metabolic process Figure Label: GO:0006139 Species: Homo sapiens  Data Points: 5216  Description: "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:ai] Available to: Everyone (Tier I)
	GS36868: Cerebellum Gene expression correlates of Percentage of entries into open arms of plus maze in Males BXD Figure Label: CBL PCT_ENTRIES_OPEN M BXD M430 RMA Species: Mus musculus  Data Points: 31  Description: Cerebellum Gene Expression Correlates for PCT_ENTRIES_OPEN measured in BXD RI Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The PCT_ENTRIES_OPEN measures Percentage of entries into open arms of plus maze under the domain Porsolt. The correlates were thresholded at a p-value of less than 0.001. Available to: Everyone (Tier II)
	GS198861: GO:0007167 enzyme linked receptor protein signaling pathway Figure Label: GO:0007167 Species: Homo sapiens  Data Points: 871  Description: "Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling, ISBN:0185316194] Available to: Everyone (Tier I)
	GS206525: GO:0044257 cellular protein catabolic process Figure Label: GO:0044257 Species: Homo sapiens  Data Points: 425  Description: "The chemical reactions and pathways resulting in the breakdown of a protein by individual cells." [GOC:jl] Available to: Everyone (Tier I)
	GS210180: GO:0031326 regulation of cellular biosynthetic process Figure Label: GO:0031326 Species: Homo sapiens  Data Points: 3324  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] Available to: Everyone (Tier I)
	GS188685: GO:0070011 peptidase activity, acting on L-amino acid peptides Figure Label: GO:0070011 Species: Mus musculus  Data Points: 571  Description: "Catalysis of the hydrolysis of peptide bonds formed between L-amino acids." [GOC:mah] Available to: Everyone (Tier I)
	GS171901: HP:0010985 Gonosomal inheritance Figure Label: HP:0010985 Species: Homo sapiens  Data Points: 166  Description: "A mode of inheritance that is observed for traits related to a gene encoded on the sex chromosomes." [HPO:probinson] Available to: Everyone (Tier I)
	GS205622: GO:0009889 regulation of biosynthetic process Figure Label: GO:0009889 Species: Homo sapiens  Data Points: 3354  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] Available to: Everyone (Tier I)
	GS199635: GO:0005622 intracellular Figure Label: GO:0005622 Species: Homo sapiens  Data Points: 12561  Description: "The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS193268: GO:0005575 cellular_component Figure Label: GO:0005575 Species: Mus musculus  Data Points: 23784  Description: "The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together." [GOC:go_curators] Available to: Everyone (Tier I)
	GS208061: GO:0010556 regulation of macromolecule biosynthetic process Figure Label: GO:0010556 Species: Homo sapiens  Data Points: 3199  Description: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS196943: GO:0008152 metabolic process Figure Label: GO:0008152 Species: Homo sapiens  Data Points: 9471  Description: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684] Available to: Everyone (Tier I)
	GS209215: GO:0007166 cell surface receptor signaling pathway Figure Label: GO:0007166 Species: Homo sapiens  Data Points: 2317  Description: "A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:mah, GOC:pr, GOC:signaling] Available to: Everyone (Tier I)
	GS171832: HP:0000118 Phenotypic abnormality Figure Label: HP:0000118 Species: Homo sapiens  Data Points: 2339  Description: "A phenotypic abnormality." [HPO:probinson] Available to: Everyone (Tier I)
	GS203072: GO:0090304 nucleic acid metabolic process Figure Label: GO:0090304 Species: Homo sapiens  Data Points: 4446  Description: "Any cellular metabolic process involving nucleic acids." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS195583: GO:0019953 sexual reproduction Figure Label: GO:0019953 Species: Homo sapiens  Data Points: 579  Description: "The regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times." [ISBN:0387520546] Available to: Everyone (Tier I)
	GS176718: HP:0000078 Abnormality of the genital system Figure Label: HP:0000078 Species: Homo sapiens  Data Points: 602  Description: "An abnormality of the `genital system` (FMA:7160)." [HPO:probinson] Available to: Everyone (Tier I)
	GS196941: GO:0008150 biological_process Figure Label: GO:0008150 Species: Homo sapiens  Data Points: 14623  Description: "Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end." [GOC:go_curators, GOC:isa_complete] Available to: Everyone (Tier I)
	GS203862: GO:0007283 spermatogenesis Figure Label: GO:0007283 Species: Homo sapiens  Data Points: 392  Description: "The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis." [GOC:jid, ISBN:9780878933846] Available to: Everyone (Tier I)
	GS208043: GO:0016788 hydrolase activity, acting on ester bonds Figure Label: GO:0016788 Species: Homo sapiens  Data Points: 741  Description: "Catalysis of the hydrolysis of any ester bond." [GOC:jl] Available to: Everyone (Tier I)
	GS199634: GO:0005623 cell Figure Label: GO:0005623 Species: Homo sapiens  Data Points: 14645  Description: "The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:go_curators] Available to: Everyone (Tier I)
	GS202188: GO:0044248 cellular catabolic process Figure Label: GO:0044248 Species: Homo sapiens  Data Points: 1668  Description: "The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:jl] Available to: Everyone (Tier I)
	GS209010: GO:1901575 organic substance catabolic process Figure Label: GO:1901575 Species: Homo sapiens  Data Points: 1852  Description: "The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie] Available to: Everyone (Tier I)
	GS208919: GO:0070647 protein modification by small protein conjugation or removal Figure Label: GO:0070647 Species: Homo sapiens  Data Points: 633  Description: "A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein." [GOC:mah] Available to: Everyone (Tier I)
	GS209989: GO:0051603 proteolysis involved in cellular protein catabolic process Figure Label: GO:0051603 Species: Homo sapiens  Data Points: 410  Description: "The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells." [GOC:ai, GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS194735: GO:0030163 protein catabolic process Figure Label: GO:0030163 Species: Homo sapiens  Data Points: 535  Description: "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:mah] Available to: Everyone (Tier I)
	GS195019: GO:0006511 ubiquitin-dependent protein catabolic process Figure Label: GO:0006511 Species: Homo sapiens  Data Points: 385  Description: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein." [GOC:go_curators] Available to: Everyone (Tier I)
	GS175135: HP:0000027 Azoospermia Figure Label: HP:0000027 Species: Homo sapiens  Data Points: 8  Description: "Absence of any measurable level of sperm in his semen." [HPO:probinson, pmid:20514278] Available to: Everyone (Tier I)
	GS207857: GO:0009058 biosynthetic process Figure Label: GO:0009058 Species: Homo sapiens  Data Points: 5223  Description: "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." [GOC:curators, ISBN:0198547684] Available to: Everyone (Tier I)
	GS200003: GO:0019941 modification-dependent protein catabolic process Figure Label: GO:0019941 Species: Homo sapiens  Data Points: 391  Description: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein." [GOC:go_curators] Available to: Everyone (Tier I)
	GS175526: HP:0000005 Mode of inheritance Figure Label: HP:0000005 Species: Homo sapiens  Data Points: 2121  Description: "The pattern in which a particular genetic trait or disorder is passed from one generation to the next." [HPO:probinson] Available to: Everyone (Tier I)
	GS204007: GO:0044700 single organism signaling Figure Label: GO:0044700 Species: Homo sapiens  Data Points: 4593  Description: "A signaling process occurring within a single organism." [GOC:jl] Available to: Everyone (Tier I)
	GS210182: GO:0031323 regulation of cellular metabolic process Figure Label: GO:0031323 Species: Homo sapiens  Data Points: 4377  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] Available to: Everyone (Tier I)
	GS199468: GO:0006508 proteolysis Figure Label: GO:0006508 Species: Homo sapiens  Data Points: 948  Description: "The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds." [GOC:bf, GOC:mah] Available to: Everyone (Tier I)
	GS196930: GO:0065007 biological regulation Figure Label: GO:0065007 Species: Homo sapiens  Data Points: 8622  Description: "Any process that modulates a measurable attribute of any biological process, quality or function." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] Available to: Everyone (Tier I)
	GS200312: GO:0019219 regulation of nucleobase-containing compound metabolic process Figure Label: GO:0019219 Species: Homo sapiens  Data Points: 3401  Description: "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] Available to: Everyone (Tier I)
	GS201431: GO:0005515 protein binding Figure Label: GO:0005515 Species: Homo sapiens  Data Points: 7336  Description: "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] Available to: Everyone (Tier I)
	GS192512: GO:0003824 catalytic activity Figure Label: GO:0003824 Species: Mus musculus  Data Points: 5103  Description: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS170997: HP:0000080 Abnormality of genital physiology Figure Label: HP:0000080 Species: Homo sapiens  Data Points: 98  Description: "An `abnormal` (PATO:0000460) `functionality` (PATO:0001509) of the `genital system` (FMA:7160)." [HPO:probinson] Available to: Everyone (Tier I)
	GS201023: GO:0071704 organic substance metabolic process Figure Label: GO:0071704 Species: Homo sapiens  Data Points: 9005  Description: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [CHEBI:50860, GOC:mah] Available to: Everyone (Tier I)
	GS204468: GO:0043632 modification-dependent macromolecule catabolic process Figure Label: GO:0043632 Species: Homo sapiens  Data Points: 394  Description: "The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule." [GOC:jl] Available to: Everyone (Tier I)
	GS196595: GO:0006464 cellular protein modification process Figure Label: GO:0006464 Species: Homo sapiens  Data Points: 2464  Description: "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." [GOC:go_curators] Available to: Everyone (Tier I)
	GS206108: GO:2001141 regulation of RNA biosynthetic process Figure Label: GO:2001141 Species: Homo sapiens  Data Points: 2896  Description: "Any process that modulates the frequency, rate or extent of RNA biosynthetic process." [GOC:dph] Available to: Everyone (Tier I)
	GS195214: GO:0009987 cellular process Figure Label: GO:0009987 Species: Homo sapiens  Data Points: 12850  Description: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete] Available to: Everyone (Tier I)
	GS204204: GO:0006351 transcription, DNA-dependent Figure Label: GO:0006351 Species: Homo sapiens  Data Points: 3201  Description: "The cellular synthesis of RNA on a template of DNA." [GOC:jl, GOC:txnOH] Available to: Everyone (Tier I)
	GS184566: GO:0019538 protein metabolic process Figure Label: GO:0019538 Species: Mus musculus  Data Points: 3548  Description: "The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification." [GOC:ma] Available to: Everyone (Tier I)
	GS199124: GO:0051716 cellular response to stimulus Figure Label: GO:0051716 Species: Homo sapiens  Data Points: 4983  Description: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." [GOC:bf, GOC:jl] Available to: Everyone (Tier I)
	GS200363: GO:0004843 ubiquitin-specific protease activity Figure Label: GO:0004843 Species: Homo sapiens  Data Points: 46  Description: "Catalysis of the hydrolysis of various forms of polymeric ubiquitin sequences." [ISBN:0120793709] Available to: Everyone (Tier I)
	GS200648: GO:0044260 cellular macromolecule metabolic process Figure Label: GO:0044260 Species: Homo sapiens  Data Points: 6651  Description: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS182209: GO:0008233 peptidase activity Figure Label: GO:0008233 Species: Mus musculus  Data Points: 600  Description: "Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid." [GOC:jl, ISBN:0815332181] Available to: Everyone (Tier I)
	GS204746: GO:0080090 regulation of primary metabolic process Figure Label: GO:0080090 Species: Homo sapiens  Data Points: 4314  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [PMID:19211694] Available to: Everyone (Tier I)
	GS205544: GO:0070011 peptidase activity, acting on L-amino acid peptides Figure Label: GO:0070011 Species: Homo sapiens  Data Points: 558  Description: "Catalysis of the hydrolysis of peptide bonds formed between L-amino acids." [GOC:mah] Available to: Everyone (Tier I)
	GS197244: GO:0044237 cellular metabolic process Figure Label: GO:0044237 Species: Homo sapiens  Data Points: 8595  Description: "The chemical reactions and pathways by which individual cells transform chemical substances." [GOC:go_curators] Available to: Everyone (Tier I)
	GS207925: GO:0034645 cellular macromolecule biosynthetic process Figure Label: GO:0034645 Species: Homo sapiens  Data Points: 4169  Description: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS201251: GO:0044424 intracellular part Figure Label: GO:0044424 Species: Homo sapiens  Data Points: 12234  Description: "Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [GOC:jl] Available to: Everyone (Tier I)
	GS203642: GO:0006725 cellular aromatic compound metabolic process Figure Label: GO:0006725 Species: Homo sapiens  Data Points: 5379  Description: "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells." [GOC:ai, ISBN:0198506732] Available to: Everyone (Tier I)
	GS198456: GO:0019438 aromatic compound biosynthetic process Figure Label: GO:0019438 Species: Homo sapiens  Data Points: 3626  Description: "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai] Available to: Everyone (Tier I)
	GS199006: GO:0008233 peptidase activity Figure Label: GO:0008233 Species: Homo sapiens  Data Points: 580  Description: "Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid." [GOC:jl, ISBN:0815332181] Available to: Everyone (Tier I)
	GS203908: GO:0016070 RNA metabolic process Figure Label: GO:0016070 Species: Homo sapiens  Data Points: 3917  Description: "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS207923: GO:0034641 cellular nitrogen compound metabolic process Figure Label: GO:0034641 Species: Homo sapiens  Data Points: 5601  Description: "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." [GOC:mah] Available to: Everyone (Tier I)
	GS209667: GO:0046332 SMAD binding Figure Label: GO:0046332 Species: Homo sapiens  Data Points: 63  Description: "Interacting selectively and non-covalently with a SMAD signaling protein." [GOC:ai] Available to: Everyone (Tier I)
	GS204612: GO:0019222 regulation of metabolic process Figure Label: GO:0019222 Species: Homo sapiens  Data Points: 4811  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] Available to: Everyone (Tier I)
	GS175137: HP:0000025 Functional abnormality of male internal genitalia Figure Label: HP:0000025 Species: Homo sapiens  Data Points: 31  Description: Functional abnormality of male internal genitalia Available to: Everyone (Tier I)
	GS198263: GO:0005488 binding Figure Label: GO:0005488 Species: Homo sapiens  Data Points: 11955  Description: "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." [GOC:ceb, GOC:mah, ISBN:0198506732] Available to: Everyone (Tier I)
	GS202080: GO:0051252 regulation of RNA metabolic process Figure Label: GO:0051252 Species: Homo sapiens  Data Points: 2957  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] Available to: Everyone (Tier I)
	GS194040: GO:1901360 organic cyclic compound metabolic process Figure Label: GO:1901360 Species: Homo sapiens  Data Points: 5558  Description: "The chemical reactions and pathways involving organic cyclic compound." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS206355: GO:0023052 signaling Figure Label: GO:0023052 Species: Homo sapiens  Data Points: 4593  Description: "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." [GOC:mtg_signal, GOC:mtg_signaling_feb11, GOC:signaling] Available to: Everyone (Tier I)
	GS175529: HP:0000001 All Figure Label: HP:0000001 Species: Homo sapiens  Data Points: 2374  Description: All Available to: Everyone (Tier I)
	GS209199: GO:0007165 signal transduction Figure Label: GO:0007165 Species: Homo sapiens  Data Points: 4084  Description: "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11] Available to: Everyone (Tier I)
	GS208037: GO:0016787 hydrolase activity Figure Label: GO:0016787 Species: Homo sapiens  Data Points: 2353  Description: "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS205266: GO:0032774 RNA biosynthetic process Figure Label: GO:0032774 Species: Homo sapiens  Data Points: 3287  Description: "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers." [GOC:mah] Available to: Everyone (Tier I)
	GS195977: GO:0007154 cell communication Figure Label: GO:0007154 Species: Homo sapiens  Data Points: 4719  Description: "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:mah] Available to: Everyone (Tier I)
	GS204627: GO:0007179 transforming growth factor beta receptor signaling pathway Figure Label: GO:0007179 Species: Homo sapiens  Data Points: 167  Description: "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling] Available to: Everyone (Tier I)
	GS182219: GO:0008234 cysteine-type peptidase activity Figure Label: GO:0008234 Species: Mus musculus  Data Points: 137  Description: "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE] Available to: Everyone (Tier I)
	GS207862: GO:0009056 catabolic process Figure Label: GO:0009056 Species: Homo sapiens  Data Points: 1993  Description: "The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." [ISBN:0198547684] Available to: Everyone (Tier I)
	GS204021: GO:0044707 single-multicellular organism process Figure Label: GO:0044707 Species: Homo sapiens  Data Points: 5605  Description: "A biological process occurring within a single, multicellular organism." [GOC:jl] Available to: Everyone (Tier I)
	GS173984: HP:0001450 Y-linked inheritance Figure Label: HP:0001450 Species: Homo sapiens  Data Points: 6  Description: "A mode of inheritance that is observed for traits related to a gene encoded on the Y chromosome." [HPO:curators] Available to: Everyone (Tier I)
	GS205047: GO:0006807 nitrogen compound metabolic process Figure Label: GO:0006807 Species: Homo sapiens  Data Points: 5962  Description: "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium." [CHEBI:51143, GOC:go_curators, GOC:jl, ISBN:0198506732] Available to: Everyone (Tier I)
	GS194267: GO:0043170 macromolecule metabolic process Figure Label: GO:0043170 Species: Homo sapiens  Data Points: 7311  Description: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS210357: GO:0044249 cellular biosynthetic process Figure Label: GO:0044249 Species: Homo sapiens  Data Points: 5047  Description: "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:jl] Available to: Everyone (Tier I)
	GS209863: GO:0050896 response to stimulus Figure Label: GO:0050896 Species: Homo sapiens  Data Points: 6585  Description: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." [GOC:ai, GOC:bf] Available to: Everyone (Tier I)
	GS124579: Selenium interacting genes (MeSH:D012643) in CTD Figure Label: D012643 [CTD] Species: Homo sapiens  Data Points: 1522  Description: Genes that interact with the MeSH term 'Selenium' (D012643). Incorporates data from 125 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene. Available to: Everyone (Tier I)
	GS203607: GO:0034654 nucleobase-containing compound biosynthetic process Figure Label: GO:0034654 Species: Homo sapiens  Data Points: 3573  Description: "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah] Available to: Everyone (Tier I)
	GS208920: GO:0070646 protein modification by small protein removal Figure Label: GO:0070646 Species: Homo sapiens  Data Points: 77  Description: "A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein." [GOC:mah] Available to: Everyone (Tier I)
	GS206953: GO:0018130 heterocycle biosynthetic process Figure Label: GO:0018130 Species: Homo sapiens  Data Points: 3640  Description: "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198547684] Available to: Everyone (Tier I)
	GS199499: GO:0051171 regulation of nitrogen compound metabolic process Figure Label: GO:0051171 Species: Homo sapiens  Data Points: 3487  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] Available to: Everyone (Tier I)
	GS199016: GO:0008234 cysteine-type peptidase activity Figure Label: GO:0008234 Species: Homo sapiens  Data Points: 147  Description: "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE] Available to: Everyone (Tier I)
	GS194499: GO:0044271 cellular nitrogen compound biosynthetic process Figure Label: GO:0044271 Species: Homo sapiens  Data Points: 3721  Description: "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732] Available to: Everyone (Tier I)
	GS196811: GO:0032504 multicellular organism reproduction Figure Label: GO:0032504 Species: Homo sapiens  Data Points: 637  Description: "The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:isa_complete, GOC:jid] Available to: Everyone (Tier I)
	GS180164: GO:0008150 biological_process Figure Label: GO:0008150 Species: Mus musculus  Data Points: 23855  Description: "Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end." [GOC:go_curators, GOC:isa_complete] Available to: Everyone (Tier I)
	GS207863: GO:0009057 macromolecule catabolic process Figure Label: GO:0009057 Species: Homo sapiens  Data Points: 890  Description: "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS199937: GO:0030509 BMP signaling pathway Figure Label: GO:0030509 Species: Homo sapiens  Data Points: 109  Description: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, ISBN:0878932437, PR:000000034] Available to: Everyone (Tier I)
	GS208575: GO:0044265 cellular macromolecule catabolic process Figure Label: GO:0044265 Species: Homo sapiens  Data Points: 692  Description: "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells." [CHEBI:33694, GOC:jl] Available to: Everyone (Tier I)
	GS177531: GO:0043170 macromolecule metabolic process Figure Label: GO:0043170 Species: Mus musculus  Data Points: 6435  Description: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS185585: GO:0044710 single-organism metabolic process Figure Label: GO:0044710 Species: Mus musculus  Data Points: 8414  Description: "A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism." [GOC:jl] Available to: Everyone (Tier I)
	GS205255: GO:0044238 primary metabolic process Figure Label: GO:0044238 Species: Homo sapiens  Data Points: 8702  Description: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] Available to: Everyone (Tier I)
	GS210526: GO:0019783 small conjugating protein-specific protease activity Figure Label: GO:0019783 Species: Homo sapiens  Data Points: 52  Description: "Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated." [GOC:ma, GOC:mah] Available to: Everyone (Tier I)
	GS171833: HP:0000119 Abnormality of the genitourinary system Figure Label: HP:0000119 Species: Homo sapiens  Data Points: 990  Description: "The presence of any abnormality of the `genitourinary system` (FMA:280610)." [HPO:curators] Available to: Everyone (Tier I)
	GS35366: Cerebellum Gene expression correlates of Amount of time in open arms of plus maze in Females & Males BXD Figure Label: CBL TIME_OPEN_SAL F&M BXD M430 RMA Species: Mus musculus  Data Points: 33  Description: Cerebellum Gene Expression Correlates for TIME_OPEN_SAL measured in BXD RI Females & Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The TIME_OPEN_SAL measures Amount of time in open arms of plus maze under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001. Available to: Everyone (Tier II)
	GS207858: GO:0009059 macromolecule biosynthetic process Figure Label: GO:0009059 Species: Homo sapiens  Data Points: 4276  Description: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS195577: GO:0016790 thiolester hydrolase activity Figure Label: GO:0016790 Species: Homo sapiens  Data Points: 105  Description: "Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A." [http://www.onelook.com] Available to: Everyone (Tier I)
	GS208012: GO:0044464 cell part Figure Label: GO:0044464 Species: Homo sapiens  Data Points: 14644  Description: "Any constituent part of a cell, the basic structural and functional unit of all organisms." [GOC:jl] Available to: Everyone (Tier I)
	GS207582: GO:0007276 gamete generation Figure Label: GO:0007276 Species: Homo sapiens  Data Points: 501  Description: "The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell." [GOC:ems, GOC:mtg_sensu] Available to: Everyone (Tier I)
	GS210212: GO:0005575 cellular_component Figure Label: GO:0005575 Species: Homo sapiens  Data Points: 17054  Description: "The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together." [GOC:go_curators] Available to: Everyone (Tier I)
	GS195291: GO:0006355 regulation of transcription, DNA-dependent Figure Label: GO:0006355 Species: Homo sapiens  Data Points: 2875  Description: "Any process that modulates the frequency, rate or extent of cellular DNA-dependent transcription." [GOC:go_curators, GOC:txnOH] Available to: Everyone (Tier I)
	GS201239: GO:0046483 heterocycle metabolic process Figure Label: GO:0046483 Species: Homo sapiens  Data Points: 5369  Description: "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [CHEBI:5686, ISBN:0198506732] Available to: Everyone (Tier I)
	GS205369: GO:0010468 regulation of gene expression Figure Label: GO:0010468 Species: Homo sapiens  Data Points: 3344  Description: "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS35458: Hippocampus Gene expression correlates of Difference in total distance traveled (cm) (saline-ethanol) in Females BXD Figure Label: HPC ACTITOT_DIFF F BXD M430v2 RMA Species: Mus musculus  Data Points: 31  Description: Hippocampus Gene Expression Correlates for ACTITOT_DIFF measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The ACTITOT_DIFF measures Difference in total distance traveled (cm) (saline-ethanol) under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001. Available to: Everyone (Tier II)
	GS188399: GO:0044238 primary metabolic process Figure Label: GO:0044238 Species: Mus musculus  Data Points: 7644  Description: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] Available to: Everyone (Tier I)
	GS206623: GO:0050794 regulation of cellular process Figure Label: GO:0050794 Species: Homo sapiens  Data Points: 7689  Description: "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators] Available to: Everyone (Tier I)
	GS206696: GO:0044702 single organism reproductive process Figure Label: GO:0044702 Species: Homo sapiens  Data Points: 1165  Description: "A biological process that directly contributes to the process of producing new individuals, involving a single organism." [GOC:jl] Available to: Everyone (Tier I)
	GS209455: GO:0003824 catalytic activity Figure Label: GO:0003824 Species: Homo sapiens  Data Points: 5321  Description: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS184218: GO:0071704 organic substance metabolic process Figure Label: GO:0071704 Species: Mus musculus  Data Points: 8072  Description: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [CHEBI:50860, GOC:mah] Available to: Everyone (Tier I)
	GS200602: GO:0044267 cellular protein metabolic process Figure Label: GO:0044267 Species: Homo sapiens  Data Points: 3254  Description: "The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification." [GOC:jl] Available to: Everyone (Tier I)
	GS193937: GO:0006366 transcription from RNA polymerase II promoter Figure Label: GO:0006366 Species: Homo sapiens  Data Points: 1393  Description: "The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs)." [GOC:jl, GOC:txnOH, ISBN:0321000382] Available to: Everyone (Tier I)
	GS35027: Cerebellum Gene expression correlates of Percentage of time into open arms of plus maze in Females & Males BXD Figure Label: CBL PCT_TIME_OPEN F&M BXD M430 RMA Species: Mus musculus  Data Points: 33  Description: Cerebellum Gene Expression Correlates for PCT_TIME_OPEN measured in BXD RI Females & Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The PCT_TIME_OPEN measures Percentage of time into open arms of plus maze under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001. Available to: Everyone (Tier II)
	GS205364: GO:0010467 gene expression Figure Label: GO:0010467 Species: Homo sapiens  Data Points: 4713  Description: "The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS204628: GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway Figure Label: GO:0007178 Species: Homo sapiens  Data Points: 267  Description: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling] Available to: Everyone (Tier I)
	GS201367: GO:0019538 protein metabolic process Figure Label: GO:0019538 Species: Homo sapiens  Data Points: 3885  Description: "The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification." [GOC:ma] Available to: Everyone (Tier I)
	GS209009: GO:1901576 organic substance biosynthetic process Figure Label: GO:1901576 Species: Homo sapiens  Data Points: 5152  Description: "The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie] Available to: Everyone (Tier I)
	GS207720: GO:0048609 multicellular organismal reproductive process Figure Label: GO:0048609 Species: Homo sapiens  Data Points: 637  Description: "The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs." [GOC:dph, GOC:jid, GOC:tb] Available to: Everyone (Tier I)
	GS196808: GO:0032501 multicellular organismal process Figure Label: GO:0032501 Species: Homo sapiens  Data Points: 5637  Description: "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb] Available to: Everyone (Tier I)
	GS35901: Cerebellum Gene expression correlates of Number of entries into open arms of plus maze in Males BXD Figure Label: CBL ENTRIES_OPEN M BXD M430 RMA Species: Mus musculus  Data Points: 31  Description: Cerebellum Gene Expression Correlates for ENTRIES_OPEN measured in BXD RI Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The ENTRIES_OPEN measures Number of entries into open arms of plus maze under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001. Available to: Everyone (Tier II)
	GS207991: GO:0000003 reproduction Figure Label: GO:0000003 Species: Homo sapiens  Data Points: 1597  Description: "The production by an organism of new individuals that contain some portion of their genetic material inherited from that organism." [GOC:go_curators, GOC:isa_complete, ISBN:0198506732] Available to: Everyone (Tier I)
	GS182673: GO:0006508 proteolysis Figure Label: GO:0006508 Species: Mus musculus  Data Points: 862  Description: "The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds." [GOC:bf, GOC:mah] Available to: Everyone (Tier I)
	GS202415: GO:0044710 single-organism metabolic process Figure Label: GO:0044710 Species: Homo sapiens  Data Points: 9213  Description: "A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism." [GOC:jl] Available to: Everyone (Tier I)
	GS127127: Benzo(a)pyrene interacting genes (MeSH:D001564) in CTD Figure Label: D001564 [CTD] Species: Homo sapiens  Data Points: 3171  Description: Genes that interact with the MeSH term 'Benzo(a)pyrene' (D001564). Incorporates data from 239 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene. Available to: Everyone (Tier I)
	GS206544: GO:2000112 regulation of cellular macromolecule biosynthetic process Figure Label: GO:2000112 Species: Homo sapiens  Data Points: 3118  Description: "Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process." [GOC:obol] Available to: Everyone (Tier I)
	GS204661: GO:0016579 protein deubiquitination Figure Label: GO:0016579 Species: Homo sapiens  Data Points: 64  Description: "The removal of one or more ubiquitin groups from a protein." [GOC:ai] Available to: Everyone (Tier I)
	GS199837: GO:0004221 ubiquitin thiolesterase activity Figure Label: GO:0004221 Species: Homo sapiens  Data Points: 74  Description: "Catalysis of the reaction: ubiquitin C-terminal thiolester + H2O = ubiquitin + a thiol. Hydrolysis of esters, including those formed between thiols such as dithiothreitol or glutathione and the C-terminal glycine residue of the polypeptide ubiquitin, and AMP-ubiquitin." [EC:3.1.2.15] Available to: Everyone (Tier I)
	GS202316: GO:0050789 regulation of biological process Figure Label: GO:0050789 Species: Homo sapiens  Data Points: 8137  Description: "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:ai, GOC:go_curators] Available to: Everyone (Tier I)
	GS194087: GO:0003674 molecular_function Figure Label: GO:0003674 Species: Homo sapiens  Data Points: 15286  Description: "Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions." [GOC:go_curators] Available to: Everyone (Tier I)
	GS194133: GO:0005737 cytoplasm Figure Label: GO:0005737 Species: Homo sapiens  Data Points: 9128  Description: "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] Available to: Everyone (Tier I)
	GS198360: GO:0006357 regulation of transcription from RNA polymerase II promoter Figure Label: GO:0006357 Species: Homo sapiens  Data Points: 1214  Description: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:go_curators, GOC:txnOH] Available to: Everyone (Tier I)
	GS196196: GO:0022414 reproductive process Figure Label: GO:0022414 Species: Homo sapiens  Data Points: 1592  Description: "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:dph, GOC:isa_complete] Available to: Everyone (Tier I)
	GS177356: GO:0003674 molecular_function Figure Label: GO:0003674 Species: Mus musculus  Data Points: 23365  Description: "Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions." [GOC:go_curators] Available to: Everyone (Tier I)
	GS199032: GO:0036211 protein modification process Figure Label: GO:0036211 Species: Homo sapiens  Data Points: 2464  Description: "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." [GOC:bf, GOC:jl] Available to: Everyone (Tier I)
	GS191129: GO:0016787 hydrolase activity Figure Label: GO:0016787 Species: Mus musculus  Data Points: 2190  Description: "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS205650: GO:0048232 male gamete generation Figure Label: GO:0048232 Species: Homo sapiens  Data Points: 393  Description: "Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction." [GOC:dph, GOC:jid] Available to: Everyone (Tier I)
	GS206329: GO:0060255 regulation of macromolecule metabolic process Figure Label: GO:0060255 Species: Homo sapiens  Data Points: 4151  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS205783: GO:0070410 co-SMAD binding Figure Label: GO:0070410 Species: Homo sapiens  Data Points: 11  Description: "Interacting selectively and non-covalently with a common mediator SMAD signaling protein." [GOC:BHF, GOC:vk, PMID:19114992] Available to: Everyone (Tier I)
	GS194336: GO:0043412 macromolecule modification Figure Label: GO:0043412 Species: Homo sapiens  Data Points: 2558  Description: "The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties." [GOC:go_curators] Available to: Everyone (Tier I)
	GS180166: GO:0008152 metabolic process Figure Label: GO:0008152 Species: Mus musculus  Data Points: 9049  Description: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684] Available to: Everyone (Tier I)
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