Gene Details

Btk and homologs in 4 species are found in 785 GeneSets:

- Entrez   - Ensembl   - GeneNetwork   - STRING   - Allen Brain Atlas   - MGI   - Comparative Toxicogenomics Database  

Select gene sets below using the check boxes, and then add them to a project using the pull down below. You can also create a project using the pull down. To view a set, click on the GeneSetID:GeneSet Description shown in green below.

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	GS185131: GO:0044699 single-organism process Figure Label: GO:0044699 Species: Mus musculus  Data Points: 7755  Description: "A biological process that involves only one organism." [GOC:jl] Available to: Everyone (Tier I)
	GS207306: GO:0080134 regulation of response to stress Figure Label: GO:0080134 Species: Homo sapiens  Data Points: 732  Description: "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:dhl] Available to: Everyone (Tier I)
	GS191217: GO:0045087 innate immune response Figure Label: GO:0045087 Species: Mus musculus  Data Points: 287  Description: "Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens." [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_15nov05, GOC:mtg_sensu] Available to: Everyone (Tier I)
	GS169480: MP:0001876 decreased inflammatory response Figure Label: MP:0001876 Species: Mus musculus  Data Points: 263  Description: "less than expected response to injury, infection, or insult" [MGI:cwg] Available to: Everyone (Tier I)
	GS192507: GO:0006812 cation transport Figure Label: GO:0006812 Species: Mus musculus  Data Points: 782  Description: "The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] Available to: Everyone (Tier I)
	GS170466: MP:0008211 decreased mature B cell number Figure Label: MP:0008211 Species: Mus musculus  Data Points: 262  Description: "reduced number of the mature form of B cells, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex" [CL:0000785, ISBN:0781735149] Available to: Everyone (Tier I)
	GS196653: GO:0001783 B cell apoptotic process Figure Label: GO:0001783 Species: Homo sapiens  Data Points: 17  Description: "The process of apoptosis in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity." [CL:0000236, GOC:add, GOC:mtg_apoptosis, ISBN:0781735149] Available to: Everyone (Tier I)
	GS175490: HP:0000999 Pyoderma Figure Label: HP:0000999 Species: Homo sapiens  Data Points: 2  Description: "Any manifestation of a skin disease associated with the production of pus." [HPO:probinson] Available to: Everyone (Tier I)
	GS169127: MP:0002445 abnormal mononuclear cell differentiation Figure Label: MP:0002445 Species: Mus musculus  Data Points: 1037  Description: "atypical production of or inability to produce a leukocyte with a single non-segmented nucleus in the mature form" [CL:0000842] Available to: Everyone (Tier I)
	GS205510: GO:0001883 purine nucleoside binding Figure Label: GO:0001883 Species: Homo sapiens  Data Points: 1839  Description: "Interacting selectively and non-covalently with a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose." [GOC:hjd] Available to: Everyone (Tier I)
	GS171644: HP:0011842 Abnormality of skeletal morphology Figure Label: HP:0011842 Species: Homo sapiens  Data Points: 1181  Description: "An abnormality of the form, structure, or size of the `skeletal system` (FMA:23881)." [HPO:probinson] Available to: Everyone (Tier I)
	GS175930: HP:0000246 Sinusitis Figure Label: HP:0000246 Species: Homo sapiens  Data Points: 39  Description: "Inflammation of the `paranasal sinuses` (FMA:59679) owing to a viral, bacterial, or fungal infection, allergy, or an autoimmune reaction." [HPO:probinson] Available to: Everyone (Tier I)
	GS189855: GO:0043168 anion binding Figure Label: GO:0043168 Species: Mus musculus  Data Points: 2260  Description: "Interacting selectively and non-covalently with anions, charged atoms or groups of atoms with a net negative charge." [GOC:jl] Available to: Everyone (Tier I)
	GS199676: GO:0008063 Toll signaling pathway Figure Label: GO:0008063 Species: Homo sapiens  Data Points: 81  Description: "A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Toll on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:go_curators, PMID:11135568, PMID:19126860] Available to: Everyone (Tier I)
	GS168559: MP:0002421 abnormal cell-mediated immunity Figure Label: MP:0002421 Species: Mus musculus  Data Points: 1587  Description: "abnormal function of any adaptive immune response in which T cells play a main role" [ISBN:0-8153-1691-7, MGI:cwg] Available to: Everyone (Tier I)
	GS171546: HP:0003729 Enteroviral dermatomyositis syndrome Figure Label: HP:0003729 Species: Homo sapiens  Data Points: 1  Description: Enteroviral dermatomyositis syndrome Available to: Everyone (Tier I)
	GS168327: MP:0008171 abnormal mature B cell morphology Figure Label: MP:0008171 Species: Mus musculus  Data Points: 348  Description: "any structural anomaly of the mature form of a B cell, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex" [CL:0000785, ISBN:0781735149, MGI:csmith] Available to: Everyone (Tier I)
	GS175130: HP:0000750 Delayed speech and language development Figure Label: HP:0000750 Species: Homo sapiens  Data Points: 99  Description: "A degree of language development that is significantly below the norm for a child of a specified age." [HPO:probinson] Available to: Everyone (Tier I)
	GS169830: MP:0005384 cellular phenotype Figure Label: MP:0005384 Species: Mus musculus  Data Points: 3631  Description: cellular phenotype Available to: Everyone (Tier I)
	GS193546: GO:0002279 mast cell activation involved in immune response Figure Label: GO:0002279 Species: Mus musculus  Data Points: 28  Description: "The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] Available to: Everyone (Tier I)
	GS166061: MP:0009332 abnormal splenocyte morphology Figure Label: MP:0009332 Species: Mus musculus  Data Points: 64  Description: "any structural anomaly of a cell of the spleen" [MGI:csmith] Available to: Everyone (Tier I)
	GS169733: MP:0002461 increased immunoglobulin level Figure Label: MP:0002461 Species: Mus musculus  Data Points: 370  Description: "greater than normal immunoglobulin level" [MGI:cwg] Available to: Everyone (Tier I)
	GS172294: HP:0001510 Growth delay Figure Label: HP:0001510 Species: Homo sapiens  Data Points: 645  Description: "A deficiency or slowing down of growth pre- and postnatally." [HPO:probinson] Available to: Everyone (Tier I)
	GS174134: HP:0002012 Abnormality of the abdominal organs Figure Label: HP:0002012 Species: Homo sapiens  Data Points: 845  Description: "An abnormality of the `viscera of the abdomen` (FMA:259123)." [HPO:probinson] Available to: Everyone (Tier I)
	GS184984: GO:0032553 ribonucleotide binding Figure Label: GO:0032553 Species: Mus musculus  Data Points: 1774  Description: "Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] Available to: Everyone (Tier I)
	GS191193: GO:0009607 response to biotic stimulus Figure Label: GO:0009607 Species: Mus musculus  Data Points: 550  Description: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." [GOC:hb] Available to: Everyone (Tier I)
	GS171928: HP:0100577 Urinary bladder inflammation Figure Label: HP:0100577 Species: Homo sapiens  Data Points: 48  Description: "`Inflammation`(MPATH:212) of the `urinary bladder` (FMA:15900)." [HPO:probinson] Available to: Everyone (Tier I)
	GS206251: GO:0016301 kinase activity Figure Label: GO:0016301 Species: Homo sapiens  Data Points: 772  Description: "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS165858: MP:0005000 abnormal immune tolerance Figure Label: MP:0005000 Species: Mus musculus  Data Points: 655  Description: "anomaly in the process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it" [GO:0002507, MGI:csmith] Available to: Everyone (Tier I)
	GS183645: GO:0017076 purine nucleotide binding Figure Label: GO:0017076 Species: Mus musculus  Data Points: 1765  Description: "Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate." [GOC:ai] Available to: Everyone (Tier I)
	GS186548: GO:0035091 phosphatidylinositol binding Figure Label: GO:0035091 Species: Mus musculus  Data Points: 137  Description: "Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives." [GOC:bf, ISBN:0198506732, PMID:11395417] Available to: Everyone (Tier I)
	GS207674: GO:0002697 regulation of immune effector process Figure Label: GO:0002697 Species: Homo sapiens  Data Points: 213  Description: "Any process that modulates the frequency, rate, or extent of an immune effector process." [GOC:add] Available to: Everyone (Tier I)
	GS170969: HP:0000157 Abnormality of the tongue Figure Label: HP:0000157 Species: Homo sapiens  Data Points: 135  Description: "Any abnormality of the `tongue` (FMA:54640)." [HPO:probinson] Available to: Everyone (Tier I)
	GS191019: GO:0034641 cellular nitrogen compound metabolic process Figure Label: GO:0034641 Species: Mus musculus  Data Points: 4619  Description: "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." [GOC:mah] Available to: Everyone (Tier I)
	GS168334: MP:0002619 abnormal lymphocyte morphology Figure Label: MP:0002619 Species: Mus musculus  Data Points: 1460  Description: "any structural anomaly of the cells involved in adaptive immune reactions of the body in most inflammatory and autoimmune diseases, including B cells, T cells and natural killer cells" [MGI:csmith] Available to: Everyone (Tier I)
	GS176107: HP:0000929 Abnormality of the skull Figure Label: HP:0000929 Species: Homo sapiens  Data Points: 786  Description: "An abnormality of the `skull` (FMA:46565), the bony framework of the head which is comprised of eight cranial and fourteen facial bones." [HPO:probinson] Available to: Everyone (Tier I)
	GS187887: GO:0080090 regulation of primary metabolic process Figure Label: GO:0080090 Species: Mus musculus  Data Points: 3776  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [PMID:19211694] Available to: Everyone (Tier I)
	GS165859: MP:0000351 increased cell proliferation Figure Label: MP:0000351 Species: Mus musculus  Data Points: 254  Description: "increase in the expansion rate of a cell population by cell division" [MGI:csmith] Available to: Everyone (Tier I)
	GS203844: GO:0018212 peptidyl-tyrosine modification Figure Label: GO:0018212 Species: Homo sapiens  Data Points: 202  Description: "The modification of peptidyl-tyrosine." [GOC:go_curators] Available to: Everyone (Tier I)
	GS166858: MP:0000685 abnormal immune system morphology Figure Label: MP:0000685 Species: Mus musculus  Data Points: 2406  Description: "any structural anomaly in the organs or cells associated with the development and formation of lymphocytes" [MGI:cwg] Available to: Everyone (Tier I)
	GS163965: MP:0011182 decreased hematopoietic cell number Figure Label: MP:0011182 Species: Mus musculus  Data Points: 1290  Description: "fewer than expected number of cells of the hematopoietic lineage" [MGI:csmith] Available to: Everyone (Tier I)
	GS166749: MP:0002221 abnormal lymph organ size Figure Label: MP:0002221 Species: Mus musculus  Data Points: 1084  Description: "change in the normal size of lymphatic tissues" [MGI:cwg] Available to: Everyone (Tier I)
	GS178334: GO:0007267 cell-cell signaling Figure Label: GO:0007267 Species: Mus musculus  Data Points: 734  Description: "Any process that mediates the transfer of information from one cell to another." [GOC:mah] Available to: Everyone (Tier I)
	GS189669: GO:2000112 regulation of cellular macromolecule biosynthetic process Figure Label: GO:2000112 Species: Mus musculus  Data Points: 2763  Description: "Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process." [GOC:obol] Available to: Everyone (Tier I)
	GS163010: MP:0011181 increased hematopoietic cell number Figure Label: MP:0011181 Species: Mus musculus  Data Points: 1134  Description: "greater than expected number of cells of the hematopoietic lineage" [MGI:csmith] Available to: Everyone (Tier I)
	GS176098: HP:0000927 Abnormality of skeletal maturation Figure Label: HP:0000927 Species: Homo sapiens  Data Points: 149  Description: "The bones of the skeleton undergo a series of characteristic changes in size, shape, and calcification from fetal life until puberty. An abnormality of this process can include delayed or accelerated skeletal maturation, or deviation of some, but not all bones from the expected patterns of maturation." [HPO:probinson] Available to: Everyone (Tier I)
	GS206108: GO:2001141 regulation of RNA biosynthetic process Figure Label: GO:2001141 Species: Homo sapiens  Data Points: 2896  Description: "Any process that modulates the frequency, rate or extent of RNA biosynthetic process." [GOC:dph] Available to: Everyone (Tier I)
	GS170586: MP:0004978 decreased B-1 B cell number Figure Label: MP:0004978 Species: Mus musculus  Data Points: 85  Description: "reduced number of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity" [MGI:csmith] Available to: Everyone (Tier I)
	GS192017: GO:0006139 nucleobase-containing compound metabolic process Figure Label: GO:0006139 Species: Mus musculus  Data Points: 4353  Description: "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:ai] Available to: Everyone (Tier I)
	GS196343: GO:0036094 small molecule binding Figure Label: GO:0036094 Species: Homo sapiens  Data Points: 2625  Description: "Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:pm] Available to: Everyone (Tier I)
	GS172054: HP:0001507 Growth abnormality Figure Label: HP:0001507 Species: Homo sapiens  Data Points: 954  Description: Growth abnormality Available to: Everyone (Tier I)
	GS184917: GO:0002252 immune effector process Figure Label: GO:0002252 Species: Mus musculus  Data Points: 417  Description: "Any process of the immune system that can potentially contribute to an immune response." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS177404: GO:0005737 cytoplasm Figure Label: GO:0005737 Species: Mus musculus  Data Points: 8406  Description: "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] Available to: Everyone (Tier I)
	GS207925: GO:0034645 cellular macromolecule biosynthetic process Figure Label: GO:0034645 Species: Homo sapiens  Data Points: 4169  Description: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS201251: GO:0044424 intracellular part Figure Label: GO:0044424 Species: Homo sapiens  Data Points: 12234  Description: "Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [GOC:jl] Available to: Everyone (Tier I)
	GS193238: GO:0031323 regulation of cellular metabolic process Figure Label: GO:0031323 Species: Mus musculus  Data Points: 3865  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] Available to: Everyone (Tier I)
	GS203908: GO:0016070 RNA metabolic process Figure Label: GO:0016070 Species: Homo sapiens  Data Points: 3917  Description: "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS168992: MP:0005087 decreased acute inflammation Figure Label: MP:0005087 Species: Mus musculus  Data Points: 191  Description: "less than the expected early reaction of the microcirculation, characterized by movement of fluid and leukocytes from the blood into extravascular tissues; initiated by injury, infection, or local immune response" [ISBN:0-397-51047-0] Available to: Everyone (Tier I)
	GS188142: GO:0048856 anatomical structure development Figure Label: GO:0048856 Species: Mus musculus  Data Points: 3597  Description: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021, GOC:mtg_15jun06] Available to: Everyone (Tier I)
	GS177440: GO:0006915 apoptotic process Figure Label: GO:0006915 Species: Mus musculus  Data Points: 1352  Description: "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathways) which typically lead to rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. The process ends when the cell has died. The process is divided into a signaling pathway phase and into an execution phase, which is triggered by the former." [GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263] Available to: Everyone (Tier I)
	GS192508: GO:0006811 ion transport Figure Label: GO:0006811 Species: Mus musculus  Data Points: 1106  Description: "The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] Available to: Everyone (Tier I)
	GS207997: GO:0004713 protein tyrosine kinase activity Figure Label: GO:0004713 Species: Homo sapiens  Data Points: 147  Description: "Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate." [EC:2.7.10] Available to: Everyone (Tier I)
	GS196988: GO:0045595 regulation of cell differentiation Figure Label: GO:0045595 Species: Homo sapiens  Data Points: 1010  Description: "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features." [GOC:go_curators] Available to: Everyone (Tier I)
	GS165866: MP:0000350 abnormal cell proliferation Figure Label: MP:0000350 Species: Mus musculus  Data Points: 876  Description: "anomaly in the ability of the a cell population to undergo expansion by cell division" [ISBN:0-683-40008-8] Available to: Everyone (Tier I)
	GS183543: GO:0051179 localization Figure Label: GO:0051179 Species: Mus musculus  Data Points: 4001  Description: "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location." [GOC:ai] Available to: Everyone (Tier I)
	GS165419: MP:0002491 decreased IgD level Figure Label: MP:0002491 Species: Mus musculus  Data Points: 9  Description: "less than normal immunoglobulin class D level" [MGI:cwg] Available to: Everyone (Tier I)
	GS171126: HP:0000022 Abnormality of male internal genitalia Figure Label: HP:0000022 Species: Homo sapiens  Data Points: 392  Description: "An abnormality of the `male internal genitalia` (FMA:45655)." [HPO:probinson] Available to: Everyone (Tier I)
	GS174338: HP:0002719 Recurrent infections Figure Label: HP:0002719 Species: Homo sapiens  Data Points: 275  Description: "Increased susceptibility to microbial infections, as manifested by recurrent episodes of infection." [HPO:probinson] Available to: Everyone (Tier I)
	GS162953: MP:0002020 increased tumor incidence Figure Label: MP:0002020 Species: Mus musculus  Data Points: 1172  Description: "greater than the expected number of neoplasms in a specific population in a given time period, usually of a specific type" [MESH:E05.318.308.985.525.375, MGI:csmith] Available to: Everyone (Tier I)
	GS165744: MP:0008470 abnormal spleen B cell follicle morphology Figure Label: MP:0008470 Species: Mus musculus  Data Points: 179  Description: "any structural anomaly of the area of the white pulp where the affinity maturation of B cells and the generation of memory B cells and plasma cells occur" [PMID:17495967] Available to: Everyone (Tier I)
	GS175330: HP:0000031 Epididymitis Figure Label: HP:0000031 Species: Homo sapiens  Data Points: 2  Description: "The presence of `inflammation` (MPATH:212) of the `epididymis` (FMA:18255)." [HPO:probinson] Available to: Everyone (Tier I)
	GS205500: GO:0071944 cell periphery Figure Label: GO:0071944 Species: Homo sapiens  Data Points: 4371  Description: "The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures." [GOC:mah] Available to: Everyone (Tier I)
	GS193414: GO:0044249 cellular biosynthetic process Figure Label: GO:0044249 Species: Mus musculus  Data Points: 4114  Description: "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:jl] Available to: Everyone (Tier I)
	GS205334: GO:0051090 regulation of sequence-specific DNA binding transcription factor activity Figure Label: GO:0051090 Species: Homo sapiens  Data Points: 341  Description: "Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:ai] Available to: Everyone (Tier I)
	GS163243: MP:0002362 abnormal spleen marginal zone morphology Figure Label: MP:0002362 Species: Mus musculus  Data Points: 166  Description: "any structural anomaly of the zone between the red and white pulp of the spleen containing numerous macrophages and lymphocytes, and a rich plexus of sinusoids supplied by white pulp arterioles carrying blood-borne antigens" [ISBN:0-683-40008-8] Available to: Everyone (Tier I)
	GS209108: GO:0000166 nucleotide binding Figure Label: GO:0000166 Species: Homo sapiens  Data Points: 2432  Description: "Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose." [GOC:mah, ISBN:0198547684] Available to: Everyone (Tier I)
	GS194599: GO:0002902 regulation of B cell apoptotic process Figure Label: GO:0002902 Species: Homo sapiens  Data Points: 14  Description: "Any process that modulates the frequency, rate, or extent of B cell apoptosis." [GOC:add] Available to: Everyone (Tier I)
	GS173614: HP:0002743 Recurrent enteroviral infections Figure Label: HP:0002743 Species: Homo sapiens  Data Points: 2  Description: "Increased susceptibility to enteroviral infections, as manifested by recurrent episodes of enteroviral infection." [HPO:probinson] Available to: Everyone (Tier I)
	GS167325: MP:0002144 abnormal B cell differentiation Figure Label: MP:0002144 Species: Mus musculus  Data Points: 477  Description: "atypical production of or inability to produce mature B cells, and/or accumulation of B cell precursors" [MGI:csmith] Available to: Everyone (Tier I)
	GS191728: GO:0008289 lipid binding Figure Label: GO:0008289 Species: Mus musculus  Data Points: 650  Description: "Interacting selectively and non-covalently with a lipid." [GOC:ai] Available to: Everyone (Tier I)
	GS163824: MP:0001259 abnormal body weight Figure Label: MP:0001259 Species: Mus musculus  Data Points: 2357  Description: "anomaly in average weight compared to controls" [MGI:cwg] Available to: Everyone (Tier I)
	GS189547: GO:0002441 histamine secretion involved in inflammatory response Figure Label: GO:0002441 Species: Mus musculus  Data Points: 5  Description: "The regulated release of histamine by a cell or group of cells as part of an inflammatory response." [GOC:add, ISBN:0781735149] Available to: Everyone (Tier I)
	GS192643: GO:0048471 perinuclear region of cytoplasm Figure Label: GO:0048471 Species: Mus musculus  Data Points: 388  Description: "Cytoplasm situated near, or occurring around, the nucleus." [GOC:jid] Available to: Everyone (Tier I)
	GS188652: GO:0001882 nucleoside binding Figure Label: GO:0001882 Species: Mus musculus  Data Points: 1745  Description: "Interacting selectively and non-covalently with a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose." [GOC:hjd] Available to: Everyone (Tier I)
	GS169772: MP:0001844 autoimmune response Figure Label: MP:0001844 Species: Mus musculus  Data Points: 627  Description: "condition in which cells and/or antibodies arise from and are directed against one's own tissues" [ISBN:0-683-40008-8] Available to: Everyone (Tier I)
	GS173557: HP:0005372 Abnormality of B cell physiology Figure Label: HP:0005372 Species: Homo sapiens  Data Points: 89  Description: "An abnormality of the physiological functioning of `B cells` (CL:0000236)." [HPO:probinson] Available to: Everyone (Tier I)
	GS175601: HP:0002086 Abnormality of the respiratory system Figure Label: HP:0002086 Species: Homo sapiens  Data Points: 741  Description: "An abnormality of the `respiratory system` (FMA:7158), which include the airways, lungs, and the respiratory muscles." [HPO:probinson] Available to: Everyone (Tier I)
	GS169732: MP:0002462 abnormal granulocyte physiology Figure Label: MP:0002462 Species: Mus musculus  Data Points: 253  Description: "any functional anomaly of neutrophils, eosinophils, or basophils" [MGI:cwg] Available to: Everyone (Tier I)
	GS201799: GO:0032550 purine ribonucleoside binding Figure Label: GO:0032550 Species: Homo sapiens  Data Points: 1836  Description: "Interacting selectively and non-covalently with a purine ribonucleoside, a compound consisting of a purine base linked to ribose." [GOC:mah] Available to: Everyone (Tier I)
	GS176203: HP:0000478 Abnormality of the eye Figure Label: HP:0000478 Species: Homo sapiens  Data Points: 1169  Description: "Any abnormality of the `eye` (FMA:54448), including location, spacing, and intraocular abnormalities." [HPO:curators] Available to: Everyone (Tier I)
	GS188060: GO:0016773 phosphotransferase activity, alcohol group as acceptor Figure Label: GO:0016773 Species: Mus musculus  Data Points: 672  Description: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor)." [GOC:jl] Available to: Everyone (Tier I)
	GS193550: GO:0002274 myeloid leukocyte activation Figure Label: GO:0002274 Species: Mus musculus  Data Points: 115  Description: "A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:add, ISBN:0781735149] Available to: Everyone (Tier I)
	GS194455: GO:0051239 regulation of multicellular organismal process Figure Label: GO:0051239 Species: Homo sapiens  Data Points: 1770  Description: "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai, GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS169731: MP:0002463 abnormal neutrophil physiology Figure Label: MP:0002463 Species: Mus musculus  Data Points: 177  Description: "abnormal function of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes" [ISBN:0721601464] Available to: Everyone (Tier I)
	GS208131: GO:0045087 innate immune response Figure Label: GO:0045087 Species: Homo sapiens  Data Points: 533  Description: "Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens." [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_15nov05, GOC:mtg_sensu] Available to: Everyone (Tier I)
	GS165414: MP:0002498 abnormal acute inflammation Figure Label: MP:0002498 Species: Mus musculus  Data Points: 331  Description: "aberrant early and often transient reaction of the microcirculation, characterized by movement of fluid and leukocytes from the blood into extravascular tissues; initiated by injury, infection, or local immune response" [ISBN:0-397-51047-0, ISBN:0-8153-1691-7] Available to: Everyone (Tier I)
	GS171226: HP:0000812 Abnormal internal genitalia Figure Label: HP:0000812 Species: Homo sapiens  Data Points: 492  Description: "An anomaly of the adnexa, uterus, and vagina (in female) orseminal tract and prostate (in male)." [HPO:probinson] Available to: Everyone (Tier I)
	GS180852: GO:0006954 inflammatory response Figure Label: GO:0006954 Species: Mus musculus  Data Points: 388  Description: "The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages." [GO_REF:0000022, GOC:mtg_15nov05, ISBN:0198506732] Available to: Everyone (Tier I)
	GS206237: GO:0042981 regulation of apoptotic process Figure Label: GO:0042981 Species: Homo sapiens  Data Points: 1160  Description: "Any process that modulates the occurrence or rate of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] Available to: Everyone (Tier I)
	GS168063: MP:0000313 abnormal cell death Figure Label: MP:0000313 Species: Mus musculus  Data Points: 1435  Description: "any anomaly in the cessation of function at the cellular level" [ISBN:0-683-40008-8] Available to: Everyone (Tier I)
	GS167829: MP:0008484 decreased spleen germinal center size Figure Label: MP:0008484 Species: Mus musculus  Data Points: 32  Description: "reduced size of spleen secondary B follicles where rapid B-cell proliferation, somatic hypermutation, and selection for antigen binding occurs" [PMID:17495967] Available to: Everyone (Tier I)
	GS194876: GO:0042113 B cell activation Figure Label: GO:0042113 Species: Homo sapiens  Data Points: 164  Description: "The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [GOC:mgi_curators, ISBN:0781735140] Available to: Everyone (Tier I)
	GS174756: HP:0011947 Respiratory tract infection Figure Label: HP:0011947 Species: Homo sapiens  Data Points: 197  Description: "An infection of the upper or lower respiratory tract." [HPO:probinson] Available to: Everyone (Tier I)
	GS162982: MP:0002357 abnormal spleen white pulp morphology Figure Label: MP:0002357 Species: Mus musculus  Data Points: 361  Description: "any structural anomaly of the parenchymatous tissue of the spleen that surrounds splenic blood vessels, consists of compact masses of lymphatic cells and is where foreign material removed from the blood is used to initiate an immune reaction that results in the production of antibodies" [MGI:csmith] Available to: Everyone (Tier I)
	GS201696: GO:0010941 regulation of cell death Figure Label: GO:0010941 Species: Homo sapiens  Data Points: 1202  Description: "Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS175982: HP:0000162 Glossoptosis Figure Label: HP:0000162 Species: Homo sapiens  Data Points: 9  Description: "Posterior displacement of the tongue into the pharynx, i.e., a `tongue` (FMA:54640) that is `mislocalised posteriorly` (PATO:0001922)." [HPO:probinson, pmid:19125428] Available to: Everyone (Tier I)
	GS201367: GO:0019538 protein metabolic process Figure Label: GO:0019538 Species: Homo sapiens  Data Points: 3885  Description: "The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification." [GOC:ma] Available to: Everyone (Tier I)
	GS192299: GO:0006793 phosphorus metabolic process Figure Label: GO:0006793 Species: Mus musculus  Data Points: 2565  Description: "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." [GOC:ai] Available to: Everyone (Tier I)
	GS208716: GO:2000026 regulation of multicellular organismal development Figure Label: GO:2000026 Species: Homo sapiens  Data Points: 1096  Description: "Any process that modulates the frequency, rate or extent of multicellular organismal development." [GOC:obol] Available to: Everyone (Tier I)
	GS196808: GO:0032501 multicellular organismal process Figure Label: GO:0032501 Species: Homo sapiens  Data Points: 5637  Description: "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb] Available to: Everyone (Tier I)
	GS171708: HP:0000359 Abnormality of the inner ear Figure Label: HP:0000359 Species: Homo sapiens  Data Points: 384  Description: "An abnormality of the `inner ear` (FMA:60909)." [HPO:probinson] Available to: Everyone (Tier I)
	GS178913: GO:0042221 response to chemical stimulus Figure Label: GO:0042221 Species: Mus musculus  Data Points: 2192  Description: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." [GOC:jl] Available to: Everyone (Tier I)
	GS186744: GO:0043226 organelle Figure Label: GO:0043226 Species: Mus musculus  Data Points: 9740  Description: "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS182835: GO:0005622 intracellular Figure Label: GO:0005622 Species: Mus musculus  Data Points: 11364  Description: "The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS182703: GO:0051171 regulation of nitrogen compound metabolic process Figure Label: GO:0051171 Species: Mus musculus  Data Points: 3021  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] Available to: Everyone (Tier I)
	GS203482: GO:0044093 positive regulation of molecular function Figure Label: GO:0044093 Species: Homo sapiens  Data Points: 1087  Description: "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl] Available to: Everyone (Tier I)
	GS177156: GO:0018108 peptidyl-tyrosine phosphorylation Figure Label: GO:0018108 Species: Mus musculus  Data Points: 208  Description: "The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine." [RESID:AA0039] Available to: Everyone (Tier I)
	GS186790: GO:0006725 cellular aromatic compound metabolic process Figure Label: GO:0006725 Species: Mus musculus  Data Points: 4500  Description: "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells." [GOC:ai, ISBN:0198506732] Available to: Everyone (Tier I)
	GS197619: GO:0005543 phospholipid binding Figure Label: GO:0005543 Species: Homo sapiens  Data Points: 494  Description: "Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS194111: GO:0097159 organic cyclic compound binding Figure Label: GO:0097159 Species: Homo sapiens  Data Points: 5452  Description: "Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure." [CHEBI:33832, GOC:sjw, PMID:7583672] Available to: Everyone (Tier I)
	GS167993: MP:0002403 abnormal pre-B cell morphology Figure Label: MP:0002403 Species: Mus musculus  Data Points: 150  Description: "any structural anomaly of the cells in the B lymphocyte lineage that have undergone VDJ rearrangement of the immunoglobulin heavy chain and are in the process of V-J rearrangement of the light chain: these cells express mu heavy chain on the cell surface" [ISBN:0-8153-1691-7, MGI:cwg] Available to: Everyone (Tier I)
	GS171645: HP:0011843 Abnormality of skeletal physiology Figure Label: HP:0011843 Species: Homo sapiens  Data Points: 266  Description: "An abnormality of the function of the `skeletal system` (FMA:23881)." [HPO:probinson] Available to: Everyone (Tier I)
	GS800: UCSD_CEREBELLUM_Additive_Time_Pattern_4th Figure Label: UCSD_CEREBELLUM_Additive Species: Mus musculus  Data Points: 264  Description: UCSD_CEREBELLUM_Additive_Time_Pattern_4th Available to: Everyone (Tier III)
	GS170110: MP:0003725 increased autoantibody level Figure Label: MP:0003725 Species: Mus musculus  Data Points: 231  Description: "elevated level of antibodies to self-antigens present in the sera; often indicative of autoimmune disease" [MGI:acv, MGI:csmith] Available to: Everyone (Tier I)
	GS184448: GO:0044425 membrane part Figure Label: GO:0044425 Species: Mus musculus  Data Points: 6473  Description: "Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:jl] Available to: Everyone (Tier I)
	GS175933: HP:0000245 Abnormality of the sinuses Figure Label: HP:0000245 Species: Homo sapiens  Data Points: 52  Description: "Abnormality of the paranasal (cranial) sinuses, which are air-filled spaces that are located within the bones of the skull and face and communicate with the nasal cavity. They comprise the maxillary sinuses, the frontal sinuses, the ethmoid sinuses, and the sphenoid sinuses." [HPO:curators] Available to: Everyone (Tier I)
	GS173134: HP:0003095 Septic arthritis Figure Label: HP:0003095 Species: Homo sapiens  Data Points: 2  Description: Septic arthritis Available to: Everyone (Tier I)
	GS166118: MP:0002109 abnormal limb morphology Figure Label: MP:0002109 Species: Mus musculus  Data Points: 857  Description: "any structural anomaly of the projecting paired appendages of an animal trunk, used in particular for movement and grasping; usually denotes the arm and/or legs in mammalian species" [MGI:csmith] Available to: Everyone (Tier I)
	GS197666: GO:0051249 regulation of lymphocyte activation Figure Label: GO:0051249 Species: Homo sapiens  Data Points: 290  Description: "Any process that modulates the frequency, rate or extent of lymphocyte activation." [GOC:ai] Available to: Everyone (Tier I)
	GS204871: GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Figure Label: GO:0002822 Species: Homo sapiens  Data Points: 82  Description: "Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] Available to: Everyone (Tier I)
	GS206742: GO:0043167 ion binding Figure Label: GO:0043167 Species: Homo sapiens  Data Points: 5810  Description: "Interacting selectively and non-covalently with ions, charged atoms or groups of atoms." [GOC:jl] Available to: Everyone (Tier I)
	GS189751: GO:0050794 regulation of cellular process Figure Label: GO:0050794 Species: Mus musculus  Data Points: 8386  Description: "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators] Available to: Everyone (Tier I)
	GS173534: HP:0001877 Abnormality of erythrocytes Figure Label: HP:0001877 Species: Homo sapiens  Data Points: 246  Description: "An abnormality of `erythrocytes` (CL:0000232) (red-blood cells)." [HPO:probinson] Available to: Everyone (Tier I)
	GS197268: GO:0070227 lymphocyte apoptotic process Figure Label: GO:0070227 Species: Homo sapiens  Data Points: 40  Description: "The process of apoptosis in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] Available to: Everyone (Tier I)
	GS187343: GO:0006351 transcription, DNA-dependent Figure Label: GO:0006351 Species: Mus musculus  Data Points: 2588  Description: "The cellular synthesis of RNA on a template of DNA." [GOC:jl, GOC:txnOH] Available to: Everyone (Tier I)
	GS207178: GO:0050867 positive regulation of cell activation Figure Label: GO:0050867 Species: Homo sapiens  Data Points: 241  Description: "Any process that activates or increases the frequency, rate or extent of activation." [GOC:ai] Available to: Everyone (Tier I)
	GS126584: Tetrachlorodibenzodioxin interacting genes (MeSH:D013749) in CTD Figure Label: D013749 [CTD] Species: Homo sapiens  Data Points: 6285  Description: Genes that interact with the MeSH term 'Tetrachlorodibenzodioxin' (D013749). Incorporates data from 726 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene. Available to: Everyone (Tier I)
	GS164115: MP:0000222 decreased neutrophil cell number Figure Label: MP:0000222 Species: Mus musculus  Data Points: 85  Description: "reduced count of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes" [CL:0000775, MGI:csmith] Available to: Everyone (Tier I)
	GS171815: HP:0001574 Abnormality of the integument Figure Label: HP:0001574 Species: Homo sapiens  Data Points: 1073  Description: "An abnormality of the `integument` (FMA:74657), which consists of the skin and the superficial fascia." [HPO:probinson] Available to: Everyone (Tier I)
	GS187175: GO:0045321 leukocyte activation Figure Label: GO:0045321 Species: Mus musculus  Data Points: 535  Description: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor." [GOC:add] Available to: Everyone (Tier I)
	GS200566: GO:0019724 B cell mediated immunity Figure Label: GO:0019724 Species: Homo sapiens  Data Points: 119  Description: "Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS170791: HP:0010978 Abnormality of immune system physiology Figure Label: HP:0010978 Species: Homo sapiens  Data Points: 403  Description: "A functional abnormality of the `immune system` (FMA:9825)." [HPO:probinson, MP:0001790] Available to: Everyone (Tier I)
	GS181473: GO:0005488 binding Figure Label: GO:0005488 Species: Mus musculus  Data Points: 10879  Description: "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." [GOC:ceb, GOC:mah, ISBN:0198506732] Available to: Everyone (Tier I)
	GS167008: MP:0008164 abnormal B-1a B cell morphology Figure Label: MP:0008164 Species: Mus musculus  Data Points: 63  Description: "any structural anomaly of the B-1 B cell subset bearing the CD5 surface marker" [CL:0000820, MGI:csmith, PMID:11861604] Available to: Everyone (Tier I)
	GS175526: HP:0000005 Mode of inheritance Figure Label: HP:0000005 Species: Homo sapiens  Data Points: 2121  Description: "The pattern in which a particular genetic trait or disorder is passed from one generation to the next." [HPO:probinson] Available to: Everyone (Tier I)
	GS180036: GO:0032501 multicellular organismal process Figure Label: GO:0032501 Species: Mus musculus  Data Points: 5892  Description: "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb] Available to: Everyone (Tier I)
	GS196930: GO:0065007 biological regulation Figure Label: GO:0065007 Species: Homo sapiens  Data Points: 8622  Description: "Any process that modulates a measurable attribute of any biological process, quality or function." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] Available to: Everyone (Tier I)
	GS200312: GO:0019219 regulation of nucleobase-containing compound metabolic process Figure Label: GO:0019219 Species: Homo sapiens  Data Points: 3401  Description: "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] Available to: Everyone (Tier I)
	GS167631: MP:0005464 abnormal platelet physiology Figure Label: MP:0005464 Species: Mus musculus  Data Points: 110  Description: "any functional anomaly of the non-nucleated cells found in the blood and involved in blood coagulation" [MESH:A11.118.188, MGI:cwg] Available to: Everyone (Tier I)
	GS197694: GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Figure Label: GO:0002460 Species: Homo sapiens  Data Points: 190  Description: "An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies). An example of this is the adaptive immune response found in Mus musculus." [GOC:add, GOC:mtg_sensu, ISBN:0781735149] Available to: Everyone (Tier I)
	GS192512: GO:0003824 catalytic activity Figure Label: GO:0003824 Species: Mus musculus  Data Points: 5103  Description: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS163230: MP:0008168 decreased B-1a cell number Figure Label: MP:0008168 Species: Mus musculus  Data Points: 44  Description: "reduced number of the B-1 B cell subset bearing the CD5 surface marker" [CL:0000820, PMID:11861604] Available to: Everyone (Tier I)
	GS167823: MP:0008482 decreased spleen germinal center number Figure Label: MP:0008482 Species: Mus musculus  Data Points: 34  Description: "reduced number of spleen secondary B follicles where rapid B-cell proliferation, somatic hypermutation, and selection for antigen binding occurs" [PMID:17495967] Available to: Everyone (Tier I)
	GS163611: MP:0008783 decreased B cell apoptosis Figure Label: MP:0008783 Species: Mus musculus  Data Points: 26  Description: "reduction in the timing or the number of B cells undergoing programmed cell death" [MGI:csmith] Available to: Everyone (Tier I)
	GS180644: GO:0032549 ribonucleoside binding Figure Label: GO:0032549 Species: Mus musculus  Data Points: 1736  Description: "Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose." [GOC:mah] Available to: Everyone (Tier I)
	GS180826: GO:0005543 phospholipid binding Figure Label: GO:0005543 Species: Mus musculus  Data Points: 425  Description: "Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS207616: GO:0016020 membrane Figure Label: GO:0016020 Species: Homo sapiens  Data Points: 7808  Description: "Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:mah, ISBN:0815316194] Available to: Everyone (Tier I)
	GS200569: GO:0019722 calcium-mediated signaling Figure Label: GO:0019722 Species: Homo sapiens  Data Points: 90  Description: "Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions." [GOC:signaling] Available to: Everyone (Tier I)
	GS210574: GO:0002712 regulation of B cell mediated immunity Figure Label: GO:0002712 Species: Homo sapiens  Data Points: 33  Description: "Any process that modulates the frequency, rate, or extent of B cell mediated immunity." [GOC:add] Available to: Everyone (Tier I)
	GS127028: Mifepristone interacting genes (MeSH:D015735) in CTD Figure Label: D015735 [CTD] Species: Homo sapiens  Data Points: 308  Description: Genes that interact with the MeSH term 'Mifepristone' (D015735). Incorporates data from 112 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene. Available to: Everyone (Tier I)
	GS210170: GO:0030097 hemopoiesis Figure Label: GO:0030097 Species: Homo sapiens  Data Points: 497  Description: "The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates." [GOC:dgh, ISBN:0198506732] Available to: Everyone (Tier I)
	GS169303: MP:0008250 abnormal myeloid leukocyte morphology Figure Label: MP:0008250 Species: Mus musculus  Data Points: 798  Description: "any structural anomaly of a cell of the monocyte, granulocyte, or mast cell lineage" [CL:0000766] Available to: Everyone (Tier I)
	GS180229: GO:0005886 plasma membrane Figure Label: GO:0005886 Species: Mus musculus  Data Points: 3614  Description: "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363] Available to: Everyone (Tier I)
	GS169389: MP:0002060 abnormal skin morphology Figure Label: MP:0002060 Species: Mus musculus  Data Points: 1104  Description: "any structural anomaly of the membranous protective covering of the body" [ISBN:0-683-40008-8, PMID:10469309] Available to: Everyone (Tier I)
	GS86609: Table S2: Cocaine regulation of gene expression in the OFC: Effects of DeltaFosB and DeltaJunD Table S2a. Genes Significantly Regulated by Chronic Cocaine [DRG] provisional Figure Label: Chronic cocaine transfected with GFP - Cocaine hydrochloride vs. Saline Species: Rattus norvegicus  Data Points: 64  Description: Chronic cocaine transfected with GFP - Cocaine hydrochloride vs. Saline Viral-mediated gene transfer and DNA microarray Down-regulated gene expression Rats received intra-orbitofrontal injections of adeno-associated virus-green fluorescent protein, or adeno-associated virus-DeltaJunD, followed by injections twice a day for 21 days with either cocaine hydrochloride (15 mg / kg / ml, Intraperitoneal) dissolved in 0.9% sterile saline, or vehicle alone. At least 8 hr elapsed between the first and second daily injections. t-test, ANOVA Cocaine downregulated this gene in the presence of GFP. Using the MAS 5.0 generated gene list of present and absent calls, genes were only analyzed if found to have a statistically significant signal in at least one of the experimental conditions (reducing gene list from approximately 30,000 genes to approximately 19,000 genes). We generated our differentially expressed gene lists using fold change primary criteria with a non-stringent p-value cutoff. Each differentially expressed gene list was generated by creating a volcano plot comparing each experimental condition (Cocaine-GFP) to the control condition (Saline-GFP). We selected genes >1.3 fold differentially expressed with a p<0.05 using a parametric t-test corrected for multiple comparisons. (NIF Table ID 11 [13.5]) Available to: Everyone (Tier I)
	GS167542: MP:0001790 abnormal immune system physiology Figure Label: MP:0001790 Species: Mus musculus  Data Points: 2955  Description: "deviation from the normal function of the immune system" [MGI:cwg] Available to: Everyone (Tier I)
	GS204919: GO:0016772 transferase activity, transferring phosphorus-containing groups Figure Label: GO:0016772 Species: Homo sapiens  Data Points: 899  Description: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] Available to: Everyone (Tier I)
	GS204746: GO:0080090 regulation of primary metabolic process Figure Label: GO:0080090 Species: Homo sapiens  Data Points: 4314  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [PMID:19211694] Available to: Everyone (Tier I)
	GS165428: MP:0005153 abnormal B cell proliferation Figure Label: MP:0005153 Species: Mus musculus  Data Points: 191  Description: "anomaly in the ability of the B cell population to undergo rapid expansion by cell division in response to stimuli" [MGI:csmith, MGI:cwg] Available to: Everyone (Tier I)
	GS205321: GO:0031410 cytoplasmic vesicle Figure Label: GO:0031410 Species: Homo sapiens  Data Points: 928  Description: "A vesicle formed of membrane or protein, found in the cytoplasm of a cell." [GOC:mah] Available to: Everyone (Tier I)
	GS163601: MP:0002089 abnormal postnatal growth/weight/body size Figure Label: MP:0002089 Species: Mus musculus  Data Points: 3437  Description: "increased or decreased average body size, weight or growth characteristic abnormalities manifesting after birth" [MGI:csmith] Available to: Everyone (Tier I)
	GS197244: GO:0044237 cellular metabolic process Figure Label: GO:0044237 Species: Homo sapiens  Data Points: 8595  Description: "The chemical reactions and pathways by which individual cells transform chemical substances." [GOC:go_curators] Available to: Everyone (Tier I)
	GS168851: MP:0002451 abnormal macrophage physiology Figure Label: MP:0002451 Species: Mus musculus  Data Points: 395  Description: "any functional anomaly of the large mononuclear phagocytes which differentiate from monocytes, are typically resident in a particular tissue, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells" [CL:0000235, MGI:csmith] Available to: Everyone (Tier I)
	GS193991: GO:0048731 system development Figure Label: GO:0048731 Species: Homo sapiens  Data Points: 3513  Description: "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:dph, GOC:jid] Available to: Everyone (Tier I)
	GS163491: MP:0003304 large intestinal inflammation Figure Label: MP:0003304 Species: Mus musculus  Data Points: 173  Description: "local accumulation of fluid, plasma proteins, and leukocytes in the large intestine" [NCBI:matt] Available to: Everyone (Tier I)
	GS198456: GO:0019438 aromatic compound biosynthetic process Figure Label: GO:0019438 Species: Homo sapiens  Data Points: 3626  Description: "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai] Available to: Everyone (Tier I)
	GS863: Differential expression across development in Sey Pax6 mutants and controls in an inverted-U (downward parabola). Figure Label: SeyPax6AgeInvertedU Species: Mus musculus  Data Points: 936  Description: Differential Cerebellum gene expression across three development time points in Sey Pax6 mutants and controls in an inverted-U (downward parabola). Available to: Everyone (Tier III)
	GS163294: MP:0000218 increased leukocyte cell number Figure Label: MP:0000218 Species: Mus musculus  Data Points: 1001  Description: "greater than normal number of nucleated cells of the myeloid or lymphoid lineages, found in blood or other tissue" [CL:0000738, MESH:A11.118.637] Available to: Everyone (Tier I)
	GS181667: GO:0019438 aromatic compound biosynthetic process Figure Label: GO:0019438 Species: Mus musculus  Data Points: 2907  Description: "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai] Available to: Everyone (Tier I)
	GS209998: GO:0002758 innate immune response-activating signal transduction Figure Label: GO:0002758 Species: Homo sapiens  Data Points: 131  Description: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an innate immune response." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05] Available to: Everyone (Tier I)
	GS128586: Rotarod Baseline Chr# X Figure Label: QTL-Rotarod Baseline-Mouse-ChrX Species: Mus musculus  Data Points: 685  Description: Rotarod Baseline Chr# X rs3702256 (131483732) with right flanking marker CEL-X_106858553 (112637354) and left marker gnfX.148.995 (165265639). This was mapped in 300 + (b6x129)F2 mice. Available to: Everyone (Tier I)
	GS171558: HP:0000389 Chronic otitis media Figure Label: HP:0000389 Species: Homo sapiens  Data Points: 7  Description: "Chronic otitis media refers to fluid, swelling, or infection of the middle ear that does not heal and may cause permanent damage to the ear." [HPO:probinson] Available to: Everyone (Tier I)
	GS174948: HP:0100763 Abnormality of the lymphatic system Figure Label: HP:0100763 Species: Homo sapiens  Data Points: 271  Description: "An anomaly of the lymphatic system, a network of lymphatic vessels that carry a clear fluid called lymph unidirectionally towards either the right lymphatic duct or the thoracic duct, which in turn drain into the right and left subclavian veins respectively." [HPO:probinson] Available to: Everyone (Tier I)
	GS188511: GO:0010468 regulation of gene expression Figure Label: GO:0010468 Species: Mus musculus  Data Points: 3090  Description: "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS165527: MP:0005378 growth/size phenotype Figure Label: MP:0005378 Species: Mus musculus  Data Points: 4173  Description: growth/size phenotype Available to: Everyone (Tier I)
	GS169728: MP:0002467 impaired neutrophil phagocytosis Figure Label: MP:0002467 Species: Mus musculus  Data Points: 12  Description: "reduced ability of neutrophils to internalize particulate matter" [ISBN:0-8153-1691-7, MGI:cwg] Available to: Everyone (Tier I)
	GS205607: GO:0002768 immune response-regulating cell surface receptor signaling pathway Figure Label: GO:0002768 Species: Homo sapiens  Data Points: 142  Description: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response." [GOC:add, ISBN:0781735149, PMID:15771571] Available to: Everyone (Tier I)
	GS175158: HP:0011747 Abnormality of the anterior pituitary Figure Label: HP:0011747 Species: Homo sapiens  Data Points: 73  Description: "An abnormality of the `adenohypophysis` (FMA:74627), which is also known as the anterior lobe of the pituitary gland." [DDD:spark] Available to: Everyone (Tier I)
	GS175529: HP:0000001 All Figure Label: HP:0000001 Species: Homo sapiens  Data Points: 2374  Description: All Available to: Everyone (Tier I)
	GS165418: MP:0002490 abnormal immunoglobulin level Figure Label: MP:0002490 Species: Mus musculus  Data Points: 596  Description: "deviation from the normal levels of glycoproteins present in the blood and other tissue, often functioning as antibodies" [ISBN:0-683-40008-8, MGI:cwg] Available to: Everyone (Tier I)
	GS209199: GO:0007165 signal transduction Figure Label: GO:0007165 Species: Homo sapiens  Data Points: 4084  Description: "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11] Available to: Everyone (Tier I)
	GS198323: GO:0046872 metal ion binding Figure Label: GO:0046872 Species: Homo sapiens  Data Points: 3934  Description: "Interacting selectively and non-covalently with any metal ion." [GOC:ai] Available to: Everyone (Tier I)
	GS210285: GO:0071887 leukocyte apoptotic process Figure Label: GO:0071887 Species: Homo sapiens  Data Points: 55  Description: "The process of apoptosis in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:BHF, GOC:mah, GOC:mtg_apoptosis] Available to: Everyone (Tier I)
	GS199781: GO:0043067 regulation of programmed cell death Figure Label: GO:0043067 Species: Homo sapiens  Data Points: 1174  Description: "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] Available to: Everyone (Tier I)
	GS190471: GO:0005829 cytosol Figure Label: GO:0005829 Species: Mus musculus  Data Points: 939  Description: "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes." [GOC:hgd, GOC:jl] Available to: Everyone (Tier I)
	GS185206: GO:0045055 regulated secretory pathway Figure Label: GO:0045055 Species: Mus musculus  Data Points: 42  Description: "A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand." [GOC:mah, ISBN:0716731363] Available to: Everyone (Tier I)
	GS165740: MP:0008474 absent spleen germinal center Figure Label: MP:0008474 Species: Mus musculus  Data Points: 35  Description: "absence of the area of the spleen secondary B follicle where rapid B-cell proliferation, somatic hypermutation, and selection for antigen binding occurs" [PMID:17495967] Available to: Everyone (Tier I)
	GS169767: MP:0002396 abnormal hematopoietic system morphology/development Figure Label: MP:0002396 Species: Mus musculus  Data Points: 2754  Description: "any structural or developmental anomaly of the blood cells or the organs associated with the development and formation of blood cells" [MGI:cwg] Available to: Everyone (Tier I)
	GS175822: HP:0002090 Pneumonia Figure Label: HP:0002090 Species: Homo sapiens  Data Points: 42  Description: "Inflammation of any part of the lung parenchyma." [HPO:probinson] Available to: Everyone (Tier I)
	GS184447: GO:0044424 intracellular part Figure Label: GO:0044424 Species: Mus musculus  Data Points: 11124  Description: "Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [GOC:jl] Available to: Everyone (Tier I)
	GS206737: GO:0043168 anion binding Figure Label: GO:0043168 Species: Homo sapiens  Data Points: 2392  Description: "Interacting selectively and non-covalently with anions, charged atoms or groups of atoms with a net negative charge." [GOC:jl] Available to: Everyone (Tier I)
	GS187067: GO:0046879 hormone secretion Figure Label: GO:0046879 Species: Mus musculus  Data Points: 205  Description: "The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS193236: GO:0031326 regulation of cellular biosynthetic process Figure Label: GO:0031326 Species: Mus musculus  Data Points: 2947  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] Available to: Everyone (Tier I)
	GS188577: GO:0000302 response to reactive oxygen species Figure Label: GO:0000302 Species: Mus musculus  Data Points: 95  Description: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." [GOC:krc] Available to: Everyone (Tier I)
	GS207673: GO:0002694 regulation of leukocyte activation Figure Label: GO:0002694 Species: Homo sapiens  Data Points: 330  Description: "Any process that modulates the frequency, rate, or extent of leukocyte activation." [GOC:add] Available to: Everyone (Tier I)
	GS209863: GO:0050896 response to stimulus Figure Label: GO:0050896 Species: Homo sapiens  Data Points: 6585  Description: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." [GOC:ai, GOC:bf] Available to: Everyone (Tier I)
	GS136739: small testis weight 2 (Smtw2, Published QTL Chr X) Figure Label: QTL-Smtw2-Mouse-Chr X Species: Mus musculus  Data Points: 310  Description: QTL associated with small testis weight 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (138191357) Available to: Everyone (Tier I)
	GS204918: GO:0016773 phosphotransferase activity, alcohol group as acceptor Figure Label: GO:0016773 Species: Homo sapiens  Data Points: 717  Description: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor)." [GOC:jl] Available to: Everyone (Tier I)
	GS169777: MP:0002398 abnormal bone marrow cell morphology/development Figure Label: MP:0002398 Species: Mus musculus  Data Points: 1410  Description: "any structural anomaly of the cells found in the bone marrow" [MGI:cwg] Available to: Everyone (Tier I)
	GS166513: MP:0008195 abnormal antigen presenting cell morphology Figure Label: MP:0008195 Species: Mus musculus  Data Points: 767  Description: "any structural anomaly of a cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response" [CL:0000145, ISBN:0781735149, MGI:csmith] Available to: Everyone (Tier I)
	GS165035: MP:0008202 absent B-1 B cells Figure Label: MP:0008202 Species: Mus musculus  Data Points: 19  Description: "absence of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and are enriched for self-reactivity; B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas" [CL:0000819, MGI:csmith, PMID:11861604] Available to: Everyone (Tier I)
	GS169880: MP:0009676 abnormal hemostasis Figure Label: MP:0009676 Species: Mus musculus  Data Points: 282  Description: "any anomaly in the spontaneous arrest of bleeding from vessels carrying blood under pressure or the arrest of circulation to an organ or part" [MESH:G09.188.124.560, MGI:anna] Available to: Everyone (Tier I)
	GS176021: HP:0010927 Abnormality of divalent inorganic cation homeostasis Figure Label: HP:0010927 Species: Homo sapiens  Data Points: 60  Description: "An abnormality of `divalent inorganic cation homeostasis` (GO:0072507)." [HPO:probinson] Available to: Everyone (Tier I)
	GS163080: MP:0010273 increased classified tumor incidence Figure Label: MP:0010273 Species: Mus musculus  Data Points: 931  Description: "greater than the expected number of tumors with a specific classification type in a given population in a given time period" [MGI:csmith] Available to: Everyone (Tier I)
	GS176008: HP:0010701 Abnormal immunoglobulin level Figure Label: HP:0010701 Species: Homo sapiens  Data Points: 87  Description: "An abnormal deviation from normal levels of immunoglobulins in blood." [HPO:probinson] Available to: Everyone (Tier I)
	GS191021: GO:0034645 cellular macromolecule biosynthetic process Figure Label: GO:0034645 Species: Mus musculus  Data Points: 3382  Description: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS199499: GO:0051171 regulation of nitrogen compound metabolic process Figure Label: GO:0051171 Species: Homo sapiens  Data Points: 3487  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] Available to: Everyone (Tier I)
	GS177598: GO:0043412 macromolecule modification Figure Label: GO:0043412 Species: Mus musculus  Data Points: 2303  Description: "The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties." [GOC:go_curators] Available to: Everyone (Tier I)
	GS172422: HP:0012115 Hepatitis Figure Label: HP:0012115 Species: Homo sapiens  Data Points: 14  Description: "Inflammation of the liver." [HPO:probinson] Available to: Everyone (Tier I)
	GS203335: GO:0048513 organ development Figure Label: GO:0048513 Species: Homo sapiens  Data Points: 2545  Description: "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dph, GOC:jid] Available to: Everyone (Tier I)
	GS190794: GO:0002349 histamine production involved in inflammatory response Figure Label: GO:0002349 Species: Mus musculus  Data Points: 5  Description: "The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149, PMID:16730260] Available to: Everyone (Tier I)
	GS186740: GO:0043229 intracellular organelle Figure Label: GO:0043229 Species: Mus musculus  Data Points: 9717  Description: "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS169409: MP:0004939 abnormal B cell morphology Figure Label: MP:0004939 Species: Mus musculus  Data Points: 698  Description: "any structural anomaly of lymphocytes that expresses membrane-bound immunoglobulin complexes in the mature form, and differentiate into antibody-secreting plasma cells and memory cells upon interaction with antigen; B cells are the primary lymphocyte responsible for humoral immunity, and are most effective against extracellular pathogens" [CL:0000236, MGI:csmith] Available to: Everyone (Tier I)
	GS136144: lithogenic gene 4 (Lith4, Published QTL Chr X) Figure Label: QTL-Lith4-Mouse-Chr X Species: Mus musculus  Data Points: 299  Description: QTL associated with lithogenic gene 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (124541535) Available to: Everyone (Tier I)
	GS163589: MP:0005017 decreased B cell number Figure Label: MP:0005017 Species: Mus musculus  Data Points: 451  Description: "fewer than normal number of cells that are formed in the bone marrow, migrate to the peripheral lymphatic system, and mature into plasma cells or memory cells; these cells are involved in humoral immunity" [ISBN:0-8036-0655-99, MGI:smb] Available to: Everyone (Tier I)
	GS206414: GO:0002449 lymphocyte mediated immunity Figure Label: GO:0002449 Species: Homo sapiens  Data Points: 177  Description: "Any process involved in the carrying out of an immune response by a lymphocyte." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS208010: GO:0002368 B cell cytokine production Figure Label: GO:0002368 Species: Homo sapiens  Data Points: 2  Description: "Any process that contributes to cytokine production by a B cell." [GOC:add, ISBN:0781735149] Available to: Everyone (Tier I)
	GS197087: GO:0016310 phosphorylation Figure Label: GO:0016310 Species: Homo sapiens  Data Points: 1263  Description: "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS170649: MP:0002346 abnormal lymph node secondary follicle morphology Figure Label: MP:0002346 Species: Mus musculus  Data Points: 32  Description: "any structural anomaly of a lymph node primary follicle that has undergone antigenic challenge and is characterized by a ring of concentrically packed B lymphocytes surrounding a germinal center, which contains proliferating B cells, and a mantle area that contains nondividing B cells and some helper T cells with macrophages and follicular dendritic cells interspersed" [ISBN:0716749475] Available to: Everyone (Tier I)
	GS210580: GO:0002718 regulation of cytokine production involved in immune response Figure Label: GO:0002718 Species: Homo sapiens  Data Points: 39  Description: "Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response." [GOC:add] Available to: Everyone (Tier I)
	GS166250: MP:0008247 abnormal mononuclear cell morphology Figure Label: MP:0008247 Species: Mus musculus  Data Points: 1738  Description: "any structural anomaly of a leukocyte with a single non-segmented nucleus in the mature form" [CL:0000842] Available to: Everyone (Tier I)
	GS175806: HP:0001417 X-linked inheritance Figure Label: HP:0001417 Species: Homo sapiens  Data Points: 160  Description: "A mode of inheritance that is observed for traits related to a gene encoded on the X chromosome." [HPO:curators] Available to: Everyone (Tier I)
	GS199538: GO:0018193 peptidyl-amino acid modification Figure Label: GO:0018193 Species: Homo sapiens  Data Points: 637  Description: "The alteration of an amino acid residue in a peptide." [GOC:mah] Available to: Everyone (Tier I)
	GS182223: GO:0002366 leukocyte activation involved in immune response Figure Label: GO:0002366 Species: Mus musculus  Data Points: 140  Description: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] Available to: Everyone (Tier I)
	GS175786: HP:0001412 Enteroviral hepatitis Figure Label: HP:0001412 Species: Homo sapiens  Data Points: 1  Description: Enteroviral hepatitis Available to: Everyone (Tier I)
	GS163854: MP:0000549 absent limbs Figure Label: MP:0000549 Species: Mus musculus  Data Points: 24  Description: "missing extremities" [J:50768, J:51966] Available to: Everyone (Tier I)
	GS182234: GO:0036211 protein modification process Figure Label: GO:0036211 Species: Mus musculus  Data Points: 2223  Description: "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." [GOC:bf, GOC:jl] Available to: Everyone (Tier I)
	GS193015: GO:0003001 generation of a signal involved in cell-cell signaling Figure Label: GO:0003001 Species: Mus musculus  Data Points: 315  Description: "The cellular process that creates a physical entity or change in state, i.e. a signal, that originates in one cell and is used to transfer information to another cell. This process begins with the initial formation of the signal and ends with the mature form and placement of the signal." [GOC:dph] Available to: Everyone (Tier I)
	GS188506: GO:0010467 gene expression Figure Label: GO:0010467 Species: Mus musculus  Data Points: 3978  Description: "The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS196587: GO:0006468 protein phosphorylation Figure Label: GO:0006468 Species: Homo sapiens  Data Points: 1115  Description: "The process of introducing a phosphate group on to a protein." [GOC:hb] Available to: Everyone (Tier I)
	GS199214: GO:0034130 toll-like receptor 1 signaling pathway Figure Label: GO:0034130 Species: Homo sapiens  Data Points: 68  Description: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 1." [GOC:add, PMID:16551253, PMID:17328678] Available to: Everyone (Tier I)
	GS164534: MP:0002019 abnormal tumor incidence Figure Label: MP:0002019 Species: Mus musculus  Data Points: 1267  Description: "deviation from the expected number of abnormal growths in a specific population" [MGI:cwg] Available to: Everyone (Tier I)
	GS164799: MP:0008174 decreased follicular B cell number Figure Label: MP:0008174 Species: Mus musculus  Data Points: 82  Description: "reduced number of resting mature B cells with distinct phenotypic characteristics (CD23-positive, CD21-positive) found typically in the B cell follicle region of the spleen and lymph nodes" [CL:0000843, ISBN:0781735149, MGI:csmith] Available to: Everyone (Tier I)
	GS171146: HP:0009714 Abnormality of the epididymis Figure Label: HP:0009714 Species: Homo sapiens  Data Points: 5  Description: "An abnormality of the `epididymis` (FMA:18255)." [HPO:probinson] Available to: Everyone (Tier I)
	GS184026: GO:0009914 hormone transport Figure Label: GO:0009914 Species: Mus musculus  Data Points: 214  Description: "The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:tb] Available to: Everyone (Tier I)
	GS208012: GO:0044464 cell part Figure Label: GO:0044464 Species: Homo sapiens  Data Points: 14644  Description: "Any constituent part of a cell, the basic structural and functional unit of all organisms." [GOC:jl] Available to: Everyone (Tier I)
	GS201252: GO:0044425 membrane part Figure Label: GO:0044425 Species: Homo sapiens  Data Points: 6151  Description: "Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:jl] Available to: Everyone (Tier I)
	GS210212: GO:0005575 cellular_component Figure Label: GO:0005575 Species: Homo sapiens  Data Points: 17054  Description: "The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together." [GOC:go_curators] Available to: Everyone (Tier I)
	GS186430: GO:0007243 intracellular protein kinase cascade Figure Label: GO:0007243 Species: Mus musculus  Data Points: 782  Description: "A series of reactions in which a signal is passed on to downstream proteins within the cell by sequential protein phosphorylation and activation of the cascade components." [GOC:bf, GOC:jl, GOC:signaling] Available to: Everyone (Tier I)
	GS174081: HP:0004322 Short stature Figure Label: HP:0004322 Species: Homo sapiens  Data Points: 518  Description: "A height below that which is expected according to age and gender norms. Although there is no universally accepted definition of short stature, many refer to "short stature" as height more than 2 standard deviations below the mean for age and gender (or below the 3rd percentile for age and gender dependent norms)." [HPO:curators] Available to: Everyone (Tier I)
	GS195291: GO:0006355 regulation of transcription, DNA-dependent Figure Label: GO:0006355 Species: Homo sapiens  Data Points: 2875  Description: "Any process that modulates the frequency, rate or extent of cellular DNA-dependent transcription." [GOC:go_curators, GOC:txnOH] Available to: Everyone (Tier I)
	GS201239: GO:0046483 heterocycle metabolic process Figure Label: GO:0046483 Species: Homo sapiens  Data Points: 5369  Description: "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [CHEBI:5686, ISBN:0198506732] Available to: Everyone (Tier I)
	GS177334: GO:0016192 vesicle-mediated transport Figure Label: GO:0016192 Species: Mus musculus  Data Points: 790  Description: "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane." [GOC:ai, GOC:mah, ISBN:08789310662000] Available to: Everyone (Tier I)
	GS191400: GO:0010817 regulation of hormone levels Figure Label: GO:0010817 Species: Mus musculus  Data Points: 346  Description: "Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action." [GOC:BHF, GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS205369: GO:0010468 regulation of gene expression Figure Label: GO:0010468 Species: Homo sapiens  Data Points: 3344  Description: "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS192073: GO:1901576 organic substance biosynthetic process Figure Label: GO:1901576 Species: Mus musculus  Data Points: 4218  Description: "The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie] Available to: Everyone (Tier I)
	GS185796: GO:0023061 signal release Figure Label: GO:0023061 Species: Mus musculus  Data Points: 315  Description: "The process in which a signal is secreted or discharged into the extracellular medium from a cellular source." [GOC:mtg_signal] Available to: Everyone (Tier I)
	GS188399: GO:0044238 primary metabolic process Figure Label: GO:0044238 Species: Mus musculus  Data Points: 7644  Description: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] Available to: Everyone (Tier I)
	GS173020: HP:0000818 Abnormality of the endocrine system Figure Label: HP:0000818 Species: Homo sapiens  Data Points: 514  Description: "Ab abnormality of the `endocrine system` (FMA:9668)." [HPO:probinson] Available to: Everyone (Tier I)
	GS188762: GO:0009889 regulation of biosynthetic process Figure Label: GO:0009889 Species: Mus musculus  Data Points: 2984  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] Available to: Everyone (Tier I)
	GS206623: GO:0050794 regulation of cellular process Figure Label: GO:0050794 Species: Homo sapiens  Data Points: 7689  Description: "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators] Available to: Everyone (Tier I)
	GS197924: GO:0046649 lymphocyte activation Figure Label: GO:0046649 Species: Homo sapiens  Data Points: 464  Description: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735140] Available to: Everyone (Tier I)
	GS184435: GO:0046483 heterocycle metabolic process Figure Label: GO:0046483 Species: Mus musculus  Data Points: 4478  Description: "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [CHEBI:5686, ISBN:0198506732] Available to: Everyone (Tier I)
	GS171595: HP:0005406 Recurrent bacterial skin infections Figure Label: HP:0005406 Species: Homo sapiens  Data Points: 10  Description: "Increased susceptibility to bacterial infections of the skin, as manifested by recurrent episodes of infectious dermatitis." [HPO:probinson] Available to: Everyone (Tier I)
	GS169063: MP:0005432 abnormal pro-B cell morphology Figure Label: MP:0005432 Species: Mus musculus  Data Points: 120  Description: "any structural anomaly of the progenitor cells of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but are not yet fully committed to the B cell lineage until the expression of PAX5 occurs" [CL:0000826, ISBN:0781735149, MGI:csmith] Available to: Everyone (Tier I)
	GS168422: MP:0000716 abnormal immune system cell morphology Figure Label: MP:0000716 Species: Mus musculus  Data Points: 1927  Description: "any structural anomaly of immune cells" [MGI:cwg] Available to: Everyone (Tier I)
	GS163818: MP:0002722 abnormal immune system organ morphology Figure Label: MP:0002722 Species: Mus musculus  Data Points: 1419  Description: "any structural anomaly of lymphoid organs" [MGI:cwg] Available to: Everyone (Tier I)
	GS166570: MP:0000694 spleen hypoplasia Figure Label: MP:0000694 Species: Mus musculus  Data Points: 155  Description: "underdevelopment or reduced size, usually due to a reduced cell number, in the spleen" [J:43971] Available to: Everyone (Tier I)
	GS169284: MP:0005093 decreased B cell proliferation Figure Label: MP:0005093 Species: Mus musculus  Data Points: 112  Description: "absent or reduced expansion rate of the B cell population by cell division in response to stimuli" [MGI:csmith, MGI:cwg] Available to: Everyone (Tier I)
	GS200527: GO:0002721 regulation of B cell cytokine production Figure Label: GO:0002721 Species: Homo sapiens  Data Points: 1  Description: "Any process that modulates the frequency, rate, or extent of B cell cytokine production." [GOC:add] Available to: Everyone (Tier I)
	GS203402: GO:0007498 mesoderm development Figure Label: GO:0007498 Species: Homo sapiens  Data Points: 110  Description: "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS177623: GO:0002553 histamine secretion by mast cell Figure Label: GO:0002553 Species: Mus musculus  Data Points: 5  Description: "The regulated release of histamine by a mast cell or group of mast cells." [GOC:add, ISBN:0781735149] Available to: Everyone (Tier I)
	GS179580: GO:0036094 small molecule binding Figure Label: GO:0036094 Species: Mus musculus  Data Points: 2439  Description: "Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:pm] Available to: Everyone (Tier I)
	GS194038: GO:1901362 organic cyclic compound biosynthetic process Figure Label: GO:1901362 Species: Homo sapiens  Data Points: 3737  Description: "The chemical reactions and pathways resulting in the formation of organic cyclic compound." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS201792: GO:0032559 adenyl ribonucleotide binding Figure Label: GO:0032559 Species: Homo sapiens  Data Points: 1510  Description: "Interacting selectively and non-covalently with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] Available to: Everyone (Tier I)
	GS205144: GO:0048468 cell development Figure Label: GO:0048468 Species: Homo sapiens  Data Points: 1456  Description: "The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:go_curators] Available to: Everyone (Tier I)
	GS169130: MP:0002441 abnormal granulocyte morphology Figure Label: MP:0002441 Species: Mus musculus  Data Points: 440  Description: "any structural anomaly of leukocytes that have abundant granules in the cytoplasm, including basophils, neutrophils, and eosinophils" [MESH:A11.118.637.415, MGI:cwg] Available to: Everyone (Tier I)
	GS205623: GO:0009888 tissue development Figure Label: GO:0009888 Species: Homo sapiens  Data Points: 1439  Description: "The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure." [ISBN:0471245208] Available to: Everyone (Tier I)
	GS176101: HP:0000924 Abnormality of the skeletal system Figure Label: HP:0000924 Species: Homo sapiens  Data Points: 1210  Description: "An abnormality of the `skeletal system` (FMA:23881)." [HPO:probinson] Available to: Everyone (Tier I)
	GS172403: HP:0011873 Abnormal platelet count Figure Label: HP:0011873 Species: Homo sapiens  Data Points: 124  Description: "Abnormal number of platelets per volume of blood. In a healthy adult, a normal platelet count is between 150,000 and 450,000 per microliter of blood." [DDD:kfreson] Available to: Everyone (Tier I)
	GS184220: GO:0071702 organic substance transport Figure Label: GO:0071702 Species: Mus musculus  Data Points: 1686  Description: "The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon." [CHEBI:50860, GOC:mah] Available to: Everyone (Tier I)
	GS183803: GO:0044267 cellular protein metabolic process Figure Label: GO:0044267 Species: Mus musculus  Data Points: 2926  Description: "The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification." [GOC:jl] Available to: Everyone (Tier I)
	GS123718: Ethinyl Estradiol interacting genes (MeSH:D004997) in CTD Figure Label: D004997 [CTD] Species: Homo sapiens  Data Points: 4423  Description: Genes that interact with the MeSH term 'Ethinyl Estradiol' (D004997). Incorporates data from 226 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene. Available to: Everyone (Tier I)
	GS171791: HP:0000370 Abnormality of the middle ear Figure Label: HP:0000370 Species: Homo sapiens  Data Points: 220  Description: "An abnormality of the `middle ear` (FMA:56513)." [HPO:probinson] Available to: Everyone (Tier I)
	GS198022: GO:0002703 regulation of leukocyte mediated immunity Figure Label: GO:0002703 Species: Homo sapiens  Data Points: 95  Description: "Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] Available to: Everyone (Tier I)
	GS174385: HP:0002088 Abnormality of the lung Figure Label: HP:0002088 Species: Homo sapiens  Data Points: 545  Description: "An abnormality of the `lung` (FMA:7195)." [HPO:probinson] Available to: Everyone (Tier I)
	GS174500: HP:0000707 Abnormality of the nervous system Figure Label: HP:0000707 Species: Homo sapiens  Data Points: 1569  Description: "An abnormality of the `nervous system` (FMA:7157)." [HPO:probinson] Available to: Everyone (Tier I)
	GS177310: GO:1901360 organic cyclic compound metabolic process Figure Label: GO:1901360 Species: Mus musculus  Data Points: 4651  Description: "The chemical reactions and pathways involving organic cyclic compound." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS171998: HP:0001939 Abnormality of metabolism/homeostasis Figure Label: HP:0001939 Species: Homo sapiens  Data Points: 1228  Description: Abnormality of metabolism/homeostasis Available to: Everyone (Tier I)
	GS203755: GO:0016265 death Figure Label: GO:0016265 Species: Homo sapiens  Data Points: 1699  Description: "A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism." [GOC:mah, ISBN:0877797099] Available to: Everyone (Tier I)
	GS167020: MP:0003956 abnormal body size Figure Label: MP:0003956 Species: Mus musculus  Data Points: 3110  Description: "anomaly in the average body weight, height and/or length of an organism compared to controls" [MGI:csmith] Available to: Everyone (Tier I)
	GS164263: MP:0002083 premature death Figure Label: MP:0002083 Species: Mus musculus  Data Points: 1777  Description: "death after weaning age, but before the normal life span (Mus: after 3 weeks of age)" [MGI:csmith] Available to: Everyone (Tier I)
	GS169331: MP:0001663 abnormal digestive system physiology Figure Label: MP:0001663 Species: Mus musculus  Data Points: 692  Description: "any functional anomaly of the organ system that converts ingested food to nutrients and energy" [MGI:cwg] Available to: Everyone (Tier I)
	GS200016: GO:0001817 regulation of cytokine production Figure Label: GO:0001817 Species: Homo sapiens  Data Points: 378  Description: "Any process that modulates the frequency, rate, or extent of production of a cytokine." [GOC:add, ISBN:0781735149] Available to: Everyone (Tier I)
	GS162986: MP:0001802 arrested B cell differentiation Figure Label: MP:0001802 Species: Mus musculus  Data Points: 84  Description: "inability to produce mature B cells, and accumulation of B cell precursors" [J:52607] Available to: Everyone (Tier I)
	GS169535: MP:0005397 hematopoietic system phenotype Figure Label: MP:0005397 Species: Mus musculus  Data Points: 2821  Description: hematopoietic system phenotype Available to: Everyone (Tier I)
	GS210180: GO:0031326 regulation of cellular biosynthetic process Figure Label: GO:0031326 Species: Homo sapiens  Data Points: 3324  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] Available to: Everyone (Tier I)
	GS201488: GO:0021700 developmental maturation Figure Label: GO:0021700 Species: Homo sapiens  Data Points: 350  Description: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:mtg_15jun06] Available to: Everyone (Tier I)
	GS166038: MP:0005351 decreased susceptibility to autoimmune disorder Figure Label: MP:0005351 Species: Mus musculus  Data Points: 256  Description: "reduced likelihood that an organism will develop disease characterized by production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides" [MESH:C20.111, MGI:cwg] Available to: Everyone (Tier I)
	GS204096: GO:0030183 B cell differentiation Figure Label: GO:0030183 Species: Homo sapiens  Data Points: 75  Description: "The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity." [GO_REF:0000022, GOC:mah, GOC:mtg_15nov05] Available to: Everyone (Tier I)
	GS127019: 2-Naphthylamine interacting genes (MeSH:D015081) in CTD Figure Label: D015081 [CTD] Species: Homo sapiens  Data Points: 86  Description: Genes that interact with the MeSH term '2-Naphthylamine' (D015081). Incorporates data from 8 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene. Available to: Everyone (Tier I)
	GS177902: GO:0042802 identical protein binding Figure Label: GO:0042802 Species: Mus musculus  Data Points: 863  Description: "Interacting selectively and non-covalently with an identical protein or proteins." [GOC:jl] Available to: Everyone (Tier I)
	GS182834: GO:0005623 cell Figure Label: GO:0005623 Species: Mus musculus  Data Points: 13187  Description: "The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:go_curators] Available to: Everyone (Tier I)
	GS205622: GO:0009889 regulation of biosynthetic process Figure Label: GO:0009889 Species: Homo sapiens  Data Points: 3354  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] Available to: Everyone (Tier I)
	GS176087: HP:0006562 Viral hepatitis Figure Label: HP:0006562 Species: Homo sapiens  Data Points: 13  Description: "Inflammation of the liver due to infection with a virus." [HPO:probinson] Available to: Everyone (Tier I)
	GS191151: GO:0010556 regulation of macromolecule biosynthetic process Figure Label: GO:0010556 Species: Mus musculus  Data Points: 2835  Description: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS205511: GO:0001882 nucleoside binding Figure Label: GO:0001882 Species: Homo sapiens  Data Points: 1850  Description: "Interacting selectively and non-covalently with a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose." [GOC:hjd] Available to: Everyone (Tier I)
	GS136623: Stem cell proliferation 11 (Scpro11, Published QTL Chr X) Figure Label: QTL-Scpro11-Mouse-Chr X Species: Mus musculus  Data Points: 288  Description: QTL associated with Stem cell proliferation 11. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (132692552) Available to: Everyone (Tier I)
	GS169773: MP:0001845 abnormal inflammatory response Figure Label: MP:0001845 Species: Mus musculus  Data Points: 1503  Description: "aberrant reaction of the microcirculation characterized by movement of fluid and leukocytes from the blood into extravascular tissues" [ISBN:0-397-51047-0] Available to: Everyone (Tier I)
	GS189460: GO:0060255 regulation of macromolecule metabolic process Figure Label: GO:0060255 Species: Mus musculus  Data Points: 3757  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS126206: Nicotine interacting genes (MeSH:D009538) in CTD Figure Label: CTD Nicotine interacting genes Species: Homo sapiens  Data Points: 130  Description: Genes that interact with the MeSH term 'Nicotine' (D009538). Incorporates data from 83 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene. Available to: Everyone (Tier I)
	GS178448: GO:0005634 nucleus Figure Label: GO:0005634 Species: Mus musculus  Data Points: 5247  Description: "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] Available to: Everyone (Tier I)
	GS168845: MP:0002459 abnormal B cell physiology Figure Label: MP:0002459 Species: Mus musculus  Data Points: 731  Description: "any functional anomaly of lymphocytes that expresses membrane-bound antibody, and differentiate into antibody-secreting plasma cells and memory cells upon interaction with antigen; B cells are the primary lymphocyte responsible for humoral immunity, and are most effective against extracellular pathogens" [MGI:csmith, MGI:cwg] Available to: Everyone (Tier I)
	GS199635: GO:0005622 intracellular Figure Label: GO:0005622 Species: Homo sapiens  Data Points: 12561  Description: "The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS195206: GO:0002520 immune system development Figure Label: GO:0002520 Species: Homo sapiens  Data Points: 561  Description: "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:add, GOC:dph] Available to: Everyone (Tier I)
	GS167882: MP:0008496 decreased IgG2a level Figure Label: MP:0008496 Species: Mus musculus  Data Points: 93  Description: "less than normal immunoglobulin class G2a level" [MGI:tmeehan] Available to: Everyone (Tier I)
	GS180830: GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding Figure Label: GO:0005547 Species: Mus musculus  Data Points: 20  Description: "Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions." [GOC:bf, GOC:jl] Available to: Everyone (Tier I)
	GS207365: GO:0005829 cytosol Figure Label: GO:0005829 Species: Homo sapiens  Data Points: 2368  Description: "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes." [GOC:hgd, GOC:jl] Available to: Everyone (Tier I)
	GS178444: GO:0046777 protein autophosphorylation Figure Label: GO:0046777 Species: Mus musculus  Data Points: 184  Description: "The phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS188798: GO:0042493 response to drug Figure Label: GO:0042493 Species: Mus musculus  Data Points: 197  Description: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease." [GOC:jl] Available to: Everyone (Tier I)
	GS208061: GO:0010556 regulation of macromolecule biosynthetic process Figure Label: GO:0010556 Species: Homo sapiens  Data Points: 3199  Description: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS178537: GO:0006355 regulation of transcription, DNA-dependent Figure Label: GO:0006355 Species: Mus musculus  Data Points: 2536  Description: "Any process that modulates the frequency, rate or extent of cellular DNA-dependent transcription." [GOC:go_curators, GOC:txnOH] Available to: Everyone (Tier I)
	GS205483: GO:0002221 pattern recognition receptor signaling pathway Figure Label: GO:0002221 Species: Homo sapiens  Data Points: 127  Description: "Any series of molecular signals generated as a consequence of binding to a cell surface or intracellular pattern recognition receptor (PRR). Such receptors bind for molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens." [GOC:add, ISBN:0781735149, PMID:15199967] Available to: Everyone (Tier I)
	GS196943: GO:0008152 metabolic process Figure Label: GO:0008152 Species: Homo sapiens  Data Points: 9471  Description: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684] Available to: Everyone (Tier I)
	GS163077: MP:0010274 increased organ/body region tumor incidence Figure Label: MP:0010274 Species: Mus musculus  Data Points: 1020  Description: "greater than the expected number of tumors originating in a specific body region or organ in a given population in a given time period" [MGI:csmith] Available to: Everyone (Tier I)
	GS180305: GO:0016310 phosphorylation Figure Label: GO:0016310 Species: Mus musculus  Data Points: 1451  Description: "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS187146: GO:0044700 single organism signaling Figure Label: GO:0044700 Species: Mus musculus  Data Points: 5111  Description: "A signaling process occurring within a single organism." [GOC:jl] Available to: Everyone (Tier I)
	GS209550: GO:0031982 vesicle Figure Label: GO:0031982 Species: Homo sapiens  Data Points: 970  Description: "Any small, fluid-filled, spherical organelle enclosed by membrane or protein." [GOC:mah, GOC:pz] Available to: Everyone (Tier I)
	GS174554: HP:0002383 Encephalitis Figure Label: HP:0002383 Species: Homo sapiens  Data Points: 12  Description: Encephalitis Available to: Everyone (Tier I)
	GS173537: HP:0001872 Abnormality of thrombocytes Figure Label: HP:0001872 Species: Homo sapiens  Data Points: 148  Description: "An abnormality of `platelets` (CL:0000233)." [HPO:probinson] Available to: Everyone (Tier I)
	GS169734: MP:0002460 decreased immunoglobulin level Figure Label: MP:0002460 Species: Mus musculus  Data Points: 345  Description: "less than normal immunoglobulin level" [MGI:cwg] Available to: Everyone (Tier I)
	GS165244: MP:0010771 integument phenotype Figure Label: MP:0010771 Species: Mus musculus  Data Points: 2199  Description: "the observable morphological and physiological characteristics of the skin and its associated structures, such as the hair, nails, sweat glands, sebaceous glands and other secretory glands" [MGI:csmith] Available to: Everyone (Tier I)
	GS174075: HP:0009121 Abnormal axial skeleton morphology Figure Label: HP:0009121 Species: Homo sapiens  Data Points: 941  Description: "An abnormality of the axial skeleton, which comprises the skull, the vertebral column, the ribs and the sternum." [HPO:probinson] Available to: Everyone (Tier I)
	GS196941: GO:0008150 biological_process Figure Label: GO:0008150 Species: Homo sapiens  Data Points: 14623  Description: "Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end." [GOC:go_curators, GOC:isa_complete] Available to: Everyone (Tier I)
	GS164673: MP:0010296 increased hemolymphoid system tumor incidence Figure Label: MP:0010296 Species: Mus musculus  Data Points: 401  Description: "greater than the expected number of tumors originating in the hemolymphoid system in a given population in a given time period" [MGI:csmith] Available to: Everyone (Tier I)
	GS199634: GO:0005623 cell Figure Label: GO:0005623 Species: Homo sapiens  Data Points: 14645  Description: "The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:go_curators] Available to: Everyone (Tier I)
	GS207176: GO:0050865 regulation of cell activation Figure Label: GO:0050865 Species: Homo sapiens  Data Points: 353  Description: "Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:ai] Available to: Everyone (Tier I)
	GS164136: MP:0000001 mammalian phenotype Figure Label: MP:0000001 Species: Mus musculus  Data Points: 14488  Description: "the observable morphological, physiological, behavioral and other characteristics of mammalian organisms that are manifested through development and lifespan" [MGI:csmith] Available to: Everyone (Tier I)
	GS173994: HP:0000509 Conjunctivitis Figure Label: HP:0000509 Species: Homo sapiens  Data Points: 30  Description: "Inflammation of the `conjunctiva` (FMA:59011)." [HPO:probinson] Available to: Everyone (Tier I)
	GS190893: GO:0030154 cell differentiation Figure Label: GO:0030154 Species: Mus musculus  Data Points: 2538  Description: "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS169908: MP:0001601 abnormal myelopoiesis Figure Label: MP:0001601 Species: Mus musculus  Data Points: 133  Description: "anomaly in the process of, or atypical formation of myeloid cells from the pluripotent hematopoietic stem cells in the bone marrow from myeloid stem cells, including the production of leukocytes in blood, such as monocytes and granulocytes and precursor cells for macrophage and dendritic cells found in the lymphoid tissue" [MESH:G04.335.151.825.597.750] Available to: Everyone (Tier I)
	GS166564: MP:0000692 small spleen Figure Label: MP:0000692 Species: Mus musculus  Data Points: 295  Description: "decreased spleen size" [MGI:cwg] Available to: Everyone (Tier I)
	GS197009: GO:0005886 plasma membrane Figure Label: GO:0005886 Species: Homo sapiens  Data Points: 4283  Description: "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363] Available to: Everyone (Tier I)
	GS187045: GO:0016070 RNA metabolic process Figure Label: GO:0016070 Species: Mus musculus  Data Points: 3136  Description: "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS198019: GO:0002706 regulation of lymphocyte mediated immunity Figure Label: GO:0002706 Species: Homo sapiens  Data Points: 75  Description: "Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] Available to: Everyone (Tier I)
	GS172617: HP:0004313 Hypogammaglobulinemia Figure Label: HP:0004313 Species: Homo sapiens  Data Points: 64  Description: "An abnormally decreased level of immunoglobulin in blood." [HPO:probinson] Available to: Everyone (Tier I)
	GS175814: HP:0011024 Abnormality of the gastrointestinal tract Figure Label: HP:0011024 Species: Homo sapiens  Data Points: 525  Description: "An abnormality of the `gastrointestinal tract` (FMA:71132)." [HPO:probinson] Available to: Everyone (Tier I)
	GS204007: GO:0044700 single organism signaling Figure Label: GO:0044700 Species: Homo sapiens  Data Points: 4593  Description: "A signaling process occurring within a single organism." [GOC:jl] Available to: Everyone (Tier I)
	GS210182: GO:0031323 regulation of cellular metabolic process Figure Label: GO:0031323 Species: Homo sapiens  Data Points: 4377  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] Available to: Everyone (Tier I)
	GS163026: MP:0000221 decreased leukocyte cell number Figure Label: MP:0000221 Species: Mus musculus  Data Points: 1098  Description: "reduction in the number of nucleated cells of the myeloid or lymphoid lineages, found in blood or other tissue" [CL:0000738, MESH:A11.118.637] Available to: Everyone (Tier I)
	GS196282: GO:0012501 programmed cell death Figure Label: GO:0012501 Species: Homo sapiens  Data Points: 1539  Description: "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell." [GOC:lr, GOC:mtg_apoptosis] Available to: Everyone (Tier I)
	GS201431: GO:0005515 protein binding Figure Label: GO:0005515 Species: Homo sapiens  Data Points: 7336  Description: "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] Available to: Everyone (Tier I)
	GS163817: MP:0002359 abnormal spleen germinal center morphology Figure Label: MP:0002359 Species: Mus musculus  Data Points: 123  Description: "any structural anomaly of the area of the spleen secondary B follicle where rapid B-cell proliferation, somatic hypermutation, and selection for antigen binding occurs" [PMID:17495967] Available to: Everyone (Tier I)
	GS176613: HP:0000271 Abnormality of the face Figure Label: HP:0000271 Species: Homo sapiens  Data Points: 1103  Description: "An abnormality of the `face` (FMA:24728)." [HPO:probinson] Available to: Everyone (Tier I)
	GS165615: MP:0002123 abnormal hematopoiesis Figure Label: MP:0002123 Species: Mus musculus  Data Points: 2404  Description: "abnormal development of blood cells in the fetal and adult organism; in the fetus cells develop in the aorta, genital ridge and mesonephros region and later in the liver; in adults cells normally develop in the bone marrow and lymphatic tissues" [MGI:csmith] Available to: Everyone (Tier I)
	GS188061: GO:0016772 transferase activity, transferring phosphorus-containing groups Figure Label: GO:0016772 Species: Mus musculus  Data Points: 905  Description: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] Available to: Everyone (Tier I)
	GS196933: GO:0065009 regulation of molecular function Figure Label: GO:0065009 Species: Homo sapiens  Data Points: 1799  Description: "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GOC:isa_complete] Available to: Everyone (Tier I)
	GS203649: GO:0030554 adenyl nucleotide binding Figure Label: GO:0030554 Species: Homo sapiens  Data Points: 1514  Description: "Interacting selectively and non-covalently with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS206192: GO:0048583 regulation of response to stimulus Figure Label: GO:0048583 Species: Homo sapiens  Data Points: 2335  Description: "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] Available to: Everyone (Tier I)
	GS176735: HP:0010929 Abnormality of cation homeostasis Figure Label: HP:0010929 Species: Homo sapiens  Data Points: 103  Description: "An abnormality of `cation homeostasis` (GO:0055080)." [HPO:probinson] Available to: Everyone (Tier I)
	GS209411: GO:0048869 cellular developmental process Figure Label: GO:0048869 Species: Homo sapiens  Data Points: 2824  Description: "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." [GOC:isa_complete] Available to: Everyone (Tier I)
	GS190027: GO:0006952 defense response Figure Label: GO:0006952 Species: Mus musculus  Data Points: 802  Description: "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:go_curators] Available to: Everyone (Tier I)
	GS172887: HP:0100533 Inflammatory abnormality of the eye Figure Label: HP:0100533 Species: Homo sapiens  Data Points: 80  Description: "Inflammation of the eye, parts of the eye or the periorbital region." [HPO:sdoelken] Available to: Everyone (Tier I)
	GS187160: GO:0044707 single-multicellular organism process Figure Label: GO:0044707 Species: Mus musculus  Data Points: 5879  Description: "A biological process occurring within a single, multicellular organism." [GOC:jl] Available to: Everyone (Tier I)
	GS163314: MP:0005005 abnormal self tolerance Figure Label: MP:0005005 Species: Mus musculus  Data Points: 628  Description: "a defect in the normal lack of response to autologous (self) antigens" [ISBN:0-8153-1691-7, MGI:cwg] Available to: Everyone (Tier I)
	GS177761: GO:0044271 cellular nitrogen compound biosynthetic process Figure Label: GO:0044271 Species: Mus musculus  Data Points: 2981  Description: "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732] Available to: Everyone (Tier I)
	GS163851: MP:0001545 abnormal hematopoietic system physiology Figure Label: MP:0001545 Species: Mus musculus  Data Points: 412  Description: "any functional anomaly of the fluid and/or its suspended elements that circulate(s) through the heart, arteries, capillaries, and veins" [ISBN:0-683-40008-8] Available to: Everyone (Tier I)
	GS175016: HP:0001626 Abnormality of the cardiovascular system Figure Label: HP:0001626 Species: Homo sapiens  Data Points: 889  Description: "Any abnormality of the `cardiovascular system` (FMA:7161)." [HPO:probinson] Available to: Everyone (Tier I)
	GS203371: GO:0002684 positive regulation of immune system process Figure Label: GO:0002684 Species: Homo sapiens  Data Points: 551  Description: "Any process that activates or increases the frequency, rate, or extent of an immune system process." [GOC:add] Available to: Everyone (Tier I)
	GS185925: GO:0015893 drug transport Figure Label: GO:0015893 Species: Mus musculus  Data Points: 40  Description: "The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] Available to: Everyone (Tier I)
	GS166066: MP:0009334 abnormal splenocyte proliferation Figure Label: MP:0009334 Species: Mus musculus  Data Points: 46  Description: "anomaly in the ability of a splenocyte cell population to undergo expansion by cell division" [MGI:csmith] Available to: Everyone (Tier I)
	GS197355: GO:0050778 positive regulation of immune response Figure Label: GO:0050778 Species: Homo sapiens  Data Points: 373  Description: "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] Available to: Everyone (Tier I)
	GS168551: MP:0002429 abnormal blood cell morphology/development Figure Label: MP:0002429 Species: Mus musculus  Data Points: 2419  Description: "any structural anomaly of any of the cells found in the blood or hematopoietic organ" [MGI:cwg] Available to: Everyone (Tier I)
	GS186881: GO:0002532 production of molecular mediator involved in inflammatory response Figure Label: GO:0002532 Species: Mus musculus  Data Points: 30  Description: "The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:dph, GOC:tb, ISBN:0781735149] Available to: Everyone (Tier I)
	GS166518: MP:0008190 decreased transitional stage B cell number Figure Label: MP:0008190 Species: Mus musculus  Data Points: 58  Description: "reduced number of immature B cells of an intermediate stage between the pre-B cell stage and the mature naive stage; transitional B cells express surface immunoglobulin, and are subject to the process of B cell selection" [CL:0000818, ISBN:0781735149, MGI:csmith] Available to: Everyone (Tier I)
	GS169906: MP:0001602 impaired myelopoiesis Figure Label: MP:0001602 Species: Mus musculus  Data Points: 15  Description: "atypical process of bone marrow cell formation and/or the formation of bone marrow-derived blood cells with the result of fewer of these cells being formed" [ISBN:0-683-40008-8, MGI:tc] Available to: Everyone (Tier I)
	GS194685: GO:0050853 B cell receptor signaling pathway Figure Label: GO:0050853 Species: Homo sapiens  Data Points: 30  Description: "A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell." [GOC:add] Available to: Everyone (Tier I)
	GS206273: GO:0002755 MyD88-dependent toll-like receptor signaling pathway Figure Label: GO:0002755 Species: Homo sapiens  Data Points: 76  Description: "Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GOC:add, ISBN:0781735149, PMID:12467241, PMID:12524386, PMID:12855817, PMID:15585605, PMID:15728447] Available to: Everyone (Tier I)
	GS168560: MP:0002420 abnormal adaptive immunity Figure Label: MP:0002420 Species: Mus musculus  Data Points: 1610  Description: "anomaly in the function of the response of antigen-specific lymphocytes to antigen, including the development of immunological memory" [ISBN:0-8153-1691-7, MGI:cwg] Available to: Everyone (Tier I)
	GS209564: GO:0043231 intracellular membrane-bounded organelle Figure Label: GO:0043231 Species: Homo sapiens  Data Points: 9574  Description: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS169846: MP:0009788 increased susceptibility to bacterial infection induced morbidity/mortality Figure Label: MP:0009788 Species: Mus musculus  Data Points: 63  Description: "increased likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria" [MGI:smb] Available to: Everyone (Tier I)
	GS172542: HP:0000830 Anterior hypopituitarism Figure Label: HP:0000830 Species: Homo sapiens  Data Points: 47  Description: "A condition of reduced function of the pituitary gland characterized by decreased secretion of one or more of the pituitary hormones growth hormone, thyroid-stimulating hormone, adrenocorticotropic hormone, prolactin, luteinizing hormone, and follicle-stimulating hormone." [HPO:probinson] Available to: Everyone (Tier I)
	GS202080: GO:0051252 regulation of RNA metabolic process Figure Label: GO:0051252 Species: Homo sapiens  Data Points: 2957  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] Available to: Everyone (Tier I)
	GS208051: GO:0002521 leukocyte differentiation Figure Label: GO:0002521 Species: Homo sapiens  Data Points: 325  Description: "The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:add, PMID:16551264] Available to: Everyone (Tier I)
	GS171274: HP:0100543 Cognitive impairment Figure Label: HP:0100543 Species: Homo sapiens  Data Points: 1060  Description: "Abnormality in the process of thought including the ability to process information." [HPO:sdoelken] Available to: Everyone (Tier I)
	GS207675: GO:0002696 positive regulation of leukocyte activation Figure Label: GO:0002696 Species: Homo sapiens  Data Points: 233  Description: "Any process that activates or increases the frequency, rate, or extent of leukocyte activation." [GOC:add] Available to: Everyone (Tier I)
	GS169827: MP:0005387 immune system phenotype Figure Label: MP:0005387 Species: Mus musculus  Data Points: 3815  Description: immune system phenotype Available to: Everyone (Tier I)
	GS175981: HP:0000163 Abnormality of the oral cavity Figure Label: HP:0000163 Species: Homo sapiens  Data Points: 702  Description: "Abnormality of the `oral cavity` (FMA:20292), i.e., the opening or hollow part of the mouth." [HPO:curators] Available to: Everyone (Tier I)
	GS184976: GO:0032559 adenyl ribonucleotide binding Figure Label: GO:0032559 Species: Mus musculus  Data Points: 1444  Description: "Interacting selectively and non-covalently with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] Available to: Everyone (Tier I)
	GS186899: GO:0016265 death Figure Label: GO:0016265 Species: Mus musculus  Data Points: 1465  Description: "A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism." [GOC:mah, ISBN:0877797099] Available to: Everyone (Tier I)
	GS173262: HP:0000864 Abnormality of the hypothalamus-pituitary axis Figure Label: HP:0000864 Species: Homo sapiens  Data Points: 114  Description: "Abnormality of the pituitary gland (also known as hypophysis), which is an endocrine gland that protrudes from the bottom of the hypothalamus at the base of the brain. The pituitary gland secretes the hormones ACTH, TSH, PRL, GH, endorphins, FSH, LH, oxytocin, and antidiuretic hormone. The secretion of hormones from the anterior pituitary is under the strict control of hypothalamic hormones, and the posterior pituitary is essentially an extension of the hypothalamus, so that hypothalamus and pituitary gland may be regarded as a functional unit." [DDD:spark] Available to: Everyone (Tier I)
	GS171848: HP:0000598 Abnormality of the ear Figure Label: HP:0000598 Species: Homo sapiens  Data Points: 842  Description: "An abnormality of the `ear` (FMA:52780)." [HPO:probinson] Available to: Everyone (Tier I)
	GS163143: MP:0009548 abnormal platelet aggregation Figure Label: MP:0009548 Species: Mus musculus  Data Points: 68  Description: "any functional anomaly in the adhesion of one platelet to one or more other platelets via adhesion molecules" [GO:0070527] Available to: Everyone (Tier I)
	GS163297: MP:0000217 abnormal leukocyte cell number Figure Label: MP:0000217 Species: Mus musculus  Data Points: 1521  Description: "any anomaly in the number of nucleated cells of the myeloid or lymphoid lineages, found in blood or other tissue" [CL:0000738, MESH:A11.118.637] Available to: Everyone (Tier I)
	GS175015: HP:0001627 Abnormality of the heart Figure Label: HP:0001627 Species: Homo sapiens  Data Points: 545  Description: "An abnormality of the `heart` (FMA:7088)." [HPO:probinson] Available to: Everyone (Tier I)
	GS187876: GO:0045121 membrane raft Figure Label: GO:0045121 Species: Mus musculus  Data Points: 218  Description: "Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions." [PMID:16645198] Available to: Everyone (Tier I)
	GS204021: GO:0044707 single-multicellular organism process Figure Label: GO:0044707 Species: Homo sapiens  Data Points: 5605  Description: "A biological process occurring within a single, multicellular organism." [GOC:jl] Available to: Everyone (Tier I)
	GS205047: GO:0006807 nitrogen compound metabolic process Figure Label: GO:0006807 Species: Homo sapiens  Data Points: 5962  Description: "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium." [CHEBI:51143, GOC:go_curators, GOC:jl, ISBN:0198506732] Available to: Everyone (Tier I)
	GS184629: GO:0005515 protein binding Figure Label: GO:0005515 Species: Mus musculus  Data Points: 6204  Description: "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] Available to: Everyone (Tier I)
	GS208665: GO:0008289 lipid binding Figure Label: GO:0008289 Species: Homo sapiens  Data Points: 738  Description: "Interacting selectively and non-covalently with a lipid." [GOC:ai] Available to: Everyone (Tier I)
	GS176186: HP:0000079 Abnormality of the urinary system Figure Label: HP:0000079 Species: Homo sapiens  Data Points: 737  Description: "An abnormality of the `urinary system` (FMA:7159)." [HPO:probinson] Available to: Everyone (Tier I)
	GS166201: MP:0008186 increased pro-B cell number Figure Label: MP:0008186 Species: Mus musculus  Data Points: 50  Description: "greater number of the progenitor cells of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but are not yet fully committed to the B cell lineage until the expression of PAX5 occurs" [CL:0000826, ISBN:0781735149, MGI:csmith] Available to: Everyone (Tier I)
	GS177843: GO:0002376 immune system process Figure Label: GO:0002376 Species: Mus musculus  Data Points: 1350  Description: "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05] Available to: Everyone (Tier I)
	GS165258: MP:0008537 increased susceptibility to induced colitis Figure Label: MP:0008537 Species: Mus musculus  Data Points: 78  Description: "increased severity or induction threshold of colitis upon treatment of an organism with intestinal inflammation agents such as dextran sodium sulfate (DSS)" [MGI:csmith] Available to: Everyone (Tier I)
	GS192539: GO:0006955 immune response Figure Label: GO:0006955 Species: Mus musculus  Data Points: 656  Description: "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05] Available to: Everyone (Tier I)
	GS163142: MP:0009549 decreased platelet aggregation Figure Label: MP:0009549 Species: Mus musculus  Data Points: 53  Description: "decrease in the ability of one platelet to one or more other platelets via adhesion molecules" [GO:0070527] Available to: Everyone (Tier I)
	GS168118: MP:0001191 abnormal skin condition Figure Label: MP:0001191 Species: Mus musculus  Data Points: 428  Description: "any anomaly in the state or quality of the skin" [MGI:cwg] Available to: Everyone (Tier I)
	GS197139: GO:0002429 immune response-activating cell surface receptor signaling pathway Figure Label: GO:0002429 Species: Homo sapiens  Data Points: 131  Description: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a cell capable of activating or perpetuating an immune response." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS194645: GO:0042802 identical protein binding Figure Label: GO:0042802 Species: Homo sapiens  Data Points: 858  Description: "Interacting selectively and non-covalently with an identical protein or proteins." [GOC:jl] Available to: Everyone (Tier I)
	GS172024: HP:0001369 Arthritis Figure Label: HP:0001369 Species: Homo sapiens  Data Points: 83  Description: "Inflammation of a joint." [HPO:probinson] Available to: Everyone (Tier I)
	GS198025: GO:0002700 regulation of production of molecular mediator of immune response Figure Label: GO:0002700 Species: Homo sapiens  Data Points: 65  Description: "Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] Available to: Everyone (Tier I)
	GS179211: GO:0007154 cell communication Figure Label: GO:0007154 Species: Mus musculus  Data Points: 5221  Description: "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:mah] Available to: Everyone (Tier I)
	GS171067: HP:0002664 Neoplasm Figure Label: HP:0002664 Species: Homo sapiens  Data Points: 397  Description: "An organ or organ-system abnormality that consists of uncontrolled autonomous cell-proliferation which can occur in any part of the body as a benign or malignant `neoplasm` (MPATH:218) (tumour)." [HPO:probinson] Available to: Everyone (Tier I)
	GS173327: HP:0005368 Abnormality of humoral immunity Figure Label: HP:0005368 Species: Homo sapiens  Data Points: 95  Description: "An abnormality of the humoral immune system, which comprises antibodies produced by B cells as well as the complement system." [HPO:probinson] Available to: Everyone (Tier I)
	GS188465: GO:0031410 cytoplasmic vesicle Figure Label: GO:0031410 Species: Mus musculus  Data Points: 787  Description: "A vesicle formed of membrane or protein, found in the cytoplasm of a cell." [GOC:mah] Available to: Everyone (Tier I)
	GS192265: GO:0007165 signal transduction Figure Label: GO:0007165 Species: Mus musculus  Data Points: 4725  Description: "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11] Available to: Everyone (Tier I)
	GS166064: MP:0009336 increased splenocyte proliferation Figure Label: MP:0009336 Species: Mus musculus  Data Points: 21  Description: "increase in the expansion rate of a splenocyte cell population by cell division" [MGI:csmith] Available to: Everyone (Tier I)
	GS180152: GO:0065007 biological regulation Figure Label: GO:0065007 Species: Mus musculus  Data Points: 9323  Description: "Any process that modulates a measurable attribute of any biological process, quality or function." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] Available to: Everyone (Tier I)
	GS185881: GO:0035639 purine ribonucleoside triphosphate binding Figure Label: GO:0035639 Species: Mus musculus  Data Points: 1724  Description: "Interacting selectively and non-covalently with a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar." [CHEBI:26398, GOC:BHF, GOC:ebc, ISBN:0198506732] Available to: Everyone (Tier I)
	GS165536: MP:0005371 limbs/digits/tail phenotype Figure Label: MP:0005371 Species: Mus musculus  Data Points: 1211  Description: limbs/digits/tail phenotype Available to: Everyone (Tier I)
	GS203303: GO:0045579 positive regulation of B cell differentiation Figure Label: GO:0045579 Species: Homo sapiens  Data Points: 10  Description: "Any process that activates or increases the frequency, rate or extent of B cell differentiation." [GOC:go_curators] Available to: Everyone (Tier I)
	GS163640: MP:0009787 increased susceptibility to infection induced morbidity/mortality Figure Label: MP:0009787 Species: Mus musculus  Data Points: 96  Description: "increased likelihood that an organism will display the expected moribund state caused by a pathogenic invasion or from components of or toxins produced by pathogens" [MGI:smb] Available to: Everyone (Tier I)
	GS165397: MP:0001265 decreased body size Figure Label: MP:0001265 Species: Mus musculus  Data Points: 2606  Description: "smaller than average body weight, height and/or length of an organism compared to controls" [ISBN:0-683-40008-8, PMID:7854452] Available to: Everyone (Tier I)
	GS170601: MP:0005621 abnormal cell physiology Figure Label: MP:0005621 Species: Mus musculus  Data Points: 3494  Description: "any functional anomaly of the vital processes of the cell" [ISBN:0-683-40008-8, MGI:hdene] Available to: Everyone (Tier I)
	GS179464: GO:0001821 histamine secretion Figure Label: GO:0001821 Species: Mus musculus  Data Points: 10  Description: "The regulated release of histamine by a cell or group of cells. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems." [GOC:mah, ISBN:0198506732, ISBN:0781735149] Available to: Everyone (Tier I)
	GS169485: MP:0000726 absent lymphocyte Figure Label: MP:0000726 Species: Mus musculus  Data Points: 160  Description: "absence of the cells involved in adaptive immune reactions of the body in most inflammatory and autoimmune diseases, including B cells, T cells and natural killer cells" [MGI:csmith, MGI:cwg] Available to: Everyone (Tier I)
	GS171789: HP:0001392 Abnormality of the liver Figure Label: HP:0001392 Species: Homo sapiens  Data Points: 487  Description: "An abnormality of the `liver` (FMA:7197)." [HPO:probinson] Available to: Everyone (Tier I)
	GS173267: HP:0004432 Agammaglobulinemia Figure Label: HP:0004432 Species: Homo sapiens  Data Points: 11  Description: "Absence or extremely low level of generally all classes of gamma-globulin in the blood." [HPO:probinson] Available to: Everyone (Tier I)
	GS189544: GO:0002448 mast cell mediated immunity Figure Label: GO:0002448 Species: Mus musculus  Data Points: 27  Description: "Any process involved in the carrying out of an immune response by a mast cell." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS187293: GO:0009611 response to wounding Figure Label: GO:0009611 Species: Mus musculus  Data Points: 612  Description: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism." [GOC:go_curators] Available to: Everyone (Tier I)
	GS194284: GO:0048534 hematopoietic or lymphoid organ development Figure Label: GO:0048534 Species: Homo sapiens  Data Points: 531  Description: "The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation." [GOC:add, GOC:rl, ISBN:0781735149] Available to: Everyone (Tier I)
	GS172030: HP:0000365 Hearing impairment Figure Label: HP:0000365 Species: Homo sapiens  Data Points: 578  Description: "A `decreased magnitude` (PATO:0002018) of the `sensory perception of sound` (GO:0007605)." [HPO:probinson] Available to: Everyone (Tier I)
	GS202716: GO:0035639 purine ribonucleoside triphosphate binding Figure Label: GO:0035639 Species: Homo sapiens  Data Points: 1827  Description: "Interacting selectively and non-covalently with a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar." [CHEBI:26398, GOC:BHF, GOC:ebc, ISBN:0198506732] Available to: Everyone (Tier I)
	GS172021: HP:0001367 Abnormal joint morphology Figure Label: HP:0001367 Species: Homo sapiens  Data Points: 601  Description: "An abnormal structure or form of the `joints` (FMA:73023), i.e., one or more of the articulations where two bones join." [HPO:probinson] Available to: Everyone (Tier I)
	GS173423: HP:0004429 Recurrent viral infections Figure Label: HP:0004429 Species: Homo sapiens  Data Points: 15  Description: "Increased susceptibility to viral infections, as manifested by recurrent episodes of viral infection." [HPO:probinson] Available to: Everyone (Tier I)
	GS196806: GO:0032502 developmental process Figure Label: GO:0032502 Species: Homo sapiens  Data Points: 4567  Description: "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." [GOC:isa_complete] Available to: Everyone (Tier I)
	GS206618: GO:0050793 regulation of developmental process Figure Label: GO:0050793 Species: Homo sapiens  Data Points: 1434  Description: "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:go_curators] Available to: Everyone (Tier I)
	GS163642: MP:0009785 altered susceptibility to infection induced morbidity/mortality Figure Label: MP:0009785 Species: Mus musculus  Data Points: 135  Description: "differences from the expected moribund state caused by a pathogenic invasion or from components of or toxins produced by pathogens" [MGI:smb] Available to: Everyone (Tier I)
	GS166215: MP:0008188 abnormal transitional stage B cell morphology Figure Label: MP:0008188 Species: Mus musculus  Data Points: 81  Description: "any structural anomaly of an immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage; transitional B cells express surface immunoglobulin, and are subject to the process of B cell selection" [CL:0000818, ISBN:0781735149, MGI:csmith] Available to: Everyone (Tier I)
	GS189549: GO:0002443 leukocyte mediated immunity Figure Label: GO:0002443 Species: Mus musculus  Data Points: 207  Description: "Any process involved in the carrying out of an immune response by a leukocyte." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS170965: HP:0000153 Abnormality of the mouth Figure Label: HP:0000153 Species: Homo sapiens  Data Points: 808  Description: "An abnormality of the `mouth` (FMA:49184)." [HPO:probinson] Available to: Everyone (Tier I)
	GS203594: GO:0043226 organelle Figure Label: GO:0043226 Species: Homo sapiens  Data Points: 10639  Description: "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS200432: GO:0002682 regulation of immune system process Figure Label: GO:0002682 Species: Homo sapiens  Data Points: 865  Description: "Any process that modulates the frequency, rate, or extent of an immune system process." [GOC:add] Available to: Everyone (Tier I)
	GS205364: GO:0010467 gene expression Figure Label: GO:0010467 Species: Homo sapiens  Data Points: 4713  Description: "The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS208734: GO:0016740 transferase activity Figure Label: GO:0016740 Species: Homo sapiens  Data Points: 1736  Description: "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS194172: GO:0006915 apoptotic process Figure Label: GO:0006915 Species: Homo sapiens  Data Points: 1522  Description: "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathways) which typically lead to rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. The process ends when the cell has died. The process is divided into a signaling pathway phase and into an execution phase, which is triggered by the former." [GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263] Available to: Everyone (Tier I)
	GS200446: GO:0017076 purine nucleotide binding Figure Label: GO:0017076 Species: Homo sapiens  Data Points: 1869  Description: "Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate." [GOC:ai] Available to: Everyone (Tier I)
	GS167719: MP:0002816 colitis Figure Label: MP:0002816 Species: Mus musculus  Data Points: 160  Description: "local accumulation of fluid, plasma proteins, and leukocytes in the colon region of the large intestine" [ISBN:0-683-40008-8] Available to: Everyone (Tier I)
	GS178744: GO:0007249 I-kappaB kinase/NF-kappaB cascade Figure Label: GO:0007249 Species: Mus musculus  Data Points: 167  Description: "The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription." [GOC:bf, GOC:jl, PMID:12773372, Reactome:REACT_13696.1] Available to: Everyone (Tier I)
	GS210002: GO:0044444 cytoplasmic part Figure Label: GO:0044444 Species: Homo sapiens  Data Points: 6769  Description: "Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GOC:jl] Available to: Everyone (Tier I)
	GS171168: HP:0000234 Abnormality of the head Figure Label: HP:0000234 Species: Homo sapiens  Data Points: 1208  Description: "An abnormality of the `head` (FMA:7154)." [HPO:probinson] Available to: Everyone (Tier I)
	GS179822: GO:0006468 protein phosphorylation Figure Label: GO:0006468 Species: Mus musculus  Data Points: 1172  Description: "The process of introducing a phosphate group on to a protein." [GOC:hb] Available to: Everyone (Tier I)
	GS164022: MP:0008246 abnormal leukocyte morphology Figure Label: MP:0008246 Species: Mus musculus  Data Points: 1914  Description: "any structural anomaly of nucleated cells of the myeloid or lymphoid lineages, found in blood or other tissue" [CL:0000738, MESH:A11.118.637] Available to: Everyone (Tier I)
	GS175530: HP:0000002 Abnormality of body height Figure Label: HP:0000002 Species: Homo sapiens  Data Points: 558  Description: Abnormality of body height Available to: Everyone (Tier I)
	GS194586: GO:0002376 immune system process Figure Label: GO:0002376 Species: Homo sapiens  Data Points: 1790  Description: "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05] Available to: Everyone (Tier I)
	GS209009: GO:1901576 organic substance biosynthetic process Figure Label: GO:1901576 Species: Homo sapiens  Data Points: 5152  Description: "The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie] Available to: Everyone (Tier I)
	GS190949: GO:0009058 biosynthetic process Figure Label: GO:0009058 Species: Mus musculus  Data Points: 4286  Description: "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." [GOC:curators, ISBN:0198547684] Available to: Everyone (Tier I)
	GS184983: GO:0032550 purine ribonucleoside binding Figure Label: GO:0032550 Species: Mus musculus  Data Points: 1733  Description: "Interacting selectively and non-covalently with a purine ribonucleoside, a compound consisting of a purine base linked to ribose." [GOC:mah] Available to: Everyone (Tier I)
	GS165537: MP:0005376 homeostasis/metabolism phenotype Figure Label: MP:0005376 Species: Mus musculus  Data Points: 4592  Description: homeostasis/metabolism phenotype Available to: Everyone (Tier I)
	GS173694: HP:0001648 Cor pulmonale Figure Label: HP:0001648 Species: Homo sapiens  Data Points: 3  Description: "Right-sided heart failure resulting from chronic hypertension in the pulmonary arteries and right ventricle." [HPO:probinson] Available to: Everyone (Tier I)
	GS135733: dietary obesity 7 (Dob7, Published QTL Chr X) Figure Label: QTL-Dob7-Mouse-Chr X Species: Mus musculus  Data Points: 288  Description: QTL associated with dietary obesity 7. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (132622884) Available to: Everyone (Tier I)
	GS204036: GO:0045321 leukocyte activation Figure Label: GO:0045321 Species: Homo sapiens  Data Points: 550  Description: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor." [GOC:add] Available to: Everyone (Tier I)
	GS174331: HP:0002715 Abnormality of the immune system Figure Label: HP:0002715 Species: Homo sapiens  Data Points: 680  Description: "An abnormality of the `immune system` (FMA:9825)." [HPO:probinson] Available to: Everyone (Tier I)
	GS205480: GO:0002224 toll-like receptor signaling pathway Figure Label: GO:0002224 Species: Homo sapiens  Data Points: 113  Description: "Any series of molecular signals generated as a consequence of binding to a toll-like receptor. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149, PMID:12467241, PMID:12524386, PMID:12855817, PMID:15585605, PMID:15728447] Available to: Everyone (Tier I)
	GS192174: GO:0000166 nucleotide binding Figure Label: GO:0000166 Species: Mus musculus  Data Points: 2263  Description: "Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose." [GOC:mah, ISBN:0198547684] Available to: Everyone (Tier I)
	GS203593: GO:0043227 membrane-bounded organelle Figure Label: GO:0043227 Species: Homo sapiens  Data Points: 9585  Description: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS171346: HP:0002846 Abnormality of B cells Figure Label: HP:0002846 Species: Homo sapiens  Data Points: 89  Description: "An abnormality of `B cells` (CL:0000236)." [HPO:probinson] Available to: Everyone (Tier I)
	GS177308: GO:1901362 organic cyclic compound biosynthetic process Figure Label: GO:1901362 Species: Mus musculus  Data Points: 3005  Description: "The chemical reactions and pathways resulting in the formation of organic cyclic compound." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS127127: Benzo(a)pyrene interacting genes (MeSH:D001564) in CTD Figure Label: D001564 [CTD] Species: Homo sapiens  Data Points: 3171  Description: Genes that interact with the MeSH term 'Benzo(a)pyrene' (D001564). Incorporates data from 239 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene. Available to: Everyone (Tier I)
	GS189231: GO:0002263 cell activation involved in immune response Figure Label: GO:0002263 Species: Mus musculus  Data Points: 140  Description: "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS197623: GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding Figure Label: GO:0005547 Species: Homo sapiens  Data Points: 20  Description: "Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions." [GOC:bf, GOC:jl] Available to: Everyone (Tier I)
	GS168844: MP:0002458 abnormal B cell number Figure Label: MP:0002458 Species: Mus musculus  Data Points: 583  Description: "deviation from the normal count of cells that are formed in the bone marrow, migrate to the peripheral lymphatic system, and mature into plasma cells or memory cells; these cells are involved in humoral immunity" [ISBN:0-8036-0655-99, MGI:smb] Available to: Everyone (Tier I)
	GS184144: GO:0045117 azole transport Figure Label: GO:0045117 Species: Mus musculus  Data Points: 16  Description: "The directed movement of azoles, heterocyclic compounds found in many biologically important substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators, ISBN:3527307206, Wikipedia:Azole] Available to: Everyone (Tier I)
	GS170545: MP:0002022 increased lymphoma incidence Figure Label: MP:0002022 Species: Mus musculus  Data Points: 331  Description: "greater than the expected occurrence of a neoplasm of any lymphoid tissue, occurring in a specific population in a given time period" [ISBN:0-683-40008-8] Available to: Everyone (Tier I)
	GS194605: GO:0001775 cell activation Figure Label: GO:0001775 Species: Homo sapiens  Data Points: 753  Description: "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:mgi_curators] Available to: Everyone (Tier I)
	GS174131: HP:0002011 Abnormality of the central nervous system Figure Label: HP:0002011 Species: Homo sapiens  Data Points: 1495  Description: "An abnormality of the `central nervous system` (FMA:55675)." [HPO:curators] Available to: Everyone (Tier I)
	GS202316: GO:0050789 regulation of biological process Figure Label: GO:0050789 Species: Homo sapiens  Data Points: 8137  Description: "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:ai, GOC:go_curators] Available to: Everyone (Tier I)
	GS194087: GO:0003674 molecular_function Figure Label: GO:0003674 Species: Homo sapiens  Data Points: 15286  Description: "Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions." [GOC:go_curators] Available to: Everyone (Tier I)
	GS206111: GO:0097285 cell-type specific apoptotic process Figure Label: GO:0097285 Species: Homo sapiens  Data Points: 258  Description: "The process of apoptosis in a specific cell type." [GOC:mtg_apoptosis] Available to: Everyone (Tier I)
	GS165937: MP:0008737 abnormal spleen physiology Figure Label: MP:0008737 Species: Mus musculus  Data Points: 87  Description: "any functional anomaly of the organ that filters blood and stores red corpuscles and platelets" [MGI:llw2] Available to: Everyone (Tier I)
	GS191268: GO:0010033 response to organic substance Figure Label: GO:0010033 Species: Mus musculus  Data Points: 1536  Description: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus." [GOC:sm] Available to: Everyone (Tier I)
	GS165242: MP:0008214 increased immature B cell number Figure Label: MP:0008214 Species: Mus musculus  Data Points: 95  Description: "greater number of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity" [ISBN:0-8153-1691-7, MGI:cwg] Available to: Everyone (Tier I)
	GS166560: MP:0008497 decreased IgG2b level Figure Label: MP:0008497 Species: Mus musculus  Data Points: 72  Description: "less than normal immunoglobulin class G2b level" [MGI:tmeehan] Available to: Everyone (Tier I)
	GS167098: MP:0001819 abnormal immune cell physiology Figure Label: MP:0001819 Species: Mus musculus  Data Points: 1576  Description: "any functional anomaly of the cells of the immune system" [MGI:cwg] Available to: Everyone (Tier I)
	GS171898: HP:0011450 CNS infection Figure Label: HP:0011450 Species: Homo sapiens  Data Points: 35  Description: CNS infection Available to: Everyone (Tier I)
	GS177356: GO:0003674 molecular_function Figure Label: GO:0003674 Species: Mus musculus  Data Points: 23365  Description: "Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions." [GOC:go_curators] Available to: Everyone (Tier I)
	GS203590: GO:0043229 intracellular organelle Figure Label: GO:0043229 Species: Homo sapiens  Data Points: 10624  Description: "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS189312: GO:0043299 leukocyte degranulation Figure Label: GO:0043299 Species: Mus musculus  Data Points: 38  Description: "The regulated exocytosis of secretory granules by a leukocyte." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS199032: GO:0036211 protein modification process Figure Label: GO:0036211 Species: Homo sapiens  Data Points: 2464  Description: "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." [GOC:bf, GOC:jl] Available to: Everyone (Tier I)
	GS167321: MP:0003945 abnormal lymphocyte physiology Figure Label: MP:0003945 Species: Mus musculus  Data Points: 1200  Description: "any functional anomaly of any of the white blood cells that includes B cells, T cells, and NK cells" [MGI:monikat] Available to: Everyone (Tier I)
	GS171313: HP:0003139 Panhypogammaglobulinemia Figure Label: HP:0003139 Species: Homo sapiens  Data Points: 10  Description: Panhypogammaglobulinemia Available to: Everyone (Tier I)
	GS175750: HP:0000010 Recurrent urinary tract infections Figure Label: HP:0000010 Species: Homo sapiens  Data Points: 42  Description: "Repeated infections of the urinary tract." [HPO:curators] Available to: Everyone (Tier I)
	GS177309: GO:1901363 heterocyclic compound binding Figure Label: GO:1901363 Species: Mus musculus  Data Points: 4588  Description: "Interacting selectively and non-covalently with heterocyclic compound." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS198285: GO:0004672 protein kinase activity Figure Label: GO:0004672 Species: Homo sapiens  Data Points: 600  Description: "Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP." [MetaCyc:PROTEIN-KINASE-RXN] Available to: Everyone (Tier I)
	GS167708: MP:0002412 increased susceptibility to bacterial infection Figure Label: MP:0002412 Species: Mus musculus  Data Points: 262  Description: "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [MGI:cwg] Available to: Everyone (Tier I)
	GS175119: HP:0001881 Abnormality of leukocytes Figure Label: HP:0001881 Species: Homo sapiens  Data Points: 285  Description: "An abnormality of `leukocytes` (CL:0000738)." [HPO:probinson] Available to: Everyone (Tier I)
	GS164308: MP:0004800 decreased susceptibility to experimental autoimmune encephalomyelitis Figure Label: MP:0004800 Species: Mus musculus  Data Points: 99  Description: "reduced likelihood that an organism will develop disease symptoms similar to human multiple sclerosis upon induction with antigens to Myelin Basic Protein (MBP), Proteolipid Protein (PLP), and/or Myelin Oligodendrocyte glycoprotein (MOG)" [MGI:csmith] Available to: Everyone (Tier I)
	GS168970: MP:0008212 absent mature B cells Figure Label: MP:0008212 Species: Mus musculus  Data Points: 67  Description: "absence of the mature form of a B cell, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex" [CL:0000785, ISBN:0781735149, MGI:csmith] Available to: Everyone (Tier I)
	GS185544: GO:0006979 response to oxidative stress Figure Label: GO:0006979 Species: Mus musculus  Data Points: 203  Description: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:jl, PMID:12115731] Available to: Everyone (Tier I)
	GS206277: GO:0002757 immune response-activating signal transduction Figure Label: GO:0002757 Species: Homo sapiens  Data Points: 235  Description: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an immune response." [GOC:add] Available to: Everyone (Tier I)
	GS188410: GO:0032774 RNA biosynthetic process Figure Label: GO:0032774 Species: Mus musculus  Data Points: 2595  Description: "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers." [GOC:mah] Available to: Everyone (Tier I)
	GS192471: GO:0048869 cellular developmental process Figure Label: GO:0048869 Species: Mus musculus  Data Points: 2710  Description: "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." [GOC:isa_complete] Available to: Everyone (Tier I)
	GS194336: GO:0043412 macromolecule modification Figure Label: GO:0043412 Species: Homo sapiens  Data Points: 2558  Description: "The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties." [GOC:go_curators] Available to: Everyone (Tier I)
	GS167551: MP:0008498 decreased IgG3 level Figure Label: MP:0008498 Species: Mus musculus  Data Points: 101  Description: "less than normal immunoglobulin class G3 level" [MGI:tmeehan] Available to: Everyone (Tier I)
	GS180166: GO:0008152 metabolic process Figure Label: GO:0008152 Species: Mus musculus  Data Points: 9049  Description: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684] Available to: Everyone (Tier I)
	GS171832: HP:0000118 Phenotypic abnormality Figure Label: HP:0000118 Species: Homo sapiens  Data Points: 2339  Description: "A phenotypic abnormality." [HPO:probinson] Available to: Everyone (Tier I)
	GS203886: GO:1901265 nucleoside phosphate binding Figure Label: GO:1901265 Species: Homo sapiens  Data Points: 2433  Description: "Interacting selectively and non-covalently with nucleoside phosphate." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS182740: GO:0018193 peptidyl-amino acid modification Figure Label: GO:0018193 Species: Mus musculus  Data Points: 561  Description: "The alteration of an amino acid residue in a peptide." [GOC:mah] Available to: Everyone (Tier I)
	GS203072: GO:0090304 nucleic acid metabolic process Figure Label: GO:0090304 Species: Homo sapiens  Data Points: 4446  Description: "Any cellular metabolic process involving nucleic acids." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS166059: MP:0009339 decreased splenocyte number Figure Label: MP:0009339 Species: Mus musculus  Data Points: 34  Description: "reduction in the expected number of cells of the spleen" [MGI:csmith] Available to: Everyone (Tier I)
	GS170362: MP:0000717 abnormal lymphocyte cell number Figure Label: MP:0000717 Species: Mus musculus  Data Points: 1205  Description: "deviation from the normal number of the cells involved in adaptive immune reactions of the body in most inflammatory and autoimmune diseases, including B cells, T cells and natural killer cells" [MGI:csmith, MGI:cwg] Available to: Everyone (Tier I)
	GS177382: GO:0097159 organic cyclic compound binding Figure Label: GO:0097159 Species: Mus musculus  Data Points: 4637  Description: "Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure." [CHEBI:33832, GOC:sjw, PMID:7583672] Available to: Everyone (Tier I)
	GS166062: MP:0009333 abnormal splenocyte physiology Figure Label: MP:0009333 Species: Mus musculus  Data Points: 83  Description: "any functional anomaly of a cell of the spleen" [MGI:csmith] Available to: Everyone (Tier I)
	GS193056: GO:0051608 histamine transport Figure Label: GO:0051608 Species: Mus musculus  Data Points: 12  Description: "The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans." [GOC:ai] Available to: Everyone (Tier I)
	GS174337: HP:0002718 Recurrent bacterial infections Figure Label: HP:0002718 Species: Homo sapiens  Data Points: 57  Description: "Increased susceptibility to bacterial infections, as manifested by recurrent episodes of bacterial infection." [HPO:probinson] Available to: Everyone (Tier I)
	GS192509: GO:0006810 transport Figure Label: GO:0006810 Species: Mus musculus  Data Points: 3211  Description: "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore." [GOC:dph, GOC:jl, GOC:mah] Available to: Everyone (Tier I)
	GS166862: MP:0000689 abnormal spleen morphology Figure Label: MP:0000689 Species: Mus musculus  Data Points: 1061  Description: "any structural anomaly of the organ that functions to filter blood and to store red corpuscles and platelets" [ISBN:0-683-40008-8] Available to: Everyone (Tier I)
	GS175524: HP:0000009 Functional abnormality of the bladder Figure Label: HP:0000009 Species: Homo sapiens  Data Points: 136  Description: "`Dysfunction` (PATO:0001641) of the `urinary bladder` (FMA:15900)." [HPO:probinson] Available to: Everyone (Tier I)
	GS202077: GO:0051251 positive regulation of lymphocyte activation Figure Label: GO:0051251 Species: Homo sapiens  Data Points: 214  Description: "Any process that activates or increases the frequency, rate or extent of lymphocyte activation." [GOC:ai] Available to: Everyone (Tier I)
	GS206909: GO:0006952 defense response Figure Label: GO:0006952 Species: Homo sapiens  Data Points: 1100  Description: "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:go_curators] Available to: Everyone (Tier I)
	GS167545: MP:0001793 altered susceptibility to infection Figure Label: MP:0001793 Species: Mus musculus  Data Points: 620  Description: "a change in the likelihood that an organism will develop ill effects from a pathogenic invasion or from components of or toxins produced by pathogens" [ISBN:0-683-40008-8, MGI:cwg] Available to: Everyone (Tier I)
	GS184978: GO:0032555 purine ribonucleotide binding Figure Label: GO:0032555 Species: Mus musculus  Data Points: 1759  Description: "Interacting selectively and non-covalently with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] Available to: Everyone (Tier I)
	GS205604: GO:0002764 immune response-regulating signaling pathway Figure Label: GO:0002764 Species: Homo sapiens  Data Points: 248  Description: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response." [GOC:add, ISBN:0781735149, PMID:15771571] Available to: Everyone (Tier I)
	GS172118: HP:0004332 Abnormality of lymphocytes Figure Label: HP:0004332 Species: Homo sapiens  Data Points: 110  Description: "An abnormality of `lymphocytes` (CL:0000542)." [HPO:probinson] Available to: Everyone (Tier I)
	GS168848: MP:0002452 abnormal antigen presenting cell physiology Figure Label: MP:0002452 Species: Mus musculus  Data Points: 1037  Description: "any functional anomaly of a cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response" [CL:0000145, ISBN:0781735149, MGI:csmith] Available to: Everyone (Tier I)
	GS194872: GO:0004715 non-membrane spanning protein tyrosine kinase activity Figure Label: GO:0004715 Species: Homo sapiens  Data Points: 45  Description: "Catalysis of the reaction: ATP + a non-membrane spanning protein L-tyrosine = ADP + a non-membrane spanning protein L-tyrosine phosphate." [EC:2.7.10.2] Available to: Everyone (Tier I)
	GS170413: MP:0008071 absent B cells Figure Label: MP:0008071 Species: Mus musculus  Data Points: 90  Description: "absence of lymphocytes that expresses membrane-bound antibody, and differentiate into antibody-secreting plasma cells and memory cells upon interaction with antigen; B cells are the primary lymphocyte responsible for humoral immunity, and are most effective against extracellular pathogens" [MGI:csmith] Available to: Everyone (Tier I)
	GS172286: HP:0000824 Growth hormone deficiency Figure Label: HP:0000824 Species: Homo sapiens  Data Points: 20  Description: "Insufficient production of growth hormone, which is produced by the anterior pituitary gland. Growth hormone is a major participant in control of growth and metabolism." [HPO:probinson] Available to: Everyone (Tier I)
	GS175754: HP:0000014 Abnormality of the bladder Figure Label: HP:0000014 Species: Homo sapiens  Data Points: 144  Description: "An abnormality of the `urinary bladder` (FMA:15900)." [HPO:probinson] Available to: Everyone (Tier I)
	GS190714: GO:0016020 membrane Figure Label: GO:0016020 Species: Mus musculus  Data Points: 8145  Description: "Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:mah, ISBN:0815316194] Available to: Everyone (Tier I)
	GS167431: MP:0008523 absent lymph node germinal center Figure Label: MP:0008523 Species: Mus musculus  Data Points: 13  Description: "absence of the area of the lymph node secondary follicle where antigen-activated B-cell blasts are stimulated by antigens and proliferate, with the immunoglobulin genes undergoing somatic hypermutation, before the cells migrate away as plasma cells or memory cells" [PMID:11905817] Available to: Everyone (Tier I)
	GS187751: GO:0019222 regulation of metabolic process Figure Label: GO:0019222 Species: Mus musculus  Data Points: 4518  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] Available to: Everyone (Tier I)
	GS165422: MP:0002494 increased IgM level Figure Label: MP:0002494 Species: Mus musculus  Data Points: 160  Description: "greater than normal immunoglobulin class M level" [MGI:cwg] Available to: Everyone (Tier I)
	GS209480: GO:0006955 immune response Figure Label: GO:0006955 Species: Homo sapiens  Data Points: 1055  Description: "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05] Available to: Everyone (Tier I)
	GS188322: GO:0005524 ATP binding Figure Label: GO:0005524 Species: Mus musculus  Data Points: 1418  Description: "Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS195214: GO:0009987 cellular process Figure Label: GO:0009987 Species: Homo sapiens  Data Points: 12850  Description: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete] Available to: Everyone (Tier I)
	GS207177: GO:0050864 regulation of B cell activation Figure Label: GO:0050864 Species: Homo sapiens  Data Points: 82  Description: "Any process that modulates the frequency, rate or extent of B cell activation." [GOC:ai] Available to: Everyone (Tier I)
	GS163934: MP:0001764 abnormal homeostasis Figure Label: MP:0001764 Species: Mus musculus  Data Points: 3924  Description: "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions and chemical or protein composition of the fluids and tissues" [ISBN:0-683-40008-8] Available to: Everyone (Tier I)
	GS204204: GO:0006351 transcription, DNA-dependent Figure Label: GO:0006351 Species: Homo sapiens  Data Points: 3201  Description: "The cellular synthesis of RNA on a template of DNA." [GOC:jl, GOC:txnOH] Available to: Everyone (Tier I)
	GS180034: GO:0032502 developmental process Figure Label: GO:0032502 Species: Mus musculus  Data Points: 4073  Description: "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." [GOC:isa_complete] Available to: Everyone (Tier I)
	GS201729: GO:0002253 activation of immune response Figure Label: GO:0002253 Species: Homo sapiens  Data Points: 305  Description: "Any process that initiates an immune response." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS175128: HP:0011123 Inflammatory abnormality of the skin Figure Label: HP:0011123 Species: Homo sapiens  Data Points: 144  Description: "The presence of `inflammation` (MPATH:212) of the `skin` (FMA:7163). That is, an abnormality of the skin resulting from the local accumulation of fluid, plasma proteins, and leukocytes." [HPO:probinson] Available to: Everyone (Tier I)
	GS199124: GO:0051716 cellular response to stimulus Figure Label: GO:0051716 Species: Homo sapiens  Data Points: 4983  Description: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." [GOC:bf, GOC:jl] Available to: Everyone (Tier I)
	GS200648: GO:0044260 cellular macromolecule metabolic process Figure Label: GO:0044260 Species: Homo sapiens  Data Points: 6651  Description: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS167440: MP:0000334 decreased granulocyte number Figure Label: MP:0000334 Species: Mus musculus  Data Points: 162  Description: "fewer than expected number of leukocytes that have abundant granules in the cytoplasm, including basophils, neutrophils, and eosinophils" [MGI:cwg] Available to: Everyone (Tier I)
	GS165525: MP:0010768 mortality/aging Figure Label: MP:0010768 Species: Mus musculus  Data Points: 5057  Description: "characteristics involving the ability of an organism to live and age normally throughout development and life span" [MGI:csmith] Available to: Everyone (Tier I)
	GS193639: GO:0051641 cellular localization Figure Label: GO:0051641 Species: Mus musculus  Data Points: 1608  Description: "A localization process that takes place at the cellular level; as a result of a cellular localization process, a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell." [GOC:ai, GOC:mah] Available to: Everyone (Tier I)
	GS201794: GO:0032555 purine ribonucleotide binding Figure Label: GO:0032555 Species: Homo sapiens  Data Points: 1862  Description: "Interacting selectively and non-covalently with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] Available to: Everyone (Tier I)
	GS169025: MP:0001657 abnormal induced morbidity/mortality Figure Label: MP:0001657 Species: Mus musculus  Data Points: 563  Description: "differences from the expected diseased state or death caused by an external intervention" [MGI:cwg] Available to: Everyone (Tier I)
	GS203392: GO:0035091 phosphatidylinositol binding Figure Label: GO:0035091 Species: Homo sapiens  Data Points: 153  Description: "Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives." [GOC:bf, ISBN:0198506732, PMID:11395417] Available to: Everyone (Tier I)
	GS184684: GO:0021700 developmental maturation Figure Label: GO:0021700 Species: Mus musculus  Data Points: 213  Description: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:mtg_15jun06] Available to: Everyone (Tier I)
	GS185259: GO:0051252 regulation of RNA metabolic process Figure Label: GO:0051252 Species: Mus musculus  Data Points: 2598  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] Available to: Everyone (Tier I)
	GS203642: GO:0006725 cellular aromatic compound metabolic process Figure Label: GO:0006725 Species: Homo sapiens  Data Points: 5379  Description: "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells." [GOC:ai, ISBN:0198506732] Available to: Everyone (Tier I)
	GS194683: GO:0050851 antigen receptor-mediated signaling pathway Figure Label: GO:0050851 Species: Homo sapiens  Data Points: 122  Description: "A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell." [GOC:add] Available to: Everyone (Tier I)
	GS174335: HP:0001871 Abnormality of blood and blood-forming tissues Figure Label: HP:0001871 Species: Homo sapiens  Data Points: 626  Description: "An abnormality of the `hematopoietic system` (FMA:9667)." [HPO:probinson] Available to: Everyone (Tier I)
	GS175714: HP:0011389 Functional abnormality of the inner ear Figure Label: HP:0011389 Species: Homo sapiens  Data Points: 381  Description: "An abnormality of the function of the inner ear." [DDD:dfitzpatrick] Available to: Everyone (Tier I)
	GS207923: GO:0034641 cellular nitrogen compound metabolic process Figure Label: GO:0034641 Species: Homo sapiens  Data Points: 5601  Description: "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." [GOC:mah] Available to: Everyone (Tier I)
	GS187023: GO:1901265 nucleoside phosphate binding Figure Label: GO:1901265 Species: Mus musculus  Data Points: 2263  Description: "Interacting selectively and non-covalently with nucleoside phosphate." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS198483: GO:0034142 toll-like receptor 4 signaling pathway Figure Label: GO:0034142 Species: Homo sapiens  Data Points: 89  Description: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 4." [GOC:add, PMID:16551253, PMID:17328678] Available to: Everyone (Tier I)
	GS165265: MP:0005014 increased B cell number Figure Label: MP:0005014 Species: Mus musculus  Data Points: 301  Description: "greater than normal number of cells that are formed in the bone marrow, migrate to the peripheral lymphatic system, and mature into plasma cells or memory cells; these cells are involved in humoral immunity" [ISBN:0-8036-0655-99, MGI:smb] Available to: Everyone (Tier I)
	GS192296: GO:0006796 phosphate-containing compound metabolic process Figure Label: GO:0006796 Species: Mus musculus  Data Points: 2507  Description: "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." [GOC:ai] Available to: Everyone (Tier I)
	GS198263: GO:0005488 binding Figure Label: GO:0005488 Species: Homo sapiens  Data Points: 11955  Description: "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." [GOC:ceb, GOC:mah, ISBN:0198506732] Available to: Everyone (Tier I)
	GS205145: GO:0048469 cell maturation Figure Label: GO:0048469 Species: Homo sapiens  Data Points: 117  Description: "A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state." [GOC:go_curators] Available to: Everyone (Tier I)
	GS194040: GO:1901360 organic cyclic compound metabolic process Figure Label: GO:1901360 Species: Homo sapiens  Data Points: 5558  Description: "The chemical reactions and pathways involving organic cyclic compound." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS171527: HP:0001707 Abnormality of the right ventricle Figure Label: HP:0001707 Species: Homo sapiens  Data Points: 9  Description: "An abnormality of the `right ventricle` (FMA:7098) of the heart." [HPO:probinson] Available to: Everyone (Tier I)
	GS206355: GO:0023052 signaling Figure Label: GO:0023052 Species: Homo sapiens  Data Points: 4593  Description: "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." [GOC:mtg_signal, GOC:mtg_signaling_feb11, GOC:signaling] Available to: Everyone (Tier I)
	GS170544: MP:0002023 B cell derived lymphoma Figure Label: MP:0002023 Species: Mus musculus  Data Points: 110  Description: "heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes" [MESH:C04.557.386.480.150] Available to: Everyone (Tier I)
	GS192918: GO:0050896 response to stimulus Figure Label: GO:0050896 Species: Mus musculus  Data Points: 6947  Description: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." [GOC:ai, GOC:bf] Available to: Everyone (Tier I)
	GS175431: HP:0011122 Abnormality of skin physiology Figure Label: HP:0011122 Species: Homo sapiens  Data Points: 177  Description: "Any abnormality of the physiological function of the `skin` (FMA:7163)." [HPO:probinson] Available to: Everyone (Tier I)
	GS210424: GO:0045619 regulation of lymphocyte differentiation Figure Label: GO:0045619 Species: Homo sapiens  Data Points: 103  Description: "Any process that modulates the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] Available to: Everyone (Tier I)
	GS186798: GO:0030554 adenyl nucleotide binding Figure Label: GO:0030554 Species: Mus musculus  Data Points: 1449  Description: "Interacting selectively and non-covalently with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS190067: GO:0018130 heterocycle biosynthetic process Figure Label: GO:0018130 Species: Mus musculus  Data Points: 2917  Description: "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198547684] Available to: Everyone (Tier I)
	GS165524: MP:0010769 abnormal survival Figure Label: MP:0010769 Species: Mus musculus  Data Points: 4772  Description: "deviation from the expected viability or life span of an organism" [MGI:csmith] Available to: Everyone (Tier I)
	GS170971: HP:0000407 Sensorineural hearing impairment Figure Label: HP:0000407 Species: Homo sapiens  Data Points: 368  Description: "A type of `hearing impairment` (HP:0000365) in one or both ears related to an `abnormal` (PATO:0000460) `functionality` (PATO:0001509) of the `cochlear nerve` (FMA:53431)." [HPO:probinson] Available to: Everyone (Tier I)
	GS175423: HP:0010461 Abnormality of the male genitalia Figure Label: HP:0010461 Species: Homo sapiens  Data Points: 445  Description: "Abnormality of the `male genital system` (FMA:45664)." [HPO:probinson] Available to: Everyone (Tier I)
	GS163609: MP:0008781 abnormal B cell apoptosis Figure Label: MP:0008781 Species: Mus musculus  Data Points: 74  Description: "change in the timing or the number of B cells undergoing programmed cell death" [MGI:csmith] Available to: Everyone (Tier I)
	GS171559: HP:0000388 Otitis media Figure Label: HP:0000388 Species: Homo sapiens  Data Points: 65  Description: "Inflammation or infection of the middle ear." [HPO:probinson] Available to: Everyone (Tier I)
	GS162989: MP:0001806 decreased IgM level Figure Label: MP:0001806 Species: Mus musculus  Data Points: 133  Description: "less than normal immunoglobulin class M level" [MGI:cwg] Available to: Everyone (Tier I)
	GS209235: GO:0006793 phosphorus metabolic process Figure Label: GO:0006793 Species: Homo sapiens  Data Points: 2494  Description: "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." [GOC:ai] Available to: Everyone (Tier I)
	GS203306: GO:0045577 regulation of B cell differentiation Figure Label: GO:0045577 Species: Homo sapiens  Data Points: 19  Description: "Any process that modulates the frequency, rate or extent of B cell differentiation." [GOC:go_curators] Available to: Everyone (Tier I)
	GS205266: GO:0032774 RNA biosynthetic process Figure Label: GO:0032774 Species: Homo sapiens  Data Points: 3287  Description: "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers." [GOC:mah] Available to: Everyone (Tier I)
	GS195977: GO:0007154 cell communication Figure Label: GO:0007154 Species: Homo sapiens  Data Points: 4719  Description: "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:mah] Available to: Everyone (Tier I)
	GS206418: GO:0002443 leukocyte mediated immunity Figure Label: GO:0002443 Species: Homo sapiens  Data Points: 220  Description: "Any process involved in the carrying out of an immune response by a leukocyte." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS170617: MP:0005022 abnormal immature B cell morphology Figure Label: MP:0005022 Species: Mus musculus  Data Points: 240  Description: "any structural anomaly of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity" [ISBN:0-8153-1691-7, MGI:cwg] Available to: Everyone (Tier I)
	GS186982: GO:0018212 peptidyl-tyrosine modification Figure Label: GO:0018212 Species: Mus musculus  Data Points: 208  Description: "The modification of peptidyl-tyrosine." [GOC:go_curators] Available to: Everyone (Tier I)
	GS165742: MP:0008472 abnormal spleen secondary B follicle morphology Figure Label: MP:0008472 Species: Mus musculus  Data Points: 127  Description: "any structural anomaly of the nodules of antigen-activated, differentiating B cells, follicular dendritic cells, antigen-presenting T cells and macrophages in the spleen white pulp" [PMID:17495967] Available to: Everyone (Tier I)
	GS194023: GO:2000106 regulation of leukocyte apoptotic process Figure Label: GO:2000106 Species: Homo sapiens  Data Points: 43  Description: "Any process that modulates the frequency, rate or extent of leukocyte apoptosis." [GOC:BHF] Available to: Everyone (Tier I)
	GS194905: GO:0008219 cell death Figure Label: GO:0008219 Species: Homo sapiens  Data Points: 1697  Description: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as "apoptotic bodies"); and/or (3) its corpse (or its fragments) have been engulfed by an adjacent cell in vivo." [GOC:mah, GOC:mtg_apoptosis] Available to: Everyone (Tier I)
	GS194267: GO:0043170 macromolecule metabolic process Figure Label: GO:0043170 Species: Homo sapiens  Data Points: 7311  Description: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS198274: GO:0035556 intracellular signal transduction Figure Label: GO:0035556 Species: Homo sapiens  Data Points: 1817  Description: "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:signaling, ISBN:3527303782] Available to: Everyone (Tier I)
	GS210357: GO:0044249 cellular biosynthetic process Figure Label: GO:0044249 Species: Homo sapiens  Data Points: 5047  Description: "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:jl] Available to: Everyone (Tier I)
	GS180452: GO:0044237 cellular metabolic process Figure Label: GO:0044237 Species: Mus musculus  Data Points: 7552  Description: "The chemical reactions and pathways by which individual cells transform chemical substances." [GOC:go_curators] Available to: Everyone (Tier I)
	GS174136: HP:0002014 Diarrhea Figure Label: HP:0002014 Species: Homo sapiens  Data Points: 109  Description: "Abnormally increased frequency of loose or watery bowel movements." [HPO:probinson] Available to: Everyone (Tier I)
	GS201106: GO:0002218 activation of innate immune response Figure Label: GO:0002218 Species: Homo sapiens  Data Points: 137  Description: "Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, GOC:mtg_sensu, ISBN:0781735149, PMID:15199967, PMID:16177805] Available to: Everyone (Tier I)
	GS204735: GO:0045121 membrane raft Figure Label: GO:0045121 Species: Homo sapiens  Data Points: 197  Description: "Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions." [PMID:16645198] Available to: Everyone (Tier I)
	GS173538: HP:0001873 Thrombocytopenia Figure Label: HP:0001873 Species: Homo sapiens  Data Points: 121  Description: "A reduction in the number of circulating `thrombocytes` (CL:0000762)." [HPO:probinson] Available to: Everyone (Tier I)
	GS167717: MP:0002419 abnormal innate immunity Figure Label: MP:0002419 Species: Mus musculus  Data Points: 604  Description: "anomaly in the function of the early phase of the response to infection; normally, it is present at all times, does not increase with exposure to specific pathogens, and does not discriminate between pathogens" [ISBN:0-8153-1691-7] Available to: Everyone (Tier I)
	GS206953: GO:0018130 heterocycle biosynthetic process Figure Label: GO:0018130 Species: Homo sapiens  Data Points: 3640  Description: "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198547684] Available to: Everyone (Tier I)
	GS203057: GO:0048518 positive regulation of biological process Figure Label: GO:0048518 Species: Homo sapiens  Data Points: 3446  Description: "Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid] Available to: Everyone (Tier I)
	GS167589: MP:0005016 decreased lymphocyte cell number Figure Label: MP:0005016 Species: Mus musculus  Data Points: 934  Description: "fewer than normal number of the cells involved in adaptive immune reactions of the body in most inflammatory and autoimmune diseases, including B cells, T cells and natural killer cells" [MGI:csmith, MGI:cwg] Available to: Everyone (Tier I)
	GS188288: GO:0048469 cell maturation Figure Label: GO:0048469 Species: Mus musculus  Data Points: 122  Description: "A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state." [GOC:go_curators] Available to: Everyone (Tier I)
	GS170858: HP:0002901 Hypocalcemia Figure Label: HP:0002901 Species: Homo sapiens  Data Points: 30  Description: "An abnormally decreased `calcium` (CHEBI:29108) concentration in the blood." [HPO:curators] Available to: Everyone (Tier I)
	GS174453: HP:0001438 Abnormality of the abdomen Figure Label: HP:0001438 Species: Homo sapiens  Data Points: 1051  Description: "Abnormality of the `abdomen` (FMA:9577) ('belly'), that is, the part of the body between the pelvis and the thorax." [HPO:probinson] Available to: Everyone (Tier I)
	GS194499: GO:0044271 cellular nitrogen compound biosynthetic process Figure Label: GO:0044271 Species: Homo sapiens  Data Points: 3721  Description: "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732] Available to: Everyone (Tier I)
	GS180164: GO:0008150 biological_process Figure Label: GO:0008150 Species: Mus musculus  Data Points: 23855  Description: "Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end." [GOC:go_curators, GOC:isa_complete] Available to: Everyone (Tier I)
	GS168995: MP:0009642 abnormal blood homeostasis Figure Label: MP:0009642 Species: Mus musculus  Data Points: 2663  Description: "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8, MGI:csmith] Available to: Everyone (Tier I)
	GS177531: GO:0043170 macromolecule metabolic process Figure Label: GO:0043170 Species: Mus musculus  Data Points: 6435  Description: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS188287: GO:0048468 cell development Figure Label: GO:0048468 Species: Mus musculus  Data Points: 1378  Description: "The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:go_curators] Available to: Everyone (Tier I)
	GS173962: HP:0001581 Recurrent skin infections Figure Label: HP:0001581 Species: Homo sapiens  Data Points: 34  Description: "Infections of the skin that happen multiple times." [HPO:curators] Available to: Everyone (Tier I)
	GS175765: HP:0001419 X-linked recessive inheritance Figure Label: HP:0001419 Species: Homo sapiens  Data Points: 82  Description: "A mode of inheritance that is observed for recessive traits related to a gene encoded on the X chromosome. In the context of medical genetics, X-linked recessive disorders manifest in males (who have one copy of the X chromosome and are thus hemizygotes), but generally not in female heterozygotes who have one mutant and one normal allele." [HPO:curators] Available to: Everyone (Tier I)
	GS196986: GO:0045597 positive regulation of cell differentiation Figure Label: GO:0045597 Species: Homo sapiens  Data Points: 498  Description: "Any process that activates or increases the frequency, rate or extent of cell differentiation." [GOC:go_curators] Available to: Everyone (Tier I)
	GS206415: GO:0002440 production of molecular mediator of immune response Figure Label: GO:0002440 Species: Homo sapiens  Data Points: 109  Description: "The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS205179: GO:0005524 ATP binding Figure Label: GO:0005524 Species: Homo sapiens  Data Points: 1480  Description: "Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS205255: GO:0044238 primary metabolic process Figure Label: GO:0044238 Species: Homo sapiens  Data Points: 8702  Description: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] Available to: Everyone (Tier I)
	GS170479: MP:0008522 abnormal lymph node germinal center morphology Figure Label: MP:0008522 Species: Mus musculus  Data Points: 30  Description: "any structural anomaly of the area of the lymph node secondary follicle where antigen-activated B-cell blasts are stimulated by antigens and proliferate, with the immunoglobulin genes undergoing somatic hypermutation, before the cells migrate away as plasma cells or memory cells" [PMID:11905817] Available to: Everyone (Tier I)
	GS171833: HP:0000119 Abnormality of the genitourinary system Figure Label: HP:0000119 Species: Homo sapiens  Data Points: 990  Description: "The presence of any abnormality of the `genitourinary system` (FMA:280610)." [HPO:curators] Available to: Everyone (Tier I)
	GS167575: MP:0005013 increased lymphocyte cell number Figure Label: MP:0005013 Species: Mus musculus  Data Points: 704  Description: "greater than normal number of the cells involved in adaptive immune reactions of the body in most inflammatory and autoimmune diseases, including B cells, T cells and natural killer cells" [MGI:csmith, MGI:cwg] Available to: Everyone (Tier I)
	GS169917: MP:0010155 abnormal intestine physiology Figure Label: MP:0010155 Species: Mus musculus  Data Points: 303  Description: "any functional anomaly of the digestive tube passing from the stomach to the anus" [MGI:csmith] Available to: Everyone (Tier I)
	GS191090: GO:0004713 protein tyrosine kinase activity Figure Label: GO:0004713 Species: Mus musculus  Data Points: 136  Description: "Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate." [EC:2.7.10] Available to: Everyone (Tier I)
	GS167987: MP:0003132 increased pre-B cell number Figure Label: MP:0003132 Species: Mus musculus  Data Points: 46  Description: "greater number of progenitor cells that form the B cell component of the immune system" [ISBN:0-8153-1691-7, MGI:smb] Available to: Everyone (Tier I)
	GS181483: GO:0035556 intracellular signal transduction Figure Label: GO:0035556 Species: Mus musculus  Data Points: 1548  Description: "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:signaling, ISBN:3527303782] Available to: Everyone (Tier I)
	GS197588: GO:0070228 regulation of lymphocyte apoptotic process Figure Label: GO:0070228 Species: Homo sapiens  Data Points: 30  Description: "Any process that modulates the occurrence or rate of lymphocyte death by apoptosis." [GOC:add, ISBN:0781765196] Available to: Everyone (Tier I)
	GS170081: MP:0001858 intestinal inflammation Figure Label: MP:0001858 Species: Mus musculus  Data Points: 225  Description: "local accumulation of fluid, plasma proteins, and leukocytes in the intestine" [ISBN:0-8153-1691-7, MGI:cwg] Available to: Everyone (Tier I)
	GS175136: HP:0000024 Prostatitis Figure Label: HP:0000024 Species: Homo sapiens  Data Points: 2  Description: "The presence of `inflammation` (MPATH:212) of the `prostate` (FMA:9600)." [HPO:probinson] Available to: Everyone (Tier I)
	GS207858: GO:0009059 macromolecule biosynthetic process Figure Label: GO:0009059 Species: Homo sapiens  Data Points: 4276  Description: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS209232: GO:0006796 phosphate-containing compound metabolic process Figure Label: GO:0006796 Species: Homo sapiens  Data Points: 2431  Description: "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." [GOC:ai] Available to: Everyone (Tier I)
	GS177721: GO:0051234 establishment of localization Figure Label: GO:0051234 Species: Mus musculus  Data Points: 3268  Description: "The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location." [GOC:ai] Available to: Everyone (Tier I)
	GS186460: GO:0045576 mast cell activation Figure Label: GO:0045576 Species: Mus musculus  Data Points: 41  Description: "The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors." [GOC:mgi_curators, ISBN:0781735149] Available to: Everyone (Tier I)
	GS165417: MP:0002493 increased IgG level Figure Label: MP:0002493 Species: Mus musculus  Data Points: 253  Description: "greater than normal immunoglobulin class G level" [MGI:cwg] Available to: Everyone (Tier I)
	GS209455: GO:0003824 catalytic activity Figure Label: GO:0003824 Species: Homo sapiens  Data Points: 5321  Description: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS184218: GO:0071704 organic substance metabolic process Figure Label: GO:0071704 Species: Mus musculus  Data Points: 8072  Description: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [CHEBI:50860, GOC:mah] Available to: Everyone (Tier I)
	GS164605: MP:0002339 abnormal lymph node morphology Figure Label: MP:0002339 Species: Mus musculus  Data Points: 426  Description: "any structural anomaly of the oval or bean shaped bodies located along the lymphatic system that consist of densely packed lymphocytes, lymph fluid and connective tissue, and is the site where acquired immune responses are launched" [MESH:A10.549.400, MGI:csmith] Available to: Everyone (Tier I)
	GS200602: GO:0044267 cellular protein metabolic process Figure Label: GO:0044267 Species: Homo sapiens  Data Points: 3254  Description: "The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification." [GOC:jl] Available to: Everyone (Tier I)
	GS163568: MP:0002551 abnormal blood coagulation Figure Label: MP:0002551 Species: Mus musculus  Data Points: 280  Description: "altered ability or inability of the blood to clot" [MGI:csmith] Available to: Everyone (Tier I)
	GS169700: MP:0004940 abnormal B-1 B cell morphology Figure Label: MP:0004940 Species: Mus musculus  Data Points: 126  Description: "any structural anomaly of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and are enriched for self-reactivity; B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas" [CL:0000819, MGI:csmith, PMID:11861604] Available to: Everyone (Tier I)
	GS193563: GO:0006950 response to stress Figure Label: GO:0006950 Species: Mus musculus  Data Points: 2101  Description: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah] Available to: Everyone (Tier I)
	GS126769: Calcium interacting genes (MeSH:D002118) in CTD Figure Label: D002118 [CTD] Species: Homo sapiens  Data Points: 306  Description: Genes that interact with the MeSH term 'Calcium' (D002118). Incorporates data from 283 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene. Available to: Everyone (Tier I)
	GS183514: GO:0019219 regulation of nucleobase-containing compound metabolic process Figure Label: GO:0019219 Species: Mus musculus  Data Points: 2982  Description: "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] Available to: Everyone (Tier I)
	GS866: Linear decrease in expression in both Pax6 (Sey) mutants and controls. Figure Label: Sey_Pax6_Age_Reduced_Lin Species: Mus musculus  Data Points: 2551  Description: Linear decrease in cerebellar gene expression across three developmental time points in both Pax6 Sey (Small-eyes) mutants and controls. Available to: Everyone (Tier III)
	GS183848: GO:0044260 cellular macromolecule metabolic process Figure Label: GO:0044260 Species: Mus musculus  Data Points: 5650  Description: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS186757: GO:0034654 nucleobase-containing compound biosynthetic process Figure Label: GO:0034654 Species: Mus musculus  Data Points: 2855  Description: "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah] Available to: Everyone (Tier I)
	GS169304: MP:0008251 abnormal phagocyte morphology Figure Label: MP:0008251 Species: Mus musculus  Data Points: 670  Description: "any structural anomaly of cells capable of ingesting particulate matter via phagocytosis" [CL:0000234, ISBN:0721601464] Available to: Everyone (Tier I)
	GS174646: HP:0000951 Abnormality of the skin Figure Label: HP:0000951 Species: Homo sapiens  Data Points: 882  Description: "An abnormality of the `skin` (FMA:7163)." [HPO:probinson] Available to: Everyone (Tier I)
	GS170573: MP:0004976 abnormal B-1 B cell number Figure Label: MP:0004976 Species: Mus musculus  Data Points: 123  Description: "deviation from the normal count of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity" [MGI:csmith] Available to: Everyone (Tier I)
	GS193549: GO:0002275 myeloid cell activation involved in immune response Figure Label: GO:0002275 Species: Mus musculus  Data Points: 51  Description: "A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] Available to: Everyone (Tier I)
	GS181493: GO:0004672 protein kinase activity Figure Label: GO:0004672 Species: Mus musculus  Data Points: 564  Description: "Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP." [MetaCyc:PROTEIN-KINASE-RXN] Available to: Everyone (Tier I)
	GS170651: MP:0002344 abnormal lymph node B cell domain morphology Figure Label: MP:0002344 Species: Mus musculus  Data Points: 56  Description: "any structural anomaly of the part of the lymph node cortex in which B lymphocytes home to primary follicles to survey follicular dendritic cells (FDCs); antigen stimulated B cells proliferate and differentiate within the follicles forming distinctive germinal centers" [PMID:17067937] Available to: Everyone (Tier I)
	GS198685: GO:0048522 positive regulation of cellular process Figure Label: GO:0048522 Species: Homo sapiens  Data Points: 3121  Description: "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid] Available to: Everyone (Tier I)
	GS191266: GO:0010035 response to inorganic substance Figure Label: GO:0010035 Species: Mus musculus  Data Points: 326  Description: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus." [GOC:sm] Available to: Everyone (Tier I)
	GS201949: GO:0044699 single-organism process Figure Label: GO:0044699 Species: Homo sapiens  Data Points: 7638  Description: "A biological process that involves only one organism." [GOC:jl] Available to: Everyone (Tier I)
	GS208954: GO:0006139 nucleobase-containing compound metabolic process Figure Label: GO:0006139 Species: Homo sapiens  Data Points: 5216  Description: "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:ai] Available to: Everyone (Tier I)
	GS200015: GO:0001816 cytokine production Figure Label: GO:0001816 Species: Homo sapiens  Data Points: 421  Description: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] Available to: Everyone (Tier I)
	GS202902: GO:0050871 positive regulation of B cell activation Figure Label: GO:0050871 Species: Homo sapiens  Data Points: 55  Description: "Any process that activates or increases the frequency, rate or extent of B cell activation." [GOC:ai] Available to: Everyone (Tier I)
	GS184583: GO:0043303 mast cell degranulation Figure Label: GO:0043303 Species: Mus musculus  Data Points: 27  Description: "The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell." [ISBN:0781735149] Available to: Everyone (Tier I)
	GS188641: GO:0071944 cell periphery Figure Label: GO:0071944 Species: Mus musculus  Data Points: 3706  Description: "The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures." [GOC:mah] Available to: Everyone (Tier I)
	GS168086: MP:0000172 abnormal bone marrow cell number Figure Label: MP:0000172 Species: Mus musculus  Data Points: 209  Description: "increased or decreased number of cells that make up the core cavities of bones when compared to controls" [MGI:tc] Available to: Everyone (Tier I)
	GS193874: GO:0018108 peptidyl-tyrosine phosphorylation Figure Label: GO:0018108 Species: Homo sapiens  Data Points: 200  Description: "The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine." [RESID:AA0039] Available to: Everyone (Tier I)
	GS190950: GO:0009059 macromolecule biosynthetic process Figure Label: GO:0009059 Species: Mus musculus  Data Points: 3473  Description: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [CHEBI:33694, GOC:mah] Available to: Everyone (Tier I)
	GS178461: GO:0009987 cellular process Figure Label: GO:0009987 Species: Mus musculus  Data Points: 13263  Description: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete] Available to: Everyone (Tier I)
	GS189550: GO:0002444 myeloid leukocyte mediated immunity Figure Label: GO:0002444 Species: Mus musculus  Data Points: 51  Description: "Any process involved in the carrying out of an immune response by a myeloid leukocyte." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS193061: GO:0044444 cytoplasmic part Figure Label: GO:0044444 Species: Mus musculus  Data Points: 5588  Description: "Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GOC:jl] Available to: Everyone (Tier I)
	GS192624: GO:0043231 intracellular membrane-bounded organelle Figure Label: GO:0043231 Species: Mus musculus  Data Points: 8630  Description: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS186743: GO:0043227 membrane-bounded organelle Figure Label: GO:0043227 Species: Mus musculus  Data Points: 8650  Description: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] Available to: Everyone (Tier I)
	GS192041: GO:0043169 cation binding Figure Label: GO:0043169 Species: Mus musculus  Data Points: 3537  Description: "Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge." [GOC:jl] Available to: Everyone (Tier I)
	GS171901: HP:0010985 Gonosomal inheritance Figure Label: HP:0010985 Species: Homo sapiens  Data Points: 166  Description: "A mode of inheritance that is observed for traits related to a gene encoded on the sex chromosomes." [HPO:probinson] Available to: Everyone (Tier I)
	GS210507: GO:0006950 response to stress Figure Label: GO:0006950 Species: Homo sapiens  Data Points: 2940  Description: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah] Available to: Everyone (Tier I)
	GS173384: HP:0002750 Delayed skeletal maturation Figure Label: HP:0002750 Species: Homo sapiens  Data Points: 125  Description: "A decreased rate of skeletal maturation. Delayed skeletal maturation can be diagnosed on the basis of an estimation of the bone age from radiographs of specific bones in the human body." [HPO:curators] Available to: Everyone (Tier I)
	GS174372: HP:0002024 Malabsorption Figure Label: HP:0002024 Species: Homo sapiens  Data Points: 103  Description: "Impaired ability to absorb one or more nutrients from the intestine." [HPO:probinson] Available to: Everyone (Tier I)
	GS162984: MP:0001800 abnormal humoral immune response Figure Label: MP:0001800 Species: Mus musculus  Data Points: 646  Description: "any functional anomaly of the aspect of immunity that is mediated by secreted antibodies produced in the cells of the B lymphocyte lineage (B cell) and the accessory processes that accompany it, including Th2 activation and cytokine production, germinal center formation and isotype switching, affinity maturation and memory cell generation; it also refers to the effector functions of antibody, which include pathogen and toxin neutralization, classical complement activation, and opsonin promotion of phagocytosis and pathogen elimination" [ISBN:081533642X, MGI:csmith] Available to: Everyone (Tier I)
	GS169973: MP:0002006 tumorigenesis Figure Label: MP:0002006 Species: Mus musculus  Data Points: 1386  Description: tumorigenesis Available to: Everyone (Tier I)
	GS187033: GO:0006887 exocytosis Figure Label: GO:0006887 Species: Mus musculus  Data Points: 188  Description: "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process in which most molecules are secreted from eukaryotic cells." [GOC:mah, ISBN:0716731363] Available to: Everyone (Tier I)
	GS203276: GO:0007243 intracellular protein kinase cascade Figure Label: GO:0007243 Species: Homo sapiens  Data Points: 849  Description: "A series of reactions in which a signal is passed on to downstream proteins within the cell by sequential protein phosphorylation and activation of the cascade components." [GOC:bf, GOC:jl, GOC:signaling] Available to: Everyone (Tier I)
	GS179830: GO:0006464 cellular protein modification process Figure Label: GO:0006464 Species: Mus musculus  Data Points: 2223  Description: "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." [GOC:go_curators] Available to: Everyone (Tier I)
	GS201728: GO:0002250 adaptive immune response Figure Label: GO:0002250 Species: Homo sapiens  Data Points: 207  Description: "An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory)." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS193268: GO:0005575 cellular_component Figure Label: GO:0005575 Species: Mus musculus  Data Points: 23784  Description: "The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together." [GOC:go_curators] Available to: Everyone (Tier I)
	GS194039: GO:1901363 heterocyclic compound binding Figure Label: GO:1901363 Species: Homo sapiens  Data Points: 5400  Description: "Interacting selectively and non-covalently with heterocyclic compound." [GOC:TermGenie] Available to: Everyone (Tier I)
	GS188190: GO:0006807 nitrogen compound metabolic process Figure Label: GO:0006807 Species: Mus musculus  Data Points: 4887  Description: "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium." [CHEBI:51143, GOC:go_curators, GOC:jl, ISBN:0198506732] Available to: Everyone (Tier I)
	GS184217: GO:0071705 nitrogen compound transport Figure Label: GO:0071705 Species: Mus musculus  Data Points: 494  Description: "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [CHEBI:51143, GOC:mah] Available to: Everyone (Tier I)
	GS193151: GO:0032940 secretion by cell Figure Label: GO:0032940 Species: Mus musculus  Data Points: 582  Description: "The controlled release of a substance by a cell." [GOC:mah] Available to: Everyone (Tier I)
	GS199019: GO:0002367 cytokine production involved in immune response Figure Label: GO:0002367 Species: Homo sapiens  Data Points: 46  Description: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS209215: GO:0007166 cell surface receptor signaling pathway Figure Label: GO:0007166 Species: Homo sapiens  Data Points: 2317  Description: "A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:mah, GOC:pr, GOC:signaling] Available to: Everyone (Tier I)
	GS207797: GO:0030154 cell differentiation Figure Label: GO:0030154 Species: Homo sapiens  Data Points: 2661  Description: "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS207581: GO:0007275 multicellular organismal development Figure Label: GO:0007275 Species: Homo sapiens  Data Points: 4070  Description: "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:dph, GOC:ems, GOC:isa_complete, GOC:tb] Available to: Everyone (Tier I)
	GS172358: HP:0003117 Abnormality of circulating hormone level Figure Label: HP:0003117 Species: Homo sapiens  Data Points: 120  Description: "An `abnormal` (PATO:0000460) `concentration` (PATO:0000033) of a `hormone` (CHEBI:24621) in the `blood` (FMA:9670)." [HPO:probinson] Available to: Everyone (Tier I)
	GS171902: HP:0010987 Abnormality of cellular immune system Figure Label: HP:0010987 Species: Homo sapiens  Data Points: 285  Description: "An abnormality of the morphology or counts of the cells that make up the `immune system` (FMA:9825)." [HPO:probinson] Available to: Everyone (Tier I)
	GS171452: HP:0008775 Abnormality of the prostate Figure Label: HP:0008775 Species: Homo sapiens  Data Points: 5  Description: "An abnormality of the `prostate` (FMA:9600)." [HPO:probinson] Available to: Everyone (Tier I)
	GS176718: HP:0000078 Abnormality of the genital system Figure Label: HP:0000078 Species: Homo sapiens  Data Points: 602  Description: "An abnormality of the `genital system` (FMA:7160)." [HPO:probinson] Available to: Everyone (Tier I)
	GS176817: HP:0011446 Abnormality of higher mental function Figure Label: HP:0011446 Species: Homo sapiens  Data Points: 1213  Description: "Cognitive, psychiatric or memory anomaly." [DDD:ajackson] Available to: Everyone (Tier I)
	GS205002: GO:0048856 anatomical structure development Figure Label: GO:0048856 Species: Homo sapiens  Data Points: 4024  Description: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021, GOC:mtg_15jun06] Available to: Everyone (Tier I)
	GS170931: HP:0001287 Meningitis Figure Label: HP:0001287 Species: Homo sapiens  Data Points: 28  Description: "`Inflammation` (MPATH:212) of the `meninges` (FMA:231572)." [HPO:probinson] Available to: Everyone (Tier I)
	GS197443: GO:0032549 ribonucleoside binding Figure Label: GO:0032549 Species: Homo sapiens  Data Points: 1840  Description: "Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose." [GOC:mah] Available to: Everyone (Tier I)
	GS173335: HP:0004363 Abnormality of calcium homeostasis Figure Label: HP:0004363 Species: Homo sapiens  Data Points: 58  Description: "An abnormality of `calcium ion homeostasis` (GO:0055074)." [HPO:probinson] Available to: Everyone (Tier I)
	GS163263: MP:0003762 abnormal immune organ physiology Figure Label: MP:0003762 Species: Mus musculus  Data Points: 201  Description: "any functional anomaly of the organs of the immune system" [MGI:csmith] Available to: Everyone (Tier I)
	GS166746: MP:0002224 abnormal spleen size Figure Label: MP:0002224 Species: Mus musculus  Data Points: 829  Description: "deviation from the normal spleen size" [MGI:cwg] Available to: Everyone (Tier I)
	GS174494: HP:0002564 Malformation of the heart and great vessels Figure Label: HP:0002564 Species: Homo sapiens  Data Points: 533  Description: "Congenital malformation of the heart or great vessels (i.e., the large blood vesslesentering and leaving the heart: aorta, the pulmonary arteries and veins, and the superior and inferior vena cava)." [HPO:probinson] Available to: Everyone (Tier I)
	GS173014: HP:0010936 Abnormality of the lower urinary tract Figure Label: HP:0010936 Species: Homo sapiens  Data Points: 264  Description: "An abnormality of the `lower urinary tract` (FMA:45659)." [HPO:probinson] Available to: Everyone (Tier I)
	GS201730: GO:0002252 immune effector process Figure Label: GO:0002252 Species: Homo sapiens  Data Points: 465  Description: "Any process of the immune system that can potentially contribute to an immune response." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149] Available to: Everyone (Tier I)
	GS207857: GO:0009058 biosynthetic process Figure Label: GO:0009058 Species: Homo sapiens  Data Points: 5223  Description: "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." [GOC:curators, ISBN:0198547684] Available to: Everyone (Tier I)
	GS163956: MP:0011180 abnormal hematopoietic cell number Figure Label: MP:0011180 Species: Mus musculus  Data Points: 1756  Description: "any anomaly in the expected number of cells of the hematopoietic lineage" [CL:0000988, MGI:csmith] Available to: Everyone (Tier I)
	GS206191: GO:0048584 positive regulation of response to stimulus Figure Label: GO:0048584 Species: Homo sapiens  Data Points: 1084  Description: "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] Available to: Everyone (Tier I)
	GS201023: GO:0071704 organic substance metabolic process Figure Label: GO:0071704 Species: Homo sapiens  Data Points: 9005  Description: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [CHEBI:50860, GOC:mah] Available to: Everyone (Tier I)
	GS196595: GO:0006464 cellular protein modification process Figure Label: GO:0006464 Species: Homo sapiens  Data Points: 2464  Description: "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." [GOC:go_curators] Available to: Everyone (Tier I)
	GS166706: MP:0002166 altered tumor susceptibility Figure Label: MP:0002166 Species: Mus musculus  Data Points: 1292  Description: "greater than or less than the average number of tumors, usually a specific type, arising in a given organism when compared to controls" [MGI:csmith] Available to: Everyone (Tier I)
	GS171893: HP:0011458 Abdominal symptom Figure Label: HP:0011458 Species: Homo sapiens  Data Points: 473  Description: Abdominal symptom Available to: Everyone (Tier I)
	GS184566: GO:0019538 protein metabolic process Figure Label: GO:0019538 Species: Mus musculus  Data Points: 3548  Description: "The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification." [GOC:ma] Available to: Everyone (Tier I)
	GS170964: HP:0000152 Abnormality of head and neck Figure Label: HP:0000152 Species: Homo sapiens  Data Points: 1223  Description: "An abnormality of `head and neck` (FMA:280881)." [HPO:probinson] Available to: Everyone (Tier I)
	GS175260: HP:0002732 Lymph node hypoplasia Figure Label: HP:0002732 Species: Homo sapiens  Data Points: 4  Description: "Underdevelopment of the `lymph nodes` (FMA:5034)." [HPO:probinson] Available to: Everyone (Tier I)
	GS191106: GO:0044464 cell part Figure Label: GO:0044464 Species: Mus musculus  Data Points: 13186  Description: "Any constituent part of a cell, the basic structural and functional unit of all organisms." [GOC:jl] Available to: Everyone (Tier I)
	GS173290: HP:0011354 Generalized abnormality of skin Figure Label: HP:0011354 Species: Homo sapiens  Data Points: 739  Description: "An abnormality of the skin that is not localized to any one particular region." [DDD:cmoss] Available to: Everyone (Tier I)
	GS178123: GO:0004715 non-membrane spanning protein tyrosine kinase activity Figure Label: GO:0004715 Species: Mus musculus  Data Points: 43  Description: "Catalysis of the reaction: ATP + a non-membrane spanning protein L-tyrosine = ADP + a non-membrane spanning protein L-tyrosine phosphate." [EC:2.7.10.2] Available to: Everyone (Tier I)
	GS179517: GO:0012501 programmed cell death Figure Label: GO:0012501 Species: Mus musculus  Data Points: 1371  Description: "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell." [GOC:lr, GOC:mtg_apoptosis] Available to: Everyone (Tier I)
	GS206020: GO:0045621 positive regulation of lymphocyte differentiation Figure Label: GO:0045621 Species: Homo sapiens  Data Points: 64  Description: "Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] Available to: Everyone (Tier I)
	GS167997: MP:0002406 increased susceptibility to infection Figure Label: MP:0002406 Species: Mus musculus  Data Points: 464  Description: "greater likelihood that an organism will develop ill effects from a pathogenic invasion or from components of or toxins produced by pathogens" [ISBN:0-683-40008-8, MGI:cwg] Available to: Everyone (Tier I)
	GS186227: GO:0090304 nucleic acid metabolic process Figure Label: GO:0090304 Species: Mus musculus  Data Points: 3599  Description: "Any cellular metabolic process involving nucleic acids." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS172031: HP:0000364 Hearing abnormality Figure Label: HP:0000364 Species: Homo sapiens  Data Points: 592  Description: "An abnormality of the `sensory perception of sound` (GO:0007605)." [HPO:probinson] Available to: Everyone (Tier I)
	GS167991: MP:0002401 abnormal lymphopoiesis Figure Label: MP:0002401 Species: Mus musculus  Data Points: 1029  Description: "atypical formation of lymphocytes and plasma cells from lymphoid stem cells which develop from the pluripotent hematopoietic stem cells in the bone marrow; lymphoid stem cells differentiate into T-lymphocytes; B-lymphocytes; plasma cells; or NK-cells (natural killer cells), depending on the organ or tissues to which they migrate" [MESH:G04.335.151.825.597.500] Available to: Everyone (Tier I)
	GS204612: GO:0019222 regulation of metabolic process Figure Label: GO:0019222 Species: Homo sapiens  Data Points: 4811  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] Available to: Everyone (Tier I)
	GS210168: GO:0030098 lymphocyte differentiation Figure Label: GO:0030098 Species: Homo sapiens  Data Points: 223  Description: "The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:go_curators] Available to: Everyone (Tier I)
	GS172416: HP:0002242 Abnormality of the intestine Figure Label: HP:0002242 Species: Homo sapiens  Data Points: 303  Description: "An abnormality of the `intestine` (FMA:7199). The closely related term enteropathy is used to refer to any disease of the intestine." [HPO:probinson] Available to: Everyone (Tier I)
	GS181533: GO:0046872 metal ion binding Figure Label: GO:0046872 Species: Mus musculus  Data Points: 3442  Description: "Interacting selectively and non-covalently with any metal ion." [GOC:ai] Available to: Everyone (Tier I)
	GS162887: MP:0006043 decreased apoptosis Figure Label: MP:0006043 Species: Mus musculus  Data Points: 267  Description: "less than normal cell death" [MGI:smb, RGD:cur] Available to: Everyone (Tier I)
	GS163857: MP:0005065 abnormal neutrophil morphology Figure Label: MP:0005065 Species: Mus musculus  Data Points: 258  Description: "any structural anomaly of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes" [CL:0000775, ISBN:0721601464] Available to: Everyone (Tier I)
	GS166065: MP:0009337 abnormal splenocyte number Figure Label: MP:0009337 Species: Mus musculus  Data Points: 57  Description: "deviation from the expected number of cells of the spleen" [MGI:csmith] Available to: Everyone (Tier I)
	GS165421: MP:0002497 increased IgE level Figure Label: MP:0002497 Species: Mus musculus  Data Points: 98  Description: "greater than normal immunoglobulin class E level" [MGI:cwg] Available to: Everyone (Tier I)
	GS177862: GO:0001775 cell activation Figure Label: GO:0001775 Species: Mus musculus  Data Points: 607  Description: "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:mgi_curators] Available to: Everyone (Tier I)
	GS170460: MP:0008217 abnormal B cell activation Figure Label: MP:0008217 Species: Mus musculus  Data Points: 208  Description: "any anomaly in the normal change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific" [GO:0002312, MGI:csmith] Available to: Everyone (Tier I)
	GS195502: GO:0007249 I-kappaB kinase/NF-kappaB cascade Figure Label: GO:0007249 Species: Homo sapiens  Data Points: 215  Description: "The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription." [GOC:bf, GOC:jl, PMID:12773372, Reactome:REACT_13696.1] Available to: Everyone (Tier I)
	GS204819: GO:0002819 regulation of adaptive immune response Figure Label: GO:0002819 Species: Homo sapiens  Data Points: 90  Description: "Any process that modulates the frequency, rate, or extent of an adaptive immune response." [GOC:add] Available to: Everyone (Tier I)
	GS200844: GO:0031347 regulation of defense response Figure Label: GO:0031347 Species: Homo sapiens  Data Points: 426  Description: "Any process that modulates the frequency, rate or extent of a defense response." [GOC:mah] Available to: Everyone (Tier I)
	GS164133: MP:0005076 abnormal cell differentiation Figure Label: MP:0005076 Species: Mus musculus  Data Points: 1571  Description: "anomaly in the process whereby relatively unspecialized cells, e. g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history" [MGI:cwg] Available to: Everyone (Tier I)
	GS170748: MP:0005025 abnormal response to infection Figure Label: MP:0005025 Species: Mus musculus  Data Points: 665  Description: "any anomaly in the body's reaction to invasion and multiplication of microorganisms in its tissues, or the body's reaction to components of or toxins produced by pathogenic microorganisms" [MGI:cwg] Available to: Everyone (Tier I)
	GS168563: MP:0002425 altered susceptibility to autoimmune disorder Figure Label: MP:0002425 Species: Mus musculus  Data Points: 480  Description: "a change in the likelihood that an organism will develop disease characterized by production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides" [MESH:C20.111] Available to: Everyone (Tier I)
	GS165024: MP:0008203 absent B-1a cells Figure Label: MP:0008203 Species: Mus musculus  Data Points: 13  Description: "absence of the B-1 B cell subset bearing the CD5 surface marker" [CL:0000820, PMID:11861604] Available to: Everyone (Tier I)
	GS169133: MP:0002442 abnormal leukocyte physiology Figure Label: MP:0002442 Species: Mus musculus  Data Points: 1546  Description: "any functional anomaly of any of the white blood cells (basophils, eosinophils, neutrophils, lymphocytes, or monocytes)" [ISBN:0-683-40008-8, MGI:cwg] Available to: Everyone (Tier I)
	GS203607: GO:0034654 nucleobase-containing compound biosynthetic process Figure Label: GO:0034654 Species: Homo sapiens  Data Points: 3573  Description: "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah] Available to: Everyone (Tier I)
	GS178155: GO:0008219 cell death Figure Label: GO:0008219 Species: Mus musculus  Data Points: 1457  Description: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as "apoptotic bodies"); and/or (3) its corpse (or its fragments) have been engulfed by an adjacent cell in vivo." [GOC:mah, GOC:mtg_apoptosis] Available to: Everyone (Tier I)
	GS168710: MP:0001648 abnormal apoptosis Figure Label: MP:0001648 Species: Mus musculus  Data Points: 1258  Description: "excessive or absent cell death in a particular tissue or cell type" [ISBN:0-683-40008-8, MGI:csmith] Available to: Everyone (Tier I)
	GS185585: GO:0044710 single-organism metabolic process Figure Label: GO:0044710 Species: Mus musculus  Data Points: 8414  Description: "A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism." [GOC:jl] Available to: Everyone (Tier I)
	GS173137: HP:0011821 Abnormality of facial skeleton Figure Label: HP:0011821 Species: Homo sapiens  Data Points: 397  Description: "An abnormality of one or more of the set of bones that make up the `facial skeleton` (FMA:53673)." [DDD:awilkie] Available to: Everyone (Tier I)
	GS193632: GO:0051649 establishment of localization in cell Figure Label: GO:0051649 Species: Mus musculus  Data Points: 1366  Description: "The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell." [GOC:ai, GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS162990: MP:0001807 decreased IgA level Figure Label: MP:0001807 Species: Mus musculus  Data Points: 62  Description: "less than normal immunoglobulin class A level" [MGI:cwg] Available to: Everyone (Tier I)
	GS208978: GO:0043169 cation binding Figure Label: GO:0043169 Species: Homo sapiens  Data Points: 4034  Description: "Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge." [GOC:jl] Available to: Everyone (Tier I)
	GS197349: GO:0050776 regulation of immune response Figure Label: GO:0050776 Species: Homo sapiens  Data Points: 555  Description: "Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] Available to: Everyone (Tier I)
	GS203735: GO:0019932 second-messenger-mediated signaling Figure Label: GO:0019932 Species: Homo sapiens  Data Points: 143  Description: "Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell." [GOC:signaling, ISBN:0815316194, PMID:15221855, Wikipedia:Second_messenger_system] Available to: Everyone (Tier I)
	GS176632: HP:0001903 Anemia Figure Label: HP:0001903 Species: Homo sapiens  Data Points: 223  Description: "A reduction in `erythrocytes` (CL:0000232) volume or hemoglobin concentration." [HPO:probinson] Available to: Everyone (Tier I)
	GS189388: GO:0016301 kinase activity Figure Label: GO:0016301 Species: Mus musculus  Data Points: 780  Description: "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS201800: GO:0032553 ribonucleotide binding Figure Label: GO:0032553 Species: Homo sapiens  Data Points: 1877  Description: "Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] Available to: Everyone (Tier I)
	GS195539: GO:0045089 positive regulation of innate immune response Figure Label: GO:0045089 Species: Homo sapiens  Data Points: 164  Description: "Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection." [GOC:ebc] Available to: Everyone (Tier I)
	GS164630: MP:0006298 abnormal platelet activation Figure Label: MP:0006298 Species: Mus musculus  Data Points: 76  Description: "anomaly in the series of progressive, overlapping events triggered by exposure of platelets to signals from subendothelial tissue, including shape change, adhesiveness, aggregation, and release reactions; when carried through to completion, these events lead to the formation of a stable hemostatic plug" [GO:0030168, MGI:smb] Available to: Everyone (Tier I)
	GS205338: GO:0051094 positive regulation of developmental process Figure Label: GO:0051094 Species: Homo sapiens  Data Points: 682  Description: "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai] Available to: Everyone (Tier I)
	GS173990: HP:0000502 Abnormality of the conjunctiva Figure Label: HP:0000502 Species: Homo sapiens  Data Points: 49  Description: "An abnormality of the `conjunctiva` (FMA:59011)." [HPO:curators] Available to: Everyone (Tier I)
	GS188651: GO:0001883 purine nucleoside binding Figure Label: GO:0001883 Species: Mus musculus  Data Points: 1736  Description: "Interacting selectively and non-covalently with a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose." [GOC:hjd] Available to: Everyone (Tier I)
	GS180156: GO:0065008 regulation of biological quality Figure Label: GO:0065008 Species: Mus musculus  Data Points: 2172  Description: "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] Available to: Everyone (Tier I)
	GS189484: GO:0023052 signaling Figure Label: GO:0023052 Species: Mus musculus  Data Points: 5111  Description: "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." [GOC:mtg_signal, GOC:mtg_signaling_feb11, GOC:signaling] Available to: Everyone (Tier I)
	GS208128: GO:0045088 regulation of innate immune response Figure Label: GO:0045088 Species: Homo sapiens  Data Points: 222  Description: "Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection." [GOC:ebc] Available to: Everyone (Tier I)
	GS202415: GO:0044710 single-organism metabolic process Figure Label: GO:0044710 Species: Homo sapiens  Data Points: 9213  Description: "A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism." [GOC:jl] Available to: Everyone (Tier I)
	GS206544: GO:2000112 regulation of cellular macromolecule biosynthetic process Figure Label: GO:2000112 Species: Homo sapiens  Data Points: 3118  Description: "Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process." [GOC:obol] Available to: Everyone (Tier I)
	GS169832: MP:0005381 digestive/alimentary phenotype Figure Label: MP:0005381 Species: Mus musculus  Data Points: 1402  Description: digestive/alimentary phenotype Available to: Everyone (Tier I)
	GS194133: GO:0005737 cytoplasm Figure Label: GO:0005737 Species: Homo sapiens  Data Points: 9128  Description: "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] Available to: Everyone (Tier I)
	GS165474: MP:0002723 abnormal immune serum protein physiology Figure Label: MP:0002723 Species: Mus musculus  Data Points: 1183  Description: "abnormal concentration or function of circulating immune proteins" [MGI:cwg] Available to: Everyone (Tier I)
	GS167627: MP:0005460 abnormal leukopoiesis Figure Label: MP:0005460 Species: Mus musculus  Data Points: 1109  Description: "any anomaly in the process of generating white blood cells (leukocytes) from the pluripotent hematopoietic stem cells of the bone marrow; two significant pathways generate various types of leukocytes: myelopoiesis, in which leukocytes in the blood are derived from myeloid stem cells, and lymphopoiesis, in which leukocytes of the lymphatic system (lymphocytes) are generated from lymphoid stem cells" [MESH:G04.335.151.825.597] Available to: Everyone (Tier I)
	GS194669: GO:0034134 toll-like receptor 2 signaling pathway Figure Label: GO:0034134 Species: Homo sapiens  Data Points: 72  Description: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 2." [GOC:add, PMID:16551253, PMID:17328678] Available to: Everyone (Tier I)
	GS175265: HP:0002733 Abnormality of the lymph nodes Figure Label: HP:0002733 Species: Homo sapiens  Data Points: 74  Description: "A `lymph node` (FMA:5034) abnormality." [HPO:probinson] Available to: Everyone (Tier I)
	GS189860: GO:0043167 ion binding Figure Label: GO:0043167 Species: Mus musculus  Data Points: 5225  Description: "Interacting selectively and non-covalently with ions, charged atoms or groups of atoms." [GOC:jl] Available to: Everyone (Tier I)
	GS200837: GO:0031349 positive regulation of defense response Figure Label: GO:0031349 Species: Homo sapiens  Data Points: 225  Description: "Any process that activates or increases the frequency, rate or extent of a defense response." [GOC:mah] Available to: Everyone (Tier I)
	GS206329: GO:0060255 regulation of macromolecule metabolic process Figure Label: GO:0060255 Species: Homo sapiens  Data Points: 4151  Description: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] Available to: Everyone (Tier I)
	GS195199: GO:0005634 nucleus Figure Label: GO:0005634 Species: Homo sapiens  Data Points: 5948  Description: "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] Available to: Everyone (Tier I)
	GS171752: HP:0001713 Abnormality of cardiac ventricle Figure Label: HP:0001713 Species: Homo sapiens  Data Points: 169  Description: "An abnormality of a `cardiac ventricle` (FMA:7100)." [HPO:probinson] Available to: Everyone (Tier I)
	GS191796: GO:0016740 transferase activity Figure Label: GO:0016740 Species: Mus musculus  Data Points: 1686  Description: "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732] Available to: Everyone (Tier I)
	GS162988: MP:0001805 decreased IgG level Figure Label: MP:0001805 Species: Mus musculus  Data Points: 266  Description: "less than normal immunoglobulin class G level" [MGI:cwg] Available to: Everyone (Tier I)
	GS189240: GO:2001141 regulation of RNA biosynthetic process Figure Label: GO:2001141 Species: Mus musculus  Data Points: 2540  Description: "Any process that modulates the frequency, rate or extent of RNA biosynthetic process." [GOC:dph] Available to: Everyone (Tier I)
	GS165386: MP:0001262 decreased body weight Figure Label: MP:0001262 Species: Mus musculus  Data Points: 1856  Description: "lower than normal average weight" [PMID:10709991] Available to: Everyone (Tier I)
	GS170020: MP:0008215 decreased immature B cell number Figure Label: MP:0008215 Species: Mus musculus  Data Points: 178  Description: "reduced number of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity" [ISBN:0-8153-1691-7, MGI:cwg] Available to: Everyone (Tier I)
	GS208914: GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity Figure Label: GO:0051091 Species: Homo sapiens  Data Points: 182  Description: "Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:ai] Available to: Everyone (Tier I)
	GS180021: GO:0046903 secretion Figure Label: GO:0046903 Species: Mus musculus  Data Points: 663  Description: "The controlled release of a substance by a cell, a group of cells, or a tissue." [GOC:ai] Available to: Everyone (Tier I)
	GS169774: MP:0001846 increased inflammatory response Figure Label: MP:0001846 Species: Mus musculus  Data Points: 1305  Description: "greater than expected response to injury, infection, or insult" [MGI:cwg] Available to: Everyone (Tier I)
	GS182325: GO:0051716 cellular response to stimulus Figure Label: GO:0051716 Species: Mus musculus  Data Points: 5654  Description: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." [GOC:bf, GOC:jl] Available to: Everyone (Tier I)
	GS185492: GO:0050789 regulation of biological process Figure Label: GO:0050789 Species: Mus musculus  Data Points: 8942  Description: "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:ai, GOC:go_curators] Available to: Everyone (Tier I)
	GS172364: HP:0003111 Abnormality of ion homeostasis Figure Label: HP:0003111 Species: Homo sapiens  Data Points: 117  Description: "Abnormality of the homeostasis (concentration) of a `monoatomic ion` (CHEBI:24867)." [HPO:probinson] Available to: Everyone (Tier I)
	GS170646: MP:0002343 abnormal lymph node cortex morphology Figure Label: MP:0002343 Species: Mus musculus  Data Points: 65  Description: "any structural anomaly in the outer area of the lymph node that has B and T cell domains" [ISBN:0-8153-1691-7, MGI:cwg] Available to: Everyone (Tier I)
	GS167714: MP:0002414 abnormal myeloblast morphology/development Figure Label: MP:0002414 Species: Mus musculus  Data Points: 1112  Description: "any structural anomaly of the cells found in the bone marrow that give rise to the granulocyte line of blood cells" [MGI:cwg] Available to: Everyone (Tier I)
	GS164790: MP:0008172 abnormal follicular B cell morphology Figure Label: MP:0008172 Species: Mus musculus  Data Points: 101  Description: "any structural anomaly of a resting mature B cell with distinct phenotypic characteristics (CD23-positive, CD21-positive) found typically in the B cell follicle region of the spleen and lymph nodes" [CL:0000843, ISBN:0781735149, MGI:csmith] Available to: Everyone (Tier I)
	GS205332: GO:0051092 positive regulation of NF-kappaB transcription factor activity Figure Label: GO:0051092 Species: Homo sapiens  Data Points: 104  Description: "Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB." [GOC:dph, GOC:tb, PMID:15087454, PMID:15170030] Available to: Everyone (Tier I)
	GS136883: testis weight (Tswt, Published QTL Chr X) Figure Label: QTL-Tswt-Mouse-Chr X Species: Mus musculus  Data Points: 301  Description: QTL associated with testis weight. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (136010201) Available to: Everyone (Tier I)
	GS192609: GO:0031982 vesicle Figure Label: GO:0031982 Species: Mus musculus  Data Points: 849  Description: "Any small, fluid-filled, spherical organelle enclosed by membrane or protein." [GOC:mah, GOC:pz] Available to: Everyone (Tier I)
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