Gene Details

MMAA and homologs in 5 species are found in 249 GeneSets:

- Entrez   - Ensembl   - GeneNetwork   - STRING   - Comparative Toxicogenomics Database  

Select gene sets below using the check boxes, and then add them to a project using the pull down below. You can also create a project using the pull down. To view a set, click on the GeneSetID:GeneSet Description shown in green below.

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	GS204629: GO:1901564 organonitrogen compound metabolic process Figure Label: GO:1901564 Species: Homo sapiens  Data Points: 1684  Description: "The chemical reactions and pathways involving organonitrogen compound." [GOC:pr, GOC:TermGenie] Available to: Everyone (Tier I)
	GS185985: GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Figure Label: GO:0016818 Species: Mus musculus  Data Points: 641  Description: "Catalysis of the hydrolysis of any acid anhydride which contains phosphorus." [GOC:jl] Available to: Everyone (Tier I)
	GS205510: GO:0001883 purine nucleoside binding Figure Label: GO:0001883 Species: Homo sapiens  Data Points: 1839  Description: "Interacting selectively and non-covalently with a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose." [GOC:hjd] Available to: Everyone (Tier I)
	GS136137: lithogenic gene 18 (Lith18, Published QTL Chr 8) Figure Label: QTL-Lith18-Mouse-Chr 8 Species: Mus musculus  Data Points: 574  Description: QTL associated with lithogenic gene 18. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (95199416) Available to: Everyone (Tier I)
	GS189855: GO:0043168 anion binding Figure Label: GO:0043168 Species: Mus musculus  Data Points: 2260  Description: "Interacting selectively and non-covalently with anions, charged atoms or groups of atoms with a net negative charge." [GOC:jl] Available to: Everyone (Tier I)
	GS136045: insulin dependent diabetes susceptibility 22 (Idd22, Published QTL Chr 8) Figure Label: QTL-Idd22-Mouse-Chr 8 Species: Mus musculus  Data Points: 573  Description: QTL associated with insulin dependent diabetes susceptibility 22. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (90626802) Available to: Everyone (Tier I)
	GS202416: GO:0044711 single-organism biosynthetic process Figure Label: GO:0044711 Species: Homo sapiens  Data Points: 434  Description: "A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - involving a single organism." [GOC:jl] Available to: Everyone (Tier I)
	GS204242: GO:0006767 water-soluble vitamin metabolic process Figure Label: GO:0006767 Species: Homo sapiens  Data Points: 65  Description: "The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water." [GOC:jl] Available to: Everyone (Tier I)
	GS174134: HP:0002012 Abnormality of the abdominal organs Figure Label: HP:0002012 Species: Homo sapiens  Data Points: 845  Description: "An abnormality of the `viscera of the abdomen` (FMA:259123)." [HPO:probinson] Available to: Everyone (Tier I)
	GS135547: CD4 T cell subset 3 (Cd4ts3, Published QTL Chr 8) Figure Label: QTL-Cd4ts3-Mouse-Chr 8 Species: Mus musculus  Data Points: 573  Description: QTL associated with CD4 T cell subset 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (90920080) Available to: Everyone (Tier I)
	GS184984: GO:0032553 ribonucleotide binding Figure Label: GO:0032553 Species: Mus musculus  Data Points: 1774  Description: "Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] Available to: Everyone (Tier I)
	GS86911: Table S1: Additional data file 1 is a table listing the results of two-way ANOVA (FDR < 1%). Lists of probe sets and gene names altered by morphine treatment (661). [DRG] provisional Figure Label: Morphine: Chronic, Acute and Withdrawal - Morphine vs. Control Species: Mus musculus  Data Points: 612  Description: Morphine: Chronic, Acute and Withdrawal - Morphine vs. Control DNA microarray Change in gene expression Control and acute morphine groups received injections of saline in the same time schedule as the chronic group received morphine (thrice daily, 09:00 hours, 13:00 hours, and 17:00 hours, for 4 days using a dosing schedule of 10, 20, 40, and 40 mg / kg morphine on days 1, 2, 3, and 4, respectively). On day 5, acutely treated animals were injected with a single dose of morphine, 20 mg / kg at 09:00 hours, chronic group received 40 mg / kg, and control group received saline. Mice were killed by d Two-way analysis of variance (ANOVA). Morphine treatment altered the expression of 618 transcripts covered by 661 probe sets (false discovery rate [FDR] < 1%, rank > 3). (NIF Table ID 134.2 [84.2]) Available to: Everyone (Tier I)
	GS193268: GO:0005575 cellular_component Figure Label: GO:0005575 Species: Mus musculus  Data Points: 23784  Description: "The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together." [GOC:go_curators] Available to: Everyone (Tier I)
	GS194039: GO:1901363 heterocyclic compound binding Figure Label: GO:1901363 Species: Homo sapiens  Data Points: 5400  Description: "Interacting selectively and non-covalently with heterocyclic compound." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS183645: GO:0017076 purine nucleotide binding Figure Label: GO:0017076 Species: Mus musculus  Data Points: 1765  Description: "Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate." [GOC:ai] Available to: Everyone (Tier I)
	GS171194: HP:0001946 Ketosis Figure Label: HP:0001946 Species: Homo sapiens  Data Points: 28  Description: "Presence of elevated levels of ketone bodies in the body." [HPO:probinson] Available to: Everyone (Tier I)
	GS171902: HP:0010987 Abnormality of cellular immune system Figure Label: HP:0010987 Species: Homo sapiens  Data Points: 285  Description: "An abnormality of the morphology or counts of the cells that make up the `immune system` (FMA:9825)." [HPO:probinson] Available to: Everyone (Tier I)
	GS135948: HDL QTL 16 (Hdlq16, Published QTL Chr 8) Figure Label: QTL-Hdlq16-Mouse-Chr 8 Species: Mus musculus  Data Points: 574  Description: QTL associated with HDL QTL 16. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (95209247) Available to: Everyone (Tier I)
	GS176817: HP:0011446 Abnormality of higher mental function Figure Label: HP:0011446 Species: Homo sapiens  Data Points: 1213  Description: "Cognitive, psychiatric or memory anomaly." [DDD:ajackson] Available to: Everyone (Tier I)
	GS197443: GO:0032549 ribonucleoside binding Figure Label: GO:0032549 Species: Homo sapiens  Data Points: 1840  Description: "Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose." [GOC:mah] Available to: Everyone (Tier I)
	GS86515: Table S2: Additional data file 2 - Lists of probe sets of genes with expression altered by acute and chronic morphine (ANOVA; FDR < 1%). DBA/2J [DRG] provisional Figure Label: Acute morphine - Morphine vs. Saline Species: Mus musculus  Data Points: 349  Description: Acute morphine - Morphine vs. Saline DNA microarray Change in gene expression Control and acute morphine groups received injections of saline in the same time schedule as the chronic group received morphine (thrice daily, 09:00 hours, 13:00 hours, and 17:00 hours, for 4 days using a dosing schedule of 10, 20, 40, and 40 mg / kg morphine on days 1, 2, 3, and 4, respectively). On day 5, acutely treated animals were injected with a single dose of morphine, 20 mg / kg at 09:00 hours (chronic group received 40 mg / kg) and control group received saline. Mice were killed by de ANOVA; FDR < 1% The results were obtained using fold change (>1.2) of gene expression level compared with the saline control group. (NIF Table ID 136 [87]) Available to: Everyone (Tier I)
	GS136657: skeletal muscle weight 16 (Skmw16, Published QTL Chr 8) Figure Label: QTL-Skmw16-Mouse-Chr 8 Species: Mus musculus  Data Points: 501  Description: QTL associated with skeletal muscle weight 16. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (83463446) Available to: Everyone (Tier I)
	GS170783: HP:0010974 Abnormality of myeloid leukocytes Figure Label: HP:0010974 Species: Homo sapiens  Data Points: 120  Description: "An abnormality of `myeloid leukocytes` (CL:0000766)." [HPO:probinson] Available to: Everyone (Tier I)
	GS171243: HP:0003145 Decreased adenosylcobalamin Figure Label: HP:0003145 Species: Homo sapiens  Data Points: 5  Description: "Decreased concentration of `adenosylcobalamin` (CHEBI:18408). Adenosylcobalamin is one of the active forms of vitamin B12." [HPO:probinson] Available to: Everyone (Tier I)
	GS207857: GO:0009058 biosynthetic process Figure Label: GO:0009058 Species: Homo sapiens  Data Points: 5223  Description: "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." [GOC:curators, ISBN:0198547684] Available to: Everyone (Tier I)
	GS201023: GO:0071704 organic substance metabolic process Figure Label: GO:0071704 Species: Homo sapiens  Data Points: 9005  Description: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [CHEBI:50860, GOC:mah] Available to: Everyone (Tier I)
	GS136061: immunoregulatory 3 (Im3, Published QTL Chr 8) Figure Label: QTL-Im3-Mouse-Chr 8 Species: Mus musculus  Data Points: 445  Description: QTL associated with immunoregulatory 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (74230513) Available to: Everyone (Tier I)
	GS171893: HP:0011458 Abdominal symptom Figure Label: HP:0011458 Species: Homo sapiens  Data Points: 473  Description: Abdominal symptom Available to: Everyone (Tier I)
	GS196343: GO:0036094 small molecule binding Figure Label: GO:0036094 Species: Homo sapiens  Data Points: 2625  Description: "Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:pm] Available to: Everyone (Tier I)
	GS191106: GO:0044464 cell part Figure Label: GO:0044464 Species: Mus musculus  Data Points: 13186  Description: "Any constituent part of a cell, the basic structural and functional unit of all organisms." [GOC:jl] Available to: Everyone (Tier I)
	GS172054: HP:0001507 Growth abnormality Figure Label: HP:0001507 Species: Homo sapiens  Data Points: 954  Description: Growth abnormality Available to: Everyone (Tier I)
	GS210137: GO:0016462 pyrophosphatase activity Figure Label: GO:0016462 Species: Homo sapiens  Data Points: 790  Description: "Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments." [EC:3.6.1.-, GOC:curators] Available to: Everyone (Tier I)
	GS177404: GO:0005737 cytoplasm Figure Label: GO:0005737 Species: Mus musculus  Data Points: 8406  Description: "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] Available to: Everyone (Tier I)
	GS201251: GO:0044424 intracellular part Figure Label: GO:0044424 Species: Homo sapiens  Data Points: 12234  Description: "Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [GOC:jl] Available to: Everyone (Tier I)
	GS172060: HP:0001508 Failure to thrive Figure Label: HP:0001508 Species: Homo sapiens  Data Points: 283  Description: "Failure to thrive (FTT) refers to a child whose physical growth is substantially below the norm." [HPO:probinson] Available to: Everyone (Tier I)
	GS176840: HP:0001911 Abnormality of granulocytes Figure Label: HP:0001911 Species: Homo sapiens  Data Points: 114  Description: "An abnormality of `granulocytes` (CL:0000094)." [HPO:probinson] Available to: Everyone (Tier I)
	GS178909: GO:0017111 nucleoside-triphosphatase activity Figure Label: GO:0017111 Species: Mus musculus  Data Points: 602  Description: "Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate." [EC:3.6.1.15] Available to: Everyone (Tier I)
	GS135449: bone length and organs 5 (Bod5, Published QTL Chr 8) Figure Label: QTL-Bod5-Mouse-Chr 8 Species: Mus musculus  Data Points: 419  Description: QTL associated with bone length and organs 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (67215931) Available to: Everyone (Tier I)
	GS171453: HP:0003674 Onset Figure Label: HP:0003674 Species: Homo sapiens  Data Points: 570  Description: "The age and speed of the first appearance of the signs or symptoms of an illness." [HPO:probinson] Available to: Everyone (Tier I)
	GS209108: GO:0000166 nucleotide binding Figure Label: GO:0000166 Species: Homo sapiens  Data Points: 2432  Description: "Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose." [GOC:mah, ISBN:0198547684] Available to: Everyone (Tier I)
	GS174292: HP:0011968 Feeding difficulties Figure Label: HP:0011968 Species: Homo sapiens  Data Points: 237  Description: "Impaired ability to eat related to problems gathering food and getting ready to suck, chew, or swallow it." [ISCA:eriggs] Available to: Everyone (Tier I)
	GS86561: Table S2: Additional data file 2 - Lists of probe sets of genes with expression altered by acute and chronic morphine (ANOVA; FDR < 1%). ALL [DRG] provisional Figure Label: Chronic morphine - Morphine vs. Saline Species: Mus musculus  Data Points: 205  Description: Chronic morphine - Morphine vs. Saline DNA microarray Change in gene expression Mice received morphine thrice daily, 09:00 hours, 13:00 hours, and 17:00 hours, for 4 days using a dosing schedule of 10, 20, 40, and 40 mg / kg morphine on days 1, 2, 3, and 4, respectively. On the last day, a final morphine dose of 40 mg / kg was administered at 09:00 hours. The control group received injections of saline in the same time schedule. 4 hours after the last injection the animals were killed. ANOVA The results were obtained using fold change (>1.2) of gene expression level compared with the saline control group. (false discovery rate [FDR] < 1%) (NIF Table ID 134.5 [84.6]) Available to: Everyone (Tier I)
	GS175922: HP:0004341 Abnormality of the vitamin B12 metabolism Figure Label: HP:0004341 Species: Homo sapiens  Data Points: 10  Description: Abnormality of the vitamin B12 metabolism Available to: Everyone (Tier I)
	GS174763: HP:0010894 Abnormality of serine family amino acid metabolism Figure Label: HP:0010894 Species: Homo sapiens  Data Points: 17  Description: "An abnormality of a `serine family amino acid metabolic process` (GO:0009069)." [HPO:probinson] Available to: Everyone (Tier I)
	GS188652: GO:0001882 nucleoside binding Figure Label: GO:0001882 Species: Mus musculus  Data Points: 1745  Description: "Interacting selectively and non-covalently with a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose." [GOC:hjd] Available to: Everyone (Tier I)
	GS173155: HP:0005561 Abnormality of bone marrow cell morphology Figure Label: HP:0005561 Species: Homo sapiens  Data Points: 78  Description: "An anomaly of the form or number of cells in the `bone marrow` (FMA:9608)." [DDD:wouwehand, HPO:probinson] Available to: Everyone (Tier I)
	GS173242: HP:0001337 Tremor Figure Label: HP:0001337 Species: Homo sapiens  Data Points: 123  Description: "An unintentional, oscillating to-and-fro muscle movement." [HPO:probinson] Available to: Everyone (Tier I)
	GS135883: femur geometry 7 (Fmgty7, Published QTL Chr 8) Figure Label: QTL-Fmgty7-Mouse-Chr 8 Species: Mus musculus  Data Points: 573  Description: QTL associated with femur geometry 7. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (90920080) Available to: Everyone (Tier I)
	GS175601: HP:0002086 Abnormality of the respiratory system Figure Label: HP:0002086 Species: Homo sapiens  Data Points: 741  Description: "An abnormality of the `respiratory system` (FMA:7158), which include the airways, lungs, and the respiratory muscles." [HPO:probinson] Available to: Everyone (Tier I)
	GS176632: HP:0001903 Anemia Figure Label: HP:0001903 Species: Homo sapiens  Data Points: 223  Description: "A reduction in `erythrocytes` (CL:0000232) volume or hemoglobin concentration." [HPO:probinson] Available to: Everyone (Tier I)
	GS201799: GO:0032550 purine ribonucleoside binding Figure Label: GO:0032550 Species: Homo sapiens  Data Points: 1836  Description: "Interacting selectively and non-covalently with a purine ribonucleoside, a compound consisting of a purine base linked to ribose." [GOC:mah] Available to: Everyone (Tier I)
	GS201800: GO:0032553 ribonucleotide binding Figure Label: GO:0032553 Species: Homo sapiens  Data Points: 1877  Description: "Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] Available to: Everyone (Tier I)
	GS188651: GO:0001883 purine nucleoside binding Figure Label: GO:0001883 Species: Mus musculus  Data Points: 1736  Description: "Interacting selectively and non-covalently with a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose." [GOC:hjd] Available to: Everyone (Tier I)
	GS172360: HP:0004323 Abnormality of body weight Figure Label: HP:0004323 Species: Homo sapiens  Data Points: 534  Description: Abnormality of body weight Available to: Everyone (Tier I)
	GS175383: HP:0003210 Decreased methylmalonyl-CoA mutase activity Figure Label: HP:0003210 Species: Homo sapiens  Data Points: 4  Description: "An `abnormality of Krebs cycle metabolism` (HP:0000816) that is characterized by a `decreased rate` (PATO:0000911) of `methylmalonyl-CoA mutase activity` (GO:0004494)." [HPO:probinson] Available to: Everyone (Tier I)
	GS175619: HP:0002098 Respiratory distress Figure Label: HP:0002098 Species: Homo sapiens  Data Points: 24  Description: Respiratory distress Available to: Everyone (Tier I)
	GS199854: GO:0019001 guanyl nucleotide binding Figure Label: GO:0019001 Species: Homo sapiens  Data Points: 392  Description: "Interacting selectively and non-covalently with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS136572: radiation induced acute myeloid leukemia 4 (Raml4, Published QTL Chr 8) Figure Label: QTL-Raml4-Mouse-Chr 8 Species: Mus musculus  Data Points: 455  Description: QTL associated with radiation induced acute myeloid leukemia 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (73569352) Available to: Everyone (Tier I)
	GS210113: GO:0033014 tetrapyrrole biosynthetic process Figure Label: GO:0033014 Species: Homo sapiens  Data Points: 30  Description: "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [CHEBI:26932, GOC:mah] Available to: Everyone (Tier I)
	GS84205: chronic alcohol withdrawal severity (Published QTL, Chr 8) Figure Label: QTL for chronic alcohol withdrawal severity on Chr8 at D8Mit25 (65.54 Mbp , Build 37) Species: Mus musculus  Data Points: 421  Description: chronic alcohol withdrawal severity spans 40.54 - 90.54 Mbp (NCBI Build 37) on Chr8. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org). Available to: Everyone (Tier II)
	GS173093: HP:0004372 Reduced consciousness/confusion Figure Label: HP:0004372 Species: Homo sapiens  Data Points: 128  Description: Reduced consciousness/confusion Available to: Everyone (Tier I)
	GS175390: HP:0011007 Age of onset Figure Label: HP:0011007 Species: Homo sapiens  Data Points: 538  Description: "The age group in which disease manifestations appear." [HPO:probinson] Available to: Everyone (Tier I)
	GS186744: GO:0043226 organelle Figure Label: GO:0043226 Species: Mus musculus  Data Points: 9740  Description: "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS128597: Ethanol Induced Ataxia Chr#8 Figure Label: QTL-Ethanol Ataxia-Mouse-Chr8 Species: Mus musculus  Data Points: 704  Description: Ethanol Induced Ataxia Chr#8 rs3699406 (72486070) with right flanking marker rs6386110 (45897379) and left marker rs13479995(116236688). This was mapped in 300 + (b6x129)F2 mice. Available to: Everyone (Tier I)
	GS182835: GO:0005622 intracellular Figure Label: GO:0005622 Species: Mus musculus  Data Points: 11364  Description: "The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS202415: GO:0044710 single-organism metabolic process Figure Label: GO:0044710 Species: Homo sapiens  Data Points: 9213  Description: "A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism." [GOC:jl] Available to: Everyone (Tier I)
	GS207903: GO:0044281 small molecule metabolic process Figure Label: GO:0044281 Species: Homo sapiens  Data Points: 2511  Description: "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw] Available to: Everyone (Tier I)
	GS173012: HP:0004364 Abnormality of nitrogen compound homeostasis Figure Label: HP:0004364 Species: Homo sapiens  Data Points: 37  Description: "The presence of an abnormal concentration of `nitrogen compounds` (CHEBI:51143)." [HPO:gcarletti] Available to: Everyone (Tier I)
	GS135540: cerebellum weight 2 (Cbm2, Published QTL Chr 8) Figure Label: QTL-Cbm2-Mouse-Chr 8 Species: Mus musculus  Data Points: 542  Description: QTL associated with cerebellum weight 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (98042513) Available to: Everyone (Tier I)
	GS194133: GO:0005737 cytoplasm Figure Label: GO:0005737 Species: Homo sapiens  Data Points: 9128  Description: "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] Available to: Everyone (Tier I)
	GS194111: GO:0097159 organic cyclic compound binding Figure Label: GO:0097159 Species: Homo sapiens  Data Points: 5452  Description: "Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure." [CHEBI:33832, GOC:sjw, PMID:7583672] Available to: Everyone (Tier I)
	GS173015: HP:0003112 Abnormality of serum amino acid levels Figure Label: HP:0003112 Species: Homo sapiens  Data Points: 22  Description: "The presence of an abnormal decrease or increase of one or more amino acids in the blood circulation." [HPO:curators] Available to: Everyone (Tier I)
	GS189860: GO:0043167 ion binding Figure Label: GO:0043167 Species: Mus musculus  Data Points: 5225  Description: "Interacting selectively and non-covalently with ions, charged atoms or groups of atoms." [GOC:jl] Available to: Everyone (Tier I)
	GS175525: HP:0000004 Onset and clinical course Figure Label: HP:0000004 Species: Homo sapiens  Data Points: 827  Description: Onset and clinical course Available to: Everyone (Tier I)
	GS191129: GO:0016787 hydrolase activity Figure Label: GO:0016787 Species: Mus musculus  Data Points: 2190  Description: "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS206742: GO:0043167 ion binding Figure Label: GO:0043167 Species: Homo sapiens  Data Points: 5810  Description: "Interacting selectively and non-covalently with ions, charged atoms or groups of atoms." [GOC:jl] Available to: Everyone (Tier I)
	GS202828: GO:0016817 hydrolase activity, acting on acid anhydrides Figure Label: GO:0016817 Species: Homo sapiens  Data Points: 798  Description: "Catalysis of the hydrolysis of any acid anhydride." [GOC:jl] Available to: Everyone (Tier I)
	GS173534: HP:0001877 Abnormality of erythrocytes Figure Label: HP:0001877 Species: Homo sapiens  Data Points: 246  Description: "An abnormality of `erythrocytes` (CL:0000232) (red-blood cells)." [HPO:probinson] Available to: Everyone (Tier I)
	GS135259: autoimmune extremity vasculitis in MRL mice 1 (Aevm1, Published QTL Chr 8) Figure Label: QTL-Aevm1-Mouse-Chr 8 Species: Mus musculus  Data Points: 449  Description: QTL associated with autoimmune extremity vasculitis in MRL mice 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (73811716) Available to: Everyone (Tier I)
	GS175528: HP:0000007 Autosomal recessive inheritance Figure Label: HP:0000007 Species: Homo sapiens  Data Points: 1289  Description: "A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in homozygotes. In the context of medical genetics, autosomal recessive disorders manifest in homozygotes (with two copies of the mutant allele) or compound heterozygotes (whereby each copy of a gene has a distinct mutant allele)." [HPO:curators] Available to: Everyone (Tier I)
	GS135972: wound healing/regeneration 1 (Heal1, Published QTL Chr 8) Figure Label: QTL-Heal1-Mouse-Chr 8 Species: Mus musculus  Data Points: 586  Description: QTL associated with wound healing/regeneration 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (105240821) Available to: Everyone (Tier I)
	GS181473: GO:0005488 binding Figure Label: GO:0005488 Species: Mus musculus  Data Points: 10879  Description: "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." [GOC:ceb, GOC:mah, ISBN:0198506732] Available to: Everyone (Tier I)
	GS175526: HP:0000005 Mode of inheritance Figure Label: HP:0000005 Species: Homo sapiens  Data Points: 2121  Description: "The pattern in which a particular genetic trait or disorder is passed from one generation to the next." [HPO:probinson] Available to: Everyone (Tier I)
	GS175823: HP:0002093 Respiratory insufficiency Figure Label: HP:0002093 Species: Homo sapiens  Data Points: 266  Description: Respiratory insufficiency Available to: Everyone (Tier I)
	GS192512: GO:0003824 catalytic activity Figure Label: GO:0003824 Species: Mus musculus  Data Points: 5103  Description: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS180644: GO:0032549 ribonucleoside binding Figure Label: GO:0032549 Species: Mus musculus  Data Points: 1736  Description: "Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose." [GOC:mah] Available to: Everyone (Tier I)
	GS174137: HP:0002017 Nausea and vomiting Figure Label: HP:0002017 Species: Homo sapiens  Data Points: 130  Description: Nausea and vomiting Available to: Everyone (Tier I)
	GS200675: GO:0009236 cobalamin biosynthetic process Figure Label: GO:0009236 Species: Homo sapiens  Data Points: 3  Description: "The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom." [GOC:jl, ISBN:0198506732] Available to: Everyone (Tier I)
	GS171196: HP:0001944 Dehydration Figure Label: HP:0001944 Species: Homo sapiens  Data Points: 43  Description: Dehydration Available to: Everyone (Tier I)
	GS176170: HP:0001252 Muscular hypotonia Figure Label: HP:0001252 Species: Homo sapiens  Data Points: 534  Description: "Muscular hypotonia is an abnormally low muscle tone (the amount of tension or resistance to movement in a muscle), often involving reduced muscle strength. Hypotonia is characterized by a diminished resistance to passive stretching." [HPO:curators] Available to: Everyone (Tier I)
	GS207919: GO:0044283 small molecule biosynthetic process Figure Label: GO:0044283 Species: Homo sapiens  Data Points: 422  Description: "The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw] Available to: Everyone (Tier I)
	GS172672: HP:0004337 Abnormality of amino acid metabolism Figure Label: HP:0004337 Species: Homo sapiens  Data Points: 121  Description: "Abnormality of an `amino acid metabolic process` (GO:0006520)." [HPO:probinson] Available to: Everyone (Tier I)
	GS172415: HP:0002240 Hepatomegaly Figure Label: HP:0002240 Species: Homo sapiens  Data Points: 266  Description: "Abnormally `increased size` (PATO:0000586) of the `liver` (FMA:7197)." [HPO:probinson] Available to: Everyone (Tier I)
	GS197244: GO:0044237 cellular metabolic process Figure Label: GO:0044237 Species: Homo sapiens  Data Points: 8595  Description: "The chemical reactions and pathways by which individual cells transform chemical substances." [GOC:go_curators] Available to: Everyone (Tier I)
	GS198456: GO:0019438 aromatic compound biosynthetic process Figure Label: GO:0019438 Species: Homo sapiens  Data Points: 3626  Description: "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai] Available to: Everyone (Tier I)
	GS177409: GO:0005739 mitochondrion Figure Label: GO:0005739 Species: Mus musculus  Data Points: 1603  Description: "A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS173535: HP:0001874 Abnormality of neutrophils Figure Label: HP:0001874 Species: Homo sapiens  Data Points: 104  Description: "A `neutrophil` (CL:0000775) abnormality." [HPO:probinson] Available to: Everyone (Tier I)
	GS128577: Ethanol induced LORR Chr# 8 Figure Label: QTL-Ethanol LORR-Mouse-Chr8 Species: Mus musculus  Data Points: 836  Description: Ethanol induced LORR Chr# 8 rs3666140 (44049661) with right flanking marker rs3661760(24557766) and left marker rs13479995 (116236688). This was mapped in 300 + (b6x129)F2 mice. Available to: Everyone (Tier I)
	GS171305: HP:0012145 Abnormality of multiple cell lineages in the bone marrow Figure Label: HP:0012145 Species: Homo sapiens  Data Points: 55  Description: Abnormality of multiple cell lineages in the bone marrow Available to: Everyone (Tier I)
	GS175529: HP:0000001 All Figure Label: HP:0000001 Species: Homo sapiens  Data Points: 2374  Description: All Available to: Everyone (Tier I)
	GS87158: Table S2: Additional data file 2 - Lists of probe sets of genes with expression altered by acute and chronic morphine (ANOVA; FDR < 1%). DBA/2J [DRG] provisional Figure Label: Chronic morphine - Morphine vs. Saline Species: Mus musculus  Data Points: 149  Description: Chronic morphine - Morphine vs. Saline DNA microarray Change in gene expression Mice received morphine thrice daily, 09:00 hours, 13:00 hours, and 17:00 hours, for 4 days using a dosing schedule of 10, 20, 40, and 40 mg / kg morphine on days 1, 2, 3, and 4, respectively. On the last day, a final morphine dose of 40 mg / kg was administered at 09:00 hours. The control group received injections of saline in the same time schedule. 4 hours after the last injection the animals were killed. ANOVA; FDR < 1% The results were obtained using fold change (>1.2) of gene expression level compared with the saline control group. (NIF Table ID 136 [88]) Available to: Everyone (Tier I)
	GS194138: GO:0005739 mitochondrion Figure Label: GO:0005739 Species: Homo sapiens  Data Points: 1518  Description: "A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS184447: GO:0044424 intracellular part Figure Label: GO:0044424 Species: Mus musculus  Data Points: 11124  Description: "Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [GOC:jl] Available to: Everyone (Tier I)
	GS206737: GO:0043168 anion binding Figure Label: GO:0043168 Species: Homo sapiens  Data Points: 2392  Description: "Interacting selectively and non-covalently with anions, charged atoms or groups of atoms with a net negative charge." [GOC:jl] Available to: Everyone (Tier I)
	GS183592: GO:0032561 guanyl ribonucleotide binding Figure Label: GO:0032561 Species: Mus musculus  Data Points: 354  Description: "Interacting selectively and non-covalently with a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] Available to: Everyone (Tier I)
	GS186740: GO:0043229 intracellular organelle Figure Label: GO:0043229 Species: Mus musculus  Data Points: 9717  Description: "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS136300: mean platelet volume locus 2 (Mpvq2, Published QTL Chr 8) Figure Label: QTL-Mpvq2-Mouse-Chr 8 Species: Mus musculus  Data Points: 586  Description: QTL associated with mean platelet volume locus 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (105240821) Available to: Everyone (Tier I)
	GS175825: HP:0002094 Dyspnea Figure Label: HP:0002094 Species: Homo sapiens  Data Points: 46  Description: "Difficult or labored breathing." [HPO:probinson] Available to: Everyone (Tier I)
	GS173829: HP:0002912 Methylmalonic acidemia Figure Label: HP:0002912 Species: Homo sapiens  Data Points: 8  Description: "Increased concentration of `methylmalonic acid` (CHEBI:30860) in the blood." [HPO:probinson] Available to: Everyone (Tier I)
	GS208012: GO:0044464 cell part Figure Label: GO:0044464 Species: Homo sapiens  Data Points: 14644  Description: "Any constituent part of a cell, the basic structural and functional unit of all organisms." [GOC:jl] Available to: Everyone (Tier I)
	GS210212: GO:0005575 cellular_component Figure Label: GO:0005575 Species: Homo sapiens  Data Points: 17054  Description: "The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together." [GOC:go_curators] Available to: Everyone (Tier I)
	GS201239: GO:0046483 heterocycle metabolic process Figure Label: GO:0046483 Species: Homo sapiens  Data Points: 5369  Description: "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [CHEBI:5686, ISBN:0198506732] Available to: Everyone (Tier I)
	GS135466: blood pressure QTL 23 (Bpq23, Published QTL Chr 8) Figure Label: QTL-Bpq23-Mouse-Chr 8 Species: Mus musculus  Data Points: 445  Description: QTL associated with blood pressure QTL 23. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (77928397) Available to: Everyone (Tier I)
	GS172066: HP:0001987 Hyperammonemia Figure Label: HP:0001987 Species: Homo sapiens  Data Points: 29  Description: "An increased concentration of `ammonia` (CHEBI:16134) in the `blood` (FMA:9670)." [HPO:gcarletti] Available to: Everyone (Tier I)
	GS204243: GO:0006766 vitamin metabolic process Figure Label: GO:0006766 Species: Homo sapiens  Data Points: 124  Description: "The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems." [GOC:ai] Available to: Everyone (Tier I)
	GS135589: P. chabaudi malaria resistance QTL 2 (Char2, Published QTL Chr 8) Figure Label: QTL-Char2-Mouse-Chr 8 Species: Mus musculus  Data Points: 519  Description: QTL associated with P. chabaudi malaria resistance QTL 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (98606078) Available to: Everyone (Tier I)
	GS179580: GO:0036094 small molecule binding Figure Label: GO:0036094 Species: Mus musculus  Data Points: 2439  Description: "Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:pm] Available to: Everyone (Tier I)
	GS194038: GO:1901362 organic cyclic compound biosynthetic process Figure Label: GO:1901362 Species: Homo sapiens  Data Points: 3737  Description: "The chemical reactions and pathways resulting in the formation of organic cyclic compound." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS136672: skull morphology 11 (Skull11, Published QTL Chr 8) Figure Label: QTL-Skull11-Mouse-Chr 8 Species: Mus musculus  Data Points: 419  Description: QTL associated with skull morphology 11. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (67215931) Available to: Everyone (Tier I)
	GS172403: HP:0011873 Abnormal platelet count Figure Label: HP:0011873 Species: Homo sapiens  Data Points: 124  Description: "Abnormal number of platelets per volume of blood. In a healthy adult, a normal platelet count is between 150,000 and 450,000 per microliter of blood." [DDD:kfreson] Available to: Everyone (Tier I)
	GS136032: induction of brown adipocytes 3 (Iba3, Published QTL Chr 8) Figure Label: QTL-Iba3-Mouse-Chr 8 Species: Mus musculus  Data Points: 417  Description: QTL associated with induction of brown adipocytes 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (63773677) Available to: Everyone (Tier I)
	GS176801: HP:0001263 Global developmental delay Figure Label: HP:0001263 Species: Homo sapiens  Data Points: 442  Description: "A delay in the achievement of motor or mental milestones in the domains of development of a child, including motor skills, speech and language, cognitive skills, and social and emotional skills. This term should only be used to describe children younger than five years of age." [DDD:hvfirth, HPO:sdoelken] Available to: Everyone (Tier I)
	GS171040: HP:0002157 Azotemia Figure Label: HP:0002157 Species: Homo sapiens  Data Points: 36  Description: "An increased concentration of `nitrogen compounds` (CHEBI:51143) in the `blood` (FMA:9670)." [HPO:gcarletti] Available to: Everyone (Tier I)
	GS174385: HP:0002088 Abnormality of the lung Figure Label: HP:0002088 Species: Homo sapiens  Data Points: 545  Description: "An abnormality of the `lung` (FMA:7195)." [HPO:probinson] Available to: Everyone (Tier I)
	GS174500: HP:0000707 Abnormality of the nervous system Figure Label: HP:0000707 Species: Homo sapiens  Data Points: 1569  Description: "An abnormality of the `nervous system` (FMA:7157)." [HPO:probinson] Available to: Everyone (Tier I)
	GS171998: HP:0001939 Abnormality of metabolism/homeostasis Figure Label: HP:0001939 Species: Homo sapiens  Data Points: 1228  Description: Abnormality of metabolism/homeostasis Available to: Everyone (Tier I)
	GS206779: GO:0009110 vitamin biosynthetic process Figure Label: GO:0009110 Species: Homo sapiens  Data Points: 26  Description: "The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:go_curators, ISBN:0198506732] Available to: Everyone (Tier I)
	GS182834: GO:0005623 cell Figure Label: GO:0005623 Species: Mus musculus  Data Points: 13187  Description: "The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:go_curators] Available to: Everyone (Tier I)
	GS172745: HP:0010995 Abnormality of dicarboxylic acid metabolism Figure Label: HP:0010995 Species: Homo sapiens  Data Points: 24  Description: "An abnormality of `dicarboxylic acid` (CHEBI:35692) metabolism." [HPO:probinson] Available to: Everyone (Tier I)
	GS205511: GO:0001882 nucleoside binding Figure Label: GO:0001882 Species: Homo sapiens  Data Points: 1850  Description: "Interacting selectively and non-covalently with a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose." [GOC:hjd] Available to: Everyone (Tier I)
	GS175918: HP:0002919 Ketonuria Figure Label: HP:0002919 Species: Homo sapiens  Data Points: 6  Description: "High levels of ketone bodies in the urine." [HPO:probinson] Available to: Everyone (Tier I)
	GS174914: HP:0003011 Abnormality of the musculature Figure Label: HP:0003011 Species: Homo sapiens  Data Points: 1006  Description: "Abnormality originating in one or more muscles, i.e., of the `set of muscles of body` (FMA:72954)." [HPO:probinson] Available to: Everyone (Tier I)
	GS199635: GO:0005622 intracellular Figure Label: GO:0005622 Species: Homo sapiens  Data Points: 12561  Description: "The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS176038: HP:0002795 Functional respiratory abnormality Figure Label: HP:0002795 Species: Homo sapiens  Data Points: 378  Description: Functional respiratory abnormality Available to: Everyone (Tier I)
	GS196943: GO:0008152 metabolic process Figure Label: GO:0008152 Species: Homo sapiens  Data Points: 9471  Description: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684] Available to: Everyone (Tier I)
	GS173537: HP:0001872 Abnormality of thrombocytes Figure Label: HP:0001872 Species: Homo sapiens  Data Points: 148  Description: "An abnormality of `platelets` (CL:0000233)." [HPO:probinson] Available to: Everyone (Tier I)
	GS87381: Table S1: Additional data file 1 is a table listing the results of two-way ANOVA (FDR < 1%). (Whole Table) [DRG] provisional Figure Label: Morphine: Chronic, Acute and Withdrawal - Morphine vs. Control Species: Mus musculus  Data Points: 612  Description: Morphine: Chronic, Acute and Withdrawal - Morphine vs. Control DNA microarray Change in gene expression Control and acute morphine groups received injections of saline in the same time schedule as the chronic group received morphine (thrice daily, 09:00 hours, 13:00 hours, and 17:00 hours, for 4 days using a dosing schedule of 10, 20, 40, and 40 mg / kg morphine on days 1, 2, 3, and 4, respectively). On day 5, acutely treated animals were injected with a single dose of morphine, 20 mg / kg at 09:00 hours, chronic group received 40 mg / kg, and control group received saline. Mice were killed by d Two-way analysis of variance (ANOVA). Morphine treatment altered the expression of 618 transcripts covered by 661 probe sets (false discovery rate [FDR] < 1%, rank > 3). (NIF Method ID 84.2) Available to: Everyone (Tier I)
	GS196941: GO:0008150 biological_process Figure Label: GO:0008150 Species: Homo sapiens  Data Points: 14623  Description: "Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end." [GOC:go_curators, GOC:isa_complete] Available to: Everyone (Tier I)
	GS199634: GO:0005623 cell Figure Label: GO:0005623 Species: Homo sapiens  Data Points: 14645  Description: "The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:go_curators] Available to: Everyone (Tier I)
	GS86497: Table S2: Additional data file 2 - Lists of probe sets of genes with expression altered by acute and chronic morphine (ANOVA; FDR < 1%). C57BL/6J [DRG] provisional Figure Label: Chronic morphine - Morphine vs. Saline Species: Mus musculus  Data Points: 361  Description: Chronic morphine - Morphine vs. Saline DNA microarray Change in gene expression Mice received morphine thrice daily, 09:00 hours, 13:00 hours, and 17:00 hours, for 4 days using a dosing schedule of 10, 20, 40, and 40 mg / kg morphine on days 1, 2, 3, and 4, respectively. On the last day, a final morphine dose of 40 mg / kg was administered at 09:00 hours. The control group received injections of saline in the same time schedule. 4 hours after the last injection the animals were killed. ANOVA; FDR < 1% The results were obtained using fold change (>1.2) of gene expression level compared with the saline control group. (NIF Table ID 135 [86]) Available to: Everyone (Tier I)
	GS173647: HP:0012072 Aciduria Figure Label: HP:0012072 Species: Homo sapiens  Data Points: 113  Description: "Ecretion of urine with an acid pH." [HPO:probinson] Available to: Everyone (Tier I)
	GS174133: HP:0002013 Vomiting Figure Label: HP:0002013 Species: Homo sapiens  Data Points: 105  Description: "Forceful ejection of the contents of the stomach through the mouth by means of a series of involuntary spasmic contractions." [HPO:probinson] Available to: Everyone (Tier I)
	GS136390: autoimmune orchitis resistance 6 (Orch6, Published QTL Chr 8) Figure Label: QTL-Orch6-Mouse-Chr 8 Species: Mus musculus  Data Points: 444  Description: QTL associated with autoimmune orchitis resistance 6. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (80310749) Available to: Everyone (Tier I)
	GS175827: HP:0010895 Abnormality of glycine metabolism Figure Label: HP:0010895 Species: Homo sapiens  Data Points: 17  Description: "An abnormality of a `glycine metabolic process` (GO:0006544)." [HPO:gcarletti] Available to: Everyone (Tier I)
	GS135252: adiposity 4 (Adip4, Published QTL Chr 8) Figure Label: QTL-Adip4-Mouse-Chr 8 Species: Mus musculus  Data Points: 419  Description: QTL associated with adiposity 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (67115827) Available to: Everyone (Tier I)
	GS209564: GO:0043231 intracellular membrane-bounded organelle Figure Label: GO:0043231 Species: Homo sapiens  Data Points: 9574  Description: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS183053: GO:0019001 guanyl nucleotide binding Figure Label: GO:0019001 Species: Mus musculus  Data Points: 354  Description: "Interacting selectively and non-covalently with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS171274: HP:0100543 Cognitive impairment Figure Label: HP:0100543 Species: Homo sapiens  Data Points: 1060  Description: "Abnormality in the process of thought including the ability to process information." [HPO:sdoelken] Available to: Everyone (Tier I)
	GS175805: HP:0003271 Visceromegaly Figure Label: HP:0003271 Species: Homo sapiens  Data Points: 310  Description: "Abnormal `increased size` (PATO:0000586) of the `viscera of the abdomen` (FMA:259123)." [HPO:probinson] Available to: Everyone (Tier I)
	GS129101: bone mineral density 39 (Bmd39 Published QTL Chr 8) Figure Label: QTL-Bmd39-Mouse-Chr 8 Species: Mus musculus  Data Points: 747  Description: QTL associated with bone mineral density 39. The confidence interval is Chr8:33127016-119762600 bp,+strand Available to: Everyone (Tier I)
	GS204837: GO:0042364 water-soluble vitamin biosynthetic process Figure Label: GO:0042364 Species: Homo sapiens  Data Points: 10  Description: "The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water." [GOC:jl] Available to: Everyone (Tier I)
	GS205047: GO:0006807 nitrogen compound metabolic process Figure Label: GO:0006807 Species: Homo sapiens  Data Points: 5962  Description: "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium." [CHEBI:51143, GOC:go_curators, GOC:jl, ISBN:0198506732] Available to: Everyone (Tier I)
	GS135268: alopecia areata 3 (Alaa3, Published QTL Chr 8) Figure Label: QTL-Alaa3-Mouse-Chr 8 Species: Mus musculus  Data Points: 414  Description: QTL associated with alopecia areata 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (68316838) Available to: Everyone (Tier I)
	GS135780: exercise endurance QTL 2 (Eeq2, Published QTL Chr 8) Figure Label: QTL-Eeq2-Mouse-Chr 8 Species: Mus musculus  Data Points: 444  Description: QTL associated with exercise endurance QTL 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (74716979) Available to: Everyone (Tier I)
	GS176186: HP:0000079 Abnormality of the urinary system Figure Label: HP:0000079 Species: Homo sapiens  Data Points: 737  Description: "An abnormality of the `urinary system` (FMA:7159)." [HPO:probinson] Available to: Everyone (Tier I)
	GS175172: HP:0004354 Abnormality of carboxylic acid metabolism Figure Label: HP:0004354 Species: Homo sapiens  Data Points: 134  Description: "An abnormality of the metabolism of a `carboxylic acid` (CHEBI:33575)." [HPO:gcarletti] Available to: Everyone (Tier I)
	GS127240: Acetaminophen interacting genes (MeSH:D000082) in CTD Figure Label: D000082 [CTD] Species: Homo sapiens  Data Points: 5725  Description: Genes that interact with the MeSH term 'Acetaminophen' (D000082). Incorporates data from 193 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene. Available to: Everyone (Tier I)
	GS176168: HP:0001254 Lethargy Figure Label: HP:0001254 Species: Homo sapiens  Data Points: 71  Description: "A state of disinterestedness, listlessness, and indifference, resulting in difficulty performing simple tasks or concentrating." [HPO:probinson] Available to: Everyone (Tier I)
	GS185881: GO:0035639 purine ribonucleoside triphosphate binding Figure Label: GO:0035639 Species: Mus musculus  Data Points: 1724  Description: "Interacting selectively and non-covalently with a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar." [CHEBI:26398, GOC:BHF, GOC:ebc, ISBN:0198506732] Available to: Everyone (Tier I)
	GS185991: GO:0016817 hydrolase activity, acting on acid anhydrides Figure Label: GO:0016817 Species: Mus musculus  Data Points: 643  Description: "Catalysis of the hydrolysis of any acid anhydride." [GOC:jl] Available to: Everyone (Tier I)
	GS171789: HP:0001392 Abnormality of the liver Figure Label: HP:0001392 Species: Homo sapiens  Data Points: 487  Description: "An abnormality of the `liver` (FMA:7197)." [HPO:probinson] Available to: Everyone (Tier I)
	GS205180: GO:0005525 GTP binding Figure Label: GO:0005525 Species: Homo sapiens  Data Points: 379  Description: "Interacting selectively and non-covalently with GTP, guanosine triphosphate." [GOC:ai] Available to: Everyone (Tier I)
	GS173028: HP:0004360 Abnormality of acid-base homeostasis Figure Label: HP:0004360 Species: Homo sapiens  Data Points: 182  Description: "An abnormality of the balance or maintenance of the balance of acids and bases in bodily fluids, resulting in an abnormal pH." [HPO:probinson] Available to: Everyone (Tier I)
	GS202716: GO:0035639 purine ribonucleoside triphosphate binding Figure Label: GO:0035639 Species: Homo sapiens  Data Points: 1827  Description: "Interacting selectively and non-covalently with a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar." [CHEBI:26398, GOC:BHF, GOC:ebc, ISBN:0198506732] Available to: Everyone (Tier I)
	GS203594: GO:0043226 organelle Figure Label: GO:0043226 Species: Homo sapiens  Data Points: 10639  Description: "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS195665: GO:0017111 nucleoside-triphosphatase activity Figure Label: GO:0017111 Species: Homo sapiens  Data Points: 758  Description: "Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate." [EC:3.6.1.15] Available to: Everyone (Tier I)
	GS173130: HP:0001875 Neutropenia Figure Label: HP:0001875 Species: Homo sapiens  Data Points: 43  Description: "An abnormally low number of `neutrophils` (CL:0000775) in the peripheral `blood` (FMA:9670)." [HPO:probinson] Available to: Everyone (Tier I)
	GS136755: susceptibility to Salmonella typhimurium antigens 6 (Ssta6, Published QTL Chr 8) Figure Label: QTL-Ssta6-Mouse-Chr 8 Species: Mus musculus  Data Points: 501  Description: QTL associated with susceptibility to Salmonella typhimurium antigens 6. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (83463446) Available to: Everyone (Tier I)
	GS200446: GO:0017076 purine nucleotide binding Figure Label: GO:0017076 Species: Homo sapiens  Data Points: 1869  Description: "Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate." [GOC:ai] Available to: Everyone (Tier I)
	GS210002: GO:0044444 cytoplasmic part Figure Label: GO:0044444 Species: Homo sapiens  Data Points: 6769  Description: "Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GOC:jl] Available to: Everyone (Tier I)
	GS209009: GO:1901576 organic substance biosynthetic process Figure Label: GO:1901576 Species: Homo sapiens  Data Points: 5152  Description: "The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie] Available to: Everyone (Tier I)
	GS184983: GO:0032550 purine ribonucleoside binding Figure Label: GO:0032550 Species: Mus musculus  Data Points: 1733  Description: "Interacting selectively and non-covalently with a purine ribonucleoside, a compound consisting of a purine base linked to ribose." [GOC:mah] Available to: Everyone (Tier I)
	GS174331: HP:0002715 Abnormality of the immune system Figure Label: HP:0002715 Species: Homo sapiens  Data Points: 680  Description: "An abnormality of the `immune system` (FMA:9825)." [HPO:probinson] Available to: Everyone (Tier I)
	GS192174: GO:0000166 nucleotide binding Figure Label: GO:0000166 Species: Mus musculus  Data Points: 2263  Description: "Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose." [GOC:mah, ISBN:0198547684] Available to: Everyone (Tier I)
	GS203593: GO:0043227 membrane-bounded organelle Figure Label: GO:0043227 Species: Homo sapiens  Data Points: 9585  Description: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS172158: HP:0100508 Abnormality of vitamin metabolism Figure Label: HP:0100508 Species: Homo sapiens  Data Points: 12  Description: Abnormality of vitamin metabolism Available to: Everyone (Tier I)
	GS174131: HP:0002011 Abnormality of the central nervous system Figure Label: HP:0002011 Species: Homo sapiens  Data Points: 1495  Description: "An abnormality of the `central nervous system` (FMA:55675)." [HPO:curators] Available to: Everyone (Tier I)
	GS194087: GO:0003674 molecular_function Figure Label: GO:0003674 Species: Homo sapiens  Data Points: 15286  Description: "Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions." [GOC:go_curators] Available to: Everyone (Tier I)
	GS173026: HP:0000816 Abnormality of Krebs cycle metabolism Figure Label: HP:0000816 Species: Homo sapiens  Data Points: 6  Description: "An abnormality of the `tricarboxylic acid cycle` (GO:0006099)." [HPO:probinson] Available to: Everyone (Tier I)
	GS177356: GO:0003674 molecular_function Figure Label: GO:0003674 Species: Mus musculus  Data Points: 23365  Description: "Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions." [GOC:go_curators] Available to: Everyone (Tier I)
	GS203590: GO:0043229 intracellular organelle Figure Label: GO:0043229 Species: Homo sapiens  Data Points: 10624  Description: "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS173533: HP:0001876 Pancytopenia Figure Label: HP:0001876 Species: Homo sapiens  Data Points: 33  Description: "An abnormal reduction in numbers of all blood cell types (red blood cells, white blood cells, and platelets)." [HPO:probinson] Available to: Everyone (Tier I)
	GS177309: GO:1901363 heterocyclic compound binding Figure Label: GO:1901363 Species: Mus musculus  Data Points: 4588  Description: "Interacting selectively and non-covalently with heterocyclic compound." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS176610: HP:0003593 Infantile onset Figure Label: HP:0003593 Species: Homo sapiens  Data Points: 255  Description: "Onset of signs or symptoms of disease between 28 days to one year of life." [HPO:probinson] Available to: Everyone (Tier I)
	GS136533: preaxial shift (Prxsh, Published QTL Chr 8) Figure Label: QTL-Prxsh-Mouse-Chr 8 Species: Mus musculus  Data Points: 519  Description: QTL associated with preaxial shift. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (84433952) Available to: Everyone (Tier I)
	GS175119: HP:0001881 Abnormality of leukocytes Figure Label: HP:0001881 Species: Homo sapiens  Data Points: 285  Description: "An abnormality of `leukocytes` (CL:0000738)." [HPO:probinson] Available to: Everyone (Tier I)
	GS171201: HP:0001941 Acidosis Figure Label: HP:0001941 Species: Homo sapiens  Data Points: 167  Description: "Abnormal acid accumulation or depletion of base." [HPO:probinson] Available to: Everyone (Tier I)
	GS176175: HP:0001259 Coma Figure Label: HP:0001259 Species: Homo sapiens  Data Points: 59  Description: "Complete absence of wakefulness and content of conscience, which manifests itself as a lack of response to any kind of external stimuli." [HPO:probinson] Available to: Everyone (Tier I)
	GS136313: non-HDL QTL 1 (Nhdlq1, Published QTL Chr 8) Figure Label: QTL-Nhdlq1-Mouse-Chr 8 Species: Mus musculus  Data Points: 574  Description: QTL associated with non-HDL QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (95209247) Available to: Everyone (Tier I)
	GS171832: HP:0000118 Phenotypic abnormality Figure Label: HP:0000118 Species: Homo sapiens  Data Points: 2339  Description: "A phenotypic abnormality." [HPO:probinson] Available to: Everyone (Tier I)
	GS203886: GO:1901265 nucleoside phosphate binding Figure Label: GO:1901265 Species: Homo sapiens  Data Points: 2433  Description: "Interacting selectively and non-covalently with nucleoside phosphate." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS135989: Hfe modifier 2 (Hfem2, Published QTL Chr 8) Figure Label: QTL-Hfem2-Mouse-Chr 8 Species: Mus musculus  Data Points: 586  Description: QTL associated with Hfe modifier 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (105240821) Available to: Everyone (Tier I)
	GS204631: GO:1901566 organonitrogen compound biosynthetic process Figure Label: GO:1901566 Species: Homo sapiens  Data Points: 645  Description: "The chemical reactions and pathways resulting in the formation of organonitrogen compound." [GOC:pr, GOC:TermGenie] Available to: Everyone (Tier I)
	GS177382: GO:0097159 organic cyclic compound binding Figure Label: GO:0097159 Species: Mus musculus  Data Points: 4637  Description: "Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure." [CHEBI:33832, GOC:sjw, PMID:7583672] Available to: Everyone (Tier I)
	GS172687: HP:0012120 Methylmalonic aciduria Figure Label: HP:0012120 Species: Homo sapiens  Data Points: 8  Description: "Increased concentration of `methylmalonic acid` (CHEBI:30860) in the urine." [HPO:probinson] Available to: Everyone (Tier I)
	GS84206: METH responses for body temperature (Published QTL, Chr 8) Figure Label: QTL for METH responses for body temperature on Chr8 at D8Ncvs43 (95.66 Mbp , Build 37) Species: Mus musculus  Data Points: 573  Description: METH responses for body temperature spans 70.66 - 120.66 Mbp (NCBI Build 37) on Chr8. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org). Available to: Everyone (Tier II)
	GS173577: HP:0011991 Abnormal neutrophil cell number Figure Label: HP:0011991 Species: Homo sapiens  Data Points: 43  Description: "A deviation from the normal range of neutrophil cell counts in the circulation." [HPO:probinson] Available to: Everyone (Tier I)
	GS175537: HP:0011277 Abnormality of the urinary system physiology Figure Label: HP:0011277 Species: Homo sapiens  Data Points: 391  Description: Abnormality of the urinary system physiology Available to: Everyone (Tier I)
	GS136068: immune response to AAV2 QTL 2 (Imraq2, Published QTL Chr 8) Figure Label: QTL-Imraq2-Mouse-Chr 8 Species: Mus musculus  Data Points: 573  Description: QTL associated with immune response to AAV2 QTL 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (89829274) Available to: Everyone (Tier I)
	GS184978: GO:0032555 purine ribonucleotide binding Figure Label: GO:0032555 Species: Mus musculus  Data Points: 1759  Description: "Interacting selectively and non-covalently with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] Available to: Everyone (Tier I)
	GS87045: Table S2: Additional data file 2 - Lists of probe sets of genes with expression altered by acute and chronic morphine (ANOVA; FDR < 1%). SWR/J [DRG] provisional Figure Label: Chronic morphine - Morphine vs. Saline Species: Mus musculus  Data Points: 195  Description: Chronic morphine - Morphine vs. Saline DNA microarray Change in gene expression Mice received morphine thrice daily, 09:00 hours, 13:00 hours, and 17:00 hours, for 4 days using a dosing schedule of 10, 20, 40, and 40 mg / kg morphine on days 1, 2, 3, and 4, respectively. On the last day, a final morphine dose of 40 mg / kg was administered at 09:00 hours. The control group received injections of saline in the same time schedule. 4 hours after the last injection the animals were killed. ANOVA; FDR < 1% The results were obtained using fold change (>1.2) of gene expression level compared with the saline control group. (NIF Table ID 137 [90]) Available to: Everyone (Tier I)
	GS135913: glomerulsclerosis index 1 (Gsi1, Published QTL Chr 8) Figure Label: QTL-Gsi1-Mouse-Chr 8 Species: Mus musculus  Data Points: 419  Description: QTL associated with glomerulsclerosis index 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (67115827) Available to: Everyone (Tier I)
	GS171198: HP:0001942 Metabolic acidosis Figure Label: HP:0001942 Species: Homo sapiens  Data Points: 50  Description: "Acid accumulation or depletion of base in the body due to buildup of metabolic acids." [HPO:probinson] Available to: Everyone (Tier I)
	GS135613: circulating hormone level QTL 5 (Chlq5, Published QTL Chr 8) Figure Label: QTL-Chlq5-Mouse-Chr 8 Species: Mus musculus  Data Points: 573  Description: QTL associated with circulating hormone level QTL 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (90920080) Available to: Everyone (Tier I)
	GS172438: HP:0002154 Hyperglycinemia Figure Label: HP:0002154 Species: Homo sapiens  Data Points: 9  Description: "An elevated concentration of `glycine` (CHEBI:15428) in the `blood` (FMA:9670)." [HPO:gcarletti, pmid:16902722, pmid:4696900] Available to: Everyone (Tier I)
	GS86517: Table S2: Additional data file 2 - Lists of probe sets of genes with expression altered by acute and chronic morphine (ANOVA; FDR < 1%). 129P3/J [DRG] provisional Figure Label: Chronic morphine - Morphine vs. Saline Species: Mus musculus  Data Points: 159  Description: Chronic morphine - Morphine vs. Saline DNA microarray Change in gene expression Mice received morphine thrice daily, 09:00 hours, 13:00 hours, and 17:00 hours, for 4 days using a dosing schedule of 10, 20, 40, and 40 mg / kg morphine on days 1, 2, 3, and 4, respectively. On the last day, a final morphine dose of 40 mg / kg was administered at 09:00 hours. The control group received injections of saline in the same time schedule. 4 hours after the last injection the animals were killed. ANOVA; FDR < 1% The results were obtained using fold change (>1.2) of gene expression level compared with the saline control group. (NIF Table ID 138 [92]) Available to: Everyone (Tier I)
	GS176171: HP:0001250 Seizures Figure Label: HP:0001250 Species: Homo sapiens  Data Points: 616  Description: "Seizures are an intermittent `abnormality of the central nervous system` (FMA:HP:0002011) due to a sudden, excessive, disorderly discharge of cerebral neurons and characterized clinically by some combination of disturbance of sensation, loss of consciousness, impairment of psychic function, or convulsive movements. The term epilepsy is used to describe chronic, recurrent seizures." [HPO:probinson] Available to: Everyone (Tier I)
	GS195214: GO:0009987 cellular process Figure Label: GO:0009987 Species: Homo sapiens  Data Points: 12850  Description: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete] Available to: Everyone (Tier I)
	GS188323: GO:0005525 GTP binding Figure Label: GO:0005525 Species: Mus musculus  Data Points: 337  Description: "Interacting selectively and non-covalently with GTP, guanosine triphosphate." [GOC:ai] Available to: Everyone (Tier I)
	GS193193: GO:0016462 pyrophosphatase activity Figure Label: GO:0016462 Species: Mus musculus  Data Points: 638  Description: "Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments." [EC:3.6.1.-, GOC:curators] Available to: Everyone (Tier I)
	GS175380: HP:0003215 Dicarboxylic aciduria Figure Label: HP:0003215 Species: Homo sapiens  Data Points: 22  Description: "An increased concentration of `dicarboxylic acid` (CHEBI:35692) in the `urine` (FMA:12274)." [HPO:gcarletti] Available to: Everyone (Tier I)
	GS175673: HP:0100022 Abnormality of movement Figure Label: HP:0100022 Species: Homo sapiens  Data Points: 543  Description: "An abnormality of movement with a neurological basis characterized by changes in coordination and speed of voluntary movements." [HPO:probinson] Available to: Everyone (Tier I)
	GS201794: GO:0032555 purine ribonucleotide binding Figure Label: GO:0032555 Species: Homo sapiens  Data Points: 1862  Description: "Interacting selectively and non-covalently with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] Available to: Everyone (Tier I)
	GS203642: GO:0006725 cellular aromatic compound metabolic process Figure Label: GO:0006725 Species: Homo sapiens  Data Points: 5379  Description: "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells." [GOC:ai, ISBN:0198506732] Available to: Everyone (Tier I)
	GS210114: GO:0033013 tetrapyrrole metabolic process Figure Label: GO:0033013 Species: Homo sapiens  Data Points: 46  Description: "The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [CHEBI:26932, GOC:mah] Available to: Everyone (Tier I)
	GS174335: HP:0001871 Abnormality of blood and blood-forming tissues Figure Label: HP:0001871 Species: Homo sapiens  Data Points: 626  Description: "An abnormality of the `hematopoietic system` (FMA:9667)." [HPO:probinson] Available to: Everyone (Tier I)
	GS207923: GO:0034641 cellular nitrogen compound metabolic process Figure Label: GO:0034641 Species: Homo sapiens  Data Points: 5601  Description: "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." [GOC:mah] Available to: Everyone (Tier I)
	GS187023: GO:1901265 nucleoside phosphate binding Figure Label: GO:1901265 Species: Mus musculus  Data Points: 2263  Description: "Interacting selectively and non-covalently with nucleoside phosphate." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS198263: GO:0005488 binding Figure Label: GO:0005488 Species: Homo sapiens  Data Points: 11955  Description: "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." [GOC:ceb, GOC:mah, ISBN:0198506732] Available to: Everyone (Tier I)
	GS136920: vertebral morphology and mechanical traits 8 (Vmmt8, Published QTL Chr 8) Figure Label: QTL-Vmmt8-Mouse-Chr 8 Species: Mus musculus  Data Points: 573  Description: QTL associated with vertebral morphology and mechanical traits 8. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (90920080) Available to: Everyone (Tier I)
	GS194040: GO:1901360 organic cyclic compound metabolic process Figure Label: GO:1901360 Species: Homo sapiens  Data Points: 5558  Description: "The chemical reactions and pathways involving organic cyclic compound." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS176040: HP:0011032 Abnormality of fluid regulation Figure Label: HP:0011032 Species: Homo sapiens  Data Points: 213  Description: "An abnormality of the `regulation of body fluids` (GO:0050878)." [HPO:probinson] Available to: Everyone (Tier I)
	GS135397: body growth early QTL 7 (Bgeq7, Published QTL Chr 8) Figure Label: QTL-Bgeq7-Mouse-Chr 8 Species: Mus musculus  Data Points: 419  Description: QTL associated with body growth early QTL 7. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (67215931) Available to: Everyone (Tier I)
	GS208037: GO:0016787 hydrolase activity Figure Label: GO:0016787 Species: Homo sapiens  Data Points: 2353  Description: "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS172365: HP:0003110 Abnormality of urine homeostasis Figure Label: HP:0003110 Species: Homo sapiens  Data Points: 268  Description: "An abnormality of the composition of urine or the levels of its components." [HPO:probinson] Available to: Everyone (Tier I)
	GS136512: prion incubation time 3 (Pitm3, Published QTL Chr 8) Figure Label: QTL-Pitm3-Mouse-Chr 8 Species: Mus musculus  Data Points: 568  Description: QTL associated with prion incubation time 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (92726394) Available to: Everyone (Tier I)
	GS135717: despair 1 (Desp1, Published QTL Chr 8) Figure Label: QTL-Desp1-Mouse-Chr 8 Species: Mus musculus  Data Points: 589  Description: QTL associated with despair 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (104283476) Available to: Everyone (Tier I)
	GS210357: GO:0044249 cellular biosynthetic process Figure Label: GO:0044249 Species: Homo sapiens  Data Points: 5047  Description: "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:jl] Available to: Everyone (Tier I)
	GS172362: HP:0004325 Decreased body weight Figure Label: HP:0004325 Species: Homo sapiens  Data Points: 394  Description: Decreased body weight Available to: Everyone (Tier I)
	GS173538: HP:0001873 Thrombocytopenia Figure Label: HP:0001873 Species: Homo sapiens  Data Points: 121  Description: "A reduction in the number of circulating `thrombocytes` (CL:0000762)." [HPO:probinson] Available to: Everyone (Tier I)
	GS135844: femoral cross-sectional area 2 (Fcsa2, Published QTL Chr 8) Figure Label: QTL-Fcsa2-Mouse-Chr 8 Species: Mus musculus  Data Points: 573  Description: QTL associated with femoral cross-sectional area 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (89829274) Available to: Everyone (Tier I)
	GS171637: HP:0008872 Feeding difficulties in infancy Figure Label: HP:0008872 Species: Homo sapiens  Data Points: 199  Description: "Impaired feeding performance of an infant as manifested by difficulties such as weak and ineffective sucking, brief bursts of sucking, and falling asleep during sucking. There may be difficulties with chewing or maintaining attention." [HPO:probinson] Available to: Everyone (Tier I)
	GS206953: GO:0018130 heterocycle biosynthetic process Figure Label: GO:0018130 Species: Homo sapiens  Data Points: 3640  Description: "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198547684] Available to: Everyone (Tier I)
	GS136369: obesity QTL 16 (Obq16, Published QTL Chr 8) Figure Label: QTL-Obq16-Mouse-Chr 8 Species: Mus musculus  Data Points: 574  Description: QTL associated with obesity QTL 16. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (95209247) Available to: Everyone (Tier I)
	GS174453: HP:0001438 Abnormality of the abdomen Figure Label: HP:0001438 Species: Homo sapiens  Data Points: 1051  Description: "Abnormality of the `abdomen` (FMA:9577) ('belly'), that is, the part of the body between the pelvis and the thorax." [HPO:probinson] Available to: Everyone (Tier I)
	GS194499: GO:0044271 cellular nitrogen compound biosynthetic process Figure Label: GO:0044271 Species: Homo sapiens  Data Points: 3721  Description: "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732] Available to: Everyone (Tier I)
	GS180164: GO:0008150 biological_process Figure Label: GO:0008150 Species: Mus musculus  Data Points: 23855  Description: "Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end." [GOC:go_curators, GOC:isa_complete] Available to: Everyone (Tier I)
	GS171833: HP:0000119 Abnormality of the genitourinary system Figure Label: HP:0000119 Species: Homo sapiens  Data Points: 990  Description: "The presence of any abnormality of the `genitourinary system` (FMA:280610)." [HPO:curators] Available to: Everyone (Tier I)
	GS175925: HP:0004340 Abnormality of vitamin B metabolism Figure Label: HP:0004340 Species: Homo sapiens  Data Points: 11  Description: Abnormality of vitamin B metabolism Available to: Everyone (Tier I)
	GS136355: novelty/stress induced locomotor activation 6 (Nsila6, Published QTL Chr 8) Figure Label: QTL-Nsila6-Mouse-Chr 8 Species: Mus musculus  Data Points: 528  Description: QTL associated with novelty/stress induced locomotor activation 6. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (84839067) Available to: Everyone (Tier I)
	GS209455: GO:0003824 catalytic activity Figure Label: GO:0003824 Species: Homo sapiens  Data Points: 5321  Description: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS202822: GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Figure Label: GO:0016818 Species: Homo sapiens  Data Points: 793  Description: "Catalysis of the hydrolysis of any acid anhydride which contains phosphorus." [GOC:jl] Available to: Everyone (Tier I)
	GS172666: HP:0011804 Abnormality of muscle physiology Figure Label: HP:0011804 Species: Homo sapiens  Data Points: 832  Description: "A functional abnormality of a skeletal muscle." [HPO:probinson] Available to: Everyone (Tier I)
	GS175107: HP:0003808 Abnormal muscle tone Figure Label: HP:0003808 Species: Homo sapiens  Data Points: 537  Description: Abnormal muscle tone Available to: Everyone (Tier I)
	GS200678: GO:0009235 cobalamin metabolic process Figure Label: GO:0009235 Species: Homo sapiens  Data Points: 7  Description: "The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom." [GOC:go_curators] Available to: Everyone (Tier I)
	GS193061: GO:0044444 cytoplasmic part Figure Label: GO:0044444 Species: Mus musculus  Data Points: 5588  Description: "Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GOC:jl] Available to: Everyone (Tier I)
	GS192624: GO:0043231 intracellular membrane-bounded organelle Figure Label: GO:0043231 Species: Mus musculus  Data Points: 8630  Description: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS200393: GO:0032561 guanyl ribonucleotide binding Figure Label: GO:0032561 Species: Homo sapiens  Data Points: 392  Description: "Interacting selectively and non-covalently with a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] Available to: Everyone (Tier I)
	GS186743: GO:0043227 membrane-bounded organelle Figure Label: GO:0043227 Species: Mus musculus  Data Points: 8650  Description: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
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